Type 1 Diabetes

Type 1 diabetes, formerly called juvenile diabetes or insulin-dependent diabetes, is usually first diagnosed in children, teenagers, or young adults. In this form of diabetes, the beta cells of the pancreas no longer make insulin because the body’s immune system has attacked and destroyed them. Treatment for type 1 diabetes includes taking insulin shots or using an insulin pump, making wise food choices, exercising regularly, controlling blood pressure and cholesterol, and taking aspirin daily—for some.

What is Type 1 Diabetes?

Type 1 diabetes mellitus describes a condition where the body cannot produce insulin which leads to a very high level of blood sugar and associated complications. The condition, which usually develops in childhood or adolescence, affects millions of people worldwide.

Diabetes Mellitus Type 1 Pathophysiology

Diabetes Mellitus Type 1 Inheritance

Type 1 Diabetes Treatment

Type 1 Diabetes Cure

Type 1 Diabetes Prevention

Type 1 Diabetes Research

Does the 'Stomach Flu' Vaccine Prevent Type I Diabetes?

Latest Type 1 Diabetes News and Research

Managing diabetes with probiotics and synbiotics

Systematic review in Clinical Nutrition analyzed randomized trials to assess the impact of prebiotics and synbiotics on glycemic control in diabetes, revealing significant benefits in fasting glucose, serum insulin, and HbA1C levels.

16 Apr 2024

Gut flora disruption in infancy linked to autism and ADHD

Disturbed gut flora during the first years of life is associated with diagnoses such as autism and ADHD later in life.

3 Apr 2024

Systemic Inflammation Index: A new hope for autoimmune disease management

A routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of debilitating autoimmune diseases.

2 Apr 2024

Vegan diet benefits individuals with type 1 diabetes, study shows

A low-fat vegan diet rich in fruits, vegetables, grains, and beans reduces insulin needs and improves insulin sensitivity and glycemic control in people with type 1 diabetes, according to a first-of-its-kind study by the Physicians Committee for Responsible Medicine published in Clinical Diabetes.

29 Mar 2024

Early understanding of diabetes risk could help in better disease management

With diabetes increasing at an alarming rate in the United States, Diabetes Alert Day is meant to be a one-day "wake-up call" to the seriousness of diabetes and the importance of understanding your risk.

28 Mar 2024

Study finds changing trends in arterial disease risk among diabetics

There has been a redistribution in the risk of arterial disease in type 1 and 2 diabetes. The risks of heart attack and stroke have decreased significantly, while complications in more peripheral vessels have increased in relative importance, according to studies at the University of Gothenburg.

28 Mar 2024

NIH funds $12.5 million initiative to create the world's first integrated pancreas knowledgebase

Leading investigators in diabetes, pancreas and islet biology, and computational biology have received $12.5 million in two five-year awards from the National Institutes of Health to create the world's first, integrated knowledgebase of human-derived tissue- and cellular-level pancreatic information to support innovative, collaborative and reproducible research.

25 Mar 2024

After Appalachian hospitals merged into a monopoly, their ERs slowed to a crawl

In the small Appalachian city of Bristol, Virginia, City Council member Neal Osborne left a meeting on the morning of Jan. 3 and rushed himself to the hospital.

25 Mar 2024

Study evaluates the use of tirzepatide in overweight/obese adults with type 1 diabetes

A new study in the peer-reviewed journal Diabetes Technology & Therapeutics (DTT) evaluated the use of tirzepatide in overweight/obese adults with type 1 diabetes.

22 Mar 2024

Study reveals protective role of C3 protein in insulin-producing cells

Although there are many differences between type 1 diabetes and type 2 diabetes, there are also similarities, such as inflammation of the insulin-producing cells.

21 Mar 2024

From farm to pharmacy: Transgenic cow milk as a new source of human insulin

A team of researchers from Brazil constructed a lentivirus vector with expression specific for mammary glands and carrying the gene for human insulin.

21 Mar 2024

Glucose fluctuations impact cognitive function in people with Type 1 Diabetes

A new study led by researchers at McLean Hospital (a member of Mass General Brigham) and Washington State University used advances in digital testing to demonstrate that naturally occurring glucose fluctuations impact cognitive function in people with Type 1 Diabetes (T1D).

18 Mar 2024

Study reveals key mechanism of PD-1 function

Insights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengthened to improve their anticancer effect, a new study shows.

9 Mar 2024

Pregnant women with autoimmune conditions at a greater risk of developing adverse pregnancy outcomes, study suggests

Researchers analyzed systematic reviews conducted on the association between autoimmune diseases and pregnancy outcomes.

8 Mar 2024

Is there a higher risk of depression among specific populations of patients with rheumatoid arthritis?

Researchers assessed the risk of depression following the diagnosis of rheumatoid arthritis (RA).

8 Mar 2024

Breakthrough in CRISPR delivery promises safer gene editing

Recent research in PNAS highlights advancements in non-viral, cell-specific delivery methods for CRISPR-Cas systems, emphasizing their potential to enhance research and gene therapy applications by minimizing risks associated with off-target effects and improving targeted delivery.

7 Mar 2024

Breakthrough research unveils β-cell dynamics in Type 1 diabetes

About eight million people live with Type 1 diabetes (T1D) worldwide, a chronic autoimmune condition in which the body attacks and destroys its own insulin-producing β-cells (pronounced "beta") in the pancreas, leading to a lack of insulin and inability to regulate blood sugar.

26 Feb 2024

Decoding the genetic links between diabetes, hyperlipidemia, and IBD

Announcing a new publication for Acta Materia Medica journal. Previous epidemiologic studies have shown a close association between type 1 diabetes mellitus (T1DM), hyperlipidemia, and inflammatory bowel disease (IBD), but the causal relationship has not been established.

23 Feb 2024

Automated insulin delivery systems: Advancements and future prospects

A special 13-article supplement to the peer-reviewed journal Diabetes Technology & Therapeutics (DTT) examines the "Development and Future of Automated Insulin Delivery (AID) Systems.

23 Feb 2024

Innovative MicroGlucagon solution aims to transform insulin therapy for type 1 diabetics

Researchers in Trondheim are developing a new medicine for diabetics who have to have daily injections of insulin. The key is a hormone that causes the smallest blood vessels to relax on the inside.

22 Feb 2024