Frontotemporal Dementia News and Research RSS Feed - Frontotemporal Dementia News and Research

Common gene mutation may cause brain damage associated with ALS and FTD

Common gene mutation may cause brain damage associated with ALS and FTD

Johns Hopkins researchers say they have discovered some of the first steps in how a very common gene mutation causes the brain damage associated with both amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). [More]
Scientists reveal how a common gene mutation in ALS and FTD disrupts normal cell function

Scientists reveal how a common gene mutation in ALS and FTD disrupts normal cell function

Researchers have determined how the most common gene mutation in amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) disrupts normal cell function, providing insight likely to advance efforts to develop targeted therapies for these brain diseases. [More]
Others consider our moral traits, not memory, to be core component of our identity

Others consider our moral traits, not memory, to be core component of our identity

We may view our memory as being essential to who we are, but new findings suggest that others consider our moral traits to be the core component of our identity. Data collected from family members of patients suffering from neurodegenerative disease showed that it was changes in moral behavior, not memory loss, that caused loved ones to say that the patient wasn't "the same person" anymore. [More]
Johns Hopkins researchers discover role of TDP-43 protein in autopsy brain cells of patients with ALS

Johns Hopkins researchers discover role of TDP-43 protein in autopsy brain cells of patients with ALS

Autopsies of nearly every patient with the lethal neurodegenerative disorder amyotrophic lateral sclerosis (ALS), and many with frontotemporal dementia (FTD), show pathologists telltale clumps of a protein called TDP-43. Now, working with mouse and human cells, Johns Hopkins researchers report they have discovered the normal role of TDP-43 in cells and why its abnormal accumulation may cause disease. [More]
Alzheimer's Association recognizes four scientists with Lifetime Achievement Awards at AAIC 2015

Alzheimer's Association recognizes four scientists with Lifetime Achievement Awards at AAIC 2015

The Alzheimer's Association recognizes four leading scientists for their contributions to advancing Alzheimer's disease and dementia research. The awards were presented during the opening session at the Alzheimer's Association International Conference 2015 in Washington, D.C. [More]
U of T researchers discover new details about key gene involved in ALS

U of T researchers discover new details about key gene involved in ALS

A University of Toronto research team has discovered new details about a key gene involved in ALS, perhaps humanity's most puzzling, intractable disease. [More]
Early neuronal lysosomal dysfunction could help predict AD

Early neuronal lysosomal dysfunction could help predict AD

Blood levels of altered lysosomal proteins may help detect preclinical Alzheimer’s disease, researchers report. [More]
Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

Specialized brain proteins may be detected in the blood samples of individuals with Alzheimer's disease

Specialized brain proteins that are involved in the removal of damaged nerve cell materials may be detected in the blood of people who were diagnosed with mild cognitive impairment or dementia due to Alzheimer's disease. [More]
People with cognitive impairment have altered responses to pain

People with cognitive impairment have altered responses to pain

People with dementia and other forms of cognitive impairment (CI) have altered responses to pain, with many conditions associated with increased pain sensitivity, concludes a research review in PAIN, the official publication of the International Association for the Study of Pain. [More]
Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Mayo Clinic scientists create mouse model of ALS, FTD caused by mutations in C9ORF72 gene

Scientists at Mayo Clinic, Jacksonville, Florida created a novel mouse that exhibits the symptoms and neurodegeneration associated with the most common genetic forms of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS, Lou Gehrig's disease), both of which are caused by a mutation in the a gene called C9ORF72. [More]

Studies refine amyloid imaging role in dementia

Two meta-analyses published in JAMA help to define the role of amyloid imaging in dementia. [More]
Available research does not support link between chronic traumatic encephalopathy and sports

Available research does not support link between chronic traumatic encephalopathy and sports

Available research does not support the contention that athletes are uniquely at risk of chronic traumatic encephalopathy (CTE) or other neurodegenerative disorders, according to a review in the June issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. [More]
Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Proteomics helps identify previously unrecognized proteins and pathways in nerve regeneration

Using proteomics techniques to study injured optic nerves, researchers at Boston Children's Hospital have identified previously unrecognized proteins and pathways involved in nerve regeneration. Adding back one of these proteins--the oncogene c-myc--they achieved unprecedented optic nerve regeneration in mice when combined with two other known strategies. [More]
High-skill jobs may increase survival for people with frontotemporal dementia

High-skill jobs may increase survival for people with frontotemporal dementia

Doctors, lawyers and other "high level" professionals may have a built-in survival edge if they're diagnosed with the disease frontotemporal dementia (FTD), according to new research from the Perelman School of Medicine at the University of Pennsylvania. [More]
Study: Demanding jobs raise survival chances in frontotemporal dementia

Study: Demanding jobs raise survival chances in frontotemporal dementia

People with more demanding jobs may live longer after developing the disease frontotemporal dementia than people with less skilled jobs, according to a new study published in the April 22, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. [More]
Biologists identify new mechanisms linked to progression of aggressive form of dementia

Biologists identify new mechanisms linked to progression of aggressive form of dementia

Research by biologists at the University of York has identified new mechanisms potentially driving progression of an aggressive form of dementia. [More]
Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

Study shows amyloid formation may link type 2 diabetes and Alzheimer disease

The pathological process amyloidosis, in which misfolded proteins (amyloids) form insoluble fibril deposits, occurs in many diseases, including Alzheimer disease (AD) and type 2 diabetes mellitus (T2D). [More]
Three leading research funders join forces to support brain disease research

Three leading research funders join forces to support brain disease research

Three leading research funders from the UK and North America have joined forces to launch a new global initiative called MEND or, MEchanisms of cellular death in NeuroDegeneration, with a fund of $1.25 million USD (£820,000/$1.56CDN) for targeted research into brain diseases that cause dementia, such as Alzheimer's. [More]
People who carry longevity gene variant have larger brain region

People who carry longevity gene variant have larger brain region

People who carry a variant of a gene that is associated with longevity also have larger volumes in a front part of the brain involved in planning and decision-making, according to researchers at UC San Francisco. [More]
UAB research suggests potential therapeutic target for patients with frontotemporal dementia

UAB research suggests potential therapeutic target for patients with frontotemporal dementia

Drugs that boost the function of a specific type of neurotransmitter receptor may provide benefit to patients with the second most common type of dementia, according to research by scientists at the University of Alabama at Birmingham published today in the Journal of Neuroscience. [More]
Advertisement
Advertisement