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The role of oxidative stress in congenital syndromes

Researchers discuss the role of oxidative stress in genetic conditions.

10 Oct 2022

Microscopy technique enables visualization of unseen nanostructures within cells and tissues

Inside a living cell, proteins and other molecules are often tightly packed together. These dense clusters can be difficult to image because the fluorescent labels used to make them visible can't wedge themselves in between the molecules.

29 Aug 2022

UC Davis research reveals a novel role for how tau functions in healthy nerve cells

In Alzheimer's Disease and other neurodegenerative dementias, proteins that normally play a role in healthy brain tissue turn bad, clumping together to form insoluble plaques and tangles as neurons wither and die.

25 Aug 2022

Changes in brain connections occur very early in Alzheimer's disease

Although a lot is known about brain alterations in symptomatic Alzheimer's disease (AD), less is known about changes in the brain network early in the disease process.

24 Aug 2022

Common viruses may play a role in some cases of Alzheimer's disease

Researchers from Oxford's Institute of Population Ageing, Tufts University and the University of Manchester have discovered that common viruses appear to play a role in some cases of Alzheimer's disease (AD).

3 Aug 2022

Women with a history of hypertensive disorders of pregnancy more likely to develop dementia

Hypertensive disorders of pregnancy (HDP) — conditions of high blood pressure including chronic/gestational hypertension and preeclampsia — have been strongly linked to heart disease in later life, but, before today, little research has connected these disorders with cognition.

3 Aug 2022

Microvascular disease and Alzheimer's associated with more white matter damage, more inflammation

Disease of the microscopic blood vessels that feed the white matter of our brain is associated with worse cognitive function and memory deficits in individuals with Alzheimer's, scientists report.

2 Aug 2022

Experts release appropriate use recommendations for Alzheimer’s disease blood biomarkers

Alzheimer’s disease blood biomarkers (BBMs) may revolutionize the diagnosis of Alzheimer’s in the future, but are not yet ready for widespread use, according to a newly-published article by leading international clinicians and researchers convened by the Alzheimer’s Association.

31 Jul 2022

Study shows the link between common viruses and onset of Alzheimer’s disease

Alzheimer's disease can begin almost imperceptibly, often masquerading in the early months or years as forgetfulness that is common in older age. What causes the disease remains largely a mystery.

29 Jul 2022

Age-related increases in brain inflammation may link Alzheimer's disease risk with sleep disturbance

A multisite research team from the University of California, Irvine, the University of Wisconsin–Madison and Wake Forest University has discovered that brain inflammation may link Alzheimer's disease risk with sleep disturbance, which may aid early detection and prevention efforts by identifying novel treatment targets at preclinical stages.

13 Jul 2022

New non-invasive treatment for patients suffering from treatment-resistant depression and dementia

A joint research team from the LKS Faculty of Medicine, The University of Hong Kong (HKUMed) and City University of Hong Kong (CityU) has discovered that the electrical stimulation of the eye surface can alleviate depression-like symptoms and improve cognitive function in animal models.

8 Jul 2022

Study evaluates diagnostic performance of two blood-based biomarkers specific to Alzheimer's disease

A simple blood test to diagnose Alzheimer's disease, perhaps even years before symptoms appear, is an exciting possibility, but a new study shows that much more research is needed before these blood tests are routinely used in the clinical diagnostic setting.

26 May 2022

Scientists discover a potential new method of active immunization to prevent Alzheimer's disease

During experiments in animal models, researchers at the University of Kansas have discovered a possible new approach to immunization against Alzheimer's disease (AD).

4 May 2022

New Alzheimer’s disease hypothesis could open up diagnosis or treatment possibilities

Alzheimer's Disease could be caused by damage to a protective barrier in the body that allows fatty substances to build up in the brain, newly published research argues.

8 Apr 2022

New project launched to explore how GI microbiota may contribute to neurodegeneration

Alzheimer's disease (AD) is a type of dementia that affects memory, thinking and behavior. According to the Alzheimer's Association, an estimated 6.2 million Americans are living with this progressive neurologic disorder, and it is the sixth-leading cause of death in the U.S.

31 Mar 2022

University of Kentucky begins world’s first clinical trial for LATE

The motivation driving the work of Pete Nelson, M.D., Ph.D., is personal. His grandmother, Sylvia Becker, died with Alzheimer's disease, and he says his mother then grew terrified of developing the disease.

17 Mar 2022

Blood test shows promise to identify Alzheimer's changes in the brain before symptom onset

The University of Kentucky's Sanders-Brown Center on Aging has been around for nearly half a century. In that time, they have built an international reputation for best-in-class research into a disease that kills more people every year than breast and prostate cancer combined – Alzheimer's disease.

10 Mar 2022