Viral Vector News and Research

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Viral Vector is a type of virus used in cancer therapy. The virus is changed in the laboratory and cannot cause disease. Viral vectors may produce tumor antigens (proteins found on a tumor cell) to stimulate an antitumor immune response in the body. Viral vectors may also be used to carry genes that can change cancer cells back to normal cells.

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Researchers at Children's Hospital Los Angeles have received a nearly $1 million K08 grant from the National Institutes of Health (NIH)-; as well as funding from the U.S. Department of Defense-;to support studies into diffuse intrinsic pontine glioma (DIPG), a childhood brain tumor with a 0% survival rate.

16 Feb 2023

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

The latest generation of antidepressants relieves symptoms by mimicking steroids produced by the brain to ensure neurons are effectively talking to each other.

13 Feb 2023

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Researchers examined the factors associated with stroke following coronavirus disease 2019 (COVID-19) vaccination.

13 Feb 2023

Study shows that SARS-CoV-2 infection is associated with an increased risk for maternal morbidity and severe complications

Researchers examined vaccine effectiveness and pregnancy outcomes during the SARS-CoV-2 Omicron period.

23 Jan 2023

Vaccinated women well protected against severe COVID-19 symptoms, complications during pregnancy

The global network led by the Oxford Maternal and Perinatal Health Institute (OMPHI) at the University of Oxford has today published, in the Lancet, the results of the '2022 INTERCOVID Study' conducted in 41 hospitals across 18 countries.

19 Jan 2023

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

Researchers performed an observational study among COVID-19 patients and their close contacts registered with the Bangkok home health care services in Thailand.

18 Jan 2023

FUJIFILM Irvine Scientific launches HEK293 Feed, specifically designed for viral vector production

FUJIFILM Irvine Scientific, Inc., a world leader in the development and manufacture of serum-free and chemically defined cell culture media for bioproduction and cell therapy manufacturing, today announced the launch of its BalanCD HEK293 Viral Feed.

11 Jan 2023

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

A new study aimed to analyze whether the order of immunization of vaccine types impacted the efficacy of a heterologous prime-boost vaccination strategy.

6 Jan 2023

Decoding nucleic acid-based drugs and vaccines through SEC-SLS analysis

In this interview, Malvern Panalytical’s Product Technical Specialist, Stefan Cairns, discusses how SEC-SLS can be used to understand MRNA vector composition by referencing his latest publication.

From Malvern Panalytical 19 Dec 2022

XBB Omicron variant evades vaccine-induced immunity

A new study published in The Lancet Microbe examines the immune evasion characteristics of the Omicron XBB subvariant.

12 Dec 2022

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Gene therapies can treat, even potentially cure, certain genetic diseases, but it is challenging to deliver the treatments to the parts of the body where they are needed.

22 Nov 2022

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Researchers explored active and passive vaccination among children against respiratory syncytial virus (RSV).

22 Nov 2022

How lessons from the HIV epidemic can help combat COVID-19

Researchers revisit lessons learned from the HIV pandemic in response to COVID-19.

13 Nov 2022

Charles River Laboratories: New Center Expands Cell and Gene Therapy Capabilities

In this interview, Niall Dinwoodie, Executive Director for Gene Therapy for Charles River in Europe discusses the opening of their new HQ Plasmid Center of Excellence at Alderley Park.

From Charles River Laboratories, Inc. 4 Nov 2022

COVID-19 vaccines show favorable immunogenicity and efficacy in people living with HIV

In a recent study published in the International Journal of Infectious Diseases, researchers assessed the efficacy of coronavirus disease 2019 (COVID-19) vaccines in people living with human immunodeficiency virus (HIV).

16 Oct 2022

A rare case of Hashimoto encephalopathy after COVID vaccination

In a recent ‘Letter to the Editor’ published in the English edition of the journal Neurologandiacute, researchers reported the rare occurrence of Hashimoto encephalopathy in a recipient of the (COVID-19) vaccine Spikevax. Spikevax, research name mRNA-1273, is a COVID-19 vaccine based on the messenger ribonucleic acid (mRNA) technology.

16 Oct 2022

Transition in the management of COVID-19

A review of the current approaches to managing COVID-19, including diagnostic, therapeutic, and preventive measures.

16 Oct 2022

Review says dose of approved COVID-19 vaccines based on weak evidence

A recent study posted to the medRxiv* preprint server reviewed early-phase dose-finding trials to examine the study design, safety, and early antibody response data on approved coronavirus disease 2019 (COVID-19) vaccines and gain insights on design improvements for future candidate COVID-19 vaccine clinical trials.

26 Sep 2022

Study describes the dynamics of immune responses to triple COVID-19 vaccination

The effectiveness of the three-dose COVID-19 vaccination against SARS-CoV-2 and its variants has been described in detail in a recent study.

23 Sep 2022

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Monon Bioventures LLC has received a one-year, $398,314 Phase I Small Business Innovation Research, or SBIR grant from the National Cancer Institute to demonstrate the feasibility of manufacturing a glioblastoma therapeutic created at the Purdue University College of Pharmacy.

22 Sep 2022

Viral Vector News and Research

Further Reading

CHLA researchers receive funding to support studies into diffuse intrinsic pontine glioma

Behavioral deficits associated with chronic stress involve impaired neurosteroid synthesis and signaling

SARS-CoV-2 infection and Ad26.COV2.S vaccination may increase risk of stroke post-vaccination

Study shows that SARS-CoV-2 infection is associated with an increased risk for maternal morbidity and severe complications

Vaccinated women well protected against severe COVID-19 symptoms, complications during pregnancy

T-cell immunity and antibody responses against SARS-CoV-2 among individuals registered in the Bangkok home health care service

FUJIFILM Irvine Scientific launches HEK293 Feed, specifically designed for viral vector production

Does the immunization order of vaccine types influence the efficacy of heterologous prime-boost vaccination, especially mRNA and protein-based vaccines?

Decoding nucleic acid-based drugs and vaccines through SEC-SLS analysis

XBB Omicron variant evades vaccine-induced immunity

New family of adeno-associated viral vectors found to be better at delivering genetic cargo

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

How lessons from the HIV epidemic can help combat COVID-19

Charles River Laboratories: New Center Expands Cell and Gene Therapy Capabilities

COVID-19 vaccines show favorable immunogenicity and efficacy in people living with HIV

A rare case of Hashimoto encephalopathy after COVID vaccination

Transition in the management of COVID-19

Review says dose of approved COVID-19 vaccines based on weak evidence

Study describes the dynamics of immune responses to triple COVID-19 vaccination

Monon Bioventures receives SBIR grant to develop glioblastoma therapeutic created at Purdue

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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