Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Mice study shows role of yeast in aggravating IBD symptoms

Mice study shows role of yeast in aggravating IBD symptoms

New, low-cost biosimilar for IBD therapy shows efficacy and safety

New, low-cost biosimilar for IBD therapy shows efficacy and safety

Incidence of inflammatory bowel disease continues to increase in Denmark, research reveals

Incidence of inflammatory bowel disease continues to increase in Denmark, research reveals

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

New research provides clues to how antibody treatment led to remission in SIV-infected monkeys

New research provides clues to how antibody treatment led to remission in SIV-infected monkeys

IBD patients have less stable gut microbiome than healthy people, study shows

IBD patients have less stable gut microbiome than healthy people, study shows

Food: the good, the bad and the ugly

Food: the good, the bad and the ugly

UT Southwestern scientists discover gene that protects gut from IBD

UT Southwestern scientists discover gene that protects gut from IBD

Study finds new links between human genome and inflammation tracers

Study finds new links between human genome and inflammation tracers

Impact of IBS on patients

Impact of IBS on patients

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

Researchers develop first sensor that can identify IBD and distinguish between two subtypes

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

MMP9 enzyme could suppress tumors in colitis associated cancer, new study finds

New diet could treat pediatric patients with Crohn's disease, ulcerative colitis

New diet could treat pediatric patients with Crohn's disease, ulcerative colitis

New research offers valuable insight for developing more effective drugs to treat IBD

New research offers valuable insight for developing more effective drugs to treat IBD

Study identifies four previously unknown genetic risk locations for primary sclerosing cholangitis

Study identifies four previously unknown genetic risk locations for primary sclerosing cholangitis

Researchers reveal key role of bacteria-binding protein in intestine

Researchers reveal key role of bacteria-binding protein in intestine

DNA changes in blood samples could pave way for simple tests to diagnose IBD

DNA changes in blood samples could pave way for simple tests to diagnose IBD