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Natural compound could reduce risk of developing triple-negative breast cancer metastasis

Natural compound could reduce risk of developing triple-negative breast cancer metastasis

More than 100 women die from breast cancer every day in the United States. Triple-negative breast cancers, which comprise 15 to 20 percent of all breast tumors, are a particularly deadly type of breast disease that often metastasize to distant sites. [More]
Tulane researchers discover cancer-causing role of protein thought to be tumor suppressor

Tulane researchers discover cancer-causing role of protein thought to be tumor suppressor

Tulane University researchers have discovered that the protein PHLDB3, thought to be a potential tumor suppressor, actually allows cancer cells to thrive in pancreatic, prostate, colon, breast, lung, and other common cancers. [More]
Researchers investigate influence of surrounding tissue on formation and growth of tumor cells

Researchers investigate influence of surrounding tissue on formation and growth of tumor cells

Malignant melanoma is the fastest-growing type of cancer and the most fatal skin disease. [More]
Novel noninvasive method precisely tweaks brain activity in rats using ultrasound pulses

Novel noninvasive method precisely tweaks brain activity in rats using ultrasound pulses

Biomedical engineers at Johns Hopkins report they have worked out a noninvasive way to release and deliver concentrated amounts of a drug to the brain of rats in a temporary, localized manner using ultrasound. [More]
Researchers uncover mechanism of resistance used by triple negative breast cancer

Researchers uncover mechanism of resistance used by triple negative breast cancer

Breast cancer cells are evasive, finding ways to bypass drugs designed to stop their unchecked growth. [More]
Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Chemotherapy prior to surgery could improve prognosis in African-American breast cancer patients

Administering chemotherapy to African-American breast cancer patients prior to surgery could improve their prognosis and survival rates from the disease, according to a new study. [More]
A quarter of men could safely avoid prostate biopsy if MRI is used

A quarter of men could safely avoid prostate biopsy if MRI is used

Performing an MRI scan of men with suspected prostate cancer could spare a quarter of men from having to undergo prostate biopsy, according to a study published in The Lancet. [More]
Precision medicine advances diagnosis and treatment of children with brain tumors

Precision medicine advances diagnosis and treatment of children with brain tumors

Precision medicine - in which diagnosis and treatments are keyed to the genetic susceptibilities of individual cancers - has advanced to the point where it can now impact the care of a majority of children with brain tumors, a new study by investigators at Dana-Farber/Boston Children's Cancer and Blood Disorders Center suggests. [More]
Salk scientists show how microenvironment signals encourage growth of pancreatic tumors

Salk scientists show how microenvironment signals encourage growth of pancreatic tumors

Just as an invasive weed might need nutrient-rich soil and water to grow, many cancers rely on the right surroundings in the body to thrive. [More]
Study provides scientific insight into metastatic patterns of EGFR mutated NSCLCs

Study provides scientific insight into metastatic patterns of EGFR mutated NSCLCs

The discovery of several different subtypes of Non Small Cell Lung Cancer (NSCLC), the most frequent form of lung cancer, has been a major breakthrough in the fight against the leading cause of cancer-related death worldwide. [More]
MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

MGH-developed CTC-iChip with digital PCR assay improves detection of early-stage liver cancer

Use of an advanced form of the commonly used polymerase chain reaction (PCR) method to analyze circulating tumor cells (CTCs) may greatly increase the ability to diagnose early-stage cancer, increasing the likelihood of successful treatment. [More]
Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Mayo Clinic researchers identify genetic promoter that drives lung cancer formation

Researchers at Mayo Clinic have identified a genetic promoter of cancer that drives a major form of lung cancer. [More]
RIT research explores impact of shear stress on cells moving through blood vessels

RIT research explores impact of shear stress on cells moving through blood vessels

How do cells and protein molecules respond to stress as they travel through blood vessels? Could resulting changes to these biological components impact how diseases are spread? [More]
Northwestern Medicine investigators to lead clinical trial for people with rare cancers

Northwestern Medicine investigators to lead clinical trial for people with rare cancers

A novel national trial for people with no established alternative to treat their rare cancers is being co-led by Northwestern Medicine investigators, who helped conceive of and develop the project. [More]
ICLIO white paper spotlights top-level concerns in delivering immunotherapies for cancer

ICLIO white paper spotlights top-level concerns in delivering immunotherapies for cancer

While momentum around immunotherapies for cancer continues to build, the high cost of these therapies places them at the center of debate about how best to define and measure value in cancer care. [More]
Researchers uncover structure of cancer cell receptor protein that paves way for drug development

Researchers uncover structure of cancer cell receptor protein that paves way for drug development

A team of researchers from Case Western Reserve University School of Medicine has helped uncover the elusive structure of a cancer cell receptor protein that can be leveraged to fight disease progression. [More]
‘Collateral lethality’ may create new therapeutic options for several cancers

‘Collateral lethality’ may create new therapeutic options for several cancers

Cancer cells often delete genes that normally suppress tumor formation. These deletions also may extend to neighboring genes, an event known as "collateral lethality," which may create new options for development of therapies for several cancers. [More]
Researcher awarded $1.8 million grant to explore how chronic stress impacts cancer development

Researcher awarded $1.8 million grant to explore how chronic stress impacts cancer development

A five-year, $1.8 million grant (R01CA203965) from the National Cancer Institute awarded to Rutgers Cancer Institute of New Jersey resident research member Wenwei Hu, PhD, will support research to further elucidate the mechanisms behind the most frequently mutated gene in human tumors - p53. [More]
Protein involved in pancreatic cancer development plays more complicated role, study finds

Protein involved in pancreatic cancer development plays more complicated role, study finds

A protein thought to fuel pancreatic cancer development plays a much more complicated role, a new study finds. [More]
TGen scientists identify potent inhibitory compound for treatment against glioblastoma

TGen scientists identify potent inhibitory compound for treatment against glioblastoma

A study led by scientists at the Translational Genomics Research Institute has identified "a potent inhibitory compound" in the elusive hunt for an improved treatment against glioblastoma, the most common and deadly type of adult brain cancer. [More]
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