Ulcerative Colitis News and Research

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Ulcerative colitis is a common inflammatory disease of the colon characterized by inflammation and ulceration of the large bowel and rectum. The condition impairs the ability of the large bowel to absorb water which results in diarrhea, the main symptom of the condition.

Ulcerative colitis is a relapsing and remitting condition, meaning symptoms can die down for long periods but then flare-up from time to time. These flare-ups can be sudden and severe. During a period of relapse, symptoms may include bloody diarrhea, abdominal pain and a sudden urge to defecate. Other symptoms include wind, loss of appetite, weight loss, fever and fatigue.

Currently, there is no cure for the condition apart from surgery. However, certain treatments such as corticosteroids or immunosuppressants may be used to ease symptoms by reducing inflammation. Surgery for severe ulcerative colitis that does not respond to treatment involves completely removing the large bowel and re-routing the small bowel so that waste can still be expelled. This procedure is called a colectomy.

In the UK, the incidence of ulcerative colitis is around 1 in 500 and the condition is equally common among males and females. Symptoms can develop at any age, but onset usually occurs between 15 and 30 years of age.
Study shows safety, efficacy of endoscopic needle knife therapy for intestinal strictures in IBD patients

Study shows safety, efficacy of endoscopic needle knife therapy for intestinal strictures in IBD patients

Researchers discover new mechanism that causes chronic intestinal inflammation

Researchers discover new mechanism that causes chronic intestinal inflammation

Pairing curcumin with turmeric essential oils offers better protection from ulcerative colitis, study finds

Pairing curcumin with turmeric essential oils offers better protection from ulcerative colitis, study finds

Fecal microbiota transplant may be effective treatment option for ulcerative colitis, research suggests

Fecal microbiota transplant may be effective treatment option for ulcerative colitis, research suggests

Dietary soy-protein may be effective adjunct therapy for inflammatory bowel diseases

Dietary soy-protein may be effective adjunct therapy for inflammatory bowel diseases

Cytokine plays critical role in driving immune cells to promote or suppress inflammatory bowel disease

Cytokine plays critical role in driving immune cells to promote or suppress inflammatory bowel disease

UC Riverside professor receives grant to explore therapeutic target for treating IBD patients

UC Riverside professor receives grant to explore therapeutic target for treating IBD patients

Synthetic biologists engineer gut bacteria capable of sensing colitis

Synthetic biologists engineer gut bacteria capable of sensing colitis

IBD patients with longer duration of disease have higher risk of developing NAFLD

IBD patients with longer duration of disease have higher risk of developing NAFLD

Yoga may be valuable adjunct to conventional therapies for ulcerative colitis

Yoga may be valuable adjunct to conventional therapies for ulcerative colitis

Fighting colorectal cancer

Fighting colorectal cancer

Health psychologists now treating gastrointestinal disorders strongly affected by stress

Health psychologists now treating gastrointestinal disorders strongly affected by stress

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Study shows efficacy of biologics for mucosal healing in Crohn's disease and ulcerative colitis

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Beneficial bacteria may be key to reverse gut inflammation seen in inflammatory bowel diseases

Mice study shows role of yeast in aggravating IBD symptoms

Mice study shows role of yeast in aggravating IBD symptoms

New, low-cost biosimilar for IBD therapy shows efficacy and safety

New, low-cost biosimilar for IBD therapy shows efficacy and safety

Incidence of inflammatory bowel disease continues to increase in Denmark, research reveals

Incidence of inflammatory bowel disease continues to increase in Denmark, research reveals

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

Lower vitamin D levels increase risk of clinical relapse in Ulcerative Colitis patients, study finds

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

Research: Many ulcerative colitis patients taking conventional treatments describe disease as 'poorly controlled'

New research provides clues to how antibody treatment led to remission in SIV-infected monkeys

New research provides clues to how antibody treatment led to remission in SIV-infected monkeys