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Controlling cholesterol metabolism could help reduce pancreatic cancer spread

Controlling cholesterol metabolism could help reduce pancreatic cancer spread

Researchers have shown how controlling cholesterol metabolism in pancreatic cancer cells reduces metastasis, pointing to a potential new treatment using drugs previously developed for atherosclerosis. [More]
New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

New nanoparticle approach can deliver antiobesity drugs directly to fat tissue

Researchers at MIT and Brigham and Women's Hospital have developed nanoparticles that can deliver antiobesity drugs directly to fat tissue. Overweight mice treated with these nanoparticles lost 10 percent of their body weight over 25 days, without showing any negative side effects. [More]
Half-strength apple juice followed by preferred fluid choice better for treating kids with mild gastroenteritis

Half-strength apple juice followed by preferred fluid choice better for treating kids with mild gastroenteritis

Children with mild gastroenteritis and minimal dehydration experienced fewer treatment failures such as IV rehydration or hospitalization when offered half-strength apple juice followed by their preferred fluid choice compared with children who received electrolyte maintenance solution to replace fluid losses, according to a study published online by JAMA. The study is being released to coincide with its presentation at the Pediatric Academic Societies meeting. [More]
Older women with chronic health problems more likely to have lower quality of life

Older women with chronic health problems more likely to have lower quality of life

Researchers writing in the Journal of the American Geriatrics Society recently learned that older women who are frail, and who have six or more chronic health conditions, are twice as likely to have a lower quality of life compared to women with less than three risk factors. [More]
Assessing body composition may help predict cardiovascular and total mortality

Assessing body composition may help predict cardiovascular and total mortality

Researchers from the David Geffen School of Medicine at UCLA found that cardiovascular disease patients who have high muscle mass and low fat mass have a lower mortality risk than those with other body compositions. The findings also suggest that regardless of a person's level of fat mass, a higher level of muscle mass helps reduce the risk of death. [More]
Antidepressant Wellbutrin linked to long-term modest weight loss

Antidepressant Wellbutrin linked to long-term modest weight loss

Group Health researchers have found that bupropion (marketed as Wellbutrin) is the only antidepressant that tends to be linked to long-term modest weight loss. [More]
TNF-alpha protein involved in autoimmune diseases may also promote tissue healing

TNF-alpha protein involved in autoimmune diseases may also promote tissue healing

As its name suggests, inflammatory bowel disease, which afflicts more than 1.6 million Americans, involves chronic inflammation of all or some of the digestive tract. An autoimmune disease known to have a strong genetic component, its symptoms are abdominal cramps, bloody diarrhea, and fever and, sometimes, weight loss. IBD, which is a group of inflammatory conditions, includes Crohn's disease and ulcerative colitis. [More]
MAILES study finds link between fatty diets and sleep

MAILES study finds link between fatty diets and sleep

University of Adelaide researchers have found that men who consume diets high in fat are more likely to feel sleepy during the day, to report sleep problems at night, and are also more likely to suffer from sleep apnea. [More]
Study offers clearer understanding of how obese people can sustain weight loss

Study offers clearer understanding of how obese people can sustain weight loss

Maintaining a stable weight loss is the biggest struggle for obese individuals, yet new research from University of Copenhagen have allowed researchers new insights into the complex processes involved in obesity and especially weight loss in obesity. It is now possible to offer overweight people a clearer understanding of how to sustain weight loss. [More]
Improving body clock could protect against metabolic syndrome

Improving body clock could protect against metabolic syndrome

Essential biological processes are managed by an internal timer or body clock. When the body clock gets out of whack, conditions such as metabolic syndrome can occur. [More]
Hospitals could reduce burden of alcohol-related liver disease through universal screening procedure

Hospitals could reduce burden of alcohol-related liver disease through universal screening procedure

The growing burden of alcohol-related liver disease (ARLD) could be reduced if hospitals introduced a simple universal screening procedure for those attending acute and emergency hospital settings, according to a new study shared today at The International Liver Congress in Barcelona, Spain. [More]
Rush awarded $14.5 million NIA grant to study effects of MIND diet on Alzheimer's disease

Rush awarded $14.5 million NIA grant to study effects of MIND diet on Alzheimer's disease

Can a particular diet prevent Alzheimer's disease? The National Institute of Aging has invested heavily in Rush University Medical Center to try to find out. [More]
Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

Mouse-based study shows exercise decreases cancer incidence, slows tumor growth

When you're pounding along an icy pavement or sweating through a gym workout, you try to remind yourself of the many health benefits of exercise. Between gasps, you can say that a healthy, fit lifestyle helps prevents obesity, a worldwide problem of increasing magnitude that has been linked to cardiovascular disease and diabetes. [More]
Health benefits of gastric bypass surgery start soon after procedure

Health benefits of gastric bypass surgery start soon after procedure

The health benefits of Roux-en Y gastric bypass surgery—a surgical weight-loss procedure in which the stomach is made smaller—start soon after the procedure. New research presented today at the Experimental Biology 2016 meeting in San Diego found that patients who underwent the procedure already showed some reductions in weight, waist circumference and body mass index one week after the procedure. [More]
Bariatric surgery improves pain, physical function in obese patients

Bariatric surgery improves pain, physical function in obese patients

Among a group of patients with severe obesity who underwent bariatric surgery, a large percentage experienced improvement in pain, physical function, and walking capacity over 3 years, according to a study appearing in the April 5 issue of JAMA. [More]
High-quality protein foods could be beneficial for obese people looking to reduce weight

High-quality protein foods could be beneficial for obese people looking to reduce weight

New research published in the Journal of Gerontology: Medical Sciences shows that eating more protein from foods like lean beef, as part of a reduced-calorie diet, can help obese older adults with limited ability to exercise to lose weight and increase physical function. This new research, supported by the Beef Checkoff, contributes to the growing body of evidence that shows lean beef and other high-quality protein foods are beneficial for health, including overweight and obese people looking to reduce weight. [More]
Liraglutide drug makes highly desirable foods less appealing to people

Liraglutide drug makes highly desirable foods less appealing to people

Understanding the motivations that drive humans to eat is an important consideration in the development of weight loss therapies. Now a study led by researchers at Beth Israel Deaconess Medical Center helps explain how the diabetes and weight loss drug liraglutide acts on brain receptors to make enticing foods seems less desirable. [More]
Pilot study shows mindfulness-based eating awareness training could help adolescents combat obesity

Pilot study shows mindfulness-based eating awareness training could help adolescents combat obesity

Some of the simplest, safest lessons to help adolescents combat obesity may be raising their awareness of what they are eating and whether they are even hungry, researchers say. [More]
Very few patients use FDA-approved medications for weight loss, new study suggests

Very few patients use FDA-approved medications for weight loss, new study suggests

Despite guidelines that advocate the use of weight loss medications to treat obesity, and the availability of FDA approved medications, very few patients use this treatment option, a new study suggests. The results will be presented Sunday, April 3, at ENDO 2016, the annual meeting of the Endocrine Society, in Boston. [More]
Bariatric arterial embolization safe, effective in sustaining weight loss in severely obese people

Bariatric arterial embolization safe, effective in sustaining weight loss in severely obese people

Findings from the early phase of a clinical trial led by Johns Hopkins investigators indicates that a new, minimally invasive weight loss treatment known as bariatric arterial embolization is safe and effective in sustaining weight loss in severely obese people. [More]
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