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West Nile virus is a potentially serious illness. Experts believe it is established as a seasonal epidemic in North America that flares up in the summer and continues into the fall. About one in 150 people infected with West Nile virus will develop severe illness. The severe symptoms can include high fever, headache, neck stiffness, stupor, disorientation, coma, tremors, convulsions, muscle weakness, vision loss, numbness and paralysis. These symptoms may last several weeks, and neurological effects may be permanent. Up to 20% of the people who become infected have symptoms such as fever, headache, body aches, nausea, vomiting, and sometimes swollen lymph glands or a skin rash on the chest, stomach and back. Symptoms can last for as short as a few days, though even healthy people have become sick for several weeks. Approximately 80% of people who are infected with West Nile virus will not show any symptoms at all.
APIC offers tips to stay infection-free

APIC offers tips to stay infection-free

Beyond the obvious—steering clear of runny noses and hacking coughs—the Association for Professionals in Infection Control and Epidemiology (APIC) presents some other practical ways of staying infection-free. [More]
Study helps explain why viruses often spread through the brain in patchwork patterns

Study helps explain why viruses often spread through the brain in patchwork patterns

Viruses often spread through the brain in patchwork patterns, infecting some cells but missing others. New research at Washington University School of Medicine in St. Louis helps explain why. The scientists showed that natural immune defenses that resist viral infection are turned on in some brain cells but switched off in others. [More]
Researchers observe how West Nile virus is transmitted between mosquito generations

Researchers observe how West Nile virus is transmitted between mosquito generations

In California Culex mosquitoes are considered to be the principle vectors of West Nile virus (WNV), which infects birds, humans, and other mammals during the summer. In addition, these mosquitoes may also serve as overwintering reservoir hosts as the virus is passed "vertically" from female mosquito to egg, then larva, and then adult. [More]
Biodiversity in large-scale ecosystems may also provide protection against diseases

Biodiversity in large-scale ecosystems may also provide protection against diseases

The richer the assortment of amphibian species in a pond, the more protection that community of frogs, toads and salamanders has against a parasitic infection that can cause severe deformities, including the growth of extra legs. [More]
Tat-beclin 1 shows promise against infections, neurodegenerative disorders and cancer

Tat-beclin 1 shows promise against infections, neurodegenerative disorders and cancer

UT Southwestern Medical Center scientists have synthesized a peptide that shows potential for pharmaceutical development into agents for treating infections, neurodegenerative disorders, and cancer through an ability to induce a cell-recycling process called autophagy. [More]
Rekom Biotech designs new biomarkers that can identify West Nile virus, dengue

Rekom Biotech designs new biomarkers that can identify West Nile virus, dengue

Researchers at the University of Granada have designed a set of biomarkers that can be used in diagnostic tests for the detection of dengue and the West Nile virus, two infectious diseases transmitted by the bite of a mosquito. These biomarkers can be used to identify these viral diseases, which affect millions of people worldwide. [More]
NIH's candidate vaccine safe in treating dengue

NIH's candidate vaccine safe in treating dengue

A candidate dengue vaccine developed by scientists at the National Institutes of Health (NIH) has been found to be safe and to stimulate a strong immune response in most vaccine recipients, according to results from an early-stage clinical trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH. The trial results were published online on January 17 in the Journal of Infectious Diseases. [More]

Broad range of human activities affects spread of vector-borne zoonotic diseases, experts say

West Nile virus, Lyme disease, dengue fever, and plague are examples of "vector-borne zoonotic diseases," caused by pathogens that naturally infect wildlife and are transmitted to humans by vectors such as mosquitoes or ticks. [More]

HCV medications' side effects can now be replicated and observed in Petri dishes and test tubes

The adverse side effects of certain hepatitis C medications can now be replicated and observed in Petri dishes and test tubes, thanks to a research team led by Craig Cameron, the Paul Berg Professor of Biochemistry and Molecular Biology at Penn State University. [More]
Alpha-herpesvirus axon-to-cell spread involves limited virion transmission

Alpha-herpesvirus axon-to-cell spread involves limited virion transmission

New research suggests that just one or two individual herpes virus particles attack a skin cell in the first stage of an outbreak, resulting in a bottleneck in which the infection may be vulnerable to medical treatment. [More]
New method of testing for West Nile virus

New method of testing for West Nile virus

While the United States has largely been spared the scourge of mosquito-borne diseases endemic to the developing world-including yellow fever, malaria and dengue fever-mosquito-related illnesses in the US are on the rise. One pathogen of increasing concern in the U.S. is an arbovirus known as West Nile. [More]
Viewpoints: 'Scrappy' debate offered little new on entitlement programs; Staring down the fiscal cliff

Viewpoints: 'Scrappy' debate offered little new on entitlement programs; Staring down the fiscal cliff

President Obama and Mitt Romney faced off Tuesday night in a scrappy, at times downright nasty town-hall debate that featured a feistier, more focused Obama than was seen in their first encounter and that broadened the discussion to social issues such as immigration, contraceptive coverage and gun control. ... In the end, on the domestic front, the debate performance of both has been about as disappointing as their dodging on the campaign trail. [More]
People need to protect themselves against West Nile virus

People need to protect themselves against West Nile virus

As this year's threat from the West Nile virus continues, one infectious diseases expert at the University of Alabama at Birmingham says a vaccine is not in our near future, so people need to protect themselves. [More]
Western Schools offers new 4th Edition West Nile Virus continuing education course for nurses

Western Schools offers new 4th Edition West Nile Virus continuing education course for nurses

West Nile virus is showing up earlier and producing more severe cases than normal this year, and nurses must be able to recognize who is at risk and how to best protect against it, an expert at Western Schools said today. [More]

Complacency and apathy may have played a role in recent spike of West Nile cases

With almost 1,600 cases of West Nile Virus and 66 mortalities reported to the Centers for Disease Control and Prevention (CDC) nationwide, officials are calling the recent West Nile virus outbreak the largest ever seen in the United States. [More]

CDC reports worst West Nile virus outbreak in the U.S.

This past year's mild winter and wet spring could be contributing to the worst West Nile virus outbreak since the disease was first detected in the United States in 1999. According to the Centers for Disease Control and Prevention, there have been more cases of the virus so far this year than any year. As of August 14, almost 700 cases had been reported across the nation, including 26 deaths. This year also marks the earliest reported case of West Nile virus in New Jersey. [More]
Two new targets could enhance the body's defenses against West Nile and hepatitis C

Two new targets could enhance the body's defenses against West Nile and hepatitis C

Two new targets have been discovered for antiviral therapies and vaccines strategies that could enhance the body's defenses against such infectious diseases as West Nile and hepatitis C. The targets are within the infection warning system inside living cells. [More]

Low rainfall and high temperatures associated with high numbers of mosquito larvae

Rainfall and temperature affect the abundance of two mosquito species linked to West Nile Virus in storm catch basins in suburban Chicago, two University of Illinois researchers report. [More]
Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

Researcher discovers how West Nile virus breaks through the tough blood-brain barrier to CNS

Mosquitoes are buzzing once again, and with that comes the threat of West Nile virus. Tom Hobman, a researcher with the Li Ka Shing Institute of Virology in the Faculty of Medicine & Dentistry, is making every effort to put an end to this potentially serious infection. [More]

UTMB researchers improve existing experimental vaccine for Rift Valley fever virus

University of Texas Medical Branch researchers have significantly improved an existing experimental vaccine for Rift Valley fever virus, making possible the development of a more effective defense against the dangerous mosquito-borne pathogen. [More]