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New gene therapy shows promising results for treating neurodegenerative disorders

New gene therapy shows promising results for treating neurodegenerative disorders

A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains of treated mice, restored enzyme function, and extended survival by about 2.5-fold. [More]
Epclusa drug receives FDA approval for treating adult patients with chronic HCV

Epclusa drug receives FDA approval for treating adult patients with chronic HCV

The U.S. Food and Drug Administration approved Epclusa to treat adult patients with chronic hepatitis C virus (HCV) both with and without cirrhosis (advanced liver disease). [More]
Southern Europe may be at risk of Zika outbreaks during this summer

Southern Europe may be at risk of Zika outbreaks during this summer

Established Aedes-mosquito population could spread the Zika virus in Europe this summer if infected travelers introduce the virus. An analysis of temperatures, vectorial capacity, basic reproductive number (R0), and air traveler flows suggests parts of Southern Europe may be at risk for Zika outbreaks between June and August. [More]
Experts at EAN Congress discuss spread of Zika virus threat across Europe

Experts at EAN Congress discuss spread of Zika virus threat across Europe

The Zika epidemic has long assumed global proportions, experts told the Congress of the European Academy of Neurology in Copenhagen. Europe needs to get prepared to deal with the relentless spread of the health threat, in particular with a view to "imported" infection. [More]
Scientists discover how Zika virus replicates in the placenta

Scientists discover how Zika virus replicates in the placenta

Zika virus can infect and replicate in immune cells from the placenta, without killing them, scientists have discovered. The finding may explain how the virus can pass through the placenta of a pregnant woman, on its way to infect developing brain cells in her fetus. [More]
Meta-genomics analysis tool Taxonomer can rapidly and accurately detect pathogens

Meta-genomics analysis tool Taxonomer can rapidly and accurately detect pathogens

Scientists at the University of Utah, ARUP Laboratories, and IDbyDNA, Inc., have developed ultra-fast, meta-genomics analysis software called Taxonomer that dramatically improves the accuracy and speed of pathogen detection. [More]
Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Zika virus infection may cause ocular problems in Brazilian infants with microcephaly

Researchers studying babies with a Zika virus-related birth defect say they have found previously unreported eye problems possibly linked to the virus that could result in severe visual impairment. [More]
New approach offers unprecedented view of how HIV virus infects and appropriates host cell

New approach offers unprecedented view of how HIV virus infects and appropriates host cell

Viruses attack cells and commandeer their machinery in a complex and carefully orchestrated invasion. Scientists have longed probed this process for insights into biology and disease, but essential details still remain out of reach. [More]
Research provides pathway toward creation of first broad-spectrum antiviral drug

Research provides pathway toward creation of first broad-spectrum antiviral drug

By studying the rare person -- about one in a million -- who can fight off viral infections more effectively than everyone else, investigators at the Icahn School of Medicine at Mount Sinai have developed a strategy to help the rest of us achieve this enhanced anti-viral state. [More]
lncRNA in placenta may help protect unborn baby from invading pathogens

lncRNA in placenta may help protect unborn baby from invading pathogens

The human placenta is an organ unlike any other. During the course of nine months it is formed by the embryo, sustains life and then is shed. [More]
Unique attributes of zebrafish may help study human blood disorders

Unique attributes of zebrafish may help study human blood disorders

Genetic regulation of the various types of blood cells in zebrafish and humans is highly similar, making it relatively easy and cost-effective to perform genetic, chemical, imaging and other molecular studies on this invaluable model organism to study normal hematopoetic development in humans as well as blood disorders and malignancies, as described in a Review article in Human Gene Therapy, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Globin gene transfer to treat beta-thalassemias shows promise in first clinical trial

Promising results from the first clinical trials of globin gene transfer to treat beta-thalassemias-inherited forms of anemia-have eliminated the need for blood transfusions in some individuals. [More]
Female sex hormone estradiol may protect women against sexually transmitted viral infections

Female sex hormone estradiol may protect women against sexually transmitted viral infections

A team of researchers led by McMaster University's Charu Kaushic has revealed for the first time how estradiol, a female sex hormone present during the menstrual cycle and found in oral contraceptives, may work to protect women against sexually transmitted viral infections. [More]
Respiratory tract infection in infants linked with increased T1D risk

Respiratory tract infection in infants linked with increased T1D risk

In a study appearing in the May 3, 2016 issue of JAMA, Anette-Gabriele Ziegler, M.D., of Helmholtz Zentrum Munchen, Munich, Germany, and colleagues examined associations between infection types during the first 2 years of life and between respiratory tract infections in the first 6 months and type l diabetes (T1D). Viral infections, particularly enteroviruses, have been hypothesized to cause T1D. Recent studies suggest that respiratory tract infections are associated with increased T1D risk if they are encountered within the first 6 months. [More]
Scientists develop new strategy to combat wide range of viruses

Scientists develop new strategy to combat wide range of viruses

Scientists and health officials are marshalling forces to fight Zika, the latest in a string of recent outbreaks. Many of these efforts target that virus specifically, but some researchers are looking for a broader approach. Now one team reports in ACS' journal Macromolecules a new strategy to fight a wide range of viruses that appears to be safe in vivo and could evade a virus's ability to develop resistance. [More]
Climate change, global travel may increase dengue epidemic risk

Climate change, global travel may increase dengue epidemic risk

Researchers at Umea University have developed a model for evidence-based predictions of the mosquito-borne dengue virus. Results show that global travel and climate change increase the risk for epidemics of dengue, and potentially other climate-sensitive infectious diseases carried by mosquitos, spreading into temperate areas. This according to a doctoral dissertation at Umeå University. [More]
WHO outlines steps to close immunization gap across countries during World Immunization Week 2016

WHO outlines steps to close immunization gap across countries during World Immunization Week 2016

During World Immunization Week 2016, held 24-30 April, the World Health Organization highlights recent gains in immunization coverage, and outlines further steps countries can take to “Close the Immunization Gap” and meet global vaccination targets by 2020. [More]
Cigarette smoking, viral infections may reduce effectiveness of COPD symptom-reliever medication

Cigarette smoking, viral infections may reduce effectiveness of COPD symptom-reliever medication

New study backs up observations in Chronic Obstructive Pulmonary Disease (COPD) patients showing reduced effectiveness of symptom-reliever medication (β2-adrenoceptor agonists) in flare-ups linked to cigarette smoking and infection with viruses such as influenza. [More]
Warming temperatures may increase risk for dengue outbreaks in Europe

Warming temperatures may increase risk for dengue outbreaks in Europe

Increasing temperatures will enlarge Europe's seasonal window for the potential spread of mosquito-borne viral disease, expanding the geographic areas at risk for a dengue epidemic to include much of Europe. The findings by researchers at Umea University in Sweden are published in the journal EBioMedicine. [More]
Cairn launches non-invasive Gastric Emptying Breath Test for measuring rate of gastroparesis in adults

Cairn launches non-invasive Gastric Emptying Breath Test for measuring rate of gastroparesis in adults

Cairn Diagnostics, formerly known as Advanced Breath Diagnostics (ABDiagnostics), has launched the 13C-Spirulina Gastric Emptying Breath Test (GEBT). [More]
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