Ulcerative Colitis News and Research RSS Feed - Ulcerative Colitis News and Research

Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Researchers reveal key role of bacteria-binding protein in intestine

Researchers reveal key role of bacteria-binding protein in intestine

Deficiency in a certain protein in the gastrointestinal tract has been shown to lead to both inflammation and abdominal fat accumulation in mice. [More]
DNA changes in blood samples could pave way for simple tests to diagnose IBD

DNA changes in blood samples could pave way for simple tests to diagnose IBD

Scientists have identified chemical changes in the DNA of patients with inflammatory bowel diseases that could improve screening for the conditions. [More]
FDA approves new assay for diagnosis of IBD

FDA approves new assay for diagnosis of IBD

Inova Diagnostics, a worldwide leader in autoimmune diagnostic reagents and systems for the clinical laboratory, is pleased to announce the US Food and Drug Administration clearance of QUANTA Lite Calprotectin Extended Range, an assay which aids in the diagnosis of Inflammatory Bowel Disease (IBD), and can help differentiate IBD from Irritable Bowel Syndrome (IBS). [More]
Identifying foods that trigger IBS: an interview with Dr Bill Chey

Identifying foods that trigger IBS: an interview with Dr Bill Chey

IBS is a common medical condition which is diagnosed in the presence of characteristic gastrointestinal symptoms including recurring bouts of abdominal pain and diarrhea and/or constipation. IBS patients also commonly report bloating and abdominal distension or swelling. [More]
Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Regular consumption of dietary emulsifiers promotes colorectal cancer in mice

Emulsifiers, which are added to most processed foods to aid texture and extend shelf life, can alter intestinal bacteria in a manner that promotes intestinal inflammation and colorectal cancer, according to a new study. [More]
Researchers create new culture model of human intestine to study inflammatory bowel disease

Researchers create new culture model of human intestine to study inflammatory bowel disease

Inflammatory bowel disease (IBD) is a complex condition that requires a lifetime of care and increases a person's cancer risk. [More]
Takeda, Marvel Custom Solutions unveil four new Super Hero characters at London Comic Con

Takeda, Marvel Custom Solutions unveil four new Super Hero characters at London Comic Con

Takeda Pharmaceuticals Company Limited along with the support of Marvel Custom Solutions today announces the launch of four new Super Hero characters and the first chapter of a new graphic comic book at the popular London Comic Con, 28th – 30th October 2016. [More]
Many ulcerative colitis patients with anemia do not receive testing and treatment, study reports

Many ulcerative colitis patients with anemia do not receive testing and treatment, study reports

Many patients with ulcerative colitis don't receive recommended testing and treatment for the common problem of iron deficiency anemia, reports a study in the October issue of Inflammatory Bowel Diseases, official journal of the Crohn's & Colitis Foundation of America (CCFA). The journal is published by Wolters Kluwer. [More]
Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit develops therapy for Crohn's disease perianal fistulas

Esperite's business unit The Cell Factory in collaboration with Women's and Children's Health Department of the University of Padua and the Padua University Hospital are developing therapies for inflammatory bowel disease (IBD) using extracellular vesicles (EVs). [More]
Researchers identify genomic regions linked to ulcerative colitis in African-Americans

Researchers identify genomic regions linked to ulcerative colitis in African-Americans

In the first genome-wide association study of genetic risk factors for inflammatory bowel disease in African Americans, a research team has identified two regions of the genome (loci) associated with ulcerative colitis only in people of African descent. [More]
IBD diagnosis in childhood does not affect educational achievements and lifestyle, study finds

IBD diagnosis in childhood does not affect educational achievements and lifestyle, study finds

Twenty-five percent of inflammatory bowel disease (IBD) patients are diagnosed as children or adolescents -- at the peak of their social and educational development. [More]
Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Scientists at NIH and Emory University induce sustained remission in SIV-infected monkeys

Scientists at the National Institutes of Health and Emory University have experimentally induced sustained remission of SIV, the simian form of HIV, in infected monkeys. [More]
Alternative therapies appear to be effective in ameliorating IBS symptoms

Alternative therapies appear to be effective in ameliorating IBS symptoms

A new review looks at the evidence behind the effectiveness of complementary or alternative therapies-including probiotics, prebiotics, synbiotics, fiber, and herbal medicinal products-for the treatment of bowel disorders such as irritable bowel syndrome (IBS), functional constipation, and ulcerative colitis. [More]
FDA approves new biosimilar for multiple inflammatory diseases

FDA approves new biosimilar for multiple inflammatory diseases

The U.S. Food and Drug Administration today approved Amjevita (adalimumab-atto) as a biosimilar to Humira (adalimumab) for multiple inflammatory diseases. [More]
Study suggests interactions between distant DNA regions may impact disease gene levels

Study suggests interactions between distant DNA regions may impact disease gene levels

A person's DNA sequence can provide a lot of information about how genes are turned on and off, but new research out of Case Western Reserve University School of Medicine suggests the 3-D structure DNA forms as it crams into cells may provide an additional layer of gene control. [More]
Hamilton researchers conduct ground-breaking new trial on pediatric fecal transplant for IBD

Hamilton researchers conduct ground-breaking new trial on pediatric fecal transplant for IBD

Hamilton researchers are conducting a ground-breaking new trial looking at fecal transplants to help treat inflammatory bowel disease (IBD) in children. [More]
Crohn's disease sufferers experience slower cognitive response times, study shows

Crohn's disease sufferers experience slower cognitive response times, study shows

New research published in the UEG Journal1 has found that Crohn's disease sufferers experience slower response times than matched individuals that do not have the disease. [More]
Ginger-derived nanoparticles may be good medicine for inflammatory bowel disease

Ginger-derived nanoparticles may be good medicine for inflammatory bowel disease

A recent study by researchers at the Atlanta Veterans Affairs Medical Center took them to a not-so-likely destination: local farmers markets. They went in search of fresh ginger root. [More]
Battling IBD with super heroes: an interview with Dr James Lindsay

Battling IBD with super heroes: an interview with Dr James Lindsay

Takeda Pharmaceutical Company Limited has launched IBD Unmasked as a first-of-its-kind global initiative designed to raise awareness of the unsung Super Heroes of the global IBD community. [More]
Research sheds new light on development of chronic inflammatory diseases

Research sheds new light on development of chronic inflammatory diseases

Research from life scientists at The University of Manchester has shone new light on the way cells tune in to different inflammatory signals to understand what is happening in the body. [More]
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