Archived Medical News Stories

RSSArchived Drug Trial News Stories - 2012

Date Title Comments Rating
2012-12-29 Aeterna Zentaris reaches SPA agreement with FDA for AEZS-108 Phase 3 trial in endometrial cancer 0 None
2012-12-27 Juxtapid receives FDA approval for treatment of rare cholesterol disorder 0 None
2012-12-25 AMAG seeks FDA sNDA approval for Feraheme Injection 0 None
2012-12-21 BCPR, Orexigen partner to accelerate patient enrollment for Contrave obesity Light Study 0 None
2012-12-21 Halozyme grants Pfizer worldwide license to develop products combining Enhanze with biologics 0 None
2012-12-21 Gene therapy shows promise for severe coronary artery disease 0 None
2012-12-21 OncoMed commences dosing in OMP-52M51 Phase 1 clinical trial for hematologic cancers 0 None
2012-12-21 Cubist seeks FDA sNDA approval for ENTEREG to accelerate GI recovery 0 None
2012-12-21 Pergamum’s DPK-060 Phase II trial on acute external otitis meets primary end-point 0 None
2012-12-21 UCLA study assesses prevalence of various types of study partners in Alzheimer's trials 0 None
2012-12-20 Merck’s TREDAPTIVE clinical study on high-risk CVD patients does not meet primary endpoint 0 None
2012-12-20 Antibiotic amoxicillin ineffective for treating cough according to European trial 0 None
2012-12-20 Lancet reports on global efforts to develop malaria vaccine 0 None
2012-12-20 Positive top-line results from Idera’s IMO-3100 Phase 2a trial on plaque psoriasis 0 None
2012-12-20 Top-line results from Medivir's simeprevir phase III trials on genotype 1 HCV infection 0 None
2012-12-19 Infectex initiates enrollment in SQ109 Phase IIb-III trial for MDR-TB 0 None
2012-12-19 EMD Serono's L-BLP25 Phase III NSCLC trial does not meet primary endpoint 0 None
2012-12-19 HAL Allergy completes enrollment in SUBLIVAC FIX Phleum pratense Phase II trial 0 None
2012-12-18 Pharmalink commences Nefecon Phase IIb study in primary IgA nephropathy 1 None
2012-12-18 e-Therapeutics’ ETS2101 cancer trials on track 0 None
2012-12-18 IRMA, Population Council and MTN release Rectal Revolution video project 0 None
2012-12-17 GTx achieves enrollment goal for pivotal Phase III clinical studies of enobosarm 0 None
2012-12-16 Cognitive test used in Alzheimer's drug trials is flawed: Study 0 None
2012-12-15 AcelRx announces top-line data from Sufentanil NanoTab PCA System Phase 3 trial 0 None
2012-12-15 Ibrutinib continues to show unprecedented results in patients with mantle cell lymphoma 0 None
2012-12-15 Cempra commences CEM-102 Phase 2 trial in prosthetic joint infections 0 None
2012-12-14 High-dose vitamin D can reduce risk of respiratory tract infections 0 None
2012-12-14 ETA receptor antagonism reduces novel cardiovascular risk factors in patients with CKD 0 None
2012-12-13 NovaDigm announces data from NDV-3 vaccine Phase 1 study on Candida and Staph infections 0 None
2012-12-13 Top-line results from AstraZeneca’s fostamatinib Phase IIb monotherapy study on RA 0 None
2012-12-13 Positive data from Oncolytics’ REOLYSIN Phase III combination study on head and neck cancers 0 None
2012-12-13 Medivir commences cohort 2 simeprevir and sofosbuvir phase II combination trial in HCV GT1 0 None
2012-12-13 Eli Lilly provides update on solanezumab Phase 3 clinical study for mild Alzheimer's 0 None
2012-12-13 Bumetanide could treat children with severe autism or Asperger's syndrome 2 5
2012-12-13 AZD6765 briefly improves treatment-resistant patients' depression symptoms in minutes 0 None
2012-12-13 Dantrolene may help combat Duchenne muscular dystrophy in boys 1 None
2012-12-13 Interim results from Inspiration’s OBI-1 and IB1001 hemophilia clinical study 0 None
2012-12-13 Unigene announces results from oral PTH Phase 2 study on osteoporosis 0 None
2012-12-12 Industry sponsored clinical trials present a more favourable picture of reported findings 0 None
2012-12-12 Inotuzumab ozogamicin selectively destroys malignant cells responsible for ALL in weekly dosing 0 None
2012-12-12 AstraZeneca, Case Western Reserve initiate AZD5847 Phase 2a trial in TB 0 None
2012-12-12 Acetazolamide plus autoCPAP may reduce insomnia and control sleep apnea at high altitudes 0 None
2012-12-12 Tiotropium benefits patients with chronic obstructive pulmonary disease 0 None
2012-12-12 Final data from Aeterna Zentaris’ perifosine plus sorafenib Phase 2 study on lymphomas 0 None
2012-12-12 Astellas, FibroGen commence FG-4592/ASP1517 Phase 3 clinical program in CKD anemia 0 None
2012-12-12 Clinical trial to examine AstraZeneca experimental drug against pulmonary tuberculosis 0 None
2012-12-11 Top-line results from Durata Therapeutics’ dalbavancin Phase 3 study on ABSSSI 0 None
2012-12-11 Astellas, Ambit announce results from quizartinib Phase 2 study on acute myeloid leukemia 0 None
2012-12-11 Studies examine current treatment standards for patients with clotting disorders 0 None
2012-12-11 Pomalidomide safe and effective in treating multiple myeloma 0 5
2012-12-11 Ibrutinib highly active and well tolerated in patients with chronic lymphocytic leukemia 1 None
2012-12-11 Tacrolimus plus sirolimus not better than standard regimen in preventing GVHD 0 None
2012-12-11 Combination of ibrutinib and rituximab shows promise against chronic lymphocytic leukemia 0 None
2012-12-11 uniQure commences acute intermittent porphyria Phase I clinical trial 0 None
2012-12-11 Quizartinib shows promise against acute myeloid leukemia in Phase II trial 0 None
2012-12-11 AMAG presents new data from two ferumoxytol phase III trials on IDA at ASH annual meeting 0 None
2012-12-11 Intensified chemotherapy can reduce risk of relapse in pediatric patients with B-ALL 0 None
2012-12-11 Ligand commences PG-free melphalan pivotal trial in multiple myeloma 0 None
2012-12-11 Metformin therapy improves BMI and fasting glucose levels in obese children 0 None
2012-12-11 Merrimack announces results from MM-302 Phase I trial on advanced HER2 positive breast cancer 0 2.5
2012-12-11 ImmunoGen to present IMGN901 clinical data on multiple myeloma at 54th ASH annual meeting 0 None
2012-12-11 Celgene announces results from REVLIMID plus VIDAZA phase II study on AML 0 None
2012-12-11 Preliminary results from Boehringer Ingelheim’s volasertib Phase II study on AML 0 None
2012-12-11 Infinity announces new data from IPI-145 Phase 1 trial on advanced hematologic malignancies 0 None
2012-12-10 Boehringer Ingelheim to commence volasertib plus LDAC Phase III study for AML 0 None
2012-12-10 Results from eribulin and capecitabine phase III comparison trial on metastatic breast cancer 0 None
2012-12-10 Ipsen, Active Biotech complete enrollment in tasquinimod Phase III trial for prostate cancer 0 None
2012-12-10 New survival results from Genentech’s Perjeta Phase III combination study on HER2-positive mBC 0 None
2012-12-10 Ibrutinib may effectively combat chronic lymphocytic leukemia 0 None
2012-12-10 Mesupron could extend progression-free survival for metastatic breast cancer patients 0 None
2012-12-10 Sanofi announces new data from SAR302503 Phase II trial on myelofibrosis 0 None
2012-12-10 Iroko’s submicron indomethacin Phase 3 study on post-surgical acute pain meets primary endpoint 0 None
2012-12-09 Celldex announces final results from CDX-011 Phase 2b study on GPNMB-expressing breast cancer 0 None
2012-12-07 Results of Halaven Phase III study in metastatic breast cancer presented at 2012 CTRC-AACR SABCS 0 None
2012-12-07 Novel antidepressant targets brain receptors responsible for learning and memory 0 None
2012-12-06 FDA designates two of Cubist’s Phase 3 antibiotic candidates 0 None
2012-12-06 Naurex reports positive results from GLYX-13 Phase IIa trial on depression 0 None
2012-12-06 Bio-Path to initiate BP-100-1.01 Phase I trial for treatment of two types of breast cancer 0 None
2012-12-06 Scancell announces preliminary results from Part 1 of ImmunoBody vaccine Phase 1/2 MM trial 0 5
2012-12-06 Fexinidazole enters Phase II/III clinical study to treat sleeping sickness 0 None
2012-12-06 Combination of PD-991 and letrozole improves survival in patients with HER2- breast cancer 0 None
2012-12-06 Poorer cancer patients less likely to have access to experimental drug trials 0 None
2012-12-06 Tenofovir DF safe and effective in treating adolescents with HBV 0 None
2012-12-06 University of Florida initiates enrollment in SPI-1005 Phase II trial for sensorineural hearing loss 0 None
2012-12-05 Sickle cell disease trial completes phase 3 patient enrollment 0 None
2012-12-05 RXi commences RXI-109 Phase 1 study for management of surgical scars and keloids 0 None
2012-12-05 New data from AstraZeneca's FASLODEX studies on breast cancer to be presented at SABSC 0 None
2012-12-05 NOXXON commences NOX-H94 Phase IIa trial to treat anemia of chronic disease 0 None
2012-12-05 Cabozantinib effectively treats prostate cancer spread to bones 0 None
2012-12-04 Virginia Women's Center to participate in new HPV and cervical cancer vaccine clinical trial 0 None
2012-12-04 Very high dose prednisolone reasonable alternative to ACTH for children with infantile spasms 0 4
2012-12-04 Antidepressants in normal dosage may positively impact mood and seizure frequency 0 None
2012-12-04 Certain patients with prostate cancer may benefit from Provenge clinical trial 1 None
2012-12-03 Enzalutamide shows promise in treating triple-negative and estrogen-positive breast cancer 0 None
2012-12-03 Merck commences MK-8931 Phase II/III trial in Alzheimer's 0 None
2012-12-03 NeuroVive announce results from CicloMulsion Phase I trial on cardiac reperfusion injury 0 None
2012-11-30 Clinical trial shows effectiveness of ponatinib in patients with leukemia and lymphoma 0 None
2012-11-30 Combination of chemotherapy and selumetinib shows promise against NSCLC 0 None
2012-11-30 GM1 ganglioside effectively treats patients with Parkinson's disease 5 5
2012-11-30 Novartis to highlight key data from extensive oncology portfolio at SABCS and ASH meeting 0 None
2012-11-30 Boehringer Ingelheim announces new data from volasertib Phase I/II leukemia study 0 None
2012-11-30 Aduro completes enrollment in CRS-207 and GVAX pancreas cancer vaccine Phase 2 trial 0 None
2012-11-30 Epizyme to present data from DOT1L and EZH2 inhibitor programs at 54th ASH annual meeting 0 None
2012-11-29 InSite Vision completes enrollment in BromSite Phase 3 trial for reduction of pain, inflammation 0 None
2012-11-29 Ponatinib thwarts T315I gene mutation in chronic myeloid leukemia 0 5
2012-11-29 University of Cincinnati to lead Belatacept Early Steroid withdrawal Trial 0 None
2012-11-29 Suvorexant may bring help for people with insomnia 0 1
2012-11-29 Tadalafil may offer therapeutic strategy in patients with Becker muscular dystrophy 0 None
2012-11-29 UCB to sponsor key sets of VIMPAT C-V data at 66th American Epilepsy Society annual meeting 0 None
2012-11-29 CEL-SCI's Multikine cancer drug receives key Japanese patent 0 None
2012-11-29 NovImmune commences NI-0101 Phase I clinical trial in arthritis 0 None
2012-11-28 Combination of mixed amphetamine salts and topiramate shows promise for cocaine dependence 0 None
2012-11-28 Bayer completes recruitment of first cohort for BAY 86-6150 Phase II/III study in hemophilia 0 None
2012-11-28 Merrimack’s MM-302 Phase I results and MM-DX-929 preclinical data to be presented at SABCS 0 None
2012-11-28 Enrollment begins in Elan’s ELND005 Phase 2 trial for agitation/aggression associated with AD 0 None
2012-11-27 Amarantus demonstrates excellent diffusion profile of MANF in the striatum of rat brains 0 None
2012-11-27 FDA clears Avaxia’s AVX-470 IND for treatment of ulcerative colitis 0 5
2012-11-27 Liver disease therapies: an interview with Eric Halioua, CEO of Promethera Biosciences 0 None
2012-11-26 Accera commences clinical efficacy trial of AC-1204 for mild-to-moderate Alzheimer's disease 0 None
2012-11-26 FDA grants Seattle Genetics orphan drug designation for ADCETRIS to treat mycosis fungoides 0 None
2012-11-26 Interim GALAXY Phase 2b lung cancer study results to be presented at APLCC 2012 0 None
2012-11-26 Cancer-killing viruses found safe but less effective than expected 0 None
2012-11-26 Apitope announces completion of recruitment in ATX-MS-1467 Phase I trial for MS 1 None
2012-11-23 Lymphopenia driven diseases and the orphan drug industry: an interview with Damian Marron, CEO of Cytheris 0 None
2012-11-23 Allon Files Preliminary Shelf Prospectus 0 None
2012-11-22 Belgian FAMHP authorizes C3BS Phase III Congestive Heart failure Cardiopoietic Regenerative Therapy trial 0 None
2012-11-22 Bowel cancer and GIST patients could benefit from novel oral drug 0 None
2012-11-22 University of Liverpool to conduct immunoglobulin clinical study for complex regional pain syndrome 0 None
2012-11-22 Somnogen induces sleep in patients with primary hypersomnia 0 None
2012-11-22 Citicoline not superior to placebo in treating traumatic brain injury 0 None
2012-11-21 Regorafenib able to control resistant gastrointestinal stromal tumor 0 4.3
2012-11-21 Rituximab may help patients with aPL-related clinical problems 0 None
2012-11-21 UMDNJ, Proteonomix commence screening of patients with ESLD for use in UMK-121 clinical trial 0 None
2012-11-21 Scientists extract recent drug trials to tackle Alzheimer's earlier than ever before 0 None
2012-11-21 NeuroDerm initiates enrollment in ND0612 Phase I trial for Parkinson's 0 None
2012-11-20 Top-line results from Pfizer's pregabalin CR formulation Phase 3 study on fibromyalgia 0 None
2012-11-20 Combination of perifosine and temsirolimus shows promise against malignant glioma 0 None
2012-11-19 Diffusion Pharmaceuticals completes trans sodium crocetinate Phase I trial on glioblastoma 0 None
2012-11-19 Positive results from Genentech Avastin plus temozolomide Phase III study on glioblastoma 1 3
2012-11-17 Interim results from RTS,S vaccine on-going phase III trial on malaria 0 None
2012-11-17 Combination of Abraxane and gemcitabine improves survival of patients with pancreatic cancer 0 None
2012-11-16 Denosumab associated with improved overall survival in NSCLC patients 0 None
2012-11-16 Positive results from POZEN’s PA8140-102 Phase 1 bioavailability study 0 None
2012-11-15 RXi announces pharmacokinetic results from RXI-109 Phase 1 study in healthy subjects 0 None
2012-11-15 Enrollment complete in Exact Sciences DeeP-C screening trial for colorectal cancer 0 None
2012-11-15 Researchers describe structure of active site core of topoisomerase II alpha anti-cancer drug target 0 None
2012-11-15 Positive preliminary results from ImmunoPulse Phase II trial in metastatic melanoma 0 None
2012-11-15 Trastuzumab increases risk of heart failure in older women with breast cancer 0 None
2012-11-15 Paxvax PXVX0200 cholera vaccine demonstrates safety and immunogenicity in Phase 1 clinical trial 0 None
2012-11-15 ALN RNAi therapeutic program represents novel approach for treatment of AAT deficiency 0 None
2012-11-14 Blog examines RTS,S malaria vaccine trial results 0 None
2012-11-14 Tiltan Pharma initiates enrollment in TL-118 Phase 2 trial for metastatic pancreatic cancer 0 None
2012-11-13 IDMC reviews data from Nanobiotix’s NBTXR3 Phase I study on advanced soft tissue sarcoma 0 None
2012-11-13 Abbott releases details on phase 3 hepatitis C registrational program 0 None
2012-11-09 RTS,S vaccine candidate can help protect African infants against malaria 0 None
2012-11-09 Omeros to present results from first pivotal Phase 3 trial of OMS302 at AAO annual meeting 0 None
2012-11-09 Immunomic Therapeutics initiates JRC-LAMP-vax vaccine Phase I trial in Sugi allergy 0 None
2012-11-09 Positive results from Palatin’s bremelanotide Phase 2B trial on female sexual dysfunction 0 None
2012-11-08 Plexxikon updates Zelboraf Phase 1 data on BRAF V600E mutation-positive melanoma 0 None
2012-11-08 Patient recruitment complete for immatics IMA901 Phase 3 trial for renal cell carcinoma 0 None
2012-11-08 FDA grants Albireo's A4250 orphan-drug designation for treatment of PFIC and PBC 0 None
2012-11-08 BioCryst completes planned interim analysis of peramivir Phase 3 trial for serious influenza 0 None
2012-11-08 Stapled Peptide oncology drug candidate exhibits robust efficacy in xenograft cancer models 0 None
2012-11-07 Duration of ibuprofen use may reduce risk of bladder cancer in northern New England patients 0 None
2012-11-07 Teva announces additional data from QNASL Phase III program on seasonal allergic rhinitis 0 None
2012-11-07 Arisaph’s ARI-3037MO well tolerated in healthy male and female volunteers 0 None
2012-11-07 Synta announces interim results from docetaxel Phase 2b/3 trial on NSCLC 0 None
2012-11-07 People more likely to take heart medicines in combo pill 0 5
2012-11-07 Treatment with AMG 145 reduces LDL cholesterol 0 None
2012-11-07 Positive results from Santarus and Pharming’s RUCONEST Phase III trial on HAE 0 None
2012-11-07 Results from liraglutide and exenatide head-to-head comparison trial on type 2 diabetes 0 5
2012-11-07 Lexicon announces data from LX4211 Phase 2b trial on type 2 diabetes 0 None
2012-11-07 SCYNEXIS announces results from SCY-635 Phase 2a study on HCV 0 None
2012-11-07 AMG 145 can reduce LDL cholesterol levels by up to 66% after 12 weeks 1 None
2012-11-06 Positive results from POZEN's PA32540 Phase 3 trials presented at AHA Scientific Sessions 2012 0 None
2012-11-06 Cryopraxis/CellPraxis initiates recruitment in ReACT Phase III trial for refractory angina 0 None
2012-11-06 Sabin initiates Part II of Na-GST-1 vaccine Phase I hookworm trial 0 None
2012-11-06 Probiotic formulation can reduce cholesterol esters 0 None
2012-11-06 Celldex to present results from CDX-301 Phase 1 study in healthy volunteers 0 None
2012-11-06 Intravenous infusion of HDL cholesterol could reduce risk of subsequent heart attack 0 None
2012-11-05 No link between daily multivitamin use and reduction of major cardiovascular events in men 0 None
2012-11-05 Endo, Bioniche decide to end second Urocidin Phase III trial on non-muscle-invasive bladder cancer 0 None
2012-11-05 AcelRx commences dosing in ARX-04 sufentanil NanoTab Phase 2 study for acute and breakthrough pain 0 None
2012-11-05 PsiOxus receives UK government grant to initiate ColoAd1 Phase I/II trial for ovarian cancer 0 5
2012-11-04 Pradaxa use does not appear to increase serious bleeding 0 None
2012-11-03 Blog reports on meeting of world's largest HIV vaccine research network 0 None
2012-11-03 Isis Pharmaceuticals to receive $1.25M from Pfizer for continued advancement of EXC 001 0 None
2012-11-03 Data from four Phase 2 trials of AMG 145 to be presented at AHA Scientific Sessions 2012 0 None
2012-11-03 Bristol-Myers Squibb, Pfizer and Portola partner to conduct clinical study of PRT4445 and ELIQUIS 0 None
2012-11-03 Pfizer, Bristol-Myers Squibb announce data from ELIQUIS clinical trial on AF 0 None
2012-11-03 Lomitapide shows promise in treating homozygous familial hypercholesterolemia 0 None
2012-11-03 Tolvaptan shows promise in treating autosomal dominant polycystic kidney disease 0 3
2012-11-03 Top-line results from Aerie Pharmaceuticals' AR-13324 Phase 2a study on glaucoma 0 None
2012-11-03 Genkyotex announces positive results from GKT137831 Phase I studies on healthy subjects 0 None
2012-11-03 Intensified antibiotic treatment can improve prognosis of patients with TB meningitis 0 None
2012-11-03 Phase II study to evaluate Medivir/Janssen's simeprevir and Vertex against HCV 0 None
2012-11-02 Advanced breast cancer that has spread to the brain could be treated with drug combination 0 None
2012-11-02 Virginia G. Piper, TESARO announce initiation of TSR-011 clinical trial for advanced cancer 0 None
2012-11-02 Imatinib mesylate effectively treats children with neurofibromatosis type 1 tumors 0 5
2012-11-02 Link between ChemoFx Drug Response Marker results and RFS of cervical cancer patients 0 None
2012-11-02 Takeda, Affymax announce data from OMONTYS Phase 3 studies on anemia due to CKD 0 None
2012-11-02 Janssen, Vertex to evaluate TMC435 and VX-135 in Phase 2 HCV study 0 3
2012-11-02 TransTech Pharma to complete TTP054 Phase 2 trial on type 2 diabetes 0 None
2012-11-02 Malarial drug shows promise in stopping breast cancer 0 None
2012-11-02 Inotek announces final data from trabodenoson Phase 2 trial on PAOG or ocular hypertension 0 1.5
2012-11-01 Multiple sclerosis disease activity reduced by leukaemia drug, even when first-line treatment has failed 0 None
2012-11-01 Omeros initiates enrollment in OMS824 Phase 1 trial for schizophrenia and Huntington's 1 None
2012-11-01 Nitisinone treatment effectively prevents tyrosinemia in children 0 None
2012-11-01 Encouraging results from Gilead’s TAF Phase 2 trial on HIV-1 infection 0 None
2012-11-01 Single dose of etanercept can improve chronic neurological dysfunction from stroke or TBI 1 4.2
2012-11-01 Advaxis updates preliminary data from ADXS-HPV Phase 2 trial on cervical cancer 0 None
2012-11-01 FibroGen announces presentation of FG-4592 Phase 2 data on anemia at ASN Kidney Week 2012 1 None
2012-11-01 Isis announces preliminary data from ISIS-STAT3 Phase 1 study on cancer 0 None
2012-11-01 Additional data from EnVivo’s EVP-6124 Phase 2b trial on AD presented at CTAD meeting 0 None
2012-11-01 AKP America commences ART-123 Phase 3 trial in severe sepsis patients with coagulopathy 0 None
2012-10-31 Orexo initiates OX51 Phase II trial in patients undergoing prostate biopsy 0 None
2012-10-31 Nabilone shows promise in treating diabetic neuropathy 0 None
2012-10-30 Top-line results from Neuraltus’ NP001 Phase 2 study on amyotrophic lateral sclerosis 0 5
2012-10-30 Doxepin oral rinse relieves mouth pain from head and neck cancer treatment 0 None
2012-10-30 TTP488 slows cognitive decline in patients with mild to moderate Alzheimer's 0 None
2012-10-30 Positive results from Celldex’s CDX-1401 Phase 1 study on solid tumors 0 None
2012-10-29 Positive interim data from XBiotech monoclonal antibody Phase II study for type 2 diabetes 0 None
2012-10-29 Antidepressant doxepin eases pain associated with oral mucositis 0 None
2012-10-29 Par to acquire Handa's ANDA for generic Seroquel XR 0 None
2012-10-29 Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients 0 None
2012-10-29 AstraZeneca commences FASLODEX Phase III study for hormone receptor-positive metastatic breast cancer 0 None
2012-10-29 Nonclinical data on Provectus PV-10 oncology drug presented at 27th SITC 0 None
2012-10-29 GTx to continue enobosarm Phase III trials for muscle wasting in patients with NSCLC 0 None
2012-10-26 Intracoronary and IV abciximab during angioplasty do not result in differences in myocardial damage 0 None
2012-10-26 Journal of Pediatrics assesses issues surrounding lack of clinical drug trials for neonates 0 None
2012-10-26 Resveratrol does not appear to offer metabolic benefits in healthy women 0 None
2012-10-26 Durata completes target enrollment in dalbavancin Phase 3 trial for ABSSSI 0 None
2012-10-25 Prasugrel reduces cardiovascular events among patients managed medically for ACS 0 None
2012-10-25 Thrasos completes $35 Million financing for development of THR-184 against AKI 0 None
2012-10-25 BioLineRx intends to conduct interim analysis of BL-1020 Phase II/III trial for schizophrenia 0 None
2012-10-25 Ophthotech announces data from Fovista Phase 2b trial on wet AMD 0 5
2012-10-25 Azaya Therapeutics commences ATI-0918 bioequivalence study in ovarian cancer 0 None
2012-10-24 Bayer announces data from riociguat Phase III trial on CTEPH 0 None
2012-10-24 Probiotic supplementation improves health-related quality of life during common cold 0 None
2012-10-23 Genzyme, Alnylam partner to develop and commercialize RNAi therapeutics against ATTR 0 None
2012-10-23 Abbott announces results from HUMIRA clinical studies on ulcerative colitis 0 5
2012-10-23 Derma Sciences to initiate DSC127 Phase 3 program in diabetic foot ulcers 0 None
2012-10-23 Possible overlap exists between inflammatory bowel disease and IBS 0 None
2012-10-23 Sickle cell disease treatments: An interview with Dr Niihara, CEO of Emmaus Medical 0 4
2012-10-23 Interim results from CEL-SCI's Multikine Phase III study on head and neck cancer 0 None
2012-10-23 Sanofi presents overview of Phase II and III trials for quadrivalent influenza vaccine 0 None
2012-10-22 Initiation of dinaciclib Phase 2b/3 CLL trial triggers $2M milestone payment from Merck 0 None
2012-10-22 GORE Septal Occluder receives FDA approval for use in REDUCE clinical study 0 None
2012-10-22 PLoS ONE publishes review of AntiViral-HyperActivation Limiting Therapeutics clinical trial 0 None
2012-10-22 Rhythm presents RM-131 Phase 1 clinical trial results for diabetic gastroparesis at ACG 2012 0 None
2012-10-22 Patients with AF experience more GI bleeding with rivaroxaban use 0 None
2012-10-22 Bayer announces data from riociguat Phase III pulmonary arterial hypertension trial 0 None
2012-10-20 Drospirenone-containing birth control pills associated with increased risk of blood clots 0 None
2012-10-19 ACT TIL therapy effective in treating metastatic melanoma 0 None
2012-10-19 Linezolid proves effective in treating drug-resistant TB 0 None
2012-10-19 Neuralstem initiates second cohort NSI-189 Phase Ib trial in major depressive disorder 0 None
2012-10-19 Long-term multivitamin use associated with prevention of cancer in middle-aged and older men 0 None
2012-10-18 Ustekinumab shows positive results in decreasing debilitating effects of Crohn's Disease 0 None
2012-10-18 Phase 3 study of INLYTA fails to meet primary endpoint in treatment-naïve patients with RCC 0 None
2012-10-18 Trial results of first new TB vaccine candidate in 90 years expected next year 0 None
2012-10-17 Bayer’s riociguat Phase III trial data on pulmonary hypertension to be presented at ACCP meeting 0 None
2012-10-17 Chloride-restrictive intravenous strategy may decrease incidence of AKI among critically ill patients 0 None
2012-10-17 Resverlogix commences RVX-208 Phase 2 trial in pre-diabetes mellitus 0 None
2012-10-16 NIAID-funded study to evaluate PPSV23 and PCV13 in Phase Iib pneumococcal trial 0 None
2012-10-16 Saint Louis University to participate in PPV23 vaccine trial for pneumonia 0 None
2012-10-15 Civitas to present CVT-301 Phase 1 study results at Parkinson's Disease Therapeutics Conference 0 None
2012-10-15 Enrollment complete in Idera's IMO-3100 Phase 2 trial for psoriasis 0 None
2012-10-15 FIGHT HLH Consortium receives EUR 6 million FP7 grant for testing NovImmune's NI-0501 0 None
2012-10-15 Data from Genkyotex’s GKT137831 Phase I studies to be presented at Kidney Week 2012 0 None
2012-10-15 No link between folic acid, vitamin B6 and 12 and increased risk of colorectal adenoma 0 None
2012-10-15 GlaxoSmithKline to make clinical trial data available to other researchers 0 None
2012-10-15 Genzyme announces key data from AUBAGIO Phase III trial on multiple sclerosis 0 None
2012-10-15 Merck announces results from odanacatib Phase II trial on post-menopausal osteoporosis 0 5
2012-10-12 Study compares two drug combinations for use as deep sedation during oral surgery 0 None
2012-10-12 Biogen Idec announces new data from BG-12 Phase 3 studies on RRMS 0 4.5
2012-10-12 Results from Aldagen’s ALD-401 Phase II trial on ischemic stroke 0 5
2012-10-12 Top-line results from Pfizer’s ALO-02 Phase 3 study on chronic non-cancer pain 0 None
2012-10-11 Enrollment complete in Euthymics’ amitifadine phase 2b/3a trial for major depressive disorder 0 None
2012-10-11 UCI neuro-oncologist to lead DCVax Phase II trial in glioblastoma multiforme 0 None
2012-10-11 Women respond much better than men to treatment of CFL with rituximab 0 None
2012-10-11 Leading scientists select first drugs to be evaluated in Alzheimer's clinical study 0 None
2012-10-10 NewLink Genetics to launch algenpantucel-L Phase 3 study in pancreatic cancer 0 None
2012-10-10 Mayo researchers discover new therapy for patients with neuromyelitis optica 1 None
2012-10-10 CRI, MedImmune partner to advance cancer immunotherapy research 0 None
2012-10-10 GSK, Aeras to advance clinical development of TB vaccine 0 None
2012-10-09 Johns Hopkins joins API’s Actimab-A Phase I/II trial in acute myeloid leukemia 0 None
2012-10-09 Lilly announces detailed results from solanezumab Phase 3 trials on Alzheimer's 0 None
2012-10-09 New data from Genzyme's AUBAGIO and LEMTRADA clinical trials to be presented at ECTRIMS 0 None
2012-10-09 Clinical trial to investigate safety and effectiveness of Elagolix against endometriosis 0 None
2012-10-08 New neuroprotective agent for stroke patients potentially found 0 None
2012-10-08 NCI awards Cellerant SBIR contract to develop Megakaryocyte Progenitor Cell therapy for thrombocytopenia 0 None
2012-10-08 Trevena reports completion of TRV027 Phase 2a study in advanced heart failure patients 0 None
2012-10-08 Positive results from Cempra's IV solithromycin Phase 1 study 0 None
2012-10-08 Data from GTx's enobosarm Phase IIb study on cancer to be presented at SIOG meeting 0 None
2012-10-06 Oral medication as effective as Botox injections for treating incontinence in women 0 None
2012-10-06 Rember revamped for Phase 3 testing in behavioral-variant frontotemporal dementia 0 None
2012-10-05 Subcutaneous formulation of ORENCIA® (abatacept) for the treatment of moderate to severe active rheumatoid arthritis approved by European Commission 0 None
2012-10-05 MannKind completes enrollment in AFREZZA Phase 3 clinical studies for type 1 and 2 diabetes 0 None
2012-10-05 Botox injections effectively treat urinary urgency incontinence in women 0 None
2012-10-05 Favorable preliminary results from XenoPort’s XP23829 Phase 1 trial on RRMS, psoriasis 0 None
2012-10-05 Top-line data from Pfizer’s Prevenar 13 Phase 3 trial on pneumococcal disease 0 None
2012-10-04 Mexiletine improves patient-reported stiffness in nondystrophic myotonia 0 None
2012-10-04 Penn researchers to begin Microbion's BisEDT gel Phase 2 trials in post-surgical orthopedic infections 0 4.5
2012-10-04 Circassia commences ToleroMune phase 3 trial in cat allergen-induced rhinoconjunctivitis 0 None
2012-10-04 Estrogen/progesterone treatment started soon after menopause appears safe and effective 0 None
2012-10-04 Positive data from three Onconova Ex-RAD clinical trials on acute radiation syndrome 0 None
2012-10-04 Merck announces data from MK-3102 Phase IIb trial on type 2 diabetes 0 None
2012-10-04 Vitamin D3 intake does not reduce incidence or severity of upper respiratory tract infections 1 None
2012-10-03 Mexiletine use improves stiffness in patients with nondystrophic myotonias 0 None
2012-10-03 Boehringer Ingelheim, Lilly announce data from LY2605541 Phase II study on type 2 diabetes 0 None
2012-10-03 Positive results from Noven’s LDMP Phase 3 clinical studies on menopausal VMS 0 None
2012-10-03 Biomarkers can increase success rate of clinical trials for breast cancer drugs by almost 50% 0 None
2012-10-02 Omega-3 fatty acid supplements could slow key biological process linked to aging 0 5
2012-10-02 Novel therapy shows promise in treating multiple myeloma following stem cell transplants 1 None
2012-10-02 Loyola launches experimental immune system therapy clinical trial for melanoma in the Midwest 0 None
2012-10-02 OS data from ImmunoGen's trastuzumab emtansine Phase III trial on breast cancer 0 None
2012-10-01 Addition of ficlatuzumab to gefitinib may be effective in select subsets of patients with NSCLC 0 None
2012-10-01 Takeda, Seattle Genetics announce preliminary data from brentuximab vedotin phase I study on sALCL 0 5
2012-10-01 Active Biotech, Ipsen announce new data on biomarkers from tasquinimod Phase II study in CRPC 0 None
2012-10-01 Exelixis announces interim data from cabozantinib phase 2 trial on metastatic CRPC 0 None
2012-10-01 Combination of dabrafenib and trametinib delays development of treatment resistance in MM patients 0 2
2012-10-01 Crizotinib effectively treats patients with ALK-positive lung cancer 0 None
2012-10-01 Exelix reports preliminary data from cabozantinib phase 1 study on solid tumors 0 None
2012-10-01 New trial results on pazopanib and temsirolimus have important implications for patients with RCC 0 None
2012-10-01 Lilly announces new data from two Phase II ramucirumab trials on NSCLC 0 None
2012-09-29 Sorafenib does not improve overall survival among patients with NSCLC 0 None
2012-09-29 ARIAD announces initial results from AP26113 Phase 1/2 trial on non-small cell lung cancer 0 None
2012-09-29 Drug combinations show promise against metastatic melanoma 0 None
2012-09-29 Synta announces results from ganetespib Phase 2b trial on NSCLC 0 None
2012-09-29 Exelixis announces preliminary results from BRIM7 Phase Ib trial on BRAFV600 mutated MM 0 None
2012-09-29 New trial data shows improvements in treatment of esophageal and gastrointestinal cancers 0 None
2012-09-29 Intarcia announces results from ITCA 650 phase 2 study on type 2 diabetes 0 None
2012-09-29 MicroDose completes third and final MDT-637 Phase 1 study on RSV infection 0 None
2012-09-28 Provectus amends and expands protocol for PV-10 Phase 1 hepatocellular carcinoma study 0 None
2012-09-28 Conditionally reprogrammed cells help identify effective therapy for HPV-positive RRP 0 None
2012-09-28 Melatonin supplementation improves sleep in hypertensive patients on beta-blockers 0 None
2012-09-28 BioLineRx’s BL-1020 safe and effective in treating schizophrenia 0 None
2012-09-28 OncoGenex commences custirsen Phase 3 trial in non-small cell lung cancer 0 None
2012-09-27 Early, intensive therapy with adalimumab can help treat rheumatoid arthritis 0 None
2012-09-27 GW to evaluate effectiveness of glucose-lowering drugs against type 2 diabetes 0 None
2012-09-27 Amakem commences AMA0076 Phase 2a study in glaucoma and ocular hypertension 0 None
2012-09-27 Enrollment complete in Boehringer Ingelheim’s nintedanib phase III studies for IPF 0 None
2012-09-27 Positive results from Sobi, Biogen Idec's rFIXFc Phase 3 trial on hemophilia B 0 None
2012-09-27 Antibiotic therapy can effectively treat acute appendicitis 0 None
2012-09-27 Enrollment complete in Resverlogix‘s RVX-208 Phase 2b trial on cardiovascular disease 0 None
2012-09-26 NOXXON commences NOX-A12 Phase IIa trial in relapsed MM 0 None
2012-09-26 Dexamethasone use during tonsillectomy not associated with excessive bleeding in children 0 None
2012-09-26 Lonafarnib clinical trial for progeria has scientific roots in basic biology discoveries 0 None
2012-09-26 PsiOxus initiates ColoAd1 phase I/II trial in metastatic solid tumours 0 None
2012-09-26 UCSD evaluates safety and tolerability of dexanabinol in Phase I brain cancer study 0 5
2012-09-25 Positive results from Antares Pharma’s VIBEX MTX clinical study on rheumatoid arthritis 0 None
2012-09-25 OncoSec establishes UW as second enrolling site for OMS-I100 Phase II metastatic melanoma trial 0 None
2012-09-25 Chronic respiratory disease treatments: an interview with Dr Sven Jan-Anders Karlsson, CEO of Verona Pharma 0 4.7
2012-09-25 New clinical trial to evaluate DEX-M74 against hereditary inclusion body myopathy 2 None
2012-09-25 Lonafarnib proves effective for children with progeria 0 4.6
2012-09-24 Study to examine SYMPLICITY renal denervation system for treatment-resistant hypertension 0 4
2012-09-24 Ohr commences Phase II clinical trial of Squalamine for wet-AMD 0 None
2012-09-24 RXi completes dosing in RXI-109 Phase 1 study for dermal scarring 0 None
2012-09-24 Sanofi chooses OnPoint clinical trial management system from BioClinica 0 None
2012-09-24 Encouraging results from CTI’s pacritinib phase 1 study on relapsed/refractory lymphoma 0 None
2012-09-24 Boehringer Ingelheim completes enrollment in nintedanib Phase III trials for IPF 0 None
2012-09-24 Denosumab effective in treating giant-cell tumor of the bone 0 None
2012-09-24 Radioactive iodine should only be used in treatment of some patients with papillary thyroid cancer 0 None
2012-09-21 EMA CHMP adopts positive opinion for ELIQUIS to prevent stroke, systemic embolism in NVAF patients 0 None
2012-09-21 Study finds drug may aid some autism patients 0 None
2012-09-21 Radioactive iodine may predispose young thyroid cancer patients to second primary malignancies 0 None
2012-09-21 ChromaDex announces findings from pTeroPure Phase 2/3 trial on high blood pressure 0 None
2012-09-21 Data from Navidea’s Lymphoseek Phase 3 studies on solid tumors to be presented at ESSO 0 None
2012-09-21 Medivir’s simeprevir and TMC647055 to enter phase IIa combination trial for HCV genotype-1 0 None
2012-09-21 Positive results from Galleon GAL-021 second Phase I study on respiratory depression 0 None
2012-09-21 Cytochroma commences CTAP101 phase 3 study in secondary hyperparathyroidism 0 None
2012-09-20 Lund University professor to coordinate oral insulin study for type 1 diabetes 1 None
2012-09-20 Aerpio Therapeutics commences AKB-9778 Phase 1b/2a trial in diabetic macular edema 0 None
2012-09-20 APR-246 can restore function of defective p53 and activate apoptosis in cancer cells 0 None
2012-09-19 FDA Division of Neurology Products, CoLucid reach agreement for lasmiditan development strategy 0 None
2012-09-19 Positive data from Nektar’s NKTR-192 Phase 1a study on acute pain 0 None
2012-09-19 Navidea commences enrollment in [18F]NAV4694 Phase 2 study for Alzheimer's 0 None
2012-09-18 Abiraterone acetate confirmed to offer significant survival benefit to advanced prostate cancer patients 0 None
2012-09-18 Pfizer announces that 14 abstracts for tofacitinib to be presented at ACR/ARHP annual meeting 0 None
2012-09-18 Thalidomide effective in treating disabling cough among people with idiopathic pulmonary fibrosis 0 None
2012-09-18 Apixaban offers minor added benefit for adult patients after hip replacement 0 None
2012-09-18 Positive data from Aprea’s APR-246 Phase I/II study on blood or prostate cancer 0 None
2012-09-18 Important data from Pfizer’s lung cancer and RCC portfolios to be presented at ESMO Congress 0 None
2012-09-18 Compelling data from two ITS Flunisyn Phase I clinical trials against multiple strains of influenza A 0 None
2012-09-17 Anthera to initiate blisibimod Phase 3 program for systemic lupus erythematosus 0 1
2012-09-17 vasopharm's explorative phase IIa NOSTRA trial in TBI meets clinical endpoints for safety 0 None
2012-09-17 Positive results from Targacept TC-5619 Phase 2 trial for inattentive-predominant attention deficit/hyperactivity disorder 0 None
2012-09-17 Jennerex Phase 2 JX-594 clinical data for hepatocellular carcinoma presented at ILCA meeting 0 None
2012-09-15 Study estimates drug concentrations of Truvada and tenofovir to reduce risk of HIV among MSM 0 None
2012-09-15 UMDNJ, Proteonomix to conduct UMK-121 Phase 1 trial in end-stage liver disease 0 None
2012-09-14 Clinical trial results signal 'promise, unresolved challenges' in finding effective dengue vaccine 0 None
2012-09-14 Hyperuricemia associated with more severe hepatic ATP depletion in response to fructose intake 0 None
2012-09-14 Emmaus Medical to complete target enrollment in L-Glutamine Phase III trial for sickle cell disease 0 None
2012-09-14 Senesco initiates SNS01-T cohort 2 trial in multiple myeloma 0 None
2012-09-13 Biodel initiates BIOD-123 Phase 2 trial in Type 1 diabetes 1 None
2012-09-13 Positive results from Edison’s EPI-743 phase 2A study on Leigh Syndrome 0 5
2012-09-13 Glenmark's GBR 500 enters Phase II clinical development for severe ulcerative colitis 0 None
2012-09-13 Positive data from Tetraphase Pharmaceuticals’ eravacycline Phase 2 trial on cIAI 0 None
2012-09-12 Data from Oncolytics’ REOLYSIN Phase III combination trial on head and neck cancers 0 None
2012-09-12 Transcept completes enrollment in TO-2061 Phase 2 trial for obsessive compulsive disorder 0 None
2012-09-12 MD Anderson joins API’s Actimab-A Phase I/II trial in acute myeloid leukemia 0 None
2012-09-12 Gene therapy regimen can safely restore immune systems to children with Bubble Boy disease 0 None
2012-09-12 Leading dengue fever vaccine candidate 30% effective in first large clinical trial 0 None
2012-09-12 Daily low-dose inhaled corticosteroids do not benefit asthmatics 0 4
2012-09-12 Researchers present new results from RV144 HIV vaccine trial at AIDS Vaccine 2012 0 None
2012-09-12 e-Therapeutics initiates second ETS2101 phase I trial in solid tumours 0 None
2012-09-12 KaloBios commences KB003 Phase 2 trial in severe asthma 0 None
2012-09-12 Ginkgo biloba supplements fail to improve cognitive performance in multiple sclerosis 0 None
2012-09-12 Positive results from Santarus rifamycin SV MMX Phase III study on travelers' diarrhea 0 None
2012-09-11 GE Healthcare announces data from [18F]flutemetamol phase III studies on Alzheimer's 0 None
2012-09-11 Durata Therapeutics completes dalbavancin Phase 3 trials on ABSSSI 0 None
2012-09-11 Dengue vaccine breakthrough 0 None
2012-09-11 Pergamum initiates LL-37 Phase I/II trial in hard-to-heal venous leg ulcers 0 None
2012-09-11 Data from Sangamo BioSciences’ SB-728-T Phase 1 clinical programs on HIV/AIDS 0 4.8
2012-09-11 Palatin Technologies completes bremelanotide Phase 2B trial on female sexual dysfunction 0 None
2012-09-10 Top line results from Zalicus Synavive Phase 2b study in rheumatoid arthritis 0 None
2012-09-10 Atox Bio AB103 for Necrotizing Soft Tissue Infections granted FDA Fast Track designation 0 None
2012-09-10 Phase III data for Suvorexant, an investigational insomnia medicine, announced 0 None
2012-09-10 TauRx initiates LMTX Phase 3 trial in Pick's Disease 0 5
2012-09-10 New oral antiseptic spray effective in killing 99.9% of infectious airborne germs 0 None
2012-09-10 Antibiotic treatment more effective than placebo in patients with mild-to-moderate COPD 0 None
2012-09-07 Trevena to present TRV027 Phase 1 clinical data at 16th Annual Heart Failure Society of America Meeting 0 None
2012-09-07 Enrollment complete in DOUBle Phase 3 clinical trial of AzaSite Plus and DexaSite for blepharitis 0 None
2012-09-07 Adding bavituximab to docetaxel doubles overall survival in late-stage NS-NSCLC patients 0 5
2012-09-07 Crizotinib effective in shrinking tumors in patients with ALK positive non-small cell lung cancer 0 None
2012-09-07 The Institute of Cancer Research, CRT and Astex to discover and develop novel drug candidates 0 None
2012-09-07 Kalidex announces presentation of data on KPI-10 against MDR strains at ICAAC 0 None
2012-09-07 Durata completes target enrollment in dalbavancin Phase 3 trials for abSSSI 0 None
2012-09-06 Omeros files OMS824 IND with FDA to initiate clinical trials for cognitive disorders 0 None
2012-09-06 Clinical trial to test combination of two drugs in treating fibromyalgia 8 5
2012-09-06 Merck, Symphogen announce worldwide license agreement for Sym004 to treat cancers 0 None
2012-09-06 Baxter commences anti-MIF antibody Phase I trial in malignant solid tumors 0 None
2012-09-06 Targacept plans to pursue development of TC-5214 for overactive bladder 0 None
2012-09-06 ImmunoCellular completes enrollment in ICT-107 Phase II trial for glioblastoma 0 None
2012-09-06 Alnylam announces complete results from ALN-RSV01 Phase IIb trial on RSV infection 0 None
2012-09-06 Rigel commences R343 and R333 Phase 2 studies in allergic asthma, discoid lupus erythematosus 0 None
2012-09-05 Enrollment complete in ACADIA's pimavanserin Phase III trial for Parkinson's disease psychosis 0 None
2012-09-05 Epizyme commences EPZ-5676 Phase 1 study for MLL-r leukemia 0 None
2012-09-05 NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial 0 None
2012-09-05 Zalicus commences first of two Z160 Phase 2a clinical studies for chronic neuropathic pain 0 None
2012-09-05 Phase 1b trial validates efficacy of Pulmatrix PUR118 to treat COPD 0 None
2012-09-05 ImmusanT commences Nexvax2 clinical trials for celiac disease in New Zealand, Australia and the U.S. 0 None
2012-09-05 AlloCure commences AC607 Phase 2 clinical trial for acute kidney injury 0 None
2012-09-05 Avanir initiates enrollment in AVP-923 Phase II clinical trial for treatment of agitation in AD patients 0 None
2012-09-04 KYTHERA completes enrollment in ATX-101 Phase III trials for reduction of submental fat 0 None
2012-09-04 Biokine, BioLineRx sign license agreement to develop and commercialize BL-8040 for AML 0 None
2012-09-04 Data from ESTEVE’s S1RA E-52862 Phase I trial programme on pain 0 None
2012-09-04 Infliximab may offer new hope for people with difficult-to-treat depression 0 None
2012-09-04 High-dose vitamin D appears to help patients with TB recover more quickly 0 None
2012-09-03 New analyses from Esbriet RECAP study in IPF patients presented at ERS 2012 0 None
2012-09-03 Inhaled steroid drugs slow growth in children with asthma 0 None
2012-09-03 Combining tiotropium with olodaterol significantly improves lung function in COPD patients 0 None
2012-09-03 Boehringer Ingelheim announces data from olodaterol plus tiotropium Phase II COPD study 0 None
2012-09-03 Tiotropium improves lung function in symptomatic asthma patients on ICS/LABA 0 None
2012-09-03 Sosei highlights data from QVA149 clinical trials on COPD 0 None
2012-09-03 First data from Boehringer Ingelheim’s Respimat Phase III asthma program 0 None
2012-09-03 SPIRIVA to mark 10th anniversary with European Respiratory Society Congress 0 None
2012-09-03 Positive results from Elevation Pharmaceuticals’ EP-101 Phase 2b study on COPD 0 None
2012-09-01 Sophiris announces data from PRX302 transrectal safety study on Benign Prostatic Hyperplasia 0 5
2012-09-01 GenSpera plans to initiate G-202 Phase II trial in prostate cancer 0 None
2012-08-31 VLST, Pfizer enter in-licensing agreement for anti-CD40 monoclonal antibody 0 None
2012-08-31 Elan commences ELND005 Phase 2 study in Bipolar I Disorder 0 None
2012-08-31 Soligenix’s RiVax induces greater ricin neutralizing antibody levels in humans 0 None
2012-08-31 Enrollment complete in Arrowhead’s CALAA-01 phase 1b trial on solid tumors 0 None
2012-08-31 Sosei’s QVA149 Phase III study on COPD meets primary endpoint 0 None
2012-08-30 IQWiG examines added benefit of belimumab for patients with systemic lupus erythematosus 0 None
2012-08-30 Combination of POZEN’s PA32540 and clopidogrel results in greater antiplatelet effects 0 None
2012-08-30 Protalex announces results from PRTX-100 Phase 1b trial on active rheumatoid arthritis 0 None
2012-08-30 Collegium commences enrollment in Oxycodone DETERx Phase 3 study in chronic lower back pain 0 None
2012-08-30 Genmab, Janssen partner to develop and commercialize daratumumab for multiple myeloma 0 None
2012-08-30 Israel's Ministry of Health approves Medgenics’ INFRADURE Phase I/II clinical trials for hepatitis C 1 None
2012-08-30 Lilly decides to terminate pomaglumetad methionil Phase III trial on schizophrenia 0 None
2012-08-30 Elan commences ELND005 Phase 2 study in Bipolar I Disorder 0 None
2012-08-29 Sleep disorder treatment: an interview with Dr Seth Lederman, President and CEO of Tonix Pharmaceuticals 0 4.5
2012-08-29 Omitting aspirin leads to less bleedings but does not increase risk of stent thrombosis, MI 0 None
2012-08-29 Taking aspirin associated with reduced risk of death from prostate cancer 0 None
2012-08-29 Esperance completes EP 100 and paclitaxel Phase 2 combination trial on advanced ovarian cancer 0 None
2012-08-29 Top-line results from Rexahn’s Archexin Phase II study on metastatic pancreatic cancer 0 None
2012-08-29 Altheus Therapeutics initiates enrollment in Zoenasa Phase 2 study for ulcerative colitis 0 4.5
2012-08-28 Eplerenone shown to reduce cumulative heart failure hospitalisations 0 None
2012-08-28 Aeterna Zentaris commences enrollment in AEZS-130 Phase 2A trial for cancer cachexia 0 None
2012-08-28 Three Pulmatrix PUR118 clinical studies on COPD, asthma to be presented at ERS Annual Congress 0 None
2012-08-28 Positive results from Spinifex’s EMA401 Phase 2 trial on postherpetic neuralgia 0 None
2012-08-28 Global platelet reactivity effectively identifies ACS patients at high risk of ischemic events 0 None
2012-08-28 Copeptin estimates prognosis in patients with heart failure 0 None
2012-08-28 Alder’s initiation of ALD518/BMS-945429 Phase 2 trial triggers $3.5M milestone payment 0 None
2012-08-28 Personalized antiplatelet treatment leads to better outcomes in patients undergoing PCI 0 None
2012-08-28 Morphotek commences MORAb-004 Phase II metastatic soft tissue sarcoma trial 0 None
2012-08-28 America Stem Cell commences ASC-101 Phase I/II study in hematologic malignancies 0 None
2012-08-28 Neuralstem completes NSI-566 Phase I trial on amyotrophic lateral sclerosis 0 None
2012-08-27 Insulin glargine retards progression of atherosclerosis in high-risk people 0 None
2012-08-27 Update on Merck's development programs for vorapaxar, ER niacin/laropirprant and anacetrapib 0 5
2012-08-27 Additional data from Auxilium XIAFLEX phase III studies on Peyronie's disease 0 None
2012-08-27 Oral FluCide drug candidates effective in reducing lung viral load: NanoViricides 0 4
2012-08-27 Spironolactone should be considered as a treatment option in hypertensive patients with DHF 0 None
2012-08-27 Debiopharm initiates enrollment in triptorelin phase III study for central precocious puberty 0 None
2012-08-27 New data from Boehringer Ingelheim and Pfizer's tiotropium clinical studies on asthma, COPD 0 None
2012-08-27 LCZ696 demonstrates beneficial effects in heart failure patients with preserved ejection fraction 0 None
2012-08-27 Results from Roche's trastuzumab emtansine Phase III trial on HER2-positive breast cancer 0 None
2012-08-27 Prasugrel as safe as clopidogrel in preventing heart attack, stroke and death 0 None
2012-08-24 Seattle Genetics commences everolimus-SGN-75 combination phase Ib clinical trial for advanced RCC 0 None
2012-08-24 Lilly’s solanezumab Phase 3 trials on AD do not meet primary endpoints 0 None
2012-08-24 Dartmouth’s professor shares news of DAR-901 TB vaccine development 0 None
2012-08-24 Pre-emptive therapy better than valacyclovir prophylaxis in treating CMV in transplant recipients 0 None
2012-08-24 Diabetes journal reports results from novel experimental therapy 0 None
2012-08-24 Bristol-Myers Squibb terminates BMS-986094 Phase II development for treatment of hepatitis C 0 None
2012-08-24 Results from Biodesix VeriStrat phase II advanced lung cancer trials 0 None
2012-08-24 NW Bio receives MHRA approval to initiate DCVax-L Phase III GBM brain cancer trial in the U.K. 0 None
2012-08-24 AcelRx commences third ARX-01 Phase 3 study in post-operative pain 0 None
2012-08-23 Aeras, IDRI announce start of first ID93 + GLA-SE Phase I trial for tuberculosis 0 None
2012-08-22 Final data from Symphogen's rozrolimupab Phase 2 trial on primary immune thrombocytopenia 0 None
2012-08-22 CIRT to determine whether methotrexate can reduce heart attacks, strokes and CVD deaths 0 None
2012-08-22 PhaseBio commences Glymera Phase 2b study in type 2 diabetes 0 None
2012-08-21 Kineta receives regulatory clearance to commence ShK-186 Phase I trial in autoimmune disease 0 None
2012-08-21 DPT Labs, Imprimis sign agreement to commence work on Impracor clinical supplies 0 None
2012-08-21 MitoTarget Project and neurodegenerative diseases: an interview with Rebecca Pruss, Ph.D., CSO of Trophos 0 4
2012-08-21 Medivir initiates MIV-711 phase Ib trial in healthy volunteers 0 None
2012-08-21 Daily vitamin D intake protects against respiratory infections in children 0 None
2012-08-21 Encouraging results from Ocular Therapeutix's travoprost Phase II trial on glaucoma 0 None
2012-08-20 BioDiem and French partner VIVALIS a step forward in developing vaccines for diseases and related cancers 0 None
2012-08-20 ARIAD initiates multi-center ponatinib Phase 1/2 clinical trial for CML in Japan 0 None
2012-08-20 Enrollment complete in BDSI's pivotal pharmacokinetic study of BNX for opioid dependence 0 None
2012-08-20 Juventas commences treatment in JVS-100 Phase II STOP-HF trial for late stage heart failure 0 None
2012-08-18 FibeBiotics aims to prove benefits of polysaccharides in clinical trials 0 None
2012-08-17 Promising new treatment for bronchiectasis 0 2
2012-08-17 Montelukast improves respiratory disturbance and adenoid size in children with OSA 0 4
2012-08-17 Enzalutamide drug extends survival in people with advanced prostate cancer 0 None
2012-08-17 Preliminary results from Lexicon’s Phase 1 studies of LX2931 and LX7101 for RA 0 None
2012-08-16 Tofacitinib drug shows promise against moderate-to-severe ulcerative colitis 0 1
2012-08-16 Enzalutamide drug can extend life and improve QOL in men with advanced prostate cancer 0 None
2012-08-16 Medicago, IDRI receive FDA approval to commence Phase 1 H5N1 vaccine trial 0 None
2012-08-16 Cedars-Sinai's ICT-107 doubles median survival of patients with malignant brain tumor 0 None
2012-08-16 Genocea commences GEN-003 Phase 1/2a study in moderate-to-severe HSV-2 infection 0 None
2012-08-16 3SBio files APX001 IND application with SFDA in China 0 None
2012-08-15 Recognizing the role of international partnerships in global health 0 None
2012-08-15 Proteonomix receives FDA approval to commence UMK-121 Phase 1 trial in end-stage liver disease 0 None
2012-08-15 FDA requests Biovest to conduct second Phase III trial of BV301 for NHL 0 None
2012-08-15 Spectrum Pharmaceuticals initiates enrollment in Phase 2b ozarelix study for prostate cancer 0 None
2012-08-15 Compounds in cocoa may help decrease blood pressure 0 None
2012-08-14 Vandetanib given for advanced differentiated thyroid cancer almost doubles progression free survival 0 None
2012-08-14 Latrepiridine reduces level of at least two neurodegeneration-related proteins in mice 0 None
2012-08-13 CBIS initiates CS-TATI-1 GMP development plan 0 None
2012-08-13 Meritage commences OBS Phase 2 clinical trial for eosinophilic esophagitis 0 None
2012-08-13 Positive results from Acorda post-marketing commitment study of dalfampridine-ER for MS 0 None
2012-08-13 NIH awards ADi Phase II SBIR grant to scan Plasmodium falciparum proteome for protective antigens 0 5
2012-08-13 Orally effective FluCide anti-influenza drug candidate 0 None
2012-08-12 Study assesses gender differences in the efficacy of antiretroviral treatment 0 None
2012-08-12 Combination of novel drug therapy and PSA test can effectively detect prostate cancer 0 None
2012-08-12 Daily aspirin use may reduce overall cancer mortality 0 None
2012-08-12 Combination therapy does not change safety and efficacy relationship of TORISEL for advanced RCC 0 None
2012-08-12 PharmAthene receives clinical hold order from FDA for SparVax rPA anthrax vaccine program 0 None
2012-08-09 Herceptin® could potentially be delivered via a standard injection 0 None
2012-08-09 Clinical trials to test safety of 3K3A-APC in patients with ischemic stroke 0 None
2012-08-09 Combination of two existing pharmaceutical drugs shows promise against cocaine addiction 0 None
2012-08-09 Data from IMUC’s ICT-107 Phase I trial on glioblastoma multiforme accepted for publication 0 None
2012-08-09 Active Biotech, Teva to commence third Phase III study of laquinimod for RRMS 1 5
2012-08-09 Amgen announces decision to stop ganitumab Phase 3 trial in advanced pancreatic cancer 0 None
2012-08-09 Lightlake announces final data from naloxone nasal spray Phase II study on Binge Eating Disorder 0 None
2012-08-08 Omeros completes enrollment in first of two OMS103HP Phase 3 meniscectomy trials 0 None
2012-08-08 HCRI announces successful completion of randomization in DAPT Study 0 None
2012-08-08 Patients in clinical trials of new targeted cancer therapies appear to have lower risk of side-effects 0 None
2012-08-08 Corticosteroids show no clinical benefit in treating acute sinusitis 0 None
2012-08-08 UMass Medical, Serum Institute of India partner on anti-rabies monoclonal antibody pivotal trial 0 None
2012-08-07 Clinical trial targets breast cancer cells by injecting trastuzumab directly into the spinal fluid 0 None
2012-08-07 Novartis’ pasireotide offers symptom relief for patients with advanced neuroendocrine tumors 0 None
2012-08-07 Adalimumab effective in maintaining remission in pediatric patients with Crohn's disease 0 None
2012-08-07 Creatine may fight major depression in women 0 5
2012-08-07 Topline results from Janssen bapineuzumab Phase 3 trial on mild-to-moderate Alzheimer's 0 None
2012-08-06 Curemark receives FDA clearance for enrollment of children aged 9-12 in CM-AT study for autism 0 None
2012-08-06 Novel multireceptor-targeted somatostatin analogue found effective against neuroendocrine tumors 0 None
2012-08-06 Rexahn announces completion of RX-3117 exploratory Phase I clinical trial in cancer patients 0 None
2012-08-06 Nanobiotix, PharmaEngine partner to commercialize NBTXR3 for soft tissue sarcoma 0 None
2012-08-06 TWi Pharmaceuticals completes AC-201 phase II study on type II diabetes 0 None
2012-08-03 Caffeine may ease movement symptoms of Parkinson's 0 None
2012-08-03 Healthpoint Biotherapeutics announces results from HP802-247 Phase 2b trial on venous leg ulcers 0 None
2012-08-02 Combination of sitagliptin and lansoprazole offers clinical benefits for T1D patients 0 None
2012-08-02 Investigational drug shows promise against most severe form of congenital hyperinsulinism 0 None
2012-08-02 Combination hormonal therapy improves survival in advanced breast cancer 0 None
2012-08-02 Combination of anastrozole and fulvestrant extends survival in women with metastatic breast cancer 0 None
2012-08-02 Caffeine may help control movement in people with Parkinson's 0 None
2012-08-01 Breast cancer drug bevacizumab (Avastin): an interview with Dr Anna Dorothea Wagner 1 2.7
2012-08-01 Teplizumab type I diabetes prevention study now enrolls younger children 0 None
2012-07-31 InSite Vision commences enrollment in BromSite Phase 3 clinical trial 0 None
2012-07-31 Array BioPharma announces positive results from ARRY-797 Phase 2 trial on osteoarthritis 0 None
2012-07-31 GenSpera receives FDA clearance to commence G-202 Phase II trial in prostate cancer 0 None
2012-07-31 Latrepirdine appears effective in treating Alzheimer's disease in animals 0 5
2012-07-31 Top-line results from Pfizer's tofacitinib Phase 3 study on moderate-to-severe active RA 2 None
2012-07-30 New drug shows promise for Long QT syndrome 0 None
2012-07-30 FDA grants Senesco's SNS01-T orphan-drug designation to treat lymphomas 0 None
2012-07-30 Encouraging results from Tonix TNX-102 SL clinical trial for fibromyalgia syndrome 4 3
2012-07-30 Positive results from XIAFLEX phase IIIb multicord trial for Dupuytren's contracture 0 None
2012-07-30 Positive results from Vermillion OVA500 multi-center study for ovarian cancer 0 None
2012-07-30 Advaxis reports continued positive patient survival pattern in ADXS-HPV Phase 2 cervical cancer trial 0 None
2012-07-30 Early ART treatment delays AIDS-related health events in HIV-infected individuals 0 None
2012-07-30 Scientists discover new way to combat post-surgical scarring for glaucoma patients 0 None
2012-07-30 Paper highlights clinical and immunological activity of immatics’ IMA901 in renal cell carcinoma 0 5
2012-07-28 Genentech's BREVACTA study of ACTEMRA on rheumatoid arthritis meets primary endpoint 0 None
2012-07-28 Economist articles, blog examine research presented at AIDS 2012 conference 0 None
2012-07-28 Experimental dengue vaccine protects against 3 of 4 viral strains, study results show 0 None
2012-07-28 ARIAD Pharmaceuticals commences ponatinib Phase 3 trial in newly diagnosed CML 0 None
2012-07-28 Rituximab also benefits patients with kidney disorder 0 None
2012-07-27 TB combination drug: an interview with Mel Spigelman, MD, CEO and President of TB Alliance 0 None
2012-07-27 Anakinra can dramatically limit amount of brain damage in stroke patients 0 None
2012-07-27 HPTN study results show additional benefits of early ART in HIV clinical outcomes 0 None
2012-07-27 Navidea announces results from Lymphoseek Phase 3 trial on head and neck squamous cell carcinoma 0 None
2012-07-26 Preliminary findings from Protalex's PRTX-100 Phase 1b study on active rheumatoid arthritis 0 None
2012-07-26 New association found between basal cell carcinoma and eczema 0 None
2012-07-26 Raising dopamine levels in frontal cortex reduces impulsivity in healthy adults 0 None
2012-07-26 Bio-Path initiates enrollment in fourth cohort of Liposomal Grb-2 Phase I trial for blood cancers 0 None
2012-07-26 Multi-center clinical trial results demonstrate safety and efficacy of carfilzomib for multiple myeloma 0 4
2012-07-26 ImmunoCellular receives FDA IND clearance for ICT-121 Phase I trial in glioblastoma multiforme 0 None
2012-07-26 Bard completes enrollment in Lutonix DCB clinical trial for peripheral arterial disease 0 3
2012-07-26 Jennerex initiates JX-594 Phase 2 trial in advanced hepatocellular carcinoma 0 None
2012-07-26 CytRx commences aldoxorubicin plus doxorubicin Phase 1b trial in advanced solid tumors 0 None
2012-07-25 Karyopharm commences two KPT-330 phase 1 studies in cancers 0 None
2012-07-25 EntreMed commences ENMD-2076 Phase 2 study in triple-negative breast cancer 0 None
2012-07-25 New combination therapy for TB shows promise in Phase II study 0 None
2012-07-25 NBTI participates in ICT-107 phase II trial for glioblastoma multiforme 1 None
2012-07-25 Merck signs two licensing agreements for investigational HIV drug candidates 0 None
2012-07-25 Little evidence exists for potential HPV type competition in cross-sectional study 0 None
2012-07-25 Dapivirine Phase III trial now underway in Africa to treat HIV in women 0 None
2012-07-25 Favorable results from BioCryst’s ulodesine plus allopurinol Phase 2b trial on gout 0 None
2012-07-24 Novel combination drug regimen could be more effective than existing treatments for TB 0 None
2012-07-24 Topline results from first of four Phase 3 studies of Pfizer's bapineuzumab for Alzheimer's 0 None
2012-07-24 Pfizer’s Lyrica does not affect reproductive function in healthy males 0 None
2012-07-24 Debiopharm initiates Debio 8206 Phase III study on advanced prostate cancer 0 None
2012-07-24 TB combination drug trials progress 0 None
2012-07-24 Top-line result from Pfizer Bapineuzumab Phase 3 studies on Alzheimer's 0 None
2012-07-24 XenoPort initiates XP23829 Phase 1 study in healthy adults 0 None
2012-07-24 Ocular Therapeutix announces results from sustained release OTX-TP1 study on glaucoma 0 None
2012-07-24 Eating raisins may provide the same workout boost as sports chews 0 None
2012-07-23 Once-daily Gralise significantly reduces pain intensity in PHN patients 0 None
2012-07-23 New investment to fund Chiasma's Octreolin Phase 3 pivotal program for acromegaly 0 1
2012-07-23 Berg Pharma initiates BPM 31543 clinical trial for chemotherapy-induced alopecia 0 None
2012-07-23 Top-line results in Pfizer's Lyrica long term safety study for Generalized Anxiety Disorder 0 1
2012-07-23 Positive results from BrainStorm's interim NurOwn stem cell therapy clinical trial for ALS 7 None
2012-07-23 Cerulean commences dosing in CRLX101 Phase 2 study for ovarian cancer 0 None
2012-07-23 FDA meeting confirms Orexo regulatory submission of OX219 NDA on track 0 None
2012-07-23 Linagliptin safe and effective for long-term management of type 2 diabetes 0 None
2012-07-23 Foundation Fighting Blindness grants US$125,000 to Oxford BioMedica for UshStat Phase I/IIa trial 0 None
2012-07-23 Bayer, Onyx and Astellas announce results from Tarceva plus Nexavar Phase 3 trial on HCC 0 5
2012-07-23 Study addresses African patients’ attitudes toward HIV antiretroviral therapy 0 None
2012-07-22 BioDiem presents positive findings of their eye disease drug at international conference 0 None
2012-07-21 FDA grants accelerated approval for Kyprolis to treat multiple myeloma 0 None
2012-07-21 EMA CHMP issues positive opinion for conditional approval of brentuximab vedotin for lymphoma 0 None
2012-07-21 Regeneron, Sanofi initiate enrollment in SAR236553/REGN727 Phase 3 program 0 None
2012-07-20 Phosphate binders may cause unexpected harm to blood vessels in patients with CKD 1 3.3
2012-07-20 Silymarin does not offer significant improvements for patients with HCV 0 None
2012-07-20 T2Hemostasis provides reliable and rapid results when compared to conventional systems 0 None
2012-07-20 Bristol-Myers Squibb reports results from brivanib plus sorafenib phase III trial on HCC 0 4.3
2012-07-20 Conatus, University of Alberta initiate islet cell transplant Phase I/II trial of emricasan for diabetes 0 None
2012-07-20 Actinium completes Actimab-A Phase I/II study on Acute Myeloid Leukemia 0 None
2012-07-20 Viral Genetics initiates Phase 1 trial of MDT compounds for ovarian cancer 0 None
2012-07-19 NPR reports on Brazilian clinical trial of Truvada as prevention strategy 0 None
2012-07-19 Clinical trial to evaluate maraviroc-based PrEP regimens for HIV prevention 0 None
2012-07-19 Positive preliminary results from Feraheme phase III study on iron deficiency anemia 0 None
2012-07-19 Otsuka, Acucela commence rebamipide ophthalmic suspension Phase 3 trial in dry eye syndrome 0 None
2012-07-19 Angion Biomedica initiates BB3 Phase II trial in heart attack 0 None
2012-07-18 Silymarin does not provide greater benefit for patients with chronic HCV infection 0 None
2012-07-18 Combination prevention strategy trials to start later this year in Africa, GlobalPost reports 0 None
2012-07-18 Memantine boosts memory function in people with Down syndrome 1 5
2012-07-17 Anthera announces final set of clinical data from blisibimod Phase 2b study on SLE 0 None
2012-07-17 AstraZeneca plans to conduct ticagrelor plus clopidogrel clinical trial for PAD 0 5
2012-07-17 D-ribose effective in improving QOL in energy-depleted patients with FMS/CFS 0 5
2012-07-16 Positive results from Alnylam’s ALN-TTR02 Phase I trial on TTR-mediated amyloidosis 0 None
2012-07-16 Merck to present results from clinical studies on BACE inhibitors at AAIC 2012 0 None
2012-07-14 James J. Peters Veterans Hospital actively enrolls participants for NIC5-15 phase IIb trial in AD 0 5
2012-07-13 ACT treats fourth patient in U.S. clinical trial for Stargardt's Macular Dystrophy 1 5
2012-07-13 OncoMed commences dosing in OMP-54F28 Phase I clinical trial for advanced solid tumor cancers 0 None
2012-07-13 Cubist initiates CB-315 Phase 3 trial for Clostridium difficile-associated diarrhea 0 None
2012-07-12 Nottingham researchers to lead Avastin clinical study for AMD 0 None
2012-07-12 Maraviroc reduces incidence of GvHD in blood cancer patients after bone marrow transplantation 0 None
2012-07-12 New drug combination could offer hope to children with neuroblastoma 0 None
2012-07-12 Merck announces update on odanacatib Phase III trial for osteoporosis 0 None
2012-07-12 NOXXON commences Spiegelmer NOX-A12 Phase IIa trial in CLL 0 5
2012-07-12 Enrollment complete in Phase III IND study of Spinal Restoration's Biostat System 0 None
2012-07-12 Dolutegravir-based regimen demonstrates superiority over Atripla in treatment-naive adults with HIV-1 0 None
2012-07-11 Arrowhead initiates Adipotide Phase 1 trial in obesity 3 4
2012-07-11 BioInvent announces data from BI-204 phase IIa study on stable atherosclerotic vascular disease 0 None
2012-07-11 OncoSec establishes UCSF as second enrolling site for OMS-I110 Phase II Merkel cell carcinoma trial 0 None
2012-07-11 ImmunoGen announces start of IMGN853 Phase I trial for ovarian cancer, other solid tumors 0 None
2012-07-11 Chemotherapy improves survival for patients with periampullary cancer following resection 0 None
2012-07-11 HIV infection risk reduced by same drugs that treat HIV 0 None
2012-07-11 Nutrient cocktail can boost memory in patients with mild cognitive impairment 0 None
2012-07-10 Inovio commences SynCon vaccine phase I study in H1N1 influenza 0 None
2012-07-10 Inspiration receives FDA clinical hold order for IB1001 phase III studies on hemophilia B 0 None
2012-07-10 Iron supplementation decreases fatigue by almost 50% in nonanemic women 0 None
2012-07-09 Enrollment complete in Lux Biosciences Luveniq Phase 3 study for non-infectious uveitis 0 None
2012-07-09 Positive data from Tonix's sublingual TNX-102 PK study for fibromyalgia 0 None
2012-07-09 Acusphere completes MAA dossier for Imagify to detect CAD 0 None
2012-07-09 Positive interim results from Inspiration's OBI-1 Phase 2/3 study for acquired hemophilia A 0 None
2012-07-09 Ampio announces results from Optina trial on DME 0 None
2012-07-08 Bayer commences enrollment in BAY94-9027 Phase II/III trial for hemophilia A 0 None
2012-07-07 New Gateway-funded phase II ADAPT study for metastatic colorectal cancer 0 None
2012-07-06 Fingolimod offers minor added benefit for patients with RRMS 0 None
2012-07-06 Higher doses of Vitamin D may be most beneficial in reducing bone fractures in older adults 0 None
2012-07-05 Preventing post-operative delirium may improve recovery of cognitive ability in cardiac patients 0 None
2012-07-05 Eltrombopag can raise blood cell levels in some people with severe aplastic anemia 0 None
2012-07-05 Anti-cancer activity of HuCAL antibody revealed by new data from OncoMed 0 None
2012-07-04 Cancer Therapeutics reveals proof of concept for second development drug 0 None
2012-07-04 Live zoster vaccine associated with reduced risk of HZ in patients with immune-mediated diseases 0 None
2012-07-04 Shingles vaccine may not increase risk of varicella in people with auto-immune diseases 0 None
2012-07-04 TMC receives NIH grant to evaluate pepducin in heart disease patients 0 None
2012-07-03 Botulinum toxin may help prevent arm tremor in people with MS 0 None
2012-07-03 Savient's KRYSTEXXA improves HRQOL and physical function in patients with RCG 0 None
2012-07-02 ImmunoCellular to expand ICT-107 Phase IIb trial on GBM 0 None
2012-07-02 Onyx commences ENDEAVOR Kyprolis Phase 3 trial for relapsed multiple myeloma 0 None
2012-07-02 Cerulean commences dosing in CRLX101-Avastin combination study for metastatic renal cell carcinoma 0 None
2012-07-02 Enrollment complete in Cerulean CRLX101 Phase 2 study for non-small cell lung cancer 0 None
2012-07-02 Rexahn submits RX-5902 IND to FDA for treatment of advanced or metastatic solid tumors 0 None
2012-07-02 Sosei completes SO-1105 Phase I trial for oropharyngeal candidiasis in Japan 0 None
2012-07-02 Janssen seeks accelerated FDA approval for bedaquiline to treat MDR-TB 0 3
2012-07-02 Clinical results for Teva's biologic oncology candidates presented at MASCC/ISOO 2012 0 None
2012-06-29 A.P. Pharma announces additional data from APF530 Phase 3 study on CINV 0 None
2012-06-29 Lexicon announces results from two initial trials of LX4211 for type 2 diabetes 0 None
2012-06-29 Drug trial participants should be better informed about benefits and side-effects of placebos 0 None
2012-06-29 Once-daily pill for HIV is a safe and effective alternative to traditional antiretroviral regimens 0 None
2012-06-29 New drug for Type 2 diabetes results in less hypoglycaemia, less weight gain and perhaps less cardiovascular risk for patients 0 None
2012-06-29 Medivir, Bristol-Myers Squibb to initiate TMC435 and daclatasvir phase II combination study in HCV 0 None
2012-06-29 Results from Access’ MuGard Phase 4 trial on oral mucositis 0 None
2012-06-28 LUMC oncologist presents survival data for brentuximab vedotin at 17th EHA Congress 0 None
2012-06-28 Pediatric Hodgkin lymphoma can be treated without radiation and intensive chemotherapy 0 None
2012-06-28 Full results from Derma Sciences’ DSC127 Phase 2 trial on diabetic foot ulcers 0 None
2012-06-28 Anthera announces results from blisibimod Phase 2b study on SLE 0 1.5
2012-06-27 Combination of radiation therapies effectively treat prostate cancer, lower chances of recurrence 0 None
2012-06-27 SIR/TAC combination more effective in preventing GVHD after allogeneic blood cell transplantation 0 None
2012-06-27 Top-line final data from Provectus’ PV-10 phase 2 trial on metastatic melanoma 0 None
2012-06-27 Vitamin D and calcium supplements could increase risk of kidney stones 0 3
2012-06-27 Sunshine Biopharma completes Adva-27a cytotoxicity study on multidrug-resistant lung cancer 0 None
2012-06-27 First clinical trial to test cardiac drug regimen for DMD 0 None
2012-06-27 RXi Pharmaceuticals initiates RXI-109 Phase 1 trial to reduce surgical scars 0 None
2012-06-27 BioSpecifics commences XIAFLEX Phase II trial in human lipoma 0 None
2012-06-26 Positive results from Antares Pharma's VIBEX MTX human factors usability study for RA 0 5
2012-06-26 Degludec reduces risk of nighttime low blood sugar in elderly diabetic adults 0 None
2012-06-26 Investigational parathyroid hormone replacement effectively treats hypoparathyroidism 2 None
2012-06-26 Clinical trial to examine functional benefits of combined therapy against stroke 0 None
2012-06-26 New drug better than chemotherapy for skin cancer patients 0 None
2012-06-26 Experimental medication increases muscle strength in cancer patients with low testosterone levels 0 None
2012-06-26 Combination of liraglutide and insulin controls blood sugar in obese adults with T1D 0 None
2012-06-26 Sitagliptin appears to reduce severity of reactive hypoglycemia 0 None
2012-06-26 Male hormonal contraceptives applied daily to the skin reduce sperm production 0 None
2012-06-26 KaloBios’ KB001 shows promise against Pa pneumonia 0 None
2012-06-26 Experimental medication helps overweight patients with diabetes shed pounds 0 None
2012-06-26 CytRx achieves key milestone in advancing tamibarotene Phase 2b trial for NSCLC 0 None
2012-06-26 Sinovac provides update on EV71 vaccine Phase III trial on HFMD 0 None
2012-06-25 Standard aspirin dose may not protect diabetics against blood clots 0 None
2012-06-25 Degludec effectively lowers blood glucose with lower risk for hypoglycemia 0 None
2012-06-25 NIH awards Sirnaomics SBIR grant for developing STP705 siRNA wound healing product 0 None
2012-06-25 Neuralstem commences dosing in NSI-189 Phase Ib trial for major depressive disorder 0 None
2012-06-25 Positive results from Lexicon’s LX4211 Phase 2b trial on type 2 diabetes 0 None
2012-06-25 Study reinforces importance of educating parents and other caregivers of children with food allergy 0 None
2012-06-25 Major weight loss an added benefit of testosterone replacement therapy for men 0 3.1
2012-06-23 Deferasirox reduces elevated iron levels in patients with myelodysplastic syndrome 0 5
2012-06-23 Genentech's Perjeta helps people with HER2-positive metastatic breast cancer live longer 1 None
2012-06-23 AbGenomics raises $11 million in current financing round 0 None
2012-06-22 Alexza resubmits ADASUVE NDA to U.S. FDA 0 None
2012-06-22 Shanghai Institutes of Preventative Medicine, Gentris sign MOU to advance personalized medicine 0 None
2012-06-22 Aeterna Zentaris announces perifosine Phase 1 trial on neuroblastoma 0 None
2012-06-22 Iroko announces results from diclofenac Phase 3 study on post-surgical pain 0 None
2012-06-22 Data from MAP Pharmaceuticals’ LEVADEX clinical studies to be presented at AHS meeting 0 None
2012-06-21 Study to test NAC and aspirin for people diagnosed with bipolar disorder 1 None
2012-06-21 Levodopa/carbidopa intestinal gel reduces 'off' time in people with advanced PD 0 5
2012-06-21 Omega-3 fatty acid supplements can reduce inflammation in overweight older adults 0 None
2012-06-20 Furiex initiates MuDelta Phase III studies in IBS-D 1 None
2012-06-19 Positive results from Zalicus Z944 Phase 1 SAD clinical study for chronic inflammatory pain 0 None
2012-06-19 e-Therapeutics commences enrollment in ETS2101 phase I trial for brain cancer 0 None
2012-06-19 Gilead's elvitegravir MAA for HIV-1 infection receives EMA validation 0 None
2012-06-19 New patent filed for VAC-3S, an immunotherapy for treating HIV infections 0 None
2012-06-19 Antiarrhythmic short-term treatment useful for some patients 0 None
2012-06-19 Five abstracts evaluating Abbott's LCIG presented at Parkinson's disease congress 0 None
2012-06-18 Positive interim data from Innate MIS416 Phase 1/2 clinical trial for chronic progressive MS 0 None
2012-06-18 CINJ commences enrollment in three-drug combination trial for breast cancer 0 None
2012-06-18 Infinity voluntarily stops saridegib Phase 2 trial for chondrosarcoma 0 None
2012-06-18 Cancer publishes Aeterna Zentaris' perifosine Phase 2 trials in RCC 0 None
2012-06-18 Updated data from ARIAD’s ponatinib pivotal trial on CML or Ph+ ALL 0 None
2012-06-18 DBV Technologies’ Viaskin safe and effective in treating children with peanut allergy 0 None
2012-06-18 UW initiates enrollment in tosedostat phase II combination study for AML, MDS 0 None
2012-06-18 Positive results from ERYTECH Pharma asparaginase Phase II trials on ALL 0 None
2012-06-18 Updated results from two clinical trials of Bruton's ibrutinib for CLL/SLL 0 None
2012-06-18 Impressive results from blinatumomab Phase 2 study on B-precursor ALL 0 None
2012-06-16 Promising results from single iron dose study for fatigue treatment in iron deficient women 0 None
2012-06-16 Combination of low-dose vitamin D and calcium does not reduce fracture risk in women 0 None
2012-06-16 St. Michael's to investigate new treatments for prevention of brain injury complications 0 None
2012-06-16 Large-scale trial of vaginal ring that releases anti-HIV drug announced at health summit in London 0 None
2012-06-16 Otsuka, Bristol-Myers Squibb announce six-year data from SPRYCEL Phase 3 trial on CP-CML 0 None
2012-06-16 Study finds no evidence to support an effect of THC on MS progression 0 None
2012-06-16 Civitas commences CVT-301 Phase 2a trial in Parkinson's disease 0 None
2012-06-16 Less expensive ARV combination just as effective for women in developing countries as costlier ARVs, study shows 0 None
2012-06-15 Sanofi’s insulin glargine delays progression from pre-diabetes to T2DM 0 None
2012-06-15 Changing guidelines threaten important HIV drug trial 0 None
2012-06-15 Positive top-line results from Teva’s GALA Phase III trial on RRMS 0 None
2012-06-15 TGen, Scottsdale Healthcare open INNO-206 Phase 2 trial for pancreatic cancer 0 None
2012-06-15 Antioxidant rhSOD reduces risk of blindness in extremely low gestational age newborns 0 None
2012-06-15 Dyax to discontinue ecallantide Phase 2 trial for ACE inhibitor-induced angioedema 0 None
2012-06-15 Theraclone Sciences commences TCN-202 Phase 1 trial in CMV infection 0 None
2012-06-15 Quest receives FDA clearance to initiate oregovomab Phase II trial in ovarian cancer 0 None
2012-06-14 Hay fever vaccine shows efficacy in phase IIa trial 0 None
2012-06-14 AB Science announces results from masitinib phase 2 study on MS 0 None
2012-06-14 Updated survival data from Takeda’s brentuximab vedotin Phase II trial on HL 0 None
2012-06-14 Cancers often recur after treatment with single drugs that “target” tumor cells’ genetic pathways 0 None
2012-06-14 IBBR, Sanaria to receive Phase II SBIR grant from NIAID for malaria vaccine 0 None
2012-06-14 Sabin initiates novel human hookworm vaccine Phase 1 clinical trial 0 None
2012-06-14 NEJM hails vismodegib as ‘the greatest advance in therapy yet seen’ for advanced BCC 0 None
2012-06-14 Ophthotech’s Fovista anti-PDGF combination therapy superior to Lucentis for wet AMD 0 5
2012-06-14 Azaya announces final results from ATI-1123 Phase I study on cancers 0 None
2012-06-14 EnVivo to present results from EVP-6124 Phase 2b trial on AD at AAIC 2012 0 None
2012-06-13 Investigational Insomnia Medicine from Merck improved patients’ ability to fall and stay asleep according to new phase III Data 0 None
2012-06-13 ChromaDex’s pTeroPure safe for human consumption 0 None
2012-06-13 New combination therapy can help improve cure rates for neuroblastoma 0 5
2012-06-13 Long-term insulin use does not increase risk of heart disease in people with diabetes 0 None
2012-06-13 VaxInnate commences VAX161 Phase I trial in pandemic avian influenza 0 None
2012-06-13 Acorda commences AMPYRA clinical study for post-stoke deficits 0 3
2012-06-12 Almased helps patients with type 2 diabetes lose weight, gain better sugar control 0 None
2012-06-12 Initial trial results from KYTHERA’s second of two Phase III trials with ATX-101 0 None
2012-06-12 Individuals on statins more likely to experience fatigue with exertion 0 None
2012-06-11 Theramine may reduce chronic low back pain 0 4
2012-06-11 FDA accepts Avanir IND for AVP-923 to treat agitation in patients with AD 0 None
2012-06-11 Positive results from Cara’s CR845 Phase II study on acute post-operative pain 0 None
2012-06-11 BioSante to initiate two new LibiGel Phase III efficacy trials in FSD, HSDD 0 None
2012-06-11 Ampio’s CRO completes Optina clinical trial for DME 0 None
2012-06-11 Dapagliflozin more effective than sitagliptin for adult patients with type 2 diabetes 0 None
2012-06-11 Zafgen announces new data from two Phase 1 studies of beloranib on obesity 0 None
2012-06-11 Sanofi’s Lantus more effective than sitagliptin for people with type 2 diabetes 0 None
2012-06-11 Pre-operative aspirin therapy may reduce risk of acute kidney failure after CABG surgery 0 None
2012-06-11 Cebix announces data from Ersatta Phase 1 study on type 1 diabetes 0 None
2012-06-11 Amylin announces results from SYMLIN clinical studies on type 2 or 1 diabetes 0 5
2012-06-11 Amylin, Alkermes announce results from BYDUREON clinical study on type 2 diabetes 0 None
2012-06-11 Lilly, Boehringer Ingelheim announce results from linagliptin Phase III trial on T2D 0 None
2012-06-11 Incyte, Lilly announce 12-week results from baricitinib Phase IIb study on RA 0 None
2012-06-10 Lexicon presents six posters on LX4211 at ADA meeting 0 None
2012-06-08 CSL Behring rIX-FP granted Orphan Drug Designation to treat hemophilia B 0 None
2012-06-08 Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD 0 None
2012-06-08 Large-scale randomized treatment study on adrenocortical cancer 0 None
2012-06-08 Erivedge drug shows promise against advanced basal cell carcinoma 0 None
2012-06-08 Data from abatacept versus adalimumab Phase IIIb comparison study on RA 0 None
2012-06-08 Experimental drug tested against multi-drug resistant TB 0 None
2012-06-08 Banyan, Amarantus complete collaboration agreement related to TBI development program 0 None
2012-06-08 Sorrento receives $300,000 STTR grant to develop novel therapeutics against Staph infections 0 None
2012-06-08 NCI presents long-term outcomes from BiovaxID lymphoma vaccine Phase II trial at ASCO 2012 2 None
2012-06-08 MGH, HSG to conduct PBT2 clinical trial in Huntington's disease 0 4
2012-06-07 Enrollment complete in Advaxis’ ADXS-HPV Phase 2 study on CIN 2/3 0 None
2012-06-07 Clinical study shows positive effects of CAD106 vaccine against AD 0 None
2012-06-07 Biologic treatments reduce mortality risk in patients with rheumatoid arthritis 0 None
2012-06-07 Dengue fever vaccine 'may be in sight,' Reuters reports 0 None
2012-06-07 Clinical study demonstrates effectiveness of vismodegib in treating BCNS 0 None
2012-06-07 Savient announces results from KRYSTEXXA Phase III trials on gout-related kidney disease 0 None
2012-06-07 Debiopharm announces results from Debio 0932 Phase I study on cancer 0 5
2012-06-07 ADACTA trial: Tocilizumab more effective than adalimumab in treating RA 0 2
2012-06-06 AB Science announces data from development program of masitinib in GIST 0 None
2012-06-06 STELARA effectively reduces signs and symptoms of active psoriatic arthritis 0 None
2012-06-06 PhaseBio raises $48.4M in Series B financing 0 None
2012-06-06 Abbott announces results from HUMIRA Phase 3 study on axSpA 0 None
2012-06-06 Cardio-protective drug during cancer treatment may prevent heart damage in children 0 None
2012-06-06 Aeterna Zentaris announces results from perifosine Phase 1 trial on multiple myeloma 0 None
2012-06-06 Bayer announces updated data from radium-223 dichloride Phase III trial on CRPC 0 None
2012-06-06 Abbott commences elagolix Phase 3 trial in endometriosis 0 None
2012-06-06 New immune response data from Generex’s AE37 Phase II trial on breast cancer 0 None
2012-06-06 Positive updated interim data from Exelixis’ cabozantinib phase 2 trial on CRPC 0 None
2012-06-05 Lilly announces final results from ALIMTA Phase III study on NSCLC 0 4
2012-06-05 Three-drug regimen provides rapid, durable responses for multiple myeloma 0 None
2012-06-05 Soy protein may not enhance overall cognitive ability in women 0 None
2012-06-05 T-DM1 better than standard therapy in controlling breast cancer 0 None
2012-06-05 BioInvent, ThromboGenics announce results from TB-402 Phase IIb trial on VTE 0 None
2012-06-05 New PD-1 blocking antibody shows promise against advanced kidney cancer 0 3
2012-06-05 D-cycloserine may increase response to PTSD psychotherapy 0 None
2012-06-05 Updated results from three trials of Bruton's ibrutinib for treatment of CLL/SLL 0 5
2012-06-05 Parkinson’s vaccine: worldwide first clinical trial begins 0 None
2012-06-05 Cannabinoid therapy helps provide effective analgesia for cancer patients with pain 0 None
2012-06-05 Jennerex announces data from JX-594 clinical studies on cancer 0 None
2012-06-05 Esperance presents results from EP-100 Phase 1 study on solid tumors at ASCO annual meeting 0 None
2012-06-05 Results from Celgene’s ABRAXANE plus gemcitabine clinical study on resectable pancreatic cancer 0 None
2012-06-05 Ipsen, Active Biotech present OS data from tasquinimod Phase II study on CRPC at ASCO 2012 0 None
2012-06-05 Alnylam announces results from ALN-VSP Phase I study on liver cancers 0 2.2
2012-06-05 High doses of ginseng more effectively reduce cancer-related fatigue in patients 0 None
2012-06-05 Senesco reports on the progress of SNS01-T Phase 1b/2a study for multiple myeloma 0 None
2012-06-05 Exelixis reports data from cabozantinib phase 3 trial on MTC 0 None
2012-06-05 Promising data from Array BioPharma’s MEK162 Phase 2 trial on BRAF and NRAS mutant melanoma 0 None
2012-06-05 OncoGenex announces data from OGX-427 Phase 2 study on mCRPC 0 None
2012-06-05 Positive results from BioSpecifics’ XIAFLEX Phase III clinical program on Peyronie's disease 0 3
2012-06-05 Preliminary results from Incyte’s INCB024360 Phase I trial on solid tumors 0 None
2012-06-05 Antisense Pharma presents data from trabedersen Phase I/II cancer study at ASCO 2012 0 5
2012-06-05 Seattle Genetics, Agensys announce interim data from ASG-5ME phase I trial on CRPC 0 None
2012-06-05 Takeda announces updated results from orteronel phase 2 study on nmCRPC 0 None
2012-06-05 Ambit, Astellas commence quizartinib Phase 2b trial in relapsed/refractory AML 0 None
2012-06-04 Adamas to present update on Nurelin program at CHI Targeting Parkinson's Disease Symposium 0 None
2012-06-04 Aeterna Zentaris announces results from perifosine Phase 3 trial on colorectal cancer 0 None
2012-06-04 Polynoma initiates POL 103A Phase III trial in melanoma 0 None
2012-06-04 ViroPharma initiates maribavir Phase 2 program for CMV infections 0 None
2012-06-04 Advaxis to update preliminary data on ADXS-HPV Phase 2 trial for cervical cancer 0 None
2012-06-04 Exelixis reports positive interim data from cabozantinib phase 2 trial on HCC 0 None
2012-06-04 Onyx announces data from regorafenib Phase 3 trial on GIST 0 None
2012-06-04 Oncothyreon announces data from two clinical trials of PX-866 at ASCO meeting 0 None
2012-06-04 New data from ImmunoGen’s SAR3419 Phase I study on CD19+ NHL 0 None
2012-06-04 New data from OncoMed’s OMP-59R5 Phase I study on advanced solid tumors 0 None
2012-06-04 ImmunoGen reports data from T-DM1 Phase III trial on HER2-positive metastatic breast cancer 0 None
2012-06-04 Many men with metastatic prostate cancer live longer on continuous hormone therapy 0 None
2012-06-04 Positive results from Auxilium’s XIAFLEX phase III studies on Peyronie's disease 0 4.8
2012-06-04 Study shows valuable role of Mammostrat in assessing ER+ postmenopausal breast cancer patients 0 None
2012-06-04 Duloxetine drug reduces painful chemotherapy-induced peripheral neuropathy in majority of patients 0 None
2012-06-04 Results from Puma’s PB272 Phase I combination trial on metastatic HER-2 positive breast cancer 0 None
2012-06-04 Data from several clinical trials of ADCETRIS to be presented at ASCO annual meeting 0 None
2012-06-04 Results from Janssen's ZYTIGA plus prednisone Phase 3 study on mCRPC 0 5
2012-06-04 Genentech’s T-DM1 Phase III study on HER2-positive mBC meets primary endpoint 0 None
2012-06-04 Final results from ArQule and Daiichi Sankyo’s tivantinib phase 2 trial on HCC 0 None
2012-06-04 Roche to initiate three studies with T-DM1 for early stage HER2-positive breast cancer 0 None
2012-06-04 Favorable results from CytRx’s INNO-206 Phase 1b/2 trial on soft tissue sarcomas 0 None
2012-06-04 Interim results from Bristol-Myers Squibb’s BMS-936558 Phase 1 study on NSCLC, MM and RCC 0 None
2012-06-02 ZYTIGA Phase 3 study for metastatic prostate cancer presented at 48th ASCO 0 4.3
2012-06-02 Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer 0 None
2012-06-02 Lapatinib-pazopanib combination therapy not beneficial for patients with inflammatory breast cancer 0 None
2012-06-02 Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer 0 None
2012-06-02 Beneficial design element in sunitinib phase III clinical trial for gastrointestinal stromal tumors 0 None
2012-06-02 Two pharma companies plan international trials into targeted cancer treatments in the UK 0 None
2012-06-02 LDK378 compound well-tolerated in patients with ALK+ NSCLC 0 None
2012-06-02 New medication proves effective in slowing the spread of metastatic prostate cancer 0 None
2012-06-02 Liver metastases predicts shorter overall survival in men with mCRPC 0 None
2012-06-02 Lilly, Kowa announce results from PREVAIL U.S. study 0 None
2012-06-01 Results from A.P. Pharma’s APF530 Phase 3 trial on CINV 0 None
2012-06-01 Beta-carotene safe to use during radiation therapy for prostate cancer 0 None
2012-06-01 ImmunoCellular to present new data from ICT-107 Phase I trial on GBM 0 None
2012-06-01 NAC reduces irritability in children with autism 0 4
2012-06-01 Top-line results from Genzyme’s teriflunomide Phase III trial on MS 0 None
2012-06-01 NCI, Tau Therapeutics open enrollment in mibefradil Phase Ib glioma trial 0 None
2012-06-01 Oncothyreon commences PX-866 and vemurafenib Phase 1/2 combination trial for melanoma 0 None
2012-06-01 RXi’s RXI-109 IND receives FDA clearance to proceed into clinical trials 0 None
2012-06-01 Omeros commences planned PK substudy in Phase 3 clinical program of OMS302 0 None
2012-05-31 Ketamine reduces suicidal thoughts in patients with bipolar depression 0 None
2012-05-31 Taiho to initiate TAS-102 Phase III trial in colorectal cancer 0 None
2012-05-31 Top-line data from Flexion‘s FX005 Phase 2 trial on osteoarthritis 0 None
2012-05-31 Stiefel to acquire WBI-1001 licensing rights from Welichem 0 None
2012-05-31 CTI announces results from PIX301 phase 3 trial of Pixuvri for NHL 0 None
2012-05-31 Wellmune minimizes risk of URTI among marathoners 0 None
2012-05-31 Top-line results from Alnylam’s ALN-RSV01 Phase IIb trial on RSV infection 0 None
2012-05-31 Topline results from Alkermes’ ALKS 37 phase 2b study on opioid-induced constipation 0 None
2012-05-31 Exelixis commences cabozantinib phase 3 pivotal trial in mCRPC 0 None
2012-05-30 Corrected interim data from Vertex VX-809, KALYDECO combination Phase 2 study for CF 0 None
2012-05-30 DMARD not superior to oral therapy in long-term treatment of patients with JIA 0 None
2012-05-30 CytRx INNO-206 doxorubicin conjugate shows anti-multiple myeloma effects 0 None
2012-05-30 JTCC to present latest findings in blood-cancer research at ASCO annual meeting 0 None
2012-05-30 Positive results from RedHill’s RHB-103 bioequivalence trial on acute migraine 0 None
2012-05-30 Marshall Edwards initiates ME-344 Phase I trial in solid tumors 0 None
2012-05-30 NAC may be an effective therapy for some features of autism 0 None
2012-05-30 Positive results from Alkermes’ ALKS 5461 phase 1/2 study on MDD 2 None
2012-05-29 FDA accepts NDA filing for KYNAMRO to treat HoFH 0 None
2012-05-29 Oncos Therapeutics commences clinical study with oncolytic viruses 0 None
2012-05-29 Spectrum initiates enrollment in RenaZorb Phase 1 trial in healthy volunteers 0 None
2012-05-29 Enrollment complete in Advaxis’ ADXS-HPV Phase 2 trial for cervical cancer 0 None
2012-05-29 Abbott to highlight latest investigational research findings on HUMIRA at EULAR 2012 0 None
2012-05-28 Positive results from Acacia Phase II APD421 study in prevention of post-operative nausea & vomiting 0 None
2012-05-28 Medivir initiates MIV-711 phase I trial in bone disorders 0 None
2012-05-28 AngioPredict project to focus on patients with metastatic colorectal cancer 0 None
2012-05-28 Tβ4 offers both neurorestoration and neuroprotection after TBI 0 None
2012-05-28 Positive results from Sanofi and Regeneron’s SAR236553/REGN727 Phase 2 trial on heFH 0 4
2012-05-28 ESRD patients with diabetes may benefit from Baxter’s low-glucose PD regimen 0 None
2012-05-25 Linagliptin safe and effective for African American patients with type 2 diabetes 0 None
2012-05-24 Insmed initiates patient screening for ARIKACE phase 2 NTM lung disease trial 0 None
2012-05-24 ICS may prevent parapneumonic effusion in patients with CAP 0 None
2012-05-24 Preliminary results from Celldex’s CDX-011 Phase 2b breast cancer study 0 None
2012-05-24 Azithromycin can be effective treatment option for patients with BOS 0 None
2012-05-24 Molecular Therapy releases characteristics and activity of SNS01 formulation 0 None
2012-05-23 Phase I/II clinical trial of novel dialysate completed by Zytoprotec 0 None
2012-05-23 AVEO commences AV-203 Phase 1 study in advanced solid tumors 0 None
2012-05-23 Researchers to initiate Crenezumab clinical trial to treat Alzheimer's 0 None
2012-05-23 New clinical trial to evaluate HSP90 inhibitor plus hormonal therapy for breast cancer 0 None
2012-05-23 HVTN opens enrollment in GeoVax’s GM-CSF adjuvanted vaccine Phase 1 trial for HIV 0 None
2012-05-23 Daily use of vitamin C by smoking pregnant woman improves pulmonary function in babies 0 None
2012-05-23 Results from Boehringer Ingelheim’s Respimat Phase II study on moderate, persistent asthma 0 None
2012-05-23 Benefits of ICS treatment vary among children with differing demographic, clinical characteristics 0 None
2012-05-23 Data from Alvine’s ALV003 Phase 2A trial on celiac disease presented at DDW 2012 0 None
2012-05-22 Combination therapy does not reduce mortality rates associated with severe sepsis 0 None
2012-05-22 Gattex may represent new treatment approach for short bowel syndrome 0 None
2012-05-22 Diamyd Medical completes enrollment in NP2 Enkephalin Phase II study for cancer pain 0 None
2012-05-22 Bayer’s Nexavar Phase 3 trial on NSCLC does not meet primary endpoint 0 None
2012-05-22 New research reveals effective treatments for gastrointestinal conditions 0 None
2012-05-22 Enrollment complete in Xencor, MorphoSys’ MOR208 phase 1 trial for CLL 0 None
2012-05-22 Data from Janssen’s SIMPONI Phase 3 study on ulcerative colitis 0 5
2012-05-21 AltheRx reports positive Phase II results of Solabegron for OAB 0 None
2012-05-21 SERVE-HF study on effect of CSA treatment for stable heart failure enrolls 1,000th participant 0 None
2012-05-21 Ipsen, Active Biotech complete half of planned recruitment in tasquinimod phase III study for CRPC 0 None
2012-05-21 Hypertonic saline does not reduce rate of pulmonary exacerbations in young children with CF 0 None
2012-05-21 Statin therapy prevents cancer and reduces death risk in heart transplant recipients 0 None
2012-05-21 Oxytocin increases brain activations in children and adolescents with ASD 0 None
2012-05-21 Three-drug combo harmful for patients with idiopathic pulmonary fibrosis 0 None
2012-05-21 POZEN presents data from PA32540 Phase 1 gastric acid reduction study at DDW 2012 0 None
2012-05-19 Santarus to present UCERIS Phase III trial data on ulcerative colitis at DDW meeting 0 5
2012-05-19 Receptos to present scientific podium presentation about RPC1063 at DDW 2012 0 None
2012-05-19 Ceregene announces new data from CERE-120 clinical trial on Parkinson's 0 None
2012-05-19 Data from Purdue Pharma’s Butrans clinical trials to be presented at APS annual meeting 0 None
2012-05-19 Pfizer announces results from Lyrica clinical studies on fibromyalgia 1 5
2012-05-19 Data from Almirall, Forest Labs’ aclidinium studies on COPD to be presented at ATS conference 0 None
2012-05-19 Biovest announces new data from BiovaxID Phase II mantle cell lymphoma trial 0 None
2012-05-19 Daiichi Sankyo, ArQule complete enrollment in tivantinib plus erlotinib Phase 3 NSCLC trial 0 None
2012-05-19 Sigmoid provides financial and product development update 0 None
2012-05-18 ArQule to present positive tivantinib Phase 2 clinical data for hepatocellular carcinoma 0 None
2012-05-18 Urocortin 2 improves cardiac output in Phase II study for acute decompensated heart failure 0 None
2012-05-18 Breast cancer vaccine that elicits powerful immune response also improves recurrence rates 0 None
2012-05-18 Pharmacyclics announces clinical abstracts on ibrutinib to be presented at ASCO annual meeting 0 None
2012-05-18 Ipsen, Active Biotech to present data from tasquinimod phase II trial on CRPC at ASCO 2012 0 None
2012-05-18 Potential public-private partnership aims to bring TB vaccine trials to mines of Southern Africa 0 None
2012-05-18 Janssen’s NUCYNTA ER tablets more effective in providing pain management in adults with DPN 0 None
2012-05-18 Avraham initiates ladostigil Phase 2 trial in MCI 0 None
2012-05-18 Dabrafenib drug shrinks tumors in patients with melanoma brain metastases 0 None
2012-05-18 Patients with muscle-invasive bladder cancer benefit from accelerated MVAC 0 5
2012-05-18 Esperance initiates enrollment in EP-100 and paclitaxel Phase 2 combination trial for ovarian cancer 0 None
2012-05-18 Additional data from Tokai’s galeterone Phase 1 study on CRPC 0 None
2012-05-18 Pharmos completes levotofisopam phase 2a trial on hyperuricemia, gout 0 None
2012-05-18 Spectrum initiates ZEVALIN and MGd Phase 2 combination study in NHL 0 None
2012-05-17 Inovio SynCon avian influenza vaccine demonstrates broad coverage 0 None
2012-05-17 Lenalidomide following stem cell transplant can halt progression of blood cancer 0 None
2012-05-17 CHOP researcher leads trial of ALK inhibitor in neuroblastoma, lymphoma 0 None
2012-05-17 Abiraterone acetate can help eliminate prostate tumors 0 None
2012-05-17 First trial to investigate new drug combination for NSCLC 0 None
2012-05-17 PCSO-524 omega-3 complex may provide benefits for joint mobility and pain 0 1
2012-05-17 Treating prenatal maternal infections could improve birth outcomes, study suggests 0 None
2012-05-17 Updated results from Amgen’s blinatumomab Phase 2 study on ALL 0 None
2012-05-17 Ibrutinib shows promise against CLL in the elderly 0 None
2012-05-17 Data from Jennerex JX-594 clinical trials on cancer to be presented at ASCO annual meeting 0 None
2012-05-17 Reformulated anti-HIV gel may be safe for use in both vagina, rectum 0 None
2012-05-17 No significant differences in absorption between tablet and softgel capsule forms of folic acid 0 None
2012-05-17 Combination of daclizumab and vaccine improves survival of breast cancer patients 0 None
2012-05-17 May issue of NeuroPerspective assesses field of stroke therapeutics 0 None
2012-05-17 Results from Boehringer Ingelheim’s LUX-Lung 3 Phase III trial on stage IIIB or IV NSCLC 0 None
2012-05-16 Most depressed patients must make multiple attempts before finding an effective antidepressant 0 None
2012-05-16 First patient included in the phase II study of Amphinex® in head and neck cancer patients 0 None
2012-05-16 Achaogen’s plazomicin and levofloxacin safe and effective in treating cUTI, acute pyelonephritis 0 None
2012-05-16 Pfizer fails to meet primary endpoint in TORISEL Phase 3 study for advanced RCC 0 None
2012-05-16 Galectin Therapeutics commences Phase 1/2 trial of new treatment combination for advanced MM 0 4
2012-05-16 Positive data from Theraclone Sciences’ TCN-032 Phase 1 trial on influenza A infection 0 None
2012-05-16 Juventas begins enrollment in JVS-100 Phase IIa study for Rutherford Class 4 or 5 CLI 0 None
2012-05-16 Novelos completes I-131-CLR1404 Phase 1b trial on advanced solid tumors 0 None
2012-05-15 Svelte completes enrollment in DIRECT drug-eluting stent study 0 None
2012-05-15 Cubist announces results from CB-5945 Phase 2 studies on chronic non-cancer pain, OIC 0 None
2012-05-15 Pearl Therapeutics to present PT003 Phase 2b study on COPD at ATS meeting 0 None
2012-05-15 Smoked cannabis may be an effective treatment for spasticity 0 None
2012-05-15 BioAlliance Pharma commences Livatag phase III trial in hepatocellular carcinoma 0 None
2012-05-15 Lilly to present oncology data from more than 25 studies at ASCO annual meeting 0 None
2012-05-15 Fibrocell submits azficel-T Phase II study protocol with FDA to treat restrictive burn scars 0 None
2012-05-14 Phase II trial to examine effects of resveratrol on individuals with mild to moderate dementia 0 None
2012-05-14 Top-line data from S.L.A. Pharma’s Nalcol Phase 2 study on OIC 0 None
2012-05-14 Lenalidomide delays progression of multiple myeloma after stem cell transplant 0 None
2012-05-14 Chronic asthma sufferers may have new hope for relief due to two BWH research studies 0 None
2012-05-11 Positive results from Cytochroma CTAP101 Phase 2b clinical trial for CKD 0 None
2012-05-11 Arno AR-42 for neurofibromatosis type 2 receives EMA orphan-drug designation 0 None
2012-05-11 Top-line results from Takeda vedolizumab phase 3 trial on Crohn's disease 0 None
2012-05-11 Final results from Alnylam’s ALN-TTR01 Phase I trial on TTR-mediated amyloidosis 0 None
2012-05-11 Interim results from Seattle Genetics’ ADCETRIS phase II trial on CTCL 0 None
2012-05-11 NEJM publishes results from Celgene’s REVLIMID phase III studies on MM 0 None
2012-05-11 Rituximab does not appear to benefit children with INS 0 None
2012-05-11 Onconova advances rigosertib into new Phase II study for refractory MDS 0 None
2012-05-10 Macrocure's CureXcell Shows Strong Efficacy and Safety in Phase IV Hard-To-Heal Wounds Trial 0 5
2012-05-10 Fast track approval process for “breakthrough” drugs proposed in the U.S. 0 None
2012-05-10 Leishmaniasis vaccine trial begins in U.S., India 0 None
2012-05-10 Hygieia’s DIGS automatically adjusts insulin dosage in patients with diabetes 0 None
2012-05-10 Sunovion announces results from LATUDA open-label study for schizophrenia 0 None
2012-05-10 Lenalidomide improves overall survival for patients with multiple myeloma 0 None
2012-05-10 IDRI, Aeras partner to develop new TB vaccine candidate 0 None
2012-05-10 Resverlogix completes RVX-208 Phase 2b trial on CVD 0 None
2012-05-10 Janssen submits XARELTO sNDA with FDA to reduce risk of stent thrombosis in ACS patients 0 None
2012-05-09 New study to measure effectiveness of Vitamin B12 in preventing gestational diabetes 0 None
2012-05-09 Provectus announces final data from PV-10 Phase 2 trial on metastatic melanoma 0 None
2012-05-09 Sildenafil may improve cardiac function in children, young adults with single ventricle defects 0 4.5
2012-05-09 Antidepressives reduce risk of suicides in schizophrenic patients 0 None
2012-05-09 Two studies suggest long-term value of Deplin in treating MDD 0 4.6
2012-05-08 Rexahn submits Phase II protocol for Archexin clinical study for ovarian cancer 0 None
2012-05-08 Advaxis commences enrollment in ADXS-HPV Phase 1/2 study for head and neck cancer 0 None
2012-05-08 Certain males at higher risk of infection after receiving experimental HIV vaccine 0 None
2012-05-08 Oral zinc treatments may shorten duration of common cold symptoms in adults 0 None
2012-05-08 Everett Labs announces availability of Pregnitude for women with fertility problems 0 None
2012-05-08 Pall in-line filters can reduce severe complications, length of hospital stay in PICU 0 None
2012-05-08 New data from Acucela’s ACU-4429 Phase 2a trial on advanced dry AMD/geographic atrophy 1 None
2012-05-08 Otsuka announces results from aripiprazole Phase 3 trial on schizophrenia 0 None
2012-05-07 Positive results from PROLOR Biotech's hGH-CTP Phase II trial for growth hormone deficiency 0 None
2012-05-07 NovaDigm reports positive data from Phase 1 NDV-3 vaccine program 0 None
2012-05-07 Galleon GAL-021 safe and well-tolerated in Phase I respiratory depression clinical study 0 None
2012-05-07 Data from Idera IMO-8400 preclinical studies for SLE and psoriasis presented at AAI meeting 0 None
2012-05-07 Positive results from Dainippon Sumitomo Pharma's LATUDA trials for bipolar I depression 0 None
2012-05-07 KYTHERA ATX-101-10-16 trial for submental fat meets primary endpoints 0 None
2012-05-07 BioCryst first quarter revenues increase to $12.2 million 0 None
2012-05-05 Clinical data from Anacor’s tavaborole and AN2728 study to be presented at upcoming meetings 0 None
2012-05-05 Ocular Therapeutix initiates travoprost-loaded punctum plug trial in glaucoma 0 None
2012-05-05 Teva announces new data from women's health franchise 0 None
2012-05-05 Flavan-3-ols, SoyLife can improve biomarkers of CVD risk in postmenopausal type 2 diabetic patients 0 None
2012-05-05 Pfizer terminates Lyrica Phase 3 trial on neuropathic pain associated with HIV neuropathy 0 None
2012-05-05 Isis commences ISIS-APOCIIIRx Phase 2 study in hypertriglyceridemia 0 None
2012-05-05 Pfizer’s Lyrica Phase 3 study on pDPN fails to meet primary endpoint 0 None
2012-05-04 New analysis may help identify breast cancer patients who will benefit from immune suppressant 0 None
2012-05-04 CSL Behring commences C1-INH phase I/II study in hereditary angioedema 0 None
2012-05-04 Generon commences F-627 Phase II trial in breast cancer 0 5
2012-05-04 Abbott to purchase AP214 hormone analogue from Action Pharma 0 None
2012-05-04 Clinical trial to investigate statins in patients with acute severe respiratory failure 0 None
2012-05-04 Varenicline reduces alcohol intake among heavy-drinking smokers 0 None
2012-05-04 Lexicon to receive funding for LX4211 Phase 2 trial in type 1 diabetes 0 None
2012-05-04 GenVec receives NIAID’s Phase I SBIR grant to support RSV vaccine program 0 None
2012-05-04 NCIC CTG, Oncolytics to conduct REOLYSIN Phase II study in colorectal cancer 0 None
2012-05-03 HiLo trial sets new gold standard for thyroid cancer treatment 0 4
2012-05-03 SC formulation of Genentech’s ACTEMRA shows promise against RA 0 None
2012-05-03 Physician Therapeutics publishes results from Sentra PM clinical trial 0 None
2012-05-02 German BfArM grants Moberg Derma approval to initiate Limtop phase II actinic keratosis trial 0 None
2012-05-02 ImmuVen awarded $1.68M NIH Phase II SBIR grant to develop IMV0123 0 None
2012-05-02 Fish oil may improve outcomes for kidney patients undergoing hemodialysis 1 None
2012-05-02 JLGTD to publish results from Cutaneous Lysate study on vulvodynia 0 None
2012-05-02 Topline, interim results from Celldex Phase 2b EMERGE study of CDX-011 for advanced breast cancer 0 None
2012-05-02 Ultragenyx reports results from UX001 Phase 1 study on HIBM 0 None
2012-05-02 Inovio's SynCon vaccine for cervical dysplasias and cancers granted U.S. patent 0 None
2012-05-02 Sanofi Pasteur announces new quadrivalent influenza vaccine Phase III pediatric data 0 None
2012-05-02 Bevacizumab equivalent to ranibizumab in treating wet AMD 0 None
2012-05-02 CHR-3996 pill shows promise against advanced cancers 0 None
2012-05-02 Lixte submits IND with FDA to conduct LB-100 Phase I trial for cancer 0 None
2012-05-02 Gilead commences GS-1101 Phase 3 trial in CLL 0 None
2012-05-02 ACE inhibitors or ARBs could treat and prevent PTSD 0 1
2012-04-30 Rexahn obtains additional patent coverage for anti-cancer candidate RX-1792 in Japan 0 None
2012-04-30 JCO publishes Syndax erlotinib-entinostat Phase 2 study for advanced non-small cell lung cancer 0 None
2012-04-30 Enrollment complete in Zalicus Synavive Phase 2b clinical trial for rheumatoid arthritis 0 None
2012-04-30 Tolero granted exclusive global rights to commercialize MannKind's novel BTK compounds 0 None
2012-04-30 Pharmanest commences SHACT Phase I pharmacokinetic study 0 None
2012-04-30 Only few clinical trials are being conducted to test drugs in pediatric patients 0 None
2012-04-27 New URMC trial to evaluate carvedilol for high blood pressure 0 None
2012-04-27 Positive top-line results from Shire’s Vyvanse Phase 2 study on binge eating disorder 0 None
2012-04-26 CytRx commences INNO-206 Phase 2 clinical trial for pancreatic cancer 0 None
2012-04-26 First-ever study to evaluate effects of interaction between metamphetamines and Ibudilast 0 None
2012-04-26 ASIA honors SCI researchers with 2012 Apple Award 0 None
2012-04-26 Daily ART safe and effective in preventing mother-to-child HIV transmission 0 None
2012-04-25 Clinical and Translational Science Institute-Children's National awards pilot grant to GW researchers 0 None
2012-04-25 Positive results from Repligen's RG3039 Phase 1 study for spinal muscular atrophy 0 5
2012-04-25 Omega-3 supplements do not improve diastolic function in older adults 0 None
2012-04-25 S-equol effective in reducing menopausal hot flashes, muscle and joint pain among U.S. women 0 None
2012-04-25 Clinical trial to evaluate IGF-1 in children with SHANK3 deficiency 0 3.5
2012-04-25 Biogen Idec announces positive data from oral BG-12 second Phase 3 trial on RRMS 0 None
2012-04-24 Protein blend intake following resistance exercise may build muscles 0 5
2012-04-24 Gabapentin drug helps people to quit cannabis 0 2.3
2012-04-24 R-Tech Ueno completes RK-023 phase I study on hypotrichosis of the eyelashes 0 None
2012-04-23 Medgenics seeks FDA Orphan Drug Designation for INFRADURE to treat hepatitis D 0 None
2012-04-23 RVX-208 molecule increases apolipoprotein A-I production 0 None
2012-04-23 Oligomerix to advance tau protease inhibitor program with $2M Series A financing 0 2
2012-04-23 JT/Torii report positive results from ferric citrate Phase 3 study for hyperphosphatemia 0 None
2012-04-23 Asubio commences SUN13837 Phase 2 clinical trial for acute spinal cord injury 0 5
2012-04-23 Neutra announces clinical trials for Pure Plus Weight Loss supplement 0 None
2012-04-23 MicuRx completes MRX-I Phase 1 trial on MRSA and VRE infection 0 None
2012-04-21 VeriStrat test may be useful for NSCLC clinical decision-making 0 None
2012-04-21 LCIG improves quality of life, reduces symptoms of Parkinson's 0 5
2012-04-21 Results from Boehringer Ingelheim's afatinib Phase III lung cancer trial 0 None
2012-04-21 Positive results from Alnylam’s ALN-PCS Phase I trial on severe hypercholesterolemia 0 5
2012-04-20 New data from descriptive sub-analysis of patients with compensated liver cirrhosis 0 None
2012-04-20 New data provides hope for HCV non-responders 0 None
2012-04-20 New data shows consolidation of interferon-free revolution in HCV treatment 0 None
2012-04-20 Bristol-Myers Squibb announces results from daclatasvir plus asunaprevir Phase II HCV study 0 None
2012-04-20 Omega-3 fatty acids inhibit detrimental effects of smoking on arterial function 0 None
2012-04-20 Interferon beta-1a shows promise against MS 0 None
2012-04-20 Positive data from Synairgen’s SNG001 Phase II trial on asthma 1 None
2012-04-20 Final results from MSD’s VICTRELIS plus PEGINTRON Phase III trial on HCV treatment-related anemia 0 None
2012-04-20 Clinical study to evaluate high-dose vitamin D supplements for MS 0 None
2012-04-20 Palatin, AstraZeneca initiate second AZD2820 phase I trial in obesity 0 None
2012-04-19 Inform Genomics completes first phase in oral mucositis risk prediction study 0 None
2012-04-19 Final data from Santaris’ miravirsen Phase 2a trial on HCV to be presented at ILC 2012 0 None
2012-04-19 NSCLC patients with EGFR mutations benefit from erlotinib-first regimen 0 None
2012-04-19 New studies on personalized lung cancer treatment presented at 3rd ELCC 0 None
2012-04-19 Bristol-Myers Squibb, Janssen expand TMC435, BMS-986094 clinical collaboration agreement 0 4
2012-04-19 ARVO to host presentation of results from two clinical trials on neovascular AMD 0 None
2012-04-19 Perampanel drug may significantly reduce seizure frequency 0 5
2012-04-19 Researchers present findings of retrospective analysis of microbicide study at international conference 0 None
2012-04-19 Results from Presidio’s PPI-668 Phase 1a-1b trial on chronic HCV 0 None
2012-04-19 Positive results from CrystalGenomics’ CG100649 Phase 2b OA study 1 None
2012-04-19 Impax announces data from IPX066 Phase III study on Parkinson's 1 None
2012-04-18 Abbott reports positive results from LCIG Phase 3 trial for advanced Parkinson's disease 0 None
2012-04-18 Levodopa-carbidopa intestinal gel better than standard oral form to treat advanced Parkinson's disease 1 None
2012-04-18 Medgenics seeks IND approval to initiate EPODURE Biopump Phase IIb anemia study in ESRD patients 0 None
2012-04-18 Autologous HSPPC-96 vaccine clinically beneficial for GBM patients 0 None
2012-04-18 No added HIV risk with hormonal contraceptives 0 None
2012-04-18 Access reports positive interim results from MuGard Phase 4 clinical trial in oral mucositis 0 None
2012-04-18 New brain cancer vaccine with material from own tumors proves effective in clinical trial 0 None
2012-04-18 Idera commences IMO-3100 Phase 2 clinical trial for psoriasis 0 None
2012-04-17 ImmunoGen commences IMGN529 Phase I trial in NHL 0 None
2012-04-17 International Microbicides Conference to discuss state of HIV prevention research 0 None
2012-04-17 Metformin associated with reduced risk of Parkinson's in patients with diabetes 0 5
2012-04-17 ONO-4641 reduces number of lesions in people with MS 0 None
2012-04-17 Steroids still work better for patients with sciatica 0 None
2012-04-17 Morphotek commences MORAb-004 Phase II study in metastatic colorectal cancer 0 None
2012-04-16 Merck, Endocyte enter vintafolide development and commercialization agreement 0 None
2012-04-16 Decreasing GPA adherence among COX-2 users increases risk of upper GI complications 0 None
2012-04-16 New drug to detect beta-amyloid plaques may help diagnose AD earlier 0 None
2012-04-16 Florbetaben PET scan reliably identifies beta-Amyloid in the brain 0 None
2012-04-16 Positive top-line results from Biodel’s Phase 1 trial of two RHI-based formulations 0 None
2012-04-12 Newer antidepressant decreases depression in Parkinson's patients without worsening motor problems 0 None
2012-04-12 Enrollment complete for Ampio's multiple indication diagnostic clinical trials 0 None
2012-04-12 AcelRx commences dosing in second ARX-01 Phase 3 clinical trial for acute post-operative pain 0 None
2012-04-12 First clinical trial to clearly demonstrate effective prevention of post-ERCP pancreatitis 0 None
2012-04-12 FDA clears Cerecor’s FP01 IND for treatment of cough 0 None
2012-04-12 MacuCLEAR to initiate MC-1101 Phase III studies on early-stage AMD 0 None
2012-04-11 QRxPharma completes MoxDuo CR Phase 1 studies on chronic pain 0 None
2012-04-10 Omeros initiates enrollment in second Phase 3 trial of OMS302 0 None
2012-04-10 Provectus announces data from PV-10 Phase 2 study on metastatic melanoma 0 4
2012-04-10 Neutra to initiate new round of clinical trials on Pure Plus Weight Loss formula 0 None
2012-04-10 Proteonomix provides corporate and clinical trial updates 0 None
2012-04-09 New dietary supplement may arrest, lower rising PSA in men with recurrent prostate cancer 0 None
2012-04-09 Stealth announces results from three Bendavia Phase I clinical trials for mitochondrial dysfunction 0 None
2012-04-09 USPTO issues Notice of Allowance for Sunshine Biopharma's anti-tumor compound patent application 0 5
2012-04-09 NIH awards Winston SBIR grant to develop Civamide for postherpetic neuralgia of TN 1 None
2012-04-09 MD Anderson initiates Phase 1/2 entinostat-lapatinib ditosylate combination study in metastatic breast cancer 0 None
2012-04-09 Nuron Biotech licenses DNA amyloid beta 42 vaccine for AD 0 None
2012-04-09 Ampio submits pre-IND package on Zertane to FDA 0 None
2012-04-07 'Benefits and burdens' of participating in clinical research trials 0 None
2012-04-06 Regeneron, Sanofi announce clinical and regulatory update for ZALTRAP 0 None
2012-04-06 Key data from Boehringer Ingelheim's hepatitis C virus clinical trial programme 0 None
2012-04-06 Tonix completes TNX-102 pharmacokinetic study on fibromyalgia syndrome 0 None
2012-04-06 Sucampo announces positive results from lubiprostone phase 3 trial on OBD 0 None
2012-04-06 Spectrum’s apaziquone Phase 3 trials on bladder cancer do not meet primary endpoint 0 None
2012-04-06 Akebia completes AKB-6548 Phase 2 study for anemia in CKD patients 0 None
2012-04-05 Vaccine injections given directly into pancreatic cancer tumors associated with stable disease 0 5
2012-04-05 Belagenpumatucel-L improves survival for patients with stage 3B/4 NSCLC 0 None
2012-04-05 Results from Abbott’s multiple interferon-free Phase 2 HCV studies to be presented at ILC 2012 0 None
2012-04-05 BIND announces data from BIND-014 Phase 1 trials on prostate cancer 0 None
2012-04-05 Soy may effectively reduce menopausal hot flashes 0 None
2012-04-05 BIND presents results from BIND-014 Phase 1 trial on solid tumors at AACR 2012 0 None
2012-04-05 Soy isoflavones more effective in alleviating hot flashes 0 None
2012-04-05 Ventria completes VEN100 phase 2 trial on antibiotic-associated diarrhea 0 None
2012-04-04 Oral fluoroquinolones increase risk of retinal detachment 0 None
2012-04-04 Combination treatment shows promise against NSCLC patients ineligible for bevacizumab 0 None
2012-04-04 MedImmune's quadrivalent flu vaccine may protect children 0 None
2012-04-04 Combination of carboplatin, paclitaxel and RT3D shows promise against head and neck cancer 0 None
2012-04-04 Amgen, UCB commence CDP7851/AMG 785 Phase 3 trial in postmenopausal osteoporosis 0 5
2012-04-04 Combination of gemcitabine and TH-302 improves survival in advanced pancreatic cancer 0 None
2012-04-04 Topline results from GSK's seven of eight albiglutide Phase 3 studies on type 2 diabetes 0 None
2012-04-03 Lilly announces results of three preclinical studies that focus on c-MET receptor 0 None
2012-04-03 Funding shortfalls could hinder implementation of treatment as prevention strategies, Al Jazeera reports 0 None
2012-04-03 Onyx announces results from regorafenib Phase 3 trial on GIST 0 None
2012-04-03 New data demonstrates anti-cancer activities of Oncoprex 0 None
2012-04-03 Keryx does not meet primary endpoint in perifosine + capecitabine Phase 3 trial for colorectal cancer 0 None
2012-04-03 Positive outcome from AiCuris’ Letermovir phase 2b trial on HCMV infections 0 None
2012-04-03 Merck announces data from ZOSTAVAX Phase III study on shingles 0 None
2012-04-02 Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain 0 None
2012-04-02 Ampio, Australian TGA reach agreement over Zertane submission plan 0 2
2012-04-02 Enrollment complete in Oncolytics REOLYSIN combination trial for head and neck cancers 0 4.5
2012-04-02 NanoViricides reports positive pre-IND meeting with USFDA for FluCide 0 None
2012-04-02 Aeterna Zentaris X-PECT Phase 3 refractory advanced colorectal cancer trial fails to meet primary endpoint 0 None
2012-04-02 Clinical data for cabozantinib to be presented at ASCO annual meeting 0 None
2012-04-02 ViiV, Shionogi announce initial results from dolutegravir Phase III study on HIV-1 0 None
2012-04-02 RT3D may boost effects of two standard chemotherapy drugs in head and neck cancer patients 0 None
2012-04-02 Novartis achieves primary endpoints in all three of QVA149 Phase III studies on COPD 0 None
2012-04-02 Galeterone safe, effective for patients with CRPC 0 None
2012-04-02 Combination of cixutumumab and temsirolimus shrinks tumors in patients with Ewing's sarcoma 0 None
2012-04-02 Tokai Pharmaceuticals announces data from galeterone Phase 1 trial for CRPC 0 None
2012-04-02 Metformin may slow growth rate of prostate cancer in men 0 None
2012-04-02 Pazopanib demonstrates clinically meaningful activity in patients with refractory urothelial cancer 0 None
2012-03-31 Data from Cempra's CEM-101 Phase 2 trial on N. gonorrhoeae infections to be presented at ECCMID 0 None
2012-03-31 CSL Behring initiates rVIIa-FP Phase I study in hemophilia A and B 0 None
2012-03-31 Data from Cempra's CEM-101 Phase 2 trial on CABP to be presented at ECCMID 0 None
2012-03-31 ImmunoGen commences IMGN901 Phase II evaluation for SCLC 0 None
2012-03-31 Top-line results from Shire's SPD476 phase 3 trial on diverticulitis 0 None
2012-03-31 AlphaCore Pharma commences ACP-501 Phase 1 study in coronary arterial disease 0 None
2012-03-31 Cancer patients with CDI may benefit from DIFICLIR drug 0 None
2012-03-30 Needle-free vaccine shows promise against RSV in children 0 None
2012-03-30 Positive results from Genentech's T-DM1 Phase III trial on HER2-positive mBC 0 None
2012-03-29 Lilly's ixekizumab Phase II trial on plaque psoriasis meets primary endpoint 0 None
2012-03-29 Enrolment complete in Veloxis LCP-Tacro Phase III study in de novo kidney transplant patients 0 None
2012-03-29 Positive results from Nile's cenderitide Phase 1 trial on chronic heart failure 0 None
2012-03-29 Oncothyreon proposes underwritten public offering of common stock 0 None
2012-03-29 JDRF, iCo Therapeutics partner for iCo-007 Phase II trial in DME 0 None
2012-03-29 Navidea announces data from Lymphoseek Phase 3 study on oral and squamous cell cancers 0 5
2012-03-29 Regulatory agencies approve plans for e-Therapeutics' ETS2101 phase I trials in cancer 0 None
2012-03-29 DSMB recommends Bionovo to continue Menerba Phase 3 trial for hot flashes 0 None
2012-03-29 Althea provides Allena exclusive worldwide rights to broad hyperoxaluria portfolio 0 None
2012-03-29 Stem Cells reports results of Neuralstem ALS Phase I trial 0 5
2012-03-29 NEJM publishes results from Amgen's brodalumab Phase 2 trial on plaque psoriasis 0 None
2012-03-29 Clovis commences CO-1686 Phase I/II study in NSCLC 0 None
2012-03-29 Positive results from Allergan's BOTOX Phase III trials on idiopathic overactive bladder 0 None
2012-03-28 Out-of-hospital use of GIK as therapy for ACS patients needs to be assessed 0 None
2012-03-28 Imatinib improves RFS, overall survival in GIST patients after surgery 0 None
2012-03-28 Olaparib improves survival rates in platinum-sensitive relapsed serous ovarian cancer 0 None
2012-03-28 HAART does not completely suppress HIV in sexually active MSM 0 1
2012-03-28 First clinical trial to evaluate intravenous antibiotics for CF lung infection 0 None
2012-03-28 GIK can reduce cardiac arrest or death in patients with acute coronary syndrome 0 None
2012-03-28 Lower dose of thrombolytics can treat moderate pulmonary embolism 0 None
2012-03-28 Top-line results from two Targacept TC-6987 Phase 2 studies on asthma, type 2 diabetes 0 None
2012-03-27 NY-ESO-1 vaccine shows promise against ovarian cancer, melanoma 0 None
2012-03-27 Rivaroxaban safer, effective than standard therapy in treating PE 0 None
2012-03-27 SAR236553/REGN727 antibody reduces LDL by up to 72% in patients 0 None
2012-03-27 Researchers launch major aspirin trial to eradicate H. pylori 0 None
2012-03-27 Bolus intracoronary abciximab reduces infarct size in high-risk patients with STEMI 0 None
2012-03-26 CSL Behring commences enrollment in SCIg PATH trial for CIDP 0 None
2012-03-26 Theracurmin shows positive impact on human diastolic functions 0 4.7
2012-03-26 Promising results from Esperion ETC-1002 Phase 2 clinical trial for dyslipidemia 0 None
2012-03-26 Results from Merck's vorapaxar study on cardiovascular events 0 None
2012-03-26 ETC-1002 drug reduces LDL cholesterol levels in hypercholesterolemic patients 0 None
2012-03-26 Enrollment complete in Clovis' CO-101 pivotal study for metastatic pancreatic cancer 0 5
2012-03-26 Mutational profiling could determine which AML patients will benefit from dose-intensive chemotherapy 0 None
2012-03-26 Positive results from Amgen's AMG 145 Phase 1b study on patients with LDL-C 0 None
2012-03-26 New IVIG trial can reduce OCD symptoms in children with PANDAS 2 None
2012-03-26 GenVec announces data from respiratory syncytial virus vaccine program 0 None
2012-03-25 New cholesterol lowering drugs on the horizon 1 None
2012-03-23 Combination of everolimus and exemestane reduces spread of cancer in the bone 0 None
2012-03-23 China SFDA approves Taibang's clinical trials for human fibrinogen 0 None
2012-03-23 Emergent receives NIAID grant to advance development of MVA85A TB vaccine 0 None
2012-03-22 Working together to fight TB 0 None
2012-03-22 CINJ clinical trials leader receives 2012 Award of Excellence from HOPA 0 None
2012-03-22 Antidepressants can play a key role in relieving pain associated with OA 0 None
2012-03-22 Researchers unveil 'blueprint' to guide next steps in TB vaccine development 0 None
2012-03-22 International study into safety of NSAIDs reaches enrollment milestone 0 None
2012-03-22 BHR Pharma enrolls first 400 patients for BHR-100 pivotal trial for TBI 0 None
2012-03-21 TACT believes that Halo's HT-100 may effectively treat DMD 0 5
2012-03-21 TB Alliance launches Phase II clinical trial to test new drug regimen among people with TB, MDR-TB 0 None
2012-03-21 DIAN-TTU to receive $4.2M Alzheimer's Association research grant 1 None
2012-03-21 Alzheimer's Association awards $4.2M grant to DIAN-Therapeutic Trials Unit 0 None
2012-03-21 Enrollment complete in HAL Allergy PURETHAL Mites Phase II trial for allergic rhinitis/rhinoconjunctivitis 0 None
2012-03-21 Noven completes LDMP Phase 3 studies on menopausal VMS 0 None
2012-03-21 New drug makes chemotherapy more effective in treating acute myeloid leukemia 0 None
2012-03-21 Cardium commences Generx Phase 3 registration study in myocardial ischemia 0 None
2012-03-21 Positive data from Aerpio's AKB-9778 Phase 1 trial on DME 0 None
2012-03-20 PROLOR commences hGH-CTP Phase II trial in children with GHD 0 None
2012-03-20 Jennerex initiates JX-594 plus irinotecan Phase 1/2 trial in metastatic colorectal cancer 0 None
2012-03-20 Positive data from XENTION's XEN-D0103 phase 1 trial on AF 0 None
2012-03-20 AstraZeneca, Targacept announce top-line results from remaining TC-5214 Phase 3 studies on MDD 0 None
2012-03-20 New information on efficacy of CLA in treating Crohn's disease 0 None
2012-03-19 TB Alliance launches new combination drug trial 0 None
2012-03-19 Groundbreaking cystic fibrosis clinical trial to proceed after renewed funding 0 5
2012-03-19 NIH awards Avaxia $1.5M Phase II SBIR grant to develop antibody therapeutic for IBD 0 None
2012-03-19 Ampio completes partial planned interim review in Optina trial for diabetic macular edema 0 None
2012-03-19 Alnylam commences dosing in ALN-TTR02 Phase I clinical trial for TTR-mediated amyloidosis 0 None
2012-03-19 PaxVax announces FDA acceptance of IND for PXVX-0200 cholera vaccine 0 5
2012-03-19 Top-line data from Provectus' PH-10 Phase 2 trial on plaque psoriasis 0 None
2012-03-19 Convergence initiates CNV1014802 Phase II study in trigeminal neuralgia 0 None
2012-03-17 Oral BRAF inhibitor can extend survival to 16 months for patients with MM 0 None
2012-03-17 Adalimumab may decrease vascular inflammation in patients with psoriasis 0 None
2012-03-17 Positive data from VBL Therapeutics' VB-201 Phase 2 study on psoriasis, atherosclerosis 0 None
2012-03-17 Tarsa advances OSTORA NDA filing through $28M Series B financing 0 None
2012-03-17 SK Biopharmaceuticals initiates YKP10811 phase 2 trial in chronic constipation 0 None
2012-03-16 NEJM publishes results from Teva's laquinimod Phase III study on RRMS 0 None
2012-03-16 ARV given to HIV-positive children boosts preventive power of key malaria drug, study shows 0 None
2012-03-16 Kyolic AGE may reduce duration of cold and flu symptoms by 61% 0 None
2012-03-16 Abbott initiates enrollment in two HUMIRA Phase 3 trials for moderate to severe HS 0 None
2012-03-16 CSL Behring initiates FCH Phase III trial to control bleeding during cardiovascular surgery 0 None
2012-03-15 Fear of flying can be cured independently of YOH or after 4 sessions of VRET 0 None
2012-03-15 Combined therapy effective in treating patients with severe facial acne 0 4
2012-03-15 New topical gel decreases amount of time needed to treat actinic keratosis 0 None
2012-03-15 New RAGE inhibitor shows promise against Alzheimer's 0 None
2012-03-14 Consistent gains in five-year survival for children with acute lymphoblastic leukemia 0 None
2012-03-13 Bend Research announces licensing agreement with Affinium 0 None
2012-03-13 Inovio achieves strong T cell immune responses in PENNVAX-B Phase I HIV study 0 None
2012-03-13 Positive results from Bausch + Lomb, NicOx BOL‑303259‑X phase 2b study on OAG 0 None
2012-03-13 Medivir initiates two new HPC3001 and HPC3011 phase III trials in HCV 0 None
2012-03-13 Diacetylmorphine more cost-effective than MMT in treating street heroin users 0 None
2012-03-13 Reviva to initiate enrollment in RP503 phase 2 study for schizophrenia 0 None
2012-03-12 DNDi commences Oxaborole SCYX-7158 Phase I clinical trial for sleeping sickness 0 5
2012-03-12 Watson commences Esmya Phase 3 trial in women with anemia linked to uterine leiomyomas 0 None
2012-03-12 InflammaGen Therapeutics initiates Shok-Pak Phase 2 pilot study 0 None
2012-03-12 FDA clears Aradigm IND for Pulmaquin Phase 3 clinical trial in non-cystic fibrosis BE 0 None
2012-03-12 Botulinum toxin effective in treating OAB among women 0 None
2012-03-12 InflammaGen to initiate Phase 2 study of new drug/delivery platform for shock 0 None
2012-03-12 Top-line results from Inviragen's INV21 Phase 1 trial on HFMD 0 None
2012-03-12 Estrogen-only form of menopausal hormone therapy may protect against breast cancer 0 5
2012-03-12 New insight into causes of childhood pneumonia 0 None
2012-03-12 Tranylcypromine shows promise against AML 0 None
2012-03-11 BfArM grants Moberg Derma approval to initiate Limtop clinical phase I trial for actinic keratosis 0 None
2012-03-09 Ultragenyx completes UX001 Phase 1 study on hereditary inclusion body myopathy 0 None
2012-03-09 Enrollment complete in Palatin's bremelanotide Phase 2B trial for FSD 0 None
2012-03-09 MEDVAMC initiates Aeterna Zentaris' AEZS-130 Phase 2A trial in cancer cachexia 0 None
2012-03-08 Dr. Falk Pharma, Lipid Therapeutics enter license agreement for LT-02 to treat UC 0 5
2012-03-08 Positive phase II trial results from Circassia's ragweed allergy therapy 0 None
2012-03-08 MRF clinical trial to examine antigen-specific MS therapy 0 None
2012-03-08 Preliminary results of Partners PrEP Study show promise, investigators report at CROI 0 None
2012-03-08 Metformin drug appears to prevent growth of atherosclerosis in patients with HIV 0 5
2012-03-08 Doctors identify promising new treatment for hypophosphatasia 0 None
2012-03-08 Sosei initiates SO-1105 Phase I trial in oropharyngeal candidiasis 0 None
2012-03-07 New clinical trial: Pycnogenol improves signs and symptoms of menopause 0 None
2012-03-07 Ivabradine could save thousands of heart failure patients 0 None
2012-03-07 Timely treatment with Berinert provides faster symptom relief for HAE patients 0 None
2012-03-07 Shire to commence two Vyvanse and Concerta Phase 4 comparison trials for ADHD 0 None
2012-03-06 Bevacizumab drug improves cardiac output in patients with HHT 0 None
2012-03-06 AcelRx initiates ARX-01 Phase 3 study for treatment of post-operative pain 0 None
2012-03-06 MTPC, Medicago partner to develop and commercialize three new vaccines 0 None
2012-03-06 EntreMed plans to establish drug development office in China 0 1
2012-03-06 Merck announces results from AIT Phase III clinical study for ragweed allergy 0 None
2012-03-05 Millennium commences MLN8237 phase 3 trial in relapsed or refractory PTCL 0 None
2012-03-05 Merck announces success of pill against ragweed allergy 0 None
2012-03-05 Zalicus completes reformulated Z160 Phase 1 clinical trial for pain 0 None
2012-03-05 Thrombotech receives FDA IND approval for THR-18 Phase IIa clinical trial in stroke victims 0 None
2012-03-05 Anthera continues Phase 2b PEARL-SC clinical study in SLE patients 0 None
2012-03-05 Concert commences dosing in CTP-499 Phase 2 clinical trial for diabetic nephropathy 0 None
2012-03-05 FDA confirms FluCide pre-IND meeting date with NanoViricides 0 None
2012-03-05 BioLineRx granted Israeli approval for BL-7040 Phase II clinical trial for IBD 0 5
2012-03-05 Concert, Fast Forward partner to advance new approach to treat spasticity and pain in MS 0 None
2012-03-05 Exelixis initiates cabozantinib and abiraterone phase 1 combination trial in CRPC 0 2
2012-03-05 KYTHERA commences two ATX-101 Phase III trials for reduction of submental fat 0 None
2012-03-05 Meda announces positive results from three MP29-02 studies on allergic rhinitis 0 None
2012-03-03 SK Biopharmaceuticals' YKP3089 receives Korea Drug Development Fund 0 None
2012-03-03 Rigosertib drug shows promise against advanced pancreatic cancer 1 1
2012-03-03 Epicatechin-enriched cocoa shows promise against heart failure, Type 2 diabetes 0 1
2012-03-03 Long-term data from Baxter's HyQ clinical study on PI 0 None
2012-03-02 Preliminary results from Genentech's ACTEMRA monotherapy study on RA 0 None
2012-03-02 BioInvent completes enrollment in BI-204 phase IIa study for atherosclerosis 0 None
2012-03-02 UCSD first to treat glioma with investigational viral vector 0 None
2012-03-02 Methylnaltrexone may restore bowel function in critically ill patients 0 None
2012-03-01 Positive results from AltheRx Solabegron Phase II study on overactive bladder 0 None
2012-03-01 Parasitic worms could offer new treatment hope for MS patients 0 None
2012-03-01 Ruxolitinib boosts QOL and survival for patients with myelofibrosis 0 None
2012-03-01 NEJM publishes results from two Jakafi Phase III studies on MF 0 None
2012-02-29 Creabilis initiates CT327 Phase IIb trial in psoriasis vulgaris 0 None
2012-02-29 Study identifies how chemo drug combination kills pancreatic cancer cells 0 None
2012-02-28 DTMI, Bristol-Myers Squibb partner to broaden interactions 0 None
2012-02-28 FDA accepts Tau Therapeutics' mibefradil IND for treatment of cancer 0 None
2012-02-28 TAK-875 - an emerging therapy for Type 2 diabetes 0 5
2012-02-28 DBV receives FDA Fast Track Designation for Viaskin Peanut clinical development program 0 None
2012-02-28 Gedeon Richter and Forest Labs' cariprazine Phase III trials on schizophrenia meet primary endpoint 0 None
2012-02-27 TAK-875 as effective as glimepiride in treating type 2 diabetes 0 None
2012-02-27 Enrollment complete in Ikaria iNO Pivotal Phase III trial for BPD 0 None
2012-02-27 New drug improves glycaemic control with minimum risk of hypoglycemia in type 2 diabetics 0 None
2012-02-27 FDA issues complete response letter for Watson's progesterone vaginal gel 8% NDA 0 None
2012-02-27 The Lancet publishes Takeda's TAK-875 Phase 2 data on type 2 diabetes 0 None
2012-02-24 Researchers begin clinical trial of first visceral leishmaniasis vaccine 0 None
2012-02-24 Ipsen, Active Biotech report data from tasquinimod Phase II study on CRPC 0 None
2012-02-23 New CETP blockers continue to show promise as viable heart drugs 0 None
2012-02-23 Varenicline improves walking ability in patients with SCA3 0 None
2012-02-23 Vemurafenib nearly doubles survival for patients with metastatic melanoma 0 None
2012-02-23 Enrollment complete in Onyx Phase 3 ASPIRE trial for relapsed multiple myeloma 0 None
2012-02-23 IDRI launches LEISH-F3 + GLA-SE Phase 1 trial for kala-azar 0 None
2012-02-22 Combination of gemcitabine and MRK003 kills pancreatic cancer cells 4 5
2012-02-22 Immunization against flu during pregnancy can influence fetal growth 0 None
2012-02-21 FDA to review rejected weight loss drug Qnexa 0 None
2012-02-21 GTx fourth quarter net loss increases to $10.7 million 0 None
2012-02-21 S1 submits Lorexys IND application for HSDD and Female Sexual Dysfunction treatment 0 1
2012-02-19 Penn oncologist to discuss role of autophagy in fighting cancer at AAAS annual meeting 0 None
2012-02-18 Botox efficacy uncertain in treating migraine says NICE 3 None
2012-02-18 FDA prioritizes review of Ra-223 and MDV3100 for treating CRPC 0 5
2012-02-17 BYETTA-basal insulin combination therapy receives EMA CHMP positive opinion 0 None
2012-02-17 Midazolam autoinjector pen more effective in treating status epilepticus 1 None
2012-02-17 Intramuscular midazolam effective in treating status epilepticus 0 None
2012-02-16 Rapid intramuscular injection of midazolam drug is safe, effective for status epilepticus 0 None
2012-02-16 Thrombocytosis linked to severity of ovarian cancer 0 5
2012-02-16 Midazolam autoinjector may effectively treat status epilepticus 0 None
2012-02-16 UC Cancer Institute to enroll up to 60 patients for AMG 595 phase-1 trial 0 None
2012-02-16 RUMC conducts early phase trial of MSDC-0160 for dementia 0 None
2012-02-16 Combination of therapeutic cancer vaccines and chemotherapy shows promise 0 None
2012-02-15 UCSD opens lidocaine and amiodarone clinical trial to prevent SCA 1 None
2012-02-15 Amoxicillin not effective for patients with acute rhinosinusitis 0 None
2012-02-15 Paricalcitol does not improve clinical outcomes for patients with CKD 0 None
2012-02-15 Aganirsen demonstrates significant activity in two models of wet AMD, ischemic retinopathy 0 None
2012-02-14 Nilvadipine phase III trial for Alzheimer's launches in Europe 1 4.7
2012-02-14 Two studies demonstrate preliminary success of CyBorD in AL amyloidosis 0 None
2012-02-14 CyBorD regimen shows promise against AL amyloidosis 0 None
2012-02-13 Diffusion opens enrollment for TSC clinical trial for newly diagnosed primary brain cancer 0 None
2012-02-13 Third patient dosed in Phase 1/2 SMD trial using RPE cells derived from hESCs 0 None
2012-02-13 Progesterone vaginal gel 8% NDA transferred to Watson 0 None
2012-02-13 Trevena commences TRV130 Phase I clinical trial for severe post-operative pain 0 None
2012-02-13 Tiltan initiates TL-118 Phase 2 clinical trial for pancreatic cancer 0 None
2012-02-13 NTRR completes research and development of new erectile dysfunction treatment 0 None
2012-02-13 Santarus initiates enrollment in UCERIS Phase IIIb study for ulcerative colitis 0 5
2012-02-10 Preliminary results from Soligenix SGX201 Phase 1/2 trial on acute radiation enteritis 0 None
2012-02-10 Bupivacaine may effectively manage pain after total knee replacement 0 None
2012-02-09 Important to include men in HIV prevention, treatment programs 0 None
2012-02-09 Researchers examine effectiveness of Omega 3 in treating psychiatric symptoms 0 None
2012-02-08 Genzyme announces four-year data from eliglustat tartrate phase 2 trial on Gaucher disease type 1 0 None
2012-02-08 Exemestane has negative effect on postmenopausal women's bone health 0 None
2012-02-08 Center for LAM Research and Clinical Care at BWH to conduct phase I combination drug trial 0 None
2012-02-08 Patients with degenerative spondylolisthesis do not benefit from epidural steroid injections 0 5
2012-02-08 Routine 4CMenB immunizations effective against meningococcal strains in infants 0 None
2012-02-08 Cefpodoxime not effective in treating uncomplicated cystitis in women 0 None
2012-02-07 Anticoagulation drugs can prevent PE, DVT after total joint replacement 0 None
2012-02-07 Top-line results from Merck's vorapaxar clinical study on thrombosis 0 None
2012-02-07 Clinical Cancer Research publishes results of Aduro's ANZ-100 and CRS-207 Phase 1 studies 0 None
2012-02-07 Three new targeted drugs can lead to fatal cancer complications 0 None
2012-02-07 Merck completes two suvorexant Phase III trials on insomnia 0 None
2012-02-07 COC pill alleviates symptoms of painful menstrual periods 0 None
2012-02-07 FDA clears Neurelis IND to commence NRL-1 clinical trials for acute breakthrough seizures 0 None
2012-02-06 Preliminary results from Remedy Pharmaceuticals' RP-1127 Phase 2 trial on stroke 0 None
2012-02-06 Positive data from Chimerix CMX001 Phase 2 study on CMV disease 0 None
2012-02-06 Positive results from Chimerix CMX001 study for CMV in hematopoietic stem cell transplant recipients 0 None
2012-02-06 Orexigen reaches SPA agreement for Contrave outcomes trial with FDA 0 None
2012-02-06 GSK voluntarily pauses enrollment in GSK2251052 clinical trials for cUTI 0 None
2012-02-06 BioLineRx, Genoscience and RFS Pharma enter agreement for BL-8030 Hepatitis C treatment 0 None
2012-02-06 Neutra to initiate clinical trials of new all-natural weight-loss supplement 0 None
2012-02-04 African scientists' search for female-controlled microbicide gel to prevent HIV continues 0 None
2012-02-04 Aspirin plus clopidogrel unlikely to prevent recurrent strokes and may increase risk of death, bleeding 0 None
2012-02-04 Aspirin and warfarin similar in preventing deaths and strokes in heart failure patients 0 None
2012-02-04 G-CSF's AX200 does not improve stroke-related disability 0 None
2012-02-04 Soy isoflavone supplements do not reduce breast cancer cell proliferation 0 None
2012-02-04 Positive updated results from Aeterna Zentaris' AEZS-108 Phase 1 trial on CRPC 0 None
2012-02-03 Study to evaluate vitaminD3, omega3 and home exercise in preventing age-related chronic diseases 0 None
2012-02-03 Exelixis reports preliminary data from cabozantinib phase 1b trial on RCC 0 4
2012-02-03 New drug might effectively prevent clot-related strokes in patients with AF 0 None
2012-02-03 CSL Behring announces results of rIX-FP Phase I study on hemophilia B 0 None
2012-02-03 Enrollment opens in sorafenib vs. radioembolization in advanced hepatocellular carcinoma trial 0 None
2012-02-03 Researchers identify fexinidazole as potential new therapy for visceral leishmaniasis 0 None
2012-02-03 Rituximab shows promise against primary biliary cirrhosis 0 None
2012-02-03 New England Journal of Medicine publishes Diamyd Medical's antigen-based diabetes therapy study 0 None
2012-02-02 Takeda, SPI announce that lubiprostone phase 3 trial on OBD meets primary endpoint 0 None
2012-02-02 Ligand announces results from melphalan Phase II study on multiple myeloma 0 None
2012-02-01 FDA extends Novartis' Gleevec label to three-year treatment in patients with KIT+ GIST after surgery 0 None
2012-02-01 Clazosentan reduces risk of blood vessel spasm in patients with brain aneurysm 0 None
2012-02-01 Affinium initiates AFN-1252 Phase 2 trial in acute bacterial skin & skin structure infections 0 None
2012-02-01 Majority of children can safely quit anti-rejection drugs after liver transplant from parents 0 None
2012-02-01 Preliminary results from CINJ's Celebrex and Lipitor Phase II combination trial on prostrate cancer 0 None
2012-02-01 NIAID, Aeras partner for Phase II clinical trial of TB vaccine 0 None
2012-02-01 New combination clinical trial may improve outcome for cancer surgery patients 0 None
2012-01-31 IMUC president to present at Immunotherapeutics Partnering and Deal Making Conference 0 None
2012-01-31 Interim results from Allos Therapeutics' FOLOTYN and bexarotene Phase 1 combination study on CTCL 0 None
2012-01-31 ESC welcomes 'intriguing' study on heart failure 0 None
2012-01-31 Anti-HER2 dendritic cell vaccine shows promise against DCIS 2 1
2012-01-31 Juventas' JVS-100 Phase I heart failure trial meets primary safety endpoint 0 None
2012-01-30 AMAG completes enrollment in Feraheme Phase III program for iron-deficiency anemia 0 None
2012-01-27 Positive results from cisplatin plus radiation therapy trial on head and neck cancer 0 None
2012-01-27 Cancer Research UK opens first AT9283 trial to treat childhood leukaemia 0 None
2012-01-27 Two NIH clinical trials to evaluate treatments for out-of-hospital cardiac arrest 0 None
2012-01-27 Boehringer Ingelheim initiates two afatinib phase III trials in head and neck cancer 0 None
2012-01-25 Amorcyte commences enrollment in PreSERVE Phase 2 trial for acute myocardial infarction 0 None
2012-01-25 Lansoprazole increases risk of sore throats, respiratory problems in children with asthma 0 None
2012-01-25 Lansoprazole does not control asthma in children 0 None
2012-01-24 Aphios receives NIH's Phase II SBIR grant to develop APH-0703 for AD 0 None
2012-01-24 Gilead commences GS-7340 Phase 2 trial in HIV 0 None
2012-01-24 ImmunoCellular initiates enrollment in ICT-107 Phase II trial for GBM in 23 centers 0 None
2012-01-24 Dutasteride delays prostate cancer progression in men 0 None
2012-01-24 Baxter to commence second GAMMAGARD LIQUID Phase III trial in Alzheimer's 0 None
2012-01-23 Patient enrollment complete in Enlivex Phase I/II clinical trial for autoimmune diseases 0 None
2012-01-21 Adding oxaliplatin to adjuvant 5FU improves survival of patients with stage III colon cancer 0 None
2012-01-20 New data from Infinity saridegib and gemcitabine Phase 1b/2 combination trial on pancreatic cancer 0 None
2012-01-20 Positive preliminary data from Exelixis' cabozantinib phase 2 trial on HCC 0 None
2012-01-20 Banner Alzheimer's Institute presents results from Navidea AZD4694 study at 6th Annual HAI 0 None
2012-01-19 Experimental drug helps patients with advanced colon cancer 0 None
2012-01-19 Study demonstrates possibility of curing hepatitis C without use of interferon 0 None
2012-01-19 New combo drug helps suppress hepatitis C genotype 1 infection 0 None
2012-01-19 Rexahn receives approval to initiate RX-3117 Phase I trial in solid tumors 0 None
2012-01-19 Soligenix reports results from long-term stability studies of SGX204 anthrax vaccine 0 None
2012-01-19 Bristol-Myers Squibb agrees purchase of Inhibitex for $2.5Bn 0 None
2012-01-18 InflaRx completes IFX-1 phase I study on acute inflammatory diseases 0 None
2012-01-18 Pfizer and Medivation drop further testing of failed Alzheimer’s drug 0 None
2012-01-18 Cangrelor allows stent patients to be 'bridged' to cardiac surgery 0 None
2012-01-18 New combination treatment more effective in treating cutaneous T-Cell lymphoma 0 None
2012-01-18 Pfizer, Medivation report results from dimebon Phase 3 trial on AD 0 1
2012-01-18 Novelos initiates enrollment in HOT Phase 1b trial for advanced solid tumors 0 None
2012-01-17 Regorafenib lengthens lives of patients with metastatic colorectal cancer 0 None
2012-01-17 BJALCF receives $1 million in grants for 2012 Lung Cancer Research 0 None
2012-01-17 Pevion announces further data from clinical study of PEV7 therapeutic Candida vaccine 0 None
2012-01-17 Combination of lapatinib and trastuzumab more effective in treating HER2-positive breast cancer 0 4
2012-01-13 MYTHOS clinical trial demonstrates superiority of RenalGuard in reducing CIN 0 None
2012-01-13 Researchers publish first detailed figures that show risk of Rasilez and ACE inhibitors or ARBs 0 5
2012-01-13 Cabazitaxel with IMRT, androgen deprivation therapy may extend survival for prostate cancer patients 0 None
2012-01-12 Sangart commences MP4CO Phase 1b study in sickle cell disease 0 None
2012-01-11 Merrimack commences MM-151 Phase 1 trial in refractory advanced solid tumors 1 None
2012-01-11 Oramed files provisional patent application with USPTO for combination diabetes therapy 0 None
2012-01-11 Inherited breast and ovarian cancer drug trial re-launched in tablet form 0 None
2012-01-10 Starpharma receives FDA Special Protocol Assessment for bacterial vaginosis phase 3 1 None
2012-01-10 Study confirms safety and effectiveness of rAHF-PFM in managing hemophilia A 0 None
2012-01-10 Amylin outlines key strategic priorities for 2012 0 None
2012-01-09 Positive interim data from Idenix IDX184 12-week phase IIb trial on HCV 0 None
2012-01-09 Combination of GXR and psychostimulant safe and effective for children with ADHD 0 None
2012-01-09 Oxygen Biotherapeutics to commence study to determine efficacy of Dermacyte in relieving Histamine induced pruritus 0 None
2012-01-09 Idenix Pharmaceuticals makes progress with its HCV development pipeline 0 None
2012-01-09 Sangamo BioSciences starts Phase 2 clinical studies to develop functional cure for HIV/AIDS 0 5
2012-01-09 Presidio completes PPI-668 Phase 1a study on hepatitis C 0 None
2012-01-09 Pfizer, SFJ to conduct axitinib Phase 3 trial in renal cell carcinoma 0 None
2012-01-09 Enrollment complete in Diamyd Phase II study for type 1 diabetes 0 None
2012-01-09 Circadian initiates VGX-100 Phase 1 trial in advanced solid tumours 0 None
2012-01-08 Positive results from BioCryst's BCX4208 Phase 2b study on gout 0 None
2012-01-07 Lightlake intends to develop a treatment for premenstrual syndrome overeating 0 None
2012-01-07 Pearl Therapeutics completes two PT003 Phase 2b clinical studies on COPD 0 None
2012-01-07 FDA approval of raltegravir offers new weapon to treat HIV infection in children 0 None
2012-01-07 Alnylam files CTA with the U.K. MHRA to initiate ALN-TTR02 Phase I trial in ATTR 0 None
2012-01-07 Positive topline results from Civitas' CVT-301 Phase 1 trial on PD 0 None
2012-01-06 KAI commences enrollment in KAI-4169 second Phase 2 study for CKD-MBD 0 None
2012-01-06 Non-eosinophilic disease more prevalent in patients with mild-to-moderate asthma 0 None
2012-01-06 Varenicline may reduce smoking rates before people try to quit 0 None
2012-01-06 Isis announces results from ISIS-TTRRx Phase 1 study on TTR amyloidosis 0 None
2012-01-06 Wake Forest Baptist participates in novel brain tumor vaccine clinical trial 0 None
2012-01-06 Pfizer commences PF-05280602 Phase 1 trial in hemophilia A & B 0 None
2012-01-05 AstraZeneca plans to progress Targacept's AZD1446 as treatment for AD 0 None
2012-01-05 Baxter commences BAX 855 Phase I trial in hemophilia A 0 None
2012-01-05 RegeneRx's RGN-259 safe, well tolerated in patients with dry eye syndrome 0 None
2012-01-05 Hepatitis C vaccine succeeds in an early phase clinical trial 0 None
2012-01-05 Positive results from ProFibrix Phase II Fibrocaps clinical trial 0 None
2012-01-05 Probiodrug secures EUR 15M for clinical development of PQ912 0 None
2012-01-05 Daily doses of S-equol reduce hot flashes in postmenopausal women 0 None
2012-01-05 Celldex begins rindopepimut and Avastin Phase 2 combination trial in EGFRvIII-positive GB 0 None
2012-01-05 Bionomics, Ironwood partner to develop and commercialize novel anti-anxiety compound 0 None
2012-01-05 Positive results from Alkermes ALKS 5461 phase 1/2 study on MDD 0 None
2012-01-05 Investigational HSV vaccine shows promise against two genital herpes diseases 1 None
2012-01-05 Positive preliminary results from Alnylam's Phase I ALN-PCS trial on severe hypercholesterolemia 0 None
2012-01-05 Rilonacept appears safe and well-tolerated in patients with gout 0 None
2012-01-05 Arrowhead receives FDA IND approval for Adipotide obesity drug 2 5
2012-01-04 Viamet commences VT-464 Phase 1/2 trial in castration-refractory prostate cancer 0 None
2012-01-04 Veloxis commences LCP-Tacro Phase IIIb study in kidney transplant patients 0 None
2012-01-04 FDA grants orphan designation for AMT's hemophilia gene therapy program 0 None
2012-01-04 Pharmalink raises SEK 35 million to further advance Nefecon and Busulipo 0 None
2012-01-04 Antigen Express to move AE37 cancer vaccine into larger clinical trials 0 None
2012-01-04 BioMarin to initiate BMN-111 Phase 1 trial in achondroplasia 3 4.3
2012-01-04 BioLineRx commences BCM CE Mark registration trial for prevention of cardiac remodeling following AMI 0 None
2012-01-04 Arena, Eisai collaborate in response to FDA's lorcaserin Complete Response Letter 0 None
2012-01-04 Yakult Honsha commences perifosine Phase 1/2 trial for refractory advanced colorectal cancer in Japan 0 None
2012-01-04 Positive results from Can-Fite BioPharma's CF102 Phase 1/2 study on HCC 0 None
2012-01-03 Ampio completes enrollment phase of Australian Ampion In Knee trials 0 None
2012-01-03 Astellas, AVEO announce results of tivozanib and sorafenib comparison trial on RCC 0 None


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