Tropical Disease News and Research RSS Feed - Tropical Disease News and Research

Tropical diseases encompass all diseases that occur solely, or principally, in the tropics. In practice, the term is often taken to refer to infectious diseases that thrive in hot, humid conditions, such as malaria, leishmaniasis, schistosomiasis, onchocerciasis, lymphatic filariasis, Chagas disease, African trypanosomiasis, and dengue.
Study sheds light on current and potential treatment options for schistosomiasis

Study sheds light on current and potential treatment options for schistosomiasis

In a special free issue of Future Medicinal Chemistry, leading experts explore current and potential new treatment options for the deadly neglected tropical disease schistosomiasis. [More]
UC San Diego researchers receive NIH grant to test efficacy of Sanofi's pain drug in treating Chagas disease

UC San Diego researchers receive NIH grant to test efficacy of Sanofi's pain drug in treating Chagas disease

The National Center for Advancing Translational Sciences, part of the National Institutes of Health (NIH), has awarded James McKerrow, MD, PhD, director of the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, with a 2015 New Therapeutic Uses Award. [More]
New article highlights learnings gleaned from monitoring complex HIV clinical trials in Africa

New article highlights learnings gleaned from monitoring complex HIV clinical trials in Africa

A new article in Clinical Investigation highlights the learnings gleaned from monitoring several complex HIV clinical trials in Africa over a 15 year period. [More]
Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

Liverpool scientists complete genomics studies on multidrug resistant Typhoid fever in Africa

The team has completed two genomics studies on the tropical disease, a condition that is estimated to cause up to 30 million illnesses and over a quarter of a million deaths globally each year. [More]
Insect-borne diseases increase with warmer climate

Insect-borne diseases increase with warmer climate

Insects, such as mosquitoes and ticks, are responsible for transmitting a range of diseases, such as malaria, chikungunya, dengue fever, and West Nile virus. The risk of contracting such illnesses is generally only considered when booking an exotic holiday. However, experts from the Emergency Response Department at Public Health England have warned that climate change could allow such vector-borne diseases to emerge closer to home. [More]
Case Western Reserve professor urges action to eliminate yaws

Case Western Reserve professor urges action to eliminate yaws

Half a century ago, a concentrated global effort nearly wiped a disfiguring tropical disease from the face of the earth. Now, says Case Western Reserve's James W. Kazura, MD, it's time to complete the work. [More]
Scientists sequence genome of hookworm

Scientists sequence genome of hookworm

In an advance that may potentially lead to new treatments for parasitic hookworms, scientists at the University of Massachusetts Medical School and Cornell University have sequenced the genome of the hookworm, Ancylostoma ceylanicum. [More]
WHO urges affected countries to increase investment in tackling neglected tropical diseases

WHO urges affected countries to increase investment in tackling neglected tropical diseases

WHO urges affected countries to scale up their investment in tackling 17 neglected tropical diseases in order to improve the health and well-being of more than 1.5 billion people. This investment would represent as little as 0.1% of current domestic expenditure on health in affected low and middle income countries for the period 2015-2030. [More]
Scientists identify potential target to combat leishmaniasis

Scientists identify potential target to combat leishmaniasis

Research led by St. Jude Children's Research Hospital scientists has identified a potential target in the quest to develop a more effective treatment for leishmaniasis, a parasitic tropical disease that kills thousands and sickens more than 1 million people worldwide each year. [More]
DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

DNDi awarded USAID grant to develop new treatments for river blindness, elephantiasis

The Drugs for Neglected Diseases initiative has been awarded US$ 10 million by the United States Agency for International Development to develop new treatments for onchocerciasis (river blindness) and lymphatic filariasis (elephantiasis) - the first-ever USAID grant for neglected tropical disease research and development (R&D). [More]
Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Bayer, DNDi sign first agreement to develop new oral treatment for onchocerciasis

Bayer HealthCare and the Drugs for Neglected Diseases initiative (DNDi) have signed an agreement under which Bayer will provide the active ingredient emodepside to support DNDi in its effort to develop a new oral drug to treat river blindness (or onchocerciasis). The world's second leading infectious cause of blindness, river blindness is a neglected tropical disease caused by a filarial worm. [More]
Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Monash University, 60P Australia partner to develop Fenretinide drug for dengue fever

Monash University and 60P Australia Pty Ltd, a subsidiary of 60° Pharmaceuticals LLC, have announced today an exclusive partnering deal, with 60P obtaining rights to develop the drug Fenretinide for dengue fever. [More]
Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year. [More]
AfriCoLeish launches Phase III clinical study to test 2 treatments for HIV-VL co-infected patients

AfriCoLeish launches Phase III clinical study to test 2 treatments for HIV-VL co-infected patients

The international research & development (R&D) consortium, AfriCoLeish, formed by six research organizations from East Africa and Europe, has launched a Phase III clinical study to address the extreme difficulty in treating visceral leishmaniasis (VL) in patients who also are HIV-positive. [More]
Prevalence of NTDs in Latin American countries presents opportunity for US foreign policy

Prevalence of NTDs in Latin American countries presents opportunity for US foreign policy

Recently published prevalence estimates of neglected tropical diseases (NTDs) in five Latin American countries - Bolivia, Cuba, Ecuador, Nicaragua and Venezuela - could suggest a new direction for United States foreign policy in the region, according to a tropical-disease expert at Rice University's Baker Institute for Public Policy. [More]

Celgene Global Health, DNDi expand partnership to identify new drug candidates for NTDs

Celgene Global Health, a division of Celgene Corporation, and the Drugs for Neglected Diseases initiative strengthen their collaboration with a four-year Research Collaboration Agreement to identify and optimize new drug candidates for the treatment of neglected tropical diseases (NTDs). [More]
Researchers discover analgesic mechanism that prevents pain in Buruli ulcer patients

Researchers discover analgesic mechanism that prevents pain in Buruli ulcer patients

When the body receives an injury to the skin, a signal is sent to the brain, which generates a sensation of pain. [More]

Human impact on environment plays a larger role in spread of schistosomiasis, says study

National Museum of Natural History scientist Bert Van Bocxlaer and an international team of researchers revealed that anthropogenic changes in Africa's Lake Malaŵi are a driving force behind the increase of urogenital schistosomiasis, a debilitating tropical disease caused by parasitic flatworms. [More]
Researchers uncover mechanism that may help explain severe forms of schistosomiasis

Researchers uncover mechanism that may help explain severe forms of schistosomiasis

​Researchers at the Sackler School of Graduate Biomedical Sciences at Tufts and Tufts University School of Medicine (TUSM) have uncovered a mechanism that may help explain the severe forms of schistosomiasis, or snail fever, which is caused by schistosome worms and is one of the most prevalent parasitic diseases in the world. The study in mice, published online in The Journal of Immunology, may also offer targets for intervention and amelioration of the disease. [More]
TSRI scientists receive $2.3M to study viruses that cause tropical diseases

TSRI scientists receive $2.3M to study viruses that cause tropical diseases

The outbreak of dengue fever that infected some 20 people in Florida's Martin County late last year unnerved many who feared the tropical disease had once again established a foothold in Florida. The last outbreaks occurred in 2009 and 2010 in Key West—before that, the disease hadn't struck Florida in more than 70 years. [More]
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