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Study pinpoints 95 locations in the genome associated with risk of developing PTSD

In posttraumatic stress disorder (PTSD), intrusive thoughts, changes in mood, and other symptoms after exposure to trauma can greatly impact a person's quality of life.

18 Apr 2024

Veteran study reveals medical challenges in men with Klinefelter and Jacobs syndromes

Researchers at the University of Colorado Anschutz Medical Campus and collaborators across the country have conducted the largest and most diverse study of men with extra X or Y chromosomes in the US using a large dataset of military veterans.

29 Mar 2024

Genetic and lifestyle factors linked to brain network aging, study reveals

Research highlights the impact of genetic and lifestyle factors on a brain network particularly sensitive to aging, schizophrenia, and Alzheimer's disease, using data from nearly 40,000 UK Biobank participants to investigate modifiable risk factors and genetic associations.

28 Mar 2024

Study reveals the inner workings of gene mutations linked to ultra-rare syndrome

A team from the University of Ottawa's Faculty of Medicine has completed an exciting new study that reveals the inner workings of gene mutations that result in an ultra-rare syndrome with fewer than 100 reported cases since its first description in the early 1960s.

18 Mar 2024

Females' immune system edges out males but at a cost of higher autoimmune risk

A review article highlights how two X chromosomes in females influence immune system composition and function, leading to faster infection clearance and stronger vaccination responses but also a higher risk of autoimmune diseases.

22 Feb 2024

Mediterranean diet hailed for heart health benefits in women, study finds

Study highlights the Mediterranean diet's cardioprotective benefits for females, emphasizing its role in improving lipid profiles, blood pressure, and reducing cardiovascular disease risks, with a call for more female-focused research.

21 Feb 2024

New study sheds light on sex differences in allergic airway inflammation

Researchers explored how sex hormones and chromosomes influence allergic inflammation and gene expression in four-core genotype (FCG) mice exposed to house dust mites (HDMs).

7 Feb 2024

Xist lncRNA identified as key trigger in female-biased autoimmune diseases

Researchers uncover that the Xist ribonucleoprotein complex, unique to females, is a key driver of sex-biased autoimmunity, offering new insights into autoimmune disorders' higher prevalence in women.

4 Feb 2024

X-chromosome inactivation and its role in autoimmune susceptibility in females

Somewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our own tissues. As many as 4 out of 5 of those people are women.

1 Feb 2024

Unbiased assessment of vamorolone for treating Duchenne muscular dystrophy

The drug vamorolone (Agamree) has been hailed as a promising new drug to treat Duchenne muscular dystrophy (DMD).

25 Jan 2024

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes

Ancient DNA reveals first prehistoric cases of Turner and Jacob's syndromes, with new technique enhancing chromosome analysis

13 Jan 2024

JAK inhibitors and tocilizumab elicit better response rates in VEXAS syndrome

New research at ACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeting, found that JAK inhibitors (JAKi) and tocilizumab elicited better response rates in VEXAS syndrome compared to other targeted therapies.

7 Nov 2023

New drug gets FDA approval for the treatment of common genetic disease in young boys

A new drug developed by professors from the School of Pharmacy and Pharmaceutical Sciences at Binghamton University has received Food and Drug Administration (FDA) approval for the treatment of patients with Duchenne muscular dystrophy (DMD), a common genetic disease that mostly affects young boys.

31 Oct 2023

Researchers identify two main pathways involved in Alzheimer's disease

Dementia, which includes Alzheimer's disease, currently affects around 1.8 million people in Germany. The exact cause has not yet been clarified, but genetic factors play a significant role in the development of the disease.

6 Oct 2023

Rare genetic variants involved in male-pattern hair loss identified

A receding hairline, a total loss of hair from the crown, and ultimately, the classical horseshoe-shaped pattern of baldness: Previous research into male pattern hair loss, also termed androgenetic alopecia, has implicated multiple common genetic variants.

22 Sep 2023

Study explores the role of sex on mRNA and protein levels and its genetic regulation in brain

Researchers investigated the impact of biological sex on protein levels and its genomic control by analyzing 1,277 proteomes of the brain.

4 Sep 2023

Differences in immune responses to IL-6 inhibition therapy between male and female COVID-19 patients

Researchers investigated whether anti‑interleukin 6 monoclonal antibodies were related to heterogenous treatment effects between male and female COVID-19 patients.

24 Aug 2023

First complete sequences of multiple human Y chromosomes shed light on its evolution and biology

Highly challenging to sequence and long overlooked, the human Y chromosome's contributions to health and disease remain largely unknown.

23 Aug 2023

New therapy to mitigate fragile X syndrome may be on the horizon

An antisense therapy developed by Joel D. Richter, PhD, Sneha Shah, PhD, and Jonathan K. Watts, PhD, at UMass Chan Medical School and Elizabeth Berry-Kravis, MD, PhD, at RUSH University Medical Center, restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome.

5 Jul 2023

Unlocking the complete potential of industrial hemp using genomics

Plant biologist Alex Harkess, PhD, and his lab at HudsonAlpha Institute for Biotechnology are on a mission to change the future of food and fiber crops, one flowering plant species at a time.

7 Jun 2023