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Researchers identify how precise control of inflammation could lead to bone repair

Researchers identify how precise control of inflammation could lead to bone repair

In their mission to design new biomaterials that promote tissue regeneration, Drexel University researchers have identified how inflammation, when precisely controlled, is crucial to bone repair. [More]
DRG International to present Aldosterone ELISA Kit at 2016 AACC

DRG International to present Aldosterone ELISA Kit at 2016 AACC

DRG International, a leading international medical diagnostic company, will showcase its DRG Aldosterone ELISA Kit at the 2016 AACC in Philadelphia, Pennsylvania on August 02-04. [More]
Roche announces FDA approval of  new VENTANA PD-L1 assay

Roche announces FDA approval of new VENTANA PD-L1 assay

Roche today announced approval of the VENTANA PD-L1 (SP142) Assay by the US Food and Drug Administration as a complementary diagnostic to provide PD-L1 status on patients who are considering treatment with the FDA approved Roche immunotherapy TECENTRIQâ„¢ (atezolizumab) for metastatic urothelial cancer (mUC). [More]
Study clarifies role of KLF12 in CRC tumor growth

Study clarifies role of KLF12 in CRC tumor growth

Results of preclinical studies by MUSC investigators reported in the July 2016 issue of PLOS One, demonstrate for the first time that the transcription factor KLF12 promotes CRC cell growth, in part, by activating EGR1. Furthermore, data demonstrate that KLF12 and EGR1 levels synergistically correlate with poor CRC prognoses. [More]
Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Triple-combination therapy patch shrinks tumors, prevents recurrence in colon cancer mice model

Investigators at Brigham and Women's Hospital have developed a hydrogel patch that can adhere to tumors in a preclinical model of colon cancer, delivering a local, combination treatment as the elastic gel breaks down over time. [More]
Research could help clinicians identify patients who may benefit from targeted therapy for liver cancer

Research could help clinicians identify patients who may benefit from targeted therapy for liver cancer

New research from Roswell Park Cancer Institute offers clinicians treating patients with advanced liver cancer a way of determining which patients may benefit most from the targeted therapy sorafenib. [More]
Microswimmer robots could help deliver medicine and perform surgery inside the body

Microswimmer robots could help deliver medicine and perform surgery inside the body

Drexel University researchers, led by MinJun Kim, PhD, a professor in the College of Engineering, have successfully pulled off a feat that both sci-fi fans and Michael Phelps could appreciate. [More]
T-cell technology could be used to treat ovarian tumors with no adverse effects

T-cell technology could be used to treat ovarian tumors with no adverse effects

With only incremental improvements in ovarian cancer survival over the last 40 years, there is a clear need for new treatment options with long-lasting results. Many researchers have turned toward the development of immunotherapies that direct T-cells to selectively eliminate ovarian tumor cells, but an appropriate therapeutic target for ovarian cancers has remained elusive. [More]
Scientists identify novel way to target lung cancer through KRAS gene

Scientists identify novel way to target lung cancer through KRAS gene

UT Southwestern Medical Center researchers have identified a new way to target lung cancer through the KRAS gene, one of the most commonly mutated genes in human cancer and one researchers have so far had difficulty targeting successfully. [More]
Study reports sampling method used for new breast cancer tests may need to be refined

Study reports sampling method used for new breast cancer tests may need to be refined

Not only is breast cancer more than one disease, but a single breast cancer tumor can vary within itself, a finding that University of Pittsburgh Cancer Institute researchers discovered has the potential to lead to very different patient treatment plans depending on the tumor sample and diagnostic testing used. [More]
Researchers develop new approach for visualizing oxygen in tissue

Researchers develop new approach for visualizing oxygen in tissue

Learning how to look inside a body without having to cut it open is still an important part of medical research. One of the great challenges in imaging remains the visualization of oxygen in tissue. [More]
ZMYND8 protein can suppress metastasis-linked genes in prostate cancer

ZMYND8 protein can suppress metastasis-linked genes in prostate cancer

Although it reads like European license plate number, a protein known as ZMYND8 has demonstrated its ability to block metastasis-linked genes in prostate cancer, according to a study at The University of Texas MD Anderson Cancer Center. [More]
Researchers find promising new therapy for both pediatric and adult cancers

Researchers find promising new therapy for both pediatric and adult cancers

A study conducted at Nationwide Children's Hospital has found that a new chemotherapy is effective against both pediatric and adult cancers, and that it allows other chemotherapies to more readily reach their targets. [More]
Researchers develop tiny 3-D tissue models to study how ovarian cancer develops in women

Researchers develop tiny 3-D tissue models to study how ovarian cancer develops in women

With a unique approach that draws on 3-D printing technologies, a team of University of Wisconsin-Madison researchers is developing new tools for understanding how ovarian cancer develops in women. [More]
New combination treatment improves overall survival in patients with malignant melanoma

New combination treatment improves overall survival in patients with malignant melanoma

Among patients with melanoma, those who received both ipilimumab (Yervoy) and local peripheral treatments such as radiotherapy or electrochemotherapy had significantly prolonged overall survival compared with those who received only ipilimumab, according to a retrospective clinical study. [More]
FDA-approved nerve ablation procedure may offer new treatment option for low back pain

FDA-approved nerve ablation procedure may offer new treatment option for low back pain

It's the most common reason people go to their doctors - back pain. According to the National Institutes of Health, 80 percent of adults will experience low back pain some time in their lives. [More]
Genetic profiling offers new avenues for treatment of cancer, study finds

Genetic profiling offers new avenues for treatment of cancer, study finds

Genetic profiling of cancer tumors provides new avenues for treatment of the disease, according to a study conducted by Sanford Health and recognized by the American Society of Clinical Oncology. [More]
Focused therapy may be effective, less toxic way to treat brain tumors

Focused therapy may be effective, less toxic way to treat brain tumors

Physicians from Carolinas HealthCare System's Neurosciences Institute and Levine Cancer Institute are among the authors of a study that was accepted for publication by the Journal of the American Medical Association. The study, released on July 26, 2016, shows that patients with the most common form of brain tumor can be treated in an effective and substantially less toxic way by omitting a widely used portion of radiation therapy. [More]
Researchers find genetic variability in frozen vials of cells purchased from same cell bank

Researchers find genetic variability in frozen vials of cells purchased from same cell bank

In a surprise finding, researchers working with breast cancer cells purchased at the same time from the same cell bank discovered that the cells responded differently to chemicals, even though the researchers had not detected any difference when they tested them for authenticity at the time of purchase. [More]
Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Liquid biopsies hold potential for detecting NSCLC EGFR mutations, predicting cancer recurrence

Three manuscripts published in the recent issue of the Journal of Thoracic Oncology, the official journal of the International Association for the Study of Lung Cancer, explored the versatility of liquid biopsies by identifying EGFR mutations using circulating tumor DNA (ctDNA) in urine and plasma and examining circulating tumor cells (CTCs) in plasma to predict the risk of lung cancer recurrence after surgical resection. [More]
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