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Study reveals nerve changes linked to pain and urinary frequency in recurrent UTI sufferers

How sensory nerve sprouting and mast cell activity, driven by nerve growth factor (NGF), contribute to persistent bladder pain and dysfunction in recurrent urinary tract infection (rUTI) cases.

7 Mar 2024

Study uncovers unexpected level of complexity hidden within neutrophils

In a study published in Cell on March 5, Prof. Zhang Xiaoming at the Shanghai Institute of Immunity and Infection (SIII) of the Chinese Academy of Sciences and Profs. Gao Qiang, Fan Jia and Yang Li at Fudan University have uncovered an unexpected level of complexity hidden within neutrophils, which were previously thought to be a relatively uniform population of short-lived immune cells.

6 Mar 2024

Key brain cells linked to repetitive behaviors in psychiatric diseases

Crym-expressing astrocytes in the striatum have been identified as key regulators of behaviors often seen in neuropsychiatric diseases, opening up new avenues for targeted therapies.

6 Mar 2024

Revolutionary tool for tracking physical interactions between different cells

One of the fundamental goals of basic biology is understanding how diverse cell types work in concert to form tissues, organs, and organ systems.

6 Mar 2024

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Cervical cancer is among the most common malignancies affecting women worldwide. In 2020 alone, approximately 600,000 women were diagnosed with this disease, and over 314,000 died from it.

5 Mar 2024

Novel screening system reveals sperm cell development and health at the molecular level

A novel screening system developed at Kyoto University enables researchers to investigate sperm cell development and health at the molecular level.

5 Mar 2024

New catheter-based device images heart disease plaques with unprecedented detail

Researchers have developed a new catheter-based device that combines two powerful optical techniques to image the dangerous plaques that can build up inside the arteries that supply blood to the heart.

5 Mar 2024

DNA aptamer-based sensors can accurately detect trace amounts of fentanyl, heroin, and cocaine

Researchers from North Carolina State University have developed a new generation of high-performance DNA aptamers and highly accurate drug sensors for cocaine and other opioids.

5 Mar 2024

New method simplifies production of limb progenitor cells from fibroblasts

In a collaborative study, researchers from Kyushu University and Harvard Medical School have identified proteins that can turn or "reprogram" fibroblasts -; the most commonly found cells in skin and connective tissue -; into cells with similar properties to limb progenitor cells.

4 Mar 2024

New method revolutionizes in vivo brain imaging in awake mice

The human brain has billions of neurons. Working together, they enable higher-order brain functions such as cognition and complex behaviors.

4 Mar 2024

The impact of quinoa bioactive compounds on gut health

Researchers review the beneficial impacts of quinoa and its bioactive compounds, particularly its effects on intestinal microflora.

4 Mar 2024

Gut bacteria diversity linked to body weight, athletes show healthier profiles

Systematic review reveals gut microbiome variations correlate with body composition changes across lifespan, highlighting differences between obese individuals and athletes.

29 Feb 2024

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Researchers developed an engineered transcriptional repressor that durably silences the Pcsk9 gene in mice, reducing cholesterol levels for up to a year with a single treatment, showcasing a potential breakthrough in genetic disorder treatments without the risks of DNA mutation.

29 Feb 2024

in vivo News and Research

Study reveals nerve changes linked to pain and urinary frequency in recurrent UTI sufferers

Study uncovers unexpected level of complexity hidden within neutrophils

Key brain cells linked to repetitive behaviors in psychiatric diseases

Revolutionary tool for tracking physical interactions between different cells

Scientists develop robust iPSC-derived rejuvenated T lymphocytes for cervical cancer treatment

Novel screening system reveals sperm cell development and health at the molecular level

New catheter-based device images heart disease plaques with unprecedented detail

DNA aptamer-based sensors can accurately detect trace amounts of fentanyl, heroin, and cocaine

New method simplifies production of limb progenitor cells from fibroblasts

New method revolutionizes in vivo brain imaging in awake mice

The impact of quinoa bioactive compounds on gut health

Gut bacteria diversity linked to body weight, athletes show healthier profiles

Breakthrough gene silencing method slashes cholesterol for a year in mice, no DNA damage

Interdisciplinary project aims to decode human kinome in brain function and disease

Breakthrough CRISPR technique unlocks insights about cancer immunology

New lung cell atlas unveils pathways to lung adenocarcinoma development

Genetic studies shed light on hypertension risk but fall short of revealing new treatments

Optibrium launches a metabolism prediction software platform tailored to DMPK scientists

Neuropsychiatric symptoms can be potential predictors of Alzheimer's development

Globe artichokes: A rich source of dietary fiber and phenolic antioxidants

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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