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Yellow fever virus, a flavivirus, is transmitted to humans through the bite of infected mosquitoes. Illness ranges in severity from a self-limited febrile illness to severe hepatitis and hemorrhagic fever. Yellow fever disease is diagnosed based on symptoms, physical findings, laboratory testing, and the possibility of exposure to infected mosquitoes. There is no specific treatment for yellow fever; care is based on symptoms. Steps to prevent yellow fever include use of insect repellent, protective clothing, and vaccination. Yellow fever occurs in tropical regions of Africa and in parts of South America. Yellow fever is a very rare cause of illness in U.S. travelers. The last epidemic of yellow fever in North America occurred in New Orleans in 1905.
Scientists isolate new multicomponent virus from mosquitoes

Scientists isolate new multicomponent virus from mosquitoes

Scientists have identified a new "multicomponent" virus -- one containing different segments of genetic material in separate particles -- that can infect animals, according to research published today in the journal Cell Host & Microbe. [More]
Cloned Zika virus could be used for development of attenuated vaccine

Cloned Zika virus could be used for development of attenuated vaccine

Stopping the explosive spread of Zika virus - which can lead to birth defects in babies born to infected mothers - depends on genetic insights gleaned through new tools and models. [More]
Geographers map internal migration across three continents to help combat infectious diseases

Geographers map internal migration across three continents to help combat infectious diseases

Geographers at the University of Southampton have completed a large scale data and mapping project to track the flow of internal human migration in low and middle income countries. [More]
Large emergency vaccination campaigns to curb yellow fever outbreak in Angola, Democratic Republic of Congo

Large emergency vaccination campaigns to curb yellow fever outbreak in Angola, Democratic Republic of Congo

One of the largest emergency vaccination campaigns ever attempted in Africa will start in Angola and the Democratic Republic of Congo this week as WHO and partners work to curb a yellow fever outbreak that has killed more than 400 people and sickened thousands more. [More]
New odour-baited traps offer effective and safe solution to fight against malaria mosquito

New odour-baited traps offer effective and safe solution to fight against malaria mosquito

The use of a newly-developed mosquito trap incorporating human odour has resulted in a 70% decline in the population of the most significant malaria mosquito on the Kenyan island of Rusinga. [More]
Scientists modeling new control mechanism to combat Zika-infecting mosquitoes

Scientists modeling new control mechanism to combat Zika-infecting mosquitoes

The images are heartbreaking: thousands of infants born with small, misshapen heads, the result of a rare neurological disorder, called microcephaly, which can cause a myriad of intellectual and developmental disabilities. The culprit? Zika, a mosquito-borne virus that has swept through many parts of South America and more recently surfaced in Florida. [More]
New study provides projections for Zika outbreaks in the Americas through January 2017

New study provides projections for Zika outbreaks in the Americas through January 2017

With the report from Florida Gov. Rick Scott on Monday that 14 people in the state have been infected with the Zika virus most likely through mosquito transmission, the concern about out­breaks in the U.S. has intensified. [More]
Scientists seeking blood donations from people exposed to arboviruses for dengue, Zika vaccine research

Scientists seeking blood donations from people exposed to arboviruses for dengue, Zika vaccine research

Researchers at the University of North Carolina School of Medicine are conducting studies that utilize blood donations from individuals who have been diagnosed with or potentially exposed to mosquito-borne viruses as part of ongoing dengue and Zika research and vaccine development. [More]
WHO supports deployment of mobile lab for fast-tracking diagnosis of yellow fever

WHO supports deployment of mobile lab for fast-tracking diagnosis of yellow fever

“Treating a yellow fever patient is reliant on having the right diagnosis. This is dependent on having the necessary laboratory capacity to quickly identify the disease,” says Dr Pierre Formenty, an expert in haemorrhagic fevers at WHO and Manager of the Emerging Dangerous Pathogens Laboratory Network. [More]
NIAID begins early-stage trial of experimental vaccine for preventing yellow fever virus

NIAID begins early-stage trial of experimental vaccine for preventing yellow fever virus

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has begun an early-stage clinical trial of an investigational vaccine designed to protect against yellow fever virus. [More]
Scientists unveil structure of Zika NS1 protein

Scientists unveil structure of Zika NS1 protein

Researchers have revealed the molecular structure of a protein produced by the Zika virus that is thought to be involved in the virus's reproduction and its interaction with a host's immune system. [More]
Recombinant antigens and antibodies for the Zika virus

Recombinant antigens and antibodies for the Zika virus

Anglo-American life science firm AMSBIO announces a new range of recombinant antigens and antibodies for Zika virus, which are suited for the development of rapid assays and to overcome the problem of cross-reactivity with related viruses. [More]
SLU researchers study investigational vaccine for yellow fever

SLU researchers study investigational vaccine for yellow fever

Saint Louis University's Center for Vaccine Development is studying an investigational vaccine for yellow fever, a potentially deadly disease that is spread by the same mosquito that transmits Zika virus. [More]
WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

WRAIR collaborates with Sanofi Pasteur to develop ZPIV vaccine candidate

The Walter Reed Army Institute of Research announces a Cooperative Research and Development Agreement for the development of a Zika vaccine candidate with Sanofi Pasteur, the vaccines division of Sanofi. [More]
Biosecurity Research Institute takes two-part approach in fighting Zika virus

Biosecurity Research Institute takes two-part approach in fighting Zika virus

Kansas State University is helping the fight against Zika virus through mosquito research. [More]
Wolbachia bacterium can prevent mosquitoes from transmitting Zika virus

Wolbachia bacterium can prevent mosquitoes from transmitting Zika virus

Researchers at the University of Wisconsin-Madison have confirmed that a benign bacterium called Wolbachia pipientis can completely block transmission of Zika virus in Aedes aegypti, the mosquito species responsible for passing the virus to humans. [More]
Two vaccine candidates provide complete protection against ZIKV infection in mice

Two vaccine candidates provide complete protection against ZIKV infection in mice

The rapid development of a safe and effective vaccine to prevent the Zika virus (ZIKV) is a global priority, as infection in pregnant women has been shown to lead to fetal microcephaly and other major birth defects. [More]
Health strategies for families when traveling abroad with kids

Health strategies for families when traveling abroad with kids

Before your family heads to Mexico, Asia or beyond this summer, do a little planning to keep everyone healthy during their journey. Dr. Nava Yeganeh, an assistant professor of pediatric infectious diseases and director of the Pediatric International Travel and Adoption Clinic at Mattel Children's Hospital UCLA, explains three important strategies. [More]
First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

First CRISPR/Cas9 screen helps identify human proteins required for Zika virus replication

Scientists at the University of Massachusetts Medical School have performed the first CRISPR/Cas9 screen to discover human proteins that Zika virus needs for replication. [More]
Fractional dosing approach could be used to control yellow fever outbreaks during vaccine shortages

Fractional dosing approach could be used to control yellow fever outbreaks during vaccine shortages

The yellow fever vaccine given as one fifth of the regular dose could be used to control an outbreak in case of vaccine shortages. [More]
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