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Longitudinal multi-omics monitoring paves the way for early pancreatic cancer diagnosis

A new case report published in the peer-reviewed OMICS: A Journal of Integrative Biology describes how longitudinal multi-omics monitoring (LMOM) helped to detect a precancerous pancreatic tumor and led to a successful surgical intervention.

23 Apr 2024

Study uncovers aspirin's role in colorectal cancer development and progression

Long-term daily use of aspirin can help to prevent the development and progression of colorectal cancer, but the mechanisms involved have been unclear.

22 Apr 2024

Exploring serine and glycine metabolism in hepatocellular carcinoma

Targeted therapy and immunotherapy have emerged as treatment options for hepatocellular carcinoma (HCC) in recent years. The significance of serine and glycine metabolism in various cancers is widely acknowledged.

22 Apr 2024

Liver cells effectively serve as immune checkpoint regulating anti-cancer immunity

Liver inflammation, a common side-effect of cancers elsewhere in the body, has long been associated with worse cancer outcomes and more recently associated with poor response to immunotherapy.

22 Apr 2024

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

The role of neighborhood-level disparities in determining shorter breast cancer-specific survival.

22 Apr 2024

Engineered peptides show promise in cancer immunotherapy

In a new study published today in Nature Biomedical Engineering, researchers at The University of Texas MD Anderson Cancer Center have designed a new method for developing immunotherapy drugs using engineered peptides to elicit a natural immune response inside the body.

22 Apr 2024

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

Study evaluates the role of cruciferous vegetables and their bioactive components in mitigating inflammatory bowel disease through in vitro, in vivo, and preliminary clinical investigations, suggesting a promising therapeutic avenue.

21 Apr 2024

New AI tool 'TORCH' successfully identifies cancer origins in unknown primary cases

A deep-learning approach for tumor origin differentiation using cytological histology.

19 Apr 2024

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

With more than 200 types of cancer and every cancer individually unique, ongoing efforts to develop precision oncology treatments remain daunting.

18 Apr 2024

New trials show promise for immune checkpoint blockers in early-stage lung cancer

A dendritic cell (DC) vaccine targeting patient-specific neoantigens to patients with resected non-small cell lung cancer (NSCLC).

18 Apr 2024

Breakthrough imaging method enhances precision in prostate cancer treatment

A novel SPECT/CT acquisition method can accurately detect radiopharmaceutical biodistribution in a convenient manner for prostate cancer patients, opening the door for more personalized treatment.

17 Apr 2024

New research pinpoints key pathways in prostate cancer's vulnerability to ferroptosis

Review examines the role of ferroptosis, an iron-dependent form of cell death, in prostate cancer, exploring its underlying molecular mechanisms and potential for targeted therapeutic strategies.

17 Apr 2024

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

For the first time in fifty years, results from a phase 3 randomized, placebo-controlled trial have shown an overall survival benefit from an adjuvant therapy in patients with kidney cancer.

17 Apr 2024

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

In an ambitious new study, a research team that included scientists from Yale set out to uncover potential treatments for patients with rare neuroendocrine tumors of the cervix (NETc) by understanding the molecular basis of the aggressive disease.

17 Apr 2024

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, reports a study in the April issue of The Journal of Urology, an Official Journal of the American Urological Association.

17 Apr 2024

Triple-negative breast cancer patients with high immune cell levels have lower relapse risk after surgery

Women with triple-negative breast cancer, and high levels of immune cells in the tumors, have a lower relapse risk after surgery, even without chemotherapy.

17 Apr 2024

Exploring the versatile roles of tissue macrophages beyond immune defense

The role of resident tissue macrophages (RTMs) in homeostasis and disease.

17 Apr 2024

New genetic insights: Sugary beverages linked to higher risk of atrial fibrillation

The associations between the intake of pure fruit juices (PFJ) and sugar-sweetened beverages (SSBs) with cardiovascular disease (CVD).

17 Apr 2024

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Vaccine-based therapeutics for age-related disorders.

17 Apr 2024

Targeted nanoparticle delivery of FZD4 decreases lung tumor growth and metastasis

A recent breakthrough study from the lab of Tanya Kalin, MD, PhD, professor of Child Health and Internal Medicine at the University of Arizona College of Medicine – Phoenix, has shown potential to improve therapeutic outcomes for patients suffering from lung cancers.

16 Apr 2024

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Tumor News and Research

Longitudinal multi-omics monitoring paves the way for early pancreatic cancer diagnosis

Study uncovers aspirin's role in colorectal cancer development and progression

Exploring serine and glycine metabolism in hepatocellular carcinoma

Liver cells effectively serve as immune checkpoint regulating anti-cancer immunity

Do neighborhood-level disparities in breast cancer–specific survival remain after accounting for individual, tumor, and treatment characteristics?

Engineered peptides show promise in cancer immunotherapy

Cruciferous vegetables may offer new hope for inflammatory bowel disease management

New AI tool 'TORCH' successfully identifies cancer origins in unknown primary cases

First-of-its-kind AI tool predicts patient response to cancer drugs at single-cell resolution

New trials show promise for immune checkpoint blockers in early-stage lung cancer

Breakthrough imaging method enhances precision in prostate cancer treatment

New research pinpoints key pathways in prostate cancer's vulnerability to ferroptosis

Phase 3 trial shows overall survival benefit from adjuvant therapy in kidney cancer patients

Study findings better define the genetic landscape of neuroendocrine tumors of the cervix

Combined chemohormonal therapy for locally advanced prostate cancer offers extended control of PSA levels

Triple-negative breast cancer patients with high immune cell levels have lower relapse risk after surgery

Exploring the versatile roles of tissue macrophages beyond immune defense

New genetic insights: Sugary beverages linked to higher risk of atrial fibrillation

Vaccines targeting chronic diseases show promise in combatting age-related conditions

Targeted nanoparticle delivery of FZD4 decreases lung tumor growth and metastasis

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut

From Puberty to Menopause: Clue’s CEO, Audrey Tsang on the Power of Femtech

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