Archived Medical News Stories

RSSArchived Drug Trial News Stories - June 2012

Date Title Comments Rating
2012-06-29 A.P. Pharma announces additional data from APF530 Phase 3 study on CINV 0 None
2012-06-29 Lexicon announces results from two initial trials of LX4211 for type 2 diabetes 0 None
2012-06-29 Drug trial participants should be better informed about benefits and side-effects of placebos 0 None
2012-06-29 Once-daily pill for HIV is a safe and effective alternative to traditional antiretroviral regimens 0 None
2012-06-29 New drug for Type 2 diabetes results in less hypoglycaemia, less weight gain and perhaps less cardiovascular risk for patients 0 None
2012-06-29 Medivir, Bristol-Myers Squibb to initiate TMC435 and daclatasvir phase II combination study in HCV 0 None
2012-06-29 Results from Access’ MuGard Phase 4 trial on oral mucositis 0 None
2012-06-28 LUMC oncologist presents survival data for brentuximab vedotin at 17th EHA Congress 0 None
2012-06-28 Pediatric Hodgkin lymphoma can be treated without radiation and intensive chemotherapy 0 None
2012-06-28 Full results from Derma Sciences’ DSC127 Phase 2 trial on diabetic foot ulcers 0 None
2012-06-28 Anthera announces results from blisibimod Phase 2b study on SLE 0 1.5
2012-06-27 Combination of radiation therapies effectively treat prostate cancer, lower chances of recurrence 0 None
2012-06-27 SIR/TAC combination more effective in preventing GVHD after allogeneic blood cell transplantation 0 None
2012-06-27 Top-line final data from Provectus’ PV-10 phase 2 trial on metastatic melanoma 0 None
2012-06-27 Vitamin D and calcium supplements could increase risk of kidney stones 0 3
2012-06-27 Sunshine Biopharma completes Adva-27a cytotoxicity study on multidrug-resistant lung cancer 0 None
2012-06-27 First clinical trial to test cardiac drug regimen for DMD 0 None
2012-06-27 RXi Pharmaceuticals initiates RXI-109 Phase 1 trial to reduce surgical scars 0 None
2012-06-27 BioSpecifics commences XIAFLEX Phase II trial in human lipoma 0 None
2012-06-26 Positive results from Antares Pharma's VIBEX MTX human factors usability study for RA 0 5
2012-06-26 Degludec reduces risk of nighttime low blood sugar in elderly diabetic adults 0 None
2012-06-26 Investigational parathyroid hormone replacement effectively treats hypoparathyroidism 2 None
2012-06-26 Clinical trial to examine functional benefits of combined therapy against stroke 0 None
2012-06-26 New drug better than chemotherapy for skin cancer patients 0 None
2012-06-26 Experimental medication increases muscle strength in cancer patients with low testosterone levels 0 None
2012-06-26 Combination of liraglutide and insulin controls blood sugar in obese adults with T1D 0 None
2012-06-26 Sitagliptin appears to reduce severity of reactive hypoglycemia 0 None
2012-06-26 Male hormonal contraceptives applied daily to the skin reduce sperm production 0 None
2012-06-26 KaloBios’ KB001 shows promise against Pa pneumonia 0 None
2012-06-26 Experimental medication helps overweight patients with diabetes shed pounds 0 None
2012-06-26 CytRx achieves key milestone in advancing tamibarotene Phase 2b trial for NSCLC 0 None
2012-06-26 Sinovac provides update on EV71 vaccine Phase III trial on HFMD 0 None
2012-06-25 Standard aspirin dose may not protect diabetics against blood clots 0 None
2012-06-25 Degludec effectively lowers blood glucose with lower risk for hypoglycemia 0 None
2012-06-25 NIH awards Sirnaomics SBIR grant for developing STP705 siRNA wound healing product 0 None
2012-06-25 Neuralstem commences dosing in NSI-189 Phase Ib trial for major depressive disorder 0 None
2012-06-25 Positive results from Lexicon’s LX4211 Phase 2b trial on type 2 diabetes 0 None
2012-06-25 Study reinforces importance of educating parents and other caregivers of children with food allergy 0 None
2012-06-25 Major weight loss an added benefit of testosterone replacement therapy for men 0 3.1
2012-06-23 Deferasirox reduces elevated iron levels in patients with myelodysplastic syndrome 0 5
2012-06-23 Genentech's Perjeta helps people with HER2-positive metastatic breast cancer live longer 1 None
2012-06-23 AbGenomics raises $11 million in current financing round 0 None
2012-06-22 Alexza resubmits ADASUVE NDA to U.S. FDA 0 None
2012-06-22 Shanghai Institutes of Preventative Medicine, Gentris sign MOU to advance personalized medicine 0 None
2012-06-22 Aeterna Zentaris announces perifosine Phase 1 trial on neuroblastoma 0 None
2012-06-22 Iroko announces results from diclofenac Phase 3 study on post-surgical pain 0 None
2012-06-22 Data from MAP Pharmaceuticals’ LEVADEX clinical studies to be presented at AHS meeting 0 None
2012-06-21 Study to test NAC and aspirin for people diagnosed with bipolar disorder 1 None
2012-06-21 Levodopa/carbidopa intestinal gel reduces 'off' time in people with advanced PD 0 5
2012-06-21 Omega-3 fatty acid supplements can reduce inflammation in overweight older adults 0 None
2012-06-20 Furiex initiates MuDelta Phase III studies in IBS-D 1 None
2012-06-19 Positive results from Zalicus Z944 Phase 1 SAD clinical study for chronic inflammatory pain 0 None
2012-06-19 e-Therapeutics commences enrollment in ETS2101 phase I trial for brain cancer 0 None
2012-06-19 Gilead's elvitegravir MAA for HIV-1 infection receives EMA validation 0 None
2012-06-19 New patent filed for VAC-3S, an immunotherapy for treating HIV infections 0 None
2012-06-19 Antiarrhythmic short-term treatment useful for some patients 0 None
2012-06-19 Five abstracts evaluating Abbott's LCIG presented at Parkinson's disease congress 0 None
2012-06-18 Positive interim data from Innate MIS416 Phase 1/2 clinical trial for chronic progressive MS 0 None
2012-06-18 CINJ commences enrollment in three-drug combination trial for breast cancer 0 None
2012-06-18 Infinity voluntarily stops saridegib Phase 2 trial for chondrosarcoma 0 None
2012-06-18 Cancer publishes Aeterna Zentaris' perifosine Phase 2 trials in RCC 0 None
2012-06-18 Updated data from ARIAD’s ponatinib pivotal trial on CML or Ph+ ALL 0 None
2012-06-18 DBV Technologies’ Viaskin safe and effective in treating children with peanut allergy 0 None
2012-06-18 UW initiates enrollment in tosedostat phase II combination study for AML, MDS 0 None
2012-06-18 Positive results from ERYTECH Pharma asparaginase Phase II trials on ALL 0 None
2012-06-18 Updated results from two clinical trials of Bruton's ibrutinib for CLL/SLL 0 None
2012-06-18 Impressive results from blinatumomab Phase 2 study on B-precursor ALL 0 None
2012-06-16 Promising results from single iron dose study for fatigue treatment in iron deficient women 0 None
2012-06-16 Combination of low-dose vitamin D and calcium does not reduce fracture risk in women 0 None
2012-06-16 St. Michael's to investigate new treatments for prevention of brain injury complications 0 None
2012-06-16 Large-scale trial of vaginal ring that releases anti-HIV drug announced at health summit in London 0 None
2012-06-16 Otsuka, Bristol-Myers Squibb announce six-year data from SPRYCEL Phase 3 trial on CP-CML 0 None
2012-06-16 Study finds no evidence to support an effect of THC on MS progression 0 None
2012-06-16 Civitas commences CVT-301 Phase 2a trial in Parkinson's disease 0 None
2012-06-16 Less expensive ARV combination just as effective for women in developing countries as costlier ARVs, study shows 0 None
2012-06-15 Sanofi’s insulin glargine delays progression from pre-diabetes to T2DM 0 None
2012-06-15 Changing guidelines threaten important HIV drug trial 0 None
2012-06-15 Positive top-line results from Teva’s GALA Phase III trial on RRMS 0 None
2012-06-15 TGen, Scottsdale Healthcare open INNO-206 Phase 2 trial for pancreatic cancer 0 None
2012-06-15 Antioxidant rhSOD reduces risk of blindness in extremely low gestational age newborns 0 None
2012-06-15 Dyax to discontinue ecallantide Phase 2 trial for ACE inhibitor-induced angioedema 0 None
2012-06-15 Theraclone Sciences commences TCN-202 Phase 1 trial in CMV infection 0 None
2012-06-15 Quest receives FDA clearance to initiate oregovomab Phase II trial in ovarian cancer 0 None
2012-06-14 Hay fever vaccine shows efficacy in phase IIa trial 0 None
2012-06-14 AB Science announces results from masitinib phase 2 study on MS 0 None
2012-06-14 Updated survival data from Takeda’s brentuximab vedotin Phase II trial on HL 0 None
2012-06-14 Cancers often recur after treatment with single drugs that “target” tumor cells’ genetic pathways 0 None
2012-06-14 IBBR, Sanaria to receive Phase II SBIR grant from NIAID for malaria vaccine 0 None
2012-06-14 Sabin initiates novel human hookworm vaccine Phase 1 clinical trial 0 None
2012-06-14 NEJM hails vismodegib as ‘the greatest advance in therapy yet seen’ for advanced BCC 0 None
2012-06-14 Ophthotech’s Fovista anti-PDGF combination therapy superior to Lucentis for wet AMD 0 5
2012-06-14 Azaya announces final results from ATI-1123 Phase I study on cancers 0 None
2012-06-14 EnVivo to present results from EVP-6124 Phase 2b trial on AD at AAIC 2012 0 None
2012-06-13 Investigational Insomnia Medicine from Merck improved patients’ ability to fall and stay asleep according to new phase III Data 0 None
2012-06-13 ChromaDex’s pTeroPure safe for human consumption 0 None
2012-06-13 New combination therapy can help improve cure rates for neuroblastoma 0 5
2012-06-13 Long-term insulin use does not increase risk of heart disease in people with diabetes 0 None
2012-06-13 VaxInnate commences VAX161 Phase I trial in pandemic avian influenza 0 None
2012-06-13 Acorda commences AMPYRA clinical study for post-stoke deficits 0 3
2012-06-12 Almased helps patients with type 2 diabetes lose weight, gain better sugar control 0 None
2012-06-12 Initial trial results from KYTHERA’s second of two Phase III trials with ATX-101 0 None
2012-06-12 Individuals on statins more likely to experience fatigue with exertion 0 None
2012-06-11 Theramine may reduce chronic low back pain 0 4
2012-06-11 FDA accepts Avanir IND for AVP-923 to treat agitation in patients with AD 0 None
2012-06-11 Positive results from Cara’s CR845 Phase II study on acute post-operative pain 0 None
2012-06-11 BioSante to initiate two new LibiGel Phase III efficacy trials in FSD, HSDD 0 None
2012-06-11 Ampio’s CRO completes Optina clinical trial for DME 0 None
2012-06-11 Dapagliflozin more effective than sitagliptin for adult patients with type 2 diabetes 0 None
2012-06-11 Zafgen announces new data from two Phase 1 studies of beloranib on obesity 0 None
2012-06-11 Sanofi’s Lantus more effective than sitagliptin for people with type 2 diabetes 0 None
2012-06-11 Pre-operative aspirin therapy may reduce risk of acute kidney failure after CABG surgery 0 None
2012-06-11 Cebix announces data from Ersatta Phase 1 study on type 1 diabetes 0 None
2012-06-11 Amylin announces results from SYMLIN clinical studies on type 2 or 1 diabetes 0 5
2012-06-11 Amylin, Alkermes announce results from BYDUREON clinical study on type 2 diabetes 0 None
2012-06-11 Lilly, Boehringer Ingelheim announce results from linagliptin Phase III trial on T2D 0 None
2012-06-11 Incyte, Lilly announce 12-week results from baricitinib Phase IIb study on RA 0 None
2012-06-10 Lexicon presents six posters on LX4211 at ADA meeting 0 None
2012-06-08 CSL Behring rIX-FP granted Orphan Drug Designation to treat hemophilia B 0 None
2012-06-08 Positive results from Amgen Sensipar/Mimpara Phase 3 trial for HPT, CKD 0 None
2012-06-08 Large-scale randomized treatment study on adrenocortical cancer 0 None
2012-06-08 Erivedge drug shows promise against advanced basal cell carcinoma 0 None
2012-06-08 Data from abatacept versus adalimumab Phase IIIb comparison study on RA 0 None
2012-06-08 Experimental drug tested against multi-drug resistant TB 0 None
2012-06-08 Banyan, Amarantus complete collaboration agreement related to TBI development program 0 None
2012-06-08 Sorrento receives $300,000 STTR grant to develop novel therapeutics against Staph infections 0 None
2012-06-08 NCI presents long-term outcomes from BiovaxID lymphoma vaccine Phase II trial at ASCO 2012 2 None
2012-06-08 MGH, HSG to conduct PBT2 clinical trial in Huntington's disease 0 4
2012-06-07 Enrollment complete in Advaxis’ ADXS-HPV Phase 2 study on CIN 2/3 0 None
2012-06-07 Clinical study shows positive effects of CAD106 vaccine against AD 0 None
2012-06-07 Biologic treatments reduce mortality risk in patients with rheumatoid arthritis 0 None
2012-06-07 Dengue fever vaccine 'may be in sight,' Reuters reports 0 None
2012-06-07 Clinical study demonstrates effectiveness of vismodegib in treating BCNS 0 None
2012-06-07 Savient announces results from KRYSTEXXA Phase III trials on gout-related kidney disease 0 None
2012-06-07 Debiopharm announces results from Debio 0932 Phase I study on cancer 0 5
2012-06-07 ADACTA trial: Tocilizumab more effective than adalimumab in treating RA 0 2
2012-06-06 AB Science announces data from development program of masitinib in GIST 0 None
2012-06-06 STELARA effectively reduces signs and symptoms of active psoriatic arthritis 0 None
2012-06-06 PhaseBio raises $48.4M in Series B financing 0 None
2012-06-06 Abbott announces results from HUMIRA Phase 3 study on axSpA 0 None
2012-06-06 Cardio-protective drug during cancer treatment may prevent heart damage in children 0 None
2012-06-06 Aeterna Zentaris announces results from perifosine Phase 1 trial on multiple myeloma 0 None
2012-06-06 Bayer announces updated data from radium-223 dichloride Phase III trial on CRPC 0 None
2012-06-06 Abbott commences elagolix Phase 3 trial in endometriosis 0 None
2012-06-06 New immune response data from Generex’s AE37 Phase II trial on breast cancer 0 None
2012-06-06 Positive updated interim data from Exelixis’ cabozantinib phase 2 trial on CRPC 0 None
2012-06-05 Lilly announces final results from ALIMTA Phase III study on NSCLC 0 4
2012-06-05 Three-drug regimen provides rapid, durable responses for multiple myeloma 0 None
2012-06-05 Soy protein may not enhance overall cognitive ability in women 0 None
2012-06-05 T-DM1 better than standard therapy in controlling breast cancer 0 None
2012-06-05 BioInvent, ThromboGenics announce results from TB-402 Phase IIb trial on VTE 0 None
2012-06-05 New PD-1 blocking antibody shows promise against advanced kidney cancer 0 3
2012-06-05 D-cycloserine may increase response to PTSD psychotherapy 0 None
2012-06-05 Updated results from three trials of Bruton's ibrutinib for treatment of CLL/SLL 0 5
2012-06-05 Parkinson’s vaccine: worldwide first clinical trial begins 0 None
2012-06-05 Cannabinoid therapy helps provide effective analgesia for cancer patients with pain 0 None
2012-06-05 Jennerex announces data from JX-594 clinical studies on cancer 0 None
2012-06-05 Esperance presents results from EP-100 Phase 1 study on solid tumors at ASCO annual meeting 0 None
2012-06-05 Results from Celgene’s ABRAXANE plus gemcitabine clinical study on resectable pancreatic cancer 0 None
2012-06-05 Ipsen, Active Biotech present OS data from tasquinimod Phase II study on CRPC at ASCO 2012 0 None
2012-06-05 Alnylam announces results from ALN-VSP Phase I study on liver cancers 0 2.2
2012-06-05 High doses of ginseng more effectively reduce cancer-related fatigue in patients 0 None
2012-06-05 Senesco reports on the progress of SNS01-T Phase 1b/2a study for multiple myeloma 0 None
2012-06-05 Exelixis reports data from cabozantinib phase 3 trial on MTC 0 None
2012-06-05 Promising data from Array BioPharma’s MEK162 Phase 2 trial on BRAF and NRAS mutant melanoma 0 None
2012-06-05 OncoGenex announces data from OGX-427 Phase 2 study on mCRPC 0 None
2012-06-05 Positive results from BioSpecifics’ XIAFLEX Phase III clinical program on Peyronie's disease 0 3
2012-06-05 Preliminary results from Incyte’s INCB024360 Phase I trial on solid tumors 0 None
2012-06-05 Antisense Pharma presents data from trabedersen Phase I/II cancer study at ASCO 2012 0 5
2012-06-05 Seattle Genetics, Agensys announce interim data from ASG-5ME phase I trial on CRPC 0 None
2012-06-05 Takeda announces updated results from orteronel phase 2 study on nmCRPC 0 None
2012-06-05 Ambit, Astellas commence quizartinib Phase 2b trial in relapsed/refractory AML 0 None
2012-06-04 Adamas to present update on Nurelin program at CHI Targeting Parkinson's Disease Symposium 0 None
2012-06-04 Aeterna Zentaris announces results from perifosine Phase 3 trial on colorectal cancer 0 None
2012-06-04 Polynoma initiates POL 103A Phase III trial in melanoma 0 None
2012-06-04 ViroPharma initiates maribavir Phase 2 program for CMV infections 0 None
2012-06-04 Advaxis to update preliminary data on ADXS-HPV Phase 2 trial for cervical cancer 0 None
2012-06-04 Exelixis reports positive interim data from cabozantinib phase 2 trial on HCC 0 None
2012-06-04 Onyx announces data from regorafenib Phase 3 trial on GIST 0 None
2012-06-04 Oncothyreon announces data from two clinical trials of PX-866 at ASCO meeting 0 None
2012-06-04 New data from ImmunoGen’s SAR3419 Phase I study on CD19+ NHL 0 None
2012-06-04 New data from OncoMed’s OMP-59R5 Phase I study on advanced solid tumors 0 None
2012-06-04 ImmunoGen reports data from T-DM1 Phase III trial on HER2-positive metastatic breast cancer 0 None
2012-06-04 Many men with metastatic prostate cancer live longer on continuous hormone therapy 0 None
2012-06-04 Positive results from Auxilium’s XIAFLEX phase III studies on Peyronie's disease 0 4.8
2012-06-04 Study shows valuable role of Mammostrat in assessing ER+ postmenopausal breast cancer patients 0 None
2012-06-04 Duloxetine drug reduces painful chemotherapy-induced peripheral neuropathy in majority of patients 0 None
2012-06-04 Results from Puma’s PB272 Phase I combination trial on metastatic HER-2 positive breast cancer 0 None
2012-06-04 Data from several clinical trials of ADCETRIS to be presented at ASCO annual meeting 0 None
2012-06-04 Results from Janssen's ZYTIGA plus prednisone Phase 3 study on mCRPC 0 5
2012-06-04 Genentech’s T-DM1 Phase III study on HER2-positive mBC meets primary endpoint 0 None
2012-06-04 Final results from ArQule and Daiichi Sankyo’s tivantinib phase 2 trial on HCC 0 None
2012-06-04 Roche to initiate three studies with T-DM1 for early stage HER2-positive breast cancer 0 None
2012-06-04 Favorable results from CytRx’s INNO-206 Phase 1b/2 trial on soft tissue sarcomas 0 None
2012-06-04 Interim results from Bristol-Myers Squibb’s BMS-936558 Phase 1 study on NSCLC, MM and RCC 0 None
2012-06-02 ZYTIGA Phase 3 study for metastatic prostate cancer presented at 48th ASCO 0 4.3
2012-06-02 Study supports wider testing for immune-based therapies to treat advanced non-small cell lung cancer 0 None
2012-06-02 Lapatinib-pazopanib combination therapy not beneficial for patients with inflammatory breast cancer 0 None
2012-06-02 Clinical trial to examine effectiveness of combined vaccine and hormone treatment for prostate cancer 0 None
2012-06-02 Beneficial design element in sunitinib phase III clinical trial for gastrointestinal stromal tumors 0 None
2012-06-02 Two pharma companies plan international trials into targeted cancer treatments in the UK 0 None
2012-06-02 LDK378 compound well-tolerated in patients with ALK+ NSCLC 0 None
2012-06-02 New medication proves effective in slowing the spread of metastatic prostate cancer 0 None
2012-06-02 Liver metastases predicts shorter overall survival in men with mCRPC 0 None
2012-06-02 Lilly, Kowa announce results from PREVAIL U.S. study 0 None
2012-06-01 Results from A.P. Pharma’s APF530 Phase 3 trial on CINV 0 None
2012-06-01 Beta-carotene safe to use during radiation therapy for prostate cancer 0 None
2012-06-01 ImmunoCellular to present new data from ICT-107 Phase I trial on GBM 0 None
2012-06-01 NAC reduces irritability in children with autism 0 4
2012-06-01 Top-line results from Genzyme’s teriflunomide Phase III trial on MS 0 None
2012-06-01 NCI, Tau Therapeutics open enrollment in mibefradil Phase Ib glioma trial 0 None
2012-06-01 Oncothyreon commences PX-866 and vemurafenib Phase 1/2 combination trial for melanoma 0 None
2012-06-01 RXi’s RXI-109 IND receives FDA clearance to proceed into clinical trials 0 None
2012-06-01 Omeros commences planned PK substudy in Phase 3 clinical program of OMS302 0 None


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