Tropical diseases encompass all diseases that occur solely, or principally, in the tropics. In practice, the term is often taken to refer to infectious diseases that thrive in hot, humid conditions, such as malaria, leishmaniasis, schistosomiasis, onchocerciasis, lymphatic filariasis, Chagas disease, African trypanosomiasis, and dengue.
A pair of scientists at The University of Texas at El Paso is one step closer to developing the first ever clinical Chagas disease vaccine.
Diagnosing malaria has been a very time-consuming and error-prone process up to now. Together with his Dutch colleague Jan van den Boogaart, Professor Oliver Hayden from the Technical University of Munich has now developed an automated rapid blood test that provides an accurate diagnosis in almost 100 percent of cases.
Researchers have identified a metabolite 'signature' that can accurately distinguish typhoid from other fever-inducing tropical diseases using patient blood samples.
The Amazonian Center of Excellence for Malaria Research, headed by Joseph Vinetz, MD, professor of medicine and tropical disease specialist at University of California San Diego School of Medicine, will receive up to approximately $8.3 million over seven years from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health.
Since 2007, the World Health Organization (WHO) has been reporting outstanding success in dealing with neglected tropical diseases (NTDs) with 1 billion people estimated to have received treatments in 2015.
As the World Health Organization steps up its efforts to eradicate a once-rampant tropical disease, a University of Washington study suggests that monitoring, and potentially treating, the monkeys that co-exist with humans in affected parts of the world may be part of the global strategy.
Researchers at the George Washington University have developed a way to test recombinant vaccines for their ability to stay effective after years of storage.
A new generation of vaccines for neglected tropical diseases is moving into clinical trials, and understanding the long-term stability and effectiveness of these vaccines over periods of storage is key to their success.
Each year, about 2 million people contract leishmaniasis, a parasitic disease transmitted by the bite of a sand fly. The cutaneous form of the disease results in disfiguring skin ulcers that may take months or years to heal and in rare cases can become metastatic, causing major tissue damage.
Many infectious diseases are one and done; people get sick once and then they are protected from another bout of the same illness.
Gambian sleeping sickness - a deadly parasitic disease spread by tsetse flies - could be eliminated in six years in key regions in the Democratic Republic of Congo, according to new research by the University of Warwick.
I think innovation is one of those rather slippery terms that means different things to different people. First of all, I would make a distinction between innovations that are essentially about a new, physical product and innovations that are more to do with services or processes.
Boosting a protective protein to stabilize blood vessels weakened by malaria showed improved survival beyond that of antimalarial drugs alone in pre-clinical research.
Researchers at the University of Georgia are working to find the fastest way possible to treat and cure human African trypanosomiasis, long referred to as sleeping sickness. By working to improve chemical entities already tested in human clinical trials, they hope to have a faster route to field studies to treat the disease using drugs that can be administered orally to patients.
The first global-scale genetic study of Salmonella Enteritidis bacteria, which is a major cause of blood poisoning and death in Africa and food poisoning in the Western World, has discovered that there are in fact three separate types.
People infected with a parasitic worm called Wuchereria bancrofti in areas where HIV is endemic may be more likely to acquire HIV than people who are not infected with the worm, according to a new study in southwest Tanzania, published in The Lancet.
Lesions on arms and legs, deformed faces - yaws is a tropical disease that infects the skin, bones and cartilage. It is caused by the bacterium Treponema pallidum subspecies pertenue
Griffith University tropical disease researchers have joined together with a host of international laboratories to advance drug discovery for major topical diseases through the creation and testing of the Malaria Box.
Professor Albert Descoteaux of INRS-Institut Armand-Frappier Research Centre and his team have discovered novel virulence strategies employed by the Leishmania parasite.
Some autoimmune diseases and persistent infections are characterized by high levels of antibodies in the blood. But what are the causes of this hypergammaglobulinemia? A team headed by INRS's Professor Simona Stäger has successfully identified the mechanisms triggering the phenomenon.