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Melatonin appears to suppress growth of breast cancer stem cells

Melatonin appears to suppress growth of breast cancer stem cells

Melatonin, a hormone produced in the human brain, appears to suppress the growth of breast cancer tumors. [More]
TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

TMDU researchers inject gelatin-based gel carrying protein/peptide drugs to trigger bone augmentation

The part of the jawbone containing tooth sockets is known as alveolar bone, and its loss over time or following dental disease may ultimately result in tooth loss. [More]
NIH researchers discover rare, lethal inflammatory disease that affects young children

NIH researchers discover rare, lethal inflammatory disease that affects young children

National Institutes of Health researchers have discovered a rare and sometimes lethal inflammatory disease - otulipenia - that primarily affects young children. They have also identified anti-inflammatory treatments that ease some of the patients' symptoms: fever, skin rashes, diarrhea, joint pain and overall failure to grow or thrive. [More]
Tel Aviv University researchers unravel how melanoma spreads to distant organs

Tel Aviv University researchers unravel how melanoma spreads to distant organs

In a landmark discovery, researchers at Tel Aviv University have unraveled the metastatic mechanism of melanoma, the most aggressive of all skin cancers. [More]
Study examines psychological impact of tumor gene testing in subset of NCI-MATCH patients

Study examines psychological impact of tumor gene testing in subset of NCI-MATCH patients

The ECOG-ACRIN Cancer Research Group has received federal approval to add a quality-of-life research study, COMmunication and Education in Tumor Profiling (EAQ152) or 'COMET' to the NCI-MATCH (EAY131) trial, already underway. [More]
Researchers identify tantalizing target in fight against aggressive form of lung cancer

Researchers identify tantalizing target in fight against aggressive form of lung cancer

Researchers at the University of Virginia School of Medicine have discovered a flaw in the armor of the most aggressive form of lung cancer, a weakness that doctors may be able to exploit to slow or even stop the disease. [More]
Study highlights racial/ethnic disparities in genomic sequencing

Study highlights racial/ethnic disparities in genomic sequencing

As scientists learn more about which genetic mutations are driving different types of cancer, they're targeting treatments to small numbers of patients with the potential for big payoffs in improved outcomes. [More]
Fruit fly models may help scientists understand underlying mechanism of HPV-induced cancer

Fruit fly models may help scientists understand underlying mechanism of HPV-induced cancer

Human papillomavirus (HPV) is one of the most common sexually transmitted infections in the United States and has been identified as a primary cause of cervical cancer in women. [More]
Colorectal tumors present epigenetic heterogeneity, study finds

Colorectal tumors present epigenetic heterogeneity, study finds

A new study led by Dr. Manel Esteller, Director of the Epigenetics and Cancer Biology Program of Bellvitge Biomedical Research Institute, ICREA researcher and Professor of Genetics at University of Barcelona discovers that colorectal tumors present epigenetic heterogeneity that relates to the clinical course of the disease. [More]
Novel marine natural product appears to reduce pancreatic tumor size

Novel marine natural product appears to reduce pancreatic tumor size

Scientists at Florida Atlantic University's Harbor Branch Oceanographic Institute found that a deep-water marine sponge collected off of Fort Lauderdale's coast contains leiodermatolide, a natural product that has the ability to inhibit the growth of cancer cells as well as block cancer cells from dividing using extremely low concentrations of the compound. [More]
New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene

New NIST Standard Reference Material helps ensure accurate measurements of HER2 breast cancer gene

A new measurement standard developed by the National Institute of Standards of Technology has been used successfully by the Frederick National Laboratory for Cancer Research to check the performance of next-generation DNA-sequencing technologies for evaluating gene variations associated with an increased risk of breast cancer. [More]
Research findings open avenues for creating new classes of anticancer drugs

Research findings open avenues for creating new classes of anticancer drugs

A new study at Los Alamos National Laboratory and in collaboration with Stanford Synchrotron Radiation Lightsource greatly improves scientists' understanding of the element actinium. The insights could support innovation in creating new classes of anticancer drugs. [More]
Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

Maintaining proper oxygen supply in tumors could be key factor to stop progression of cancer

The lack of oxygen in tumor cells changes the cells' gene expression, thereby contributing to the growth of cancer. [More]
Research article outlines utilization of calixarenes in biocatalysis and cancer therapy

Research article outlines utilization of calixarenes in biocatalysis and cancer therapy

Calixarenes bear a fascinating class of macrocycles that have served broadly in molecular recognition and supramolecular chemistry. [More]
Digital risk calculator provides faster, reliable estimation of GIST recurrence

Digital risk calculator provides faster, reliable estimation of GIST recurrence

GIST (Gastrointestinal Stromal Tumor) is an uncommon type of sarcoma found in the tissues supporting the digestive system (stomach and intestines). [More]
New study shows female urologists perform more surgeries on women than male counterparts

New study shows female urologists perform more surgeries on women than male counterparts

Although female certified urologists are still a minority within the specialty, they perform many more procedures on women than their male colleagues, who perform more procedures on men than their female colleagues. [More]
Study shows microRNA molecule prevents cancer cells from responding to chemotherapy treatment

Study shows microRNA molecule prevents cancer cells from responding to chemotherapy treatment

Annually about 2000 Danish patients with colorectal cancer are treated with chemotherapy. Today, a range of different chemotherapeutic regimens are available. However, deciding which regimen to use is not easy. [More]
Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows

Computers could be more accurate than pathologists in assessing lung cancer tissues, study shows

Computers can be trained to be more accurate than pathologists in assessing slides of lung cancer tissues, according to a new study by researchers at the Stanford University School of Medicine. [More]
Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Study shows leptomeningeal metastases more prevalent in NSCLC patients with EGFR mutations

Leptomeningeal metastases (LM), a devastating complication and predictor of poor survival in lung cancer patients, was found to be more prevalent in non-small cell lung cancer (NSCLC) patients with epidermal growth factor receptor (EGFR) mutations. [More]
German scientists develop new approach to prevent GvHD after bone marrow transplants

German scientists develop new approach to prevent GvHD after bone marrow transplants

Scientists in Germany have developed a new approach that may prevent leukemia and lymphoma patients from developing graft-versus-host disease (GvHD) after therapeutic bone marrow transplants. [More]
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