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CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

CD4/CD8 ratio biomarker could help identify HIV-infected individuals at risk for heart disease

The ratio of CD4 to CD8 T cells in the blood-a marker of immune system health and associated with mortality risk in the general population-is an independent predictor of coronary heart disease in HIV-infected patients, according to a new study published in AIDS Research and Human Retroviruses, a peer-reviewed journal from Mary Ann Liebert, Inc., publishers. [More]
New gene therapy shows promising results for treating neurodegenerative disorders

New gene therapy shows promising results for treating neurodegenerative disorders

A new gene therapy approach designed to replace the enzyme that is deficient in patients with the inherited neurodegenerative disorders Tay-Sachs and Sandhoff diseases successfully delivered the therapeutic gene to the brains of treated mice, restored enzyme function, and extended survival by about 2.5-fold. [More]
FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

FDA approves new injection to improve blood sugar levels in adults with type 2 diabetes

The U.S. Food and Drug Administration approved Adlyxin (lixisenatide), a once-daily injection to improve glycemic control (blood sugar levels), along with diet and exercise, in adults with type 2 diabetes. [More]
Lifestyle modification programs to prevent diabetes improve cardio-metabolic profiles

Lifestyle modification programs to prevent diabetes improve cardio-metabolic profiles

A new study by researchers at Emory's Rollins School of Public Health and the Centers for Disease Control and Prevention shows that lifestyle modification programs modeled on diabetes prevention programs trials not only achieved weight reduction, but also additional metabolic benefits -specifically, reductions in blood sugar, blood pressure, and cholesterol levels. [More]
Levels of peptide hormone adropin linked to carbohydrate intake

Levels of peptide hormone adropin linked to carbohydrate intake

In research featured in the August edition of Obesity, Saint Louis University investigator Andrew Butler, Ph.D., and his team report that levels of the peptide hormone adropin vary based on carbohydrate consumption and appear to be linked to lipid metabolism. [More]
Groundbreaking research opens door for prevention of cardiac fibrosis

Groundbreaking research opens door for prevention of cardiac fibrosis

Groundbreaking research from the University of Alberta and McGill University has opened the door towards the future prevention of cardiac fibrosis—a condition leading to heart failure for which there is currently no treatment. [More]
Women who start menstruation, menopause later in life have increased odds of living to 90-years-old

Women who start menstruation, menopause later in life have increased odds of living to 90-years-old

The number of women living to age 90 in the United States has increased significantly in the past century. [More]
Testing lung health online: an interview with Professor Stephen Holgate

Testing lung health online: an interview with Professor Stephen Holgate

In our latest report – The Battle for Breath – the impact of lung disease in the UK, figures suggest that 1 in 5 (around 12.7 million) have been diagnosed with a lung condition in the UK. If you’re over the age of 70, this rises to 1 in 3. [More]
Online behavioural intervention provides long-term, sustainable ways to lose weight

Online behavioural intervention provides long-term, sustainable ways to lose weight

New research, led by the University of Southampton, has found that an online behavioural counselling tool is effective at helping people lose weight. [More]
Maternal placental syndromes increase short-term risk of developing cardiovascular disease

Maternal placental syndromes increase short-term risk of developing cardiovascular disease

The short-term risk of developing cardiovascular disease following a first pregnancy is higher for women experiencing placental syndromes and a preterm birth or an infant born smaller than the usual size, a University of South Florida study reports. [More]
Early and late menopause linked to increased risk of developing type 2 diabetes

Early and late menopause linked to increased risk of developing type 2 diabetes

Women who begin menopause before age 46 or after 55 have an increased risk of developing type 2 diabetes, according to a study of more than 124,000 women enrolled in the Women's Health Initiative, a large national trial aimed at preventing disease in postmenopausal women. [More]
New insights into RNA-protein interactions may lead to cure for heart disease

New insights into RNA-protein interactions may lead to cure for heart disease

Research led by The Australian National University has uncovered new insights into how the human genome gets through the daily grind with the help of RNA-binding proteins, in a discovery which could ultimately lead to a cure for heart disease. [More]
Community-based lifestyle programs can also improve health-related quality of life

Community-based lifestyle programs can also improve health-related quality of life

The value of a healthy lifestyle isn't reflected only in the numbers on the scale or the blood pressure cuff. [More]
Exposure to infections in early life not linked to higher mortality risk during adulthood

Exposure to infections in early life not linked to higher mortality risk during adulthood

A new biological study by the University of Stirling has found that exposure to infections in early life does not have long-lasting consequences for later-life survival and reproduction. [More]
Sleep researchers call for new diagnostic criteria to treat OSA in pregnant women

Sleep researchers call for new diagnostic criteria to treat OSA in pregnant women

Recent studies reveal that approximately one quarter of pregnant women may suffer from Obstructive Sleep Apnea (OSA), the recurrent cessation or limitation of normal breathing during sleep. [More]
Study highlights need to deepen health reforms in China

Study highlights need to deepen health reforms in China

China needs to further reform its health system with a number of critical steps to meet the growing health needs of the population and further control spending increases, despite impressive achievements in healthcare reform and rapid progress toward universal health coverage. [More]
Shared lifestyle and environment may contribute to risk of common diseases in families, study shows

Shared lifestyle and environment may contribute to risk of common diseases in families, study shows

Family history of disease may be as much the result of shared lifestyle and surroundings as inherited genes, research has shown. [More]
Breakthrough research shows cellular stress could be key to variety of birth defects

Breakthrough research shows cellular stress could be key to variety of birth defects

For the first time, scientists believe they've discovered a cause of multiple types of birth defects triggered by environmental stresses. [More]
Children born with CHD more likely to develop type 2 diabetes in adulthood

Children born with CHD more likely to develop type 2 diabetes in adulthood

Children born with heart disease have an increased risk of developing type 2 diabetes after age 30, according to a new study. [More]
Biochemists design genetic poison pill to thwart coxsackievirus B3

Biochemists design genetic poison pill to thwart coxsackievirus B3

It has a funny name - coxsackievirus - but there's nothing funny about how this tiny germ and its close relatives sicken their hosts. [More]
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