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Study reveals protective role of C3 protein in insulin-producing cells

Although there are many differences between type 1 diabetes and type 2 diabetes, there are also similarities, such as inflammation of the insulin-producing cells.

21 Mar 2024

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Gastric cancer ranks among the most widespread diseases in Asian populations, with South Koreans experiencing the third-highest incidence globally in 2020, as reported by the International Agency for Research on Cancer.

21 Mar 2024

Lactate's role in driving cancer cachexia uncovered

Study highlights the significant role of lactate in promoting cancer cachexia via activation of the adipose-specific G-protein-coupled receptor 81 (GPR81), suggesting new therapeutic targets for this condition.

20 Mar 2024

Astrocyte immune memory in multiple sclerosis pathology revealed

Immunological memory -; the ability to respond to a previously encountered antigen, or foreign substance, with greater speed and intensity on re-exposure is a hallmark of adaptive immunity.

20 Mar 2024

Unique bacteria colonize the gut shortly after birth and make serotonin to educate gut immune cells

A recent study revealed that neonatal gut bacteria produce serotonin and down-regulate monoamine oxidase A (MOA) to limit serotonin breakdown, thereby promoting immune tolerance.

20 Mar 2024

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Scientists from the National University of Singapore (NUS) have discovered that the evasion of apoptosis is a key driver of drug resistance in patients with relapsed acute myeloid leukaemia (AML), a type of aggressive blood cancer.

19 Mar 2024

Unlocking quinoa's power: Beyond nutrition to drug development

Existing data on the bioactive constituents of quinoa and their health benefits.

18 Mar 2024

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Therapeutic cancer vaccines are a form of immunotherapy in the making that could not only destroy cancer cells in patients, but keep a cancer from coming back and spreading.

15 Mar 2024

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

The therapeutic potential of oleuropein (OLE) and hydroxytyrosol (HT) from olive oil.

15 Mar 2024

Mapping the heart's cellular blueprint: New insights into cardiac structure and disease repair

Researchers unveil the complex cellular architecture of the heart using advanced RNA sequencing and imaging techniques, shedding light on the intricate organization of heart cells and their developmental pathways.

14 Mar 2024

Boosting curcumin's absorption and effectiveness for disease prevention and therapy

The potential of nano-formulations to boost the bioavailability and bioactivity of curcumin.

12 Mar 2024

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

A team of investigators from the UCLA Health Jonsson Comprehensive Cancer and the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute was awarded a $3.2 million grant from the National Institutes of Health to identify new ways to prevent and overcome treatment resistance to targeted therapy in patients with all sub-types of cutaneous melanoma, an aggressive form of skin cancer.

11 Mar 2024

Breakthrough in CRISPR delivery promises safer gene editing

Recent research in PNAS highlights advancements in non-viral, cell-specific delivery methods for CRISPR-Cas systems, emphasizing their potential to enhance research and gene therapy applications by minimizing risks associated with off-target effects and improving targeted delivery.

7 Mar 2024

Innovative BioSUM device detects post-surgical leaks via pH changes

A new device tested in pigs enables monitoring and early detection of pH changes in deep tissues due to post-operative leaks following gastrointestinal surgery.

7 Mar 2024

Researchers discover promising approach to combat multidrug-resistant Salmonella infections

A new collaborative study discloses the discovery and application of a new therapeutic strategy to target the multidrug-resistant bacterium Salmonella enterica in vivo, with promising results. The results were published in Scientific Reports.

7 Mar 2024

Study reveals nerve changes linked to pain and urinary frequency in recurrent UTI sufferers

How sensory nerve sprouting and mast cell activity, driven by nerve growth factor (NGF), contribute to persistent bladder pain and dysfunction in recurrent urinary tract infection (rUTI) cases.

7 Mar 2024

Study uncovers unexpected level of complexity hidden within neutrophils

In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population of short-lived immune cells.

6 Mar 2024

in vivo News and Research

Study reveals protective role of C3 protein in insulin-producing cells

Advancing precision personalized medicine for gastric cancer with 3D bioprinting

Lactate's role in driving cancer cachexia uncovered

Astrocyte immune memory in multiple sclerosis pathology revealed

Unique bacteria colonize the gut shortly after birth and make serotonin to educate gut immune cells

NUS study reveals key mechanisms behind drug resistance in relapsed acute myeloid leukemia

Unlocking quinoa's power: Beyond nutrition to drug development

DNA origami vaccine DoriVac paves way for personalized cancer immunotherapy

Exploring olive oil compounds oleuropein and hydroxytyrosol as potential treatments for neuroblastoma

Mapping the heart's cellular blueprint: New insights into cardiac structure and disease repair

Boosting curcumin's absorption and effectiveness for disease prevention and therapy

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

Breakthrough in CRISPR delivery promises safer gene editing

Innovative BioSUM device detects post-surgical leaks via pH changes

Researchers discover promising approach to combat multidrug-resistant Salmonella infections

Study reveals nerve changes linked to pain and urinary frequency in recurrent UTI sufferers

Study uncovers unexpected level of complexity hidden within neutrophils

Key brain cells linked to repetitive behaviors in psychiatric diseases

Revolutionary tool for tracking physical interactions between different cells

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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