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Unlocking intrinsically disordered proteins: an interview with Peter Wright

Unlocking intrinsically disordered proteins: an interview with Peter Wright

I'm a professor in the Department of Integrative Structural and Computational Biology at The Scripps Research Institute. I have been performing NMR research on proteins for nearly 40 years. [More]
Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

Zepatier receives FDA approval for treatment of chronic HCV genotypes 1 and 4 infections

The U.S. Food and Drug Administration today approved Zepatier (elbasvir and grazoprevir) with or without ribavirin for the treatment of chronic hepatitis C virus (HCV) genotypes 1 and 4 infections in adult patients. [More]
Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

Leading researchers reject proposed link between adeno-associated virus 2 and hepatocellular carcinoma

The conclusion drawn from a recent study that insertion of adeno-associated virus 2 (AAV2) into human DNA causes mutations leading to the development of hepatocellular carcinoma (HCC) was resoundingly rejected by leading researchers in the fields of gene therapy and molecular genetics. [More]
Measles vaccination plays key role in reducing child mortality

Measles vaccination plays key role in reducing child mortality

The number of measles-related deaths has decreased 79% from 546 800 at the beginning of the century to 114 900 in 2014. New data released by WHO for the Measles & Rubella Initiative, estimates that 17.1 million lives have been saved since 2000, largely due to increased vaccination coverage against this highly contagious viral disease. [More]
First-ever genomic study shows dengue may survive year-round in southern China

First-ever genomic study shows dengue may survive year-round in southern China

The first-ever comprehensive genomic analysis of the virus that causes dengue fever suggests that it may survive year-round in southern China. [More]
Gene therapy restores visual function in mouse model of LCA1

Gene therapy restores visual function in mouse model of LCA1

Mice lacking the protein retGC1, which is deficient in humans suffering Leber congenital amaurosis-1 (LCA1), a disorder that causes severe visual impairment beginning in infancy, received gene therapy to replace retGC1 and showed fully restored visual function that persisted for at least 6 months. [More]
60P to commence Phase II clinical trial among dengue fever patients

60P to commence Phase II clinical trial among dengue fever patients

60 Degrees Pharmaceuticals, a company focused on development of therapeutics for tropical diseases, and Singapore General Hospital announced today that the Hospital has received a grant from Singapore's National Medical Research Council to support a Phase II clinical trial among dengue fever patients. [More]
Ledipasvir/sofosbuvir combination approved for hepatitis C treatment does not require antiviral drug

Ledipasvir/sofosbuvir combination approved for hepatitis C treatment does not require antiviral drug

The drug approved to treat patients infected with the hepatitis C virus needs no help from other antivirals, according to a study released online this week in the journal Hepatology. [More]
Two South Dakota State University researchers awarded NASA grant to combat West Nile virus

Two South Dakota State University researchers awarded NASA grant to combat West Nile virus

Through a three-year NASA grant, two South Dakota State University researchers will help mosquito control officials use mosquito surveillance and environmental data to target West Nile virus. [More]
BRIM, Janssen announce strategic collaboration to develop effective treatment for dengue

BRIM, Janssen announce strategic collaboration to develop effective treatment for dengue

BRIM Biotechnology, Inc., announced today that it has entered a Collaboration, Option and License Agreement with Janssen Pharmaceutica N.V., one of the Janssen Pharmaceutical Companies of Johnson & Johnson. [More]
MIPT researchers develop ultrasensitive nanomechanical sensor to identify tumor markers

MIPT researchers develop ultrasensitive nanomechanical sensor to identify tumor markers

Two young researchers working at the MIPT Laboratory of Nanooptics and Plasmonics, Dmitry Fedyanin and Yury Stebunov, have developed an ultracompact highly sensitive nanomechanical sensor for analyzing the chemical composition of substances and detecting biological objects, such as viral disease markers, which appear when the immune system responds to incurable or hard-to-cure diseases, including HIV, hepatitis, herpes, and many others. [More]
AWMSG recommends Daklinza (daclatasvir) for treatment of adult patients with chronic HCV infection

AWMSG recommends Daklinza (daclatasvir) for treatment of adult patients with chronic HCV infection

The All Wales Medicines Strategy Group has recommended Daklinza (daclatasvir) for the treatment of adult patients with chronic hepatitis C virus (HCV) infection. The recommendation is specifically for patients with advanced liver disease, for whom treatment options can be limited. [More]
Liberia conducts first polio, measles immunizations since Ebola outbreak.

Liberia conducts first polio, measles immunizations since Ebola outbreak.

A week-long campaign to vaccinate more than 600,000 children against polio and measles kicks off today in Liberia... [More]
International science team pave way for fast and accurate diagnosis of the influenza virus

International science team pave way for fast and accurate diagnosis of the influenza virus

Statistics indicate that, on average, adults over the age of 30 only contract the influenza virus twice in a decade – but far more frequently (self) misdiagnose a cold virus (commonly rhinovirus or coronavirus) as being the flu... [More]
New review highlights future research initiatives to eradicate polio

New review highlights future research initiatives to eradicate polio

April 12th 2015 marks the 60th anniversary of the publication of Jonas Salk's landmark polio vaccine trial results, which confirmed that the first vaccine against polio was safe and effective. A new review, which was published online ahead of print in Future Microbiology, provides a comprehensive overview of current polio vaccines, and highlights new and future research initiatives, such as new vaccine formulations, that could help ensure that polio is eradicated and eradication is maintained. [More]
World-first human clinical trials for Hendra virus to begin this month

World-first human clinical trials for Hendra virus to begin this month

An antibody manufactured at The University of Queensland will be used in world-first human Hendra virus clinical trials starting this month. [More]
Clinical study launched to evaluate effectiveness of new HCV therapy in Washington, D.C.

Clinical study launched to evaluate effectiveness of new HCV therapy in Washington, D.C.

Officials from the National Institutes of Health and the city of Washington, D.C., launched a clinical trial to examine whether primary care physicians and other health care providers, such as nurse practitioners and physician assistants, can use a new antiviral therapy as effectively as specialist physicians to treat people with hepatitis C virus (HCV) infection. [More]
WHO urges affected countries to increase investment in tackling neglected tropical diseases

WHO urges affected countries to increase investment in tackling neglected tropical diseases

WHO urges affected countries to scale up their investment in tackling 17 neglected tropical diseases in order to improve the health and well-being of more than 1.5 billion people. This investment would represent as little as 0.1% of current domestic expenditure on health in affected low and middle income countries for the period 2015-2030. [More]
Rutgers patient gets second chance at life following liver transplant

Rutgers patient gets second chance at life following liver transplant

Mati Muñoz is 65 years old - filled with the enthusiastic energy that comes with a second chance at life. A decade ago, says Muñoz, who lives in Woodbridge Township, N.J., her liver was being destroyed by hepatitis C, a viral disease she believes she contracted as a girl in her native Cuba from a poorly sterilized needle used in a medical procedure. [More]
Two researchers receive Pioneer Award from Human Gene Therapy

Two researchers receive Pioneer Award from Human Gene Therapy

Recognized for their pioneering work in the development of gene transfer technology using retroviral vectors to deliver therapeutic genes into cells, Richard C. Mulligan, PhD, Director of the Harvard Gene Therapy Initiative, Harvard Institutes of Medicine, Boston, MA, and A. Dusty Miller, PhD, Fred Hutchinson Cancer Research Center, Seattle, WA, received the Pioneer Award from Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
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