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Tuberculosis (TB) is a bacterial infection caused by a germ called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but they can also damage other parts of the body. TB spreads through the air when a person with TB of the lungs or throat coughs, sneezes or talks. If you think you have been exposed, you should go to your doctor for tests as soon as possible. You are more likely to get TB if you have a weak immune system.
Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

A research team from Spain has prepared a Cochrane systematic review that explores the efficacy, safety, and adherence to fixed-dose combinations (FDCs) of drugs versus single-drug formulations to treat people who are newly diagnosed with tuberculosis (TB). [More]
GMU’s early-detection urine test works for Lyme disease, study shows

GMU’s early-detection urine test works for Lyme disease, study shows

After three years and 300 patients, George Mason University researchers have proof that their early-detection urine test for Lyme disease works. [More]
OpenZika project uses supercomputing power to identify potential drug candidates to cure Zika virus

OpenZika project uses supercomputing power to identify potential drug candidates to cure Zika virus

Rutgers is taking a leading role in an IBM-sponsored World Community Grid project that will use supercomputing power to identify potential drug candidates to cure the Zika virus. [More]
New skin test for TB infection proves safe, effective in clinical trials

New skin test for TB infection proves safe, effective in clinical trials

A new skin test for tuberculosis infection has proven safe, easy to administer and accurate in two Phase III clinical trials, according to research presented at the ATS 2016 International Conference. [More]
Single sputum sample approach to TB diagnosis provides rapid, accurate results

Single sputum sample approach to TB diagnosis provides rapid, accurate results

A streamlined approach to tuberculosis (TB) diagnosis requiring a single sputum sample and providing rapid, accurate results to patients proved feasible in rural Uganda, according to research presented at the ATS 2016 International Conference. [More]
Novel rapid diagnostic test and shorter treatment with better outcomes may benefit MDR-TB patients

Novel rapid diagnostic test and shorter treatment with better outcomes may benefit MDR-TB patients

New WHO recommendations aim to speed up detection and improve treatment outcomes for multidrug resistant tuberculosis (MDR-TB) through use of a novel rapid diagnostic test and a shorter, cheaper treatment regimen. [More]
Point-of-care test could help detect TB in HIV-positive individuals

Point-of-care test could help detect TB in HIV-positive individuals

An international review team has prepared a Cochrane systematic review to assess the accuracy of a point-of-care urine test for diagnosing and screening tuberculosis (TB) in people living with human immunodeficiency virus (HIV). [More]
Study shows short-term statin treatment does not benefit heart surgery patients

Study shows short-term statin treatment does not benefit heart surgery patients

Giving daily doses of statins for a few days before and after heart surgery does not prevent heart muscle damage or the development of atrial fibrillation (AF), according to an international clinical trial led by the University of Oxford and funded by the British Heart Foundation. [More]
Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

The Cochrane Infectious Diseases Group have carried out a review update to evaluate the effects of corticosteroids being used alongside anti-tuberculosis medication to treat people suffering from tuberculous meningitis. [More]
Scientists identify novel way of synthesising promising new antibiotic

Scientists identify novel way of synthesising promising new antibiotic

A novel way of synthesising a promising new antibiotic has been identified by scientists at the University of Bristol. By expressing the genes involved in the production of pleuromutilin in a different type of fungus, the researchers were able to increase production by more than 2,000 per cent. [More]
Infected mice can be better models for human diseases

Infected mice can be better models for human diseases

Vaccines and therapeutics developed using mice often don't work as expected in humans. New research at Washington University School of Medicine in St. Louis points to the near-sterile surroundings of laboratory mice as a key reason. [More]
Newly launched TB-PACTS could be a valuable tool to combat world's leading infectious killer

Newly launched TB-PACTS could be a valuable tool to combat world's leading infectious killer

The Critical Path Institute, the Special Programme for Research and Training in Tropical Diseases, TB Alliance, and St. George's, University of London, are pleased to announce the launch of the TB-Platform for Aggregation of Clinical TB Studies. [More]
Study describes precise mechanisms that enable TB bacteria to persist in the body

Study describes precise mechanisms that enable TB bacteria to persist in the body

Bacteria that cause tuberculosis trick immune cells meant to destroy them into hiding and feeding them instead. This is the result of a study led by researchers from NYU Langone Medical Center and published online April 18 in Nature Immunology. [More]
Developing countries face health financing crisis due to low domestic investment, stagnating international aid

Developing countries face health financing crisis due to low domestic investment, stagnating international aid

Two major studies published in The Lancet reveal the health financing crisis facing developing countries as a result of low domestic investment and stagnating international aid, which could leave millions of people without access to even the most basic health services. [More]
Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Researchers develop novel method to store microfluidic devices for CD4 T cell testing

Providing vital health care services to people in developing countries without reliable electricity, refrigeration and state-of-the-art medical equipment poses a number of challenges. Inspired by pregnancy tests, researchers from Florida Atlantic University, Stanford University, and Baskent University in Turkey, have developed a novel method to store microfluidic devices for CD4 T cell testing in extreme weather conditions for up to six months without refrigeration. [More]
New biomarker discovery could improve chances of developing effective TB vaccine

New biomarker discovery could improve chances of developing effective TB vaccine

A team of scientists led by Oxford University have made a discovery that could improve our chances of developing an effective vaccine against Tuberculosis. [More]
New data from studies evaluating diagnostic tools, therapies for infectious diseases released at ECCMID 2016

New data from studies evaluating diagnostic tools, therapies for infectious diseases released at ECCMID 2016

New data from ten late-breaking abstracts is released at ECCMID 2016 – the annual meeting of the European Society of Clinical Microbiology and Infectious Disease. [More]
New study suggests that Neanderthals across Europe may have diseases carried out of Africa

New study suggests that Neanderthals across Europe may have diseases carried out of Africa

A new study suggests that Neanderthals across Europe may well have been infected with diseases carried out of Africa by waves of anatomically modern humans, or Homo sapiens. As both were species of hominin, it would have been easier for pathogens to jump populations, say researchers. This might have contributed to the demise of Neanderthals. [More]
Keynotes announced for ECCMID 2016

Keynotes announced for ECCMID 2016

The European Society of Clinical Microbiology and Infectious Diseases (ESCMID) previews some of the keynote lectures at the 26th European Congress of Clinical Microbiology and Infectious Diseases (ECCMID). The globe’s most prominent infection specialists will be gathering at its annual congress in Amsterdam from 9 – 12 April 2016. [More]
New extended-release pills could reduce dosage frequency of some drugs

New extended-release pills could reduce dosage frequency of some drugs

Researchers from MIT and Brigham and Women's Hospital have designed a new type of pill that, once swallowed, can attach to the lining of the gastrointestinal tract and slowly release its contents. The tablet is engineered so that one side adheres to tissue, while the other repels food and liquids that would otherwise pull it away from the attachment site. [More]
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