10. November 2009 03:17
Oncologists have had their hands tied because more than half of all human cancers have mutations that disable a protein called p53. As a critical anti-cancer watchdog, p53 masterminds several cancer-fighting operations within cells. When cells lose p53, tumors grow aggressively and often cannot be treated.
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27. October 2009 08:57
Champions Biotechnology, Inc., an oncology drug development company with a predictive preclinical platform aimed at accelerating the development and enhancing the value of oncology drugs, has established an exclusive licensing agreement with Ramot at Tel Aviv University Ltd., Tel Aviv University's wholly owned technology transfer company.
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17. July 2009 03:22
Estrogen can halt stroke damage by inactivating a tumor-suppressing protein known to prevent many cancers, Medical College of Georgia researchers say.
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12. July 2009 19:28
The death toll from three of the UK's most common cancers has dropped to its lowest level for almost 40 years* - according to new figures released by Cancer Research UK.
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Posted in: Medical Research News
Tags: Bowel Cancer, Brain Cancer, Breast Cancer, Cancer, Carboplatin, Cisplatin, Colorectal Cancer, Herceptin (Trastuzumab), Lung Cancer, p53 Protein, Prostate Cancer, Tamoxifen, Temozolomide
23. June 2009 06:31
Researchers at Children's Hospital Boston have isolated a potent inhibitor of tumor metastasis made by tumor cells, one that could potentially be harnessed as a cancer treatment.
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4. June 2009 19:49
At the ends of chromosome are special pieces of DNA called telomeres. Think of it as the little tip that caps off a shoelace. The telomeres send signals to the cells to let them know it's the end point, not a break that should be repaired.
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1. June 2009 18:13
University of Michigan scientists have found that a deficiency in a key tumor suppressor gene in the brain leads to the most common type of adult brain cancer. The study, conducted in mice that mimic human cancer, points the way to more effective future treatments and a way to screen for the disease early.
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20. April 2009 23:08
Dr. Esther Chang describes the most recent developments in human trials of the first systemic, non-viral, tumor-targeted, nanoparticle method designed to restore normal gene function to tumor cells while completely bypassing normal tissue April 21 at an American Association of Anatomists (AAA) scientific session at Experimental Biology 2009 in New Orleans.
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Posted in: Medical Research News
Tags: Antibody, Breast Cancer, Cancer, Chemotherapy, Gene Therapy, Genetics, Head and Neck Cancer, Melanoma, Nanoparticle, p53 Protein, Radiotherapy
20. April 2009 23:01
Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore "wild type" function to p53 in a variety of tumor cells.
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20. April 2009 08:11
In what is believed to be the largest study of its kind in the US, researchers have found that almost 26 percent of women studied who have breast cancer have mutations in a gene important in controlling cell growth and death, and that patients with mutations in this gene - known as p53 - had poorer outcomes including a significantly increased risk of death from the cancer.
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13. April 2009 21:37
Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1.
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6. April 2009 21:25
AVEO Pharmaceuticals, Inc. has announced findings from its novel human-in-mouse (HIM) cancer model system, in which AVEO successfully created invasive human tumors from primary human breast tissue that develop over time in mice and mimic human tumor behaviors and response.
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1. April 2009 22:05
Researchers at UT Southwestern Medical Center have identified a new biological indicator that may help identify which brain-cancer patients have the most aggressive forms of the disease.
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Posted in: Medical Research News
Tags: Brain, Brain Tumor, Cancer, Chemotherapy, DNA, Genetics, Glioblastoma, Glioblastoma Multiforme, Neurology, Oncology, Otolaryngology, p53 Protein, Pathology, Pharmacology, Radiology
1. April 2009 21:13
Researchers have identified a possible genetic cause for increased risk for a more advanced form of colorectal cancer in blacks that leads to shorter survival, according to data published in Clinical Cancer Research , a journal of the American Association for Cancer Research.
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1. April 2009 10:36
Being able to accurately predict how a given cancer will respond to chemotherapy would spare patients with non-responsive tumors the burden of undergoing toxic and ultimately unhelpful treatment.
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Posted in: Medical Research News
Tags: Acute Myeloid Leukaemia, Bone, Bone Marrow, Cancer, Chemotherapy, Chromosome, Gene Expression, Genetics, Myeloid Leukemia, Oncogene, p53 Protein
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