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Tuberculosis (TB) is a bacterial infection caused by a germ called Mycobacterium tuberculosis. The bacteria usually attack the lungs, but they can also damage other parts of the body. TB spreads through the air when a person with TB of the lungs or throat coughs, sneezes or talks. If you think you have been exposed, you should go to your doctor for tests as soon as possible. You are more likely to get TB if you have a weak immune system.
WHO violated sound standards of TB medical care, researchers say

WHO violated sound standards of TB medical care, researchers say

The World Health Organization (WHO) violated sound standards of medical care and human rights by nudging poorer countries to follow less expensive, untested and largely ineffective treatment protocols for tuberculosis patients, a new paper by researchers at Duke, Brandeis and Harvard universities argues. [More]
New ultra-fast molecular method can help detect mycobacterial pathogens in the lungs

New ultra-fast molecular method can help detect mycobacterial pathogens in the lungs

What used to take several weeks is now possible in two days: Thanks to new molecular-based methods, mycobacterial pathogens that cause pulmonary infections or tuberculosis can now be detected much more quickly. [More]
Experts use next-generation genetic sequencing to diagnose suspected brain infections

Experts use next-generation genetic sequencing to diagnose suspected brain infections

In a proof-of-principle study, a team of physicians and bioinformatics experts at Johns Hopkins reports they were able to diagnose or rule out suspected brain infections using so called next-generation genetic sequencing of brain tissue samples. [More]
Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Molecular diagnostics of the future: an interview with Elaine Warburton, OBE

Firstly, a sample must be transported from the clinic to the laboratory. Simple tests may be undertaken in a small lab within the hospital or clinic, whilst complex testing such as drug susceptibility testing is often done in a large centralized laboratory many miles from the clinic [More]
How can we defeat drug resistance? An interview with Dr Grania Brigden

How can we defeat drug resistance? An interview with Dr Grania Brigden

The O’Neill report is a wide ranging report recognising anti-microbial resistance (AMR) as a global problem with major public health and economic significance. [More]
Genomic analysis can help public health investigators understand dynamics of TB outbreak

Genomic analysis can help public health investigators understand dynamics of TB outbreak

Using genome sequencing, researchers from the University of British Columbia, along with colleagues at the Imperial College in London, now have the ability to determine when a tuberculosis (TB) outbreak is over. [More]
Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding could be key to fight against antibiotic resistance

Tiny molecular scaffolding that joins molecules together could be the key to our battle against antibiotic resistance. Research published in Bioorganic & Medicinal Chemistry Letters shows that carbon nanodot scaffolding assembled with small molecules called polyamines can kill some dangerous drug-resistant bacteria, including Acinetobacter baumanii and Klebsiella pneumonia. [More]
Mathematical approach can help achieve optimal dosing for various drugs

Mathematical approach can help achieve optimal dosing for various drugs

In treating diseases with drugs, dosing is critical; too little is ineffective, while too much can be lethal. Colorado State University's Brad Reisfeld takes a mathematical approach to achieving optimal dosing for various drugs. [More]
New systems-based strategy may help accelerate TB drug discovery

New systems-based strategy may help accelerate TB drug discovery

The rise in multi-drug resistant (MDR) and extremely drug resistant (XDR) strains of Mycobacterium tuberculosis (MTB) is becoming a major cause of global health concern for treating tuberculosis, which affects a third of the global population. [More]
Giving chemotherapy after radiotherapy delays rare brain tumour growth

Giving chemotherapy after radiotherapy delays rare brain tumour growth

GIVING chemotherapy after radiotherapy delays further growth of a rare type of brain tumour, increasing the number of patients alive at five years from 44 per cent to 56 per cent. [More]
New, inexpensive blood test helps detect low levels of mycobacteria that causes bTB

New, inexpensive blood test helps detect low levels of mycobacteria that causes bTB

A new blood test to detect Mycobacteria in blood has been developed by a team at The University of Nottingham led by Dr Cath Rees, an expert in microbiology in the School of Biosciences and Dr Ben Swift from the School of Veterinary Medicine and Science. [More]
Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

Cochrane review explores FDCs versus single-drug formulations for treatment of pulmonary TB

A research team from Spain has prepared a Cochrane systematic review that explores the efficacy, safety, and adherence to fixed-dose combinations (FDCs) of drugs versus single-drug formulations to treat people who are newly diagnosed with tuberculosis (TB). [More]
GMU’s early-detection urine test works for Lyme disease, study shows

GMU’s early-detection urine test works for Lyme disease, study shows

After three years and 300 patients, George Mason University researchers have proof that their early-detection urine test for Lyme disease works. [More]
OpenZika project uses supercomputing power to identify potential drug candidates to cure Zika virus

OpenZika project uses supercomputing power to identify potential drug candidates to cure Zika virus

Rutgers is taking a leading role in an IBM-sponsored World Community Grid project that will use supercomputing power to identify potential drug candidates to cure the Zika virus. [More]
New skin test for TB infection proves safe, effective in clinical trials

New skin test for TB infection proves safe, effective in clinical trials

A new skin test for tuberculosis infection has proven safe, easy to administer and accurate in two Phase III clinical trials, according to research presented at the ATS 2016 International Conference. [More]
Single sputum sample approach to TB diagnosis provides rapid, accurate results

Single sputum sample approach to TB diagnosis provides rapid, accurate results

A streamlined approach to tuberculosis (TB) diagnosis requiring a single sputum sample and providing rapid, accurate results to patients proved feasible in rural Uganda, according to research presented at the ATS 2016 International Conference. [More]
Novel rapid diagnostic test and shorter treatment with better outcomes may benefit MDR-TB patients

Novel rapid diagnostic test and shorter treatment with better outcomes may benefit MDR-TB patients

New WHO recommendations aim to speed up detection and improve treatment outcomes for multidrug resistant tuberculosis (MDR-TB) through use of a novel rapid diagnostic test and a shorter, cheaper treatment regimen. [More]
Point-of-care test could help detect TB in HIV-positive individuals

Point-of-care test could help detect TB in HIV-positive individuals

An international review team has prepared a Cochrane systematic review to assess the accuracy of a point-of-care urine test for diagnosing and screening tuberculosis (TB) in people living with human immunodeficiency virus (HIV). [More]
Study shows short-term statin treatment does not benefit heart surgery patients

Study shows short-term statin treatment does not benefit heart surgery patients

Giving daily doses of statins for a few days before and after heart surgery does not prevent heart muscle damage or the development of atrial fibrillation (AF), according to an international clinical trial led by the University of Oxford and funded by the British Heart Foundation. [More]
Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

Study evaluates effects of corticosteroids along with anti-tuberculosis drugs in tuberculous meningitis

The Cochrane Infectious Diseases Group have carried out a review update to evaluate the effects of corticosteroids being used alongside anti-tuberculosis medication to treat people suffering from tuberculous meningitis. [More]
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