microRNA News and Research

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In genetics, microRNAs (miRNA) are single-stranded RNA molecules of 21-23 nucleotides in length, which regulate gene expression. miRNAs are encoded by genes from whose DNA they are transcribed but miRNAs are not translated into protein (i.e. they are non-coding RNAs); instead each primary transcript (a pri-miRNA) is processed into a short stem-loop structure called a pre-miRNA and finally into a functional miRNA. Mature miRNA molecules are partially complementary to one or more messenger RNA (mRNA) molecules, and their main function is to down-regulate gene expression.
BWH researchers use specific microRNA to identify, alter makeup of glioblastoma subtypes

BWH researchers use specific microRNA to identify, alter makeup of glioblastoma subtypes

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

New single probe method provides PCR-free detection of microRNA linked to liver toxicity

Could a blood test predict how cancer spreads in children?

Could a blood test predict how cancer spreads in children?

Lack of 'editing' in microRNAs can potentially drive brain cancers

Lack of 'editing' in microRNAs can potentially drive brain cancers

Tiny microRNA could act as protective mechanism to reduce risk of epileptic seizures, say scientists

Tiny microRNA could act as protective mechanism to reduce risk of epileptic seizures, say scientists

Scientists discover unexpected mechanism behind chronic nerve pain

Scientists discover unexpected mechanism behind chronic nerve pain

Researchers identify small RNA molecule that promotes deadly forms of breast cancer

Researchers identify small RNA molecule that promotes deadly forms of breast cancer

Light-inducible antimiRs could improve wound healing in diabetes patients

Light-inducible antimiRs could improve wound healing in diabetes patients

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

LMU scientists uncover molecular mechanism that links tumor hypoxia and metastasis

Researchers identify microRNA biomarker linked to incidence of atrial fibrillation

Researchers identify microRNA biomarker linked to incidence of atrial fibrillation

Researchers discover that microRNA can prevent excessive intestinal inflammation

Researchers discover that microRNA can prevent excessive intestinal inflammation

MicroRNA-210 stabilizes deposits in carotid artery to prevent stroke risk

MicroRNA-210 stabilizes deposits in carotid artery to prevent stroke risk

Researchers uncover new potential target for treating spinal muscular atrophy

Researchers uncover new potential target for treating spinal muscular atrophy

Researchers identify appetite-suppression mechanism in flies

Researchers identify appetite-suppression mechanism in flies

Treatment with microRNA re-insulates ravaged nerves, restores limb mobility in mouse models of MS

Treatment with microRNA re-insulates ravaged nerves, restores limb mobility in mouse models of MS

Data protection in medical research: Computer scientists crack anonymity of genetic information

Data protection in medical research: Computer scientists crack anonymity of genetic information

New markers linked to recurrence of erratic heartbeats in some patients after ablation therapy

New markers linked to recurrence of erratic heartbeats in some patients after ablation therapy

TSRI researchers develop new drug candidates to target prostate and triple negative breast cancers

TSRI researchers develop new drug candidates to target prostate and triple negative breast cancers

Researchers develop innovative nanobiodevice that enables rapid detection of cancer biomarker

Researchers develop innovative nanobiodevice that enables rapid detection of cancer biomarker

UAlberta scientists use nanomachines for improved disease detection and drug delivery

UAlberta scientists use nanomachines for improved disease detection and drug delivery