Tumorigenesis News and Research

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Tumorigenesis is the process involved in the production of a new tumor or tumors.

Senescent macrophages in the lung promote tumor growth, study finds

Macrophages are a type of white blood cell that are among the body's first line of defense against infection. In addition to killing harmful microorganisms, macrophages typically can initiate a response against tumors.

25 Sep 2023

Mesenchymal stem cell-derived extracellular vesicles show promise in PCOS treatment

Polycystic ovary syndrome (PCOS) is a pervasive endocrine disorder that affects millions of women globally, impacting their hormonal balance, fertility and overall well-being.

12 Sep 2023

Exploring the anti-cancer potential of dark tea

The potential of dark tea in cancer prevention and management.

11 Sep 2023

Study finds association between high dietary phosphorus and breast cancer

Researchers evaluated associations of breast cancer incidence with different dietary phosphate levels.

30 Aug 2023

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Researchers demonstrated that the crosstalk between IL1RL1+ regulatory T-cells (Treg) and cancer-associated fibroblasts (CAFs) drives the tissue repairing.

30 Aug 2023

Non-traditional gene fusions in luminal breast cancer: A new target for therapy

A new editorial paper was published in Oncotarget's Volume 14 on June 12, 2023, entitled, "Are cis-spliced fusion proteins pathological in more aggressive luminal breast cancer?"

21 Aug 2023

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

Researchers describe molecular signalling regulated by mTOR among memory and exhausted cytotoxic CD8+ T lymphocytes.

18 Aug 2023

New insights into the role of liver progenitor cells in liver cancer initiation

Primary liver cancers ranked as the sixth most commonly diagnosed cancers and the third leading cause of cancer-related death in 2020. Among all primary liver cancers, HCC is the most common cancer, accounting for more than 80% of cases with a 5-year survival rate of less than 10% in Western countries.

17 Aug 2023

Gut microbiota could affect the responsiveness and efficacy of cancer treatment

A vast number of microbes colonizes the human body to form an ecological community known as the microbiota. Microbiota are made up of bacteria, viruses, fungi, and archaea.

11 Aug 2023

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Researchers described the dual role of cell cycle and apoptosis regulator 2 (CCAR2) in cancer progression as a tumor suppressor and promoter.

4 Aug 2023

Two new compounds can block cancer cell’s escape route

Cancer cells are capable of escaping chemotherapy and radiotherapy by activating a signaling pathway that prevents them from dying.

27 Jul 2023

An evaluation of the main nanotechnology approaches to improve the therapeutic potential of polyphenols against cancer

Researchers comprehensively evaluated all nanotechnology-based approaches.

18 Jul 2023

Aerobic glycolysis essential for eye development in mammals, study finds

Aerobic glycolysis, the process by which cells transform glucose into lactate, is key for eye development in mammals, according to a new Northwestern Medicine study published in Nature Communications.

14 Jul 2023

Pyroptosis: A potential therapeutic target for lung cancer

Lung cancer, one of the most aggressive forms of cancer, continues to be a leading cause of death worldwide. Although several new therapies have been developed for this disease, it has a poor prognosis in its advanced stages.

28 Jun 2023

Study offers novel insights into the evolution of multiple myeloma

A new study by researchers at The University of Texas MD Anderson Cancer Center highlights novel insights into the evolution of multiple myeloma from precursor disease, which may help better identify patients likely to progress and develop new interventions.

12 Jun 2023

Tumorigenesis News and Research

Senescent macrophages in the lung promote tumor growth, study finds

Mesenchymal stem cell-derived extracellular vesicles show promise in PCOS treatment

Exploring the anti-cancer potential of dark tea

Study finds association between high dietary phosphorus and breast cancer

Unlocking tumor immune evasion: IL1RL1+ Treg cells and CAFs collaborate for immunotherapy resistance

Non-traditional gene fusions in luminal breast cancer: A new target for therapy

Regulation of cytotoxic T-cell differentiation and exhaustion by mTOR signaling

New insights into the role of liver progenitor cells in liver cancer initiation

Gut microbiota could affect the responsiveness and efficacy of cancer treatment

Recent advances in the understanding of the role and mechanism of CCAR2 in cancer

Two new compounds can block cancer cell’s escape route

An evaluation of the main nanotechnology approaches to improve the therapeutic potential of polyphenols against cancer

Aerobic glycolysis essential for eye development in mammals, study finds

Pyroptosis: A potential therapeutic target for lung cancer

Study offers novel insights into the evolution of multiple myeloma

Groundbreaking study targets 'jumping genes' in the entire genomes of the human large intestine

GPR141 drives breast tumorigenesis by inducing tumor cell properties via the p-mTOR1/p53 axis

Exploiting platelets for antitumor drug delivery and immune modulation of tumor microenvironment

New CRISPR genome-editing technology helps scientists to explore many cancer-linked mutations

Research sheds light on the early cellular events that give rise to pancreatic cancer

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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