Contains the active ingredient metoprolol (as metoprolol tartrate)
Consumer Medicine Information
NOTICE: This Consumer Medicine Information (CMI) is intended for persons
living in Australia. This page contains answers to some common
. It does
not contain all the information that is known about
. It does not take the
place of talking to your doctor or pharmacist. All medicines have risks
and benefits. Your doctor has weighed the risk of you using this medicine
against the benefits he/she expects it will have for you. If you have
any concerns about using this medicine, ask your doctor or pharmacist.
Bookmark or print this page, you may need to read it again.
What this medicine is used for
The name of your medicine is Chemmart Metoprolol. It contains the active ingredient metoprolol.
It is used to:
lower higher blood pressure (hypertension)
prevent angina (a type of chest pain)
treat or prevent heart attacks, or reduce the risk of heart complications following a heart attack (myocardial infarction)
Ask your doctor if you have any questions about why this medicine has been prescribed for you. Your doctor may have prescribed
this medicine for another reason.
This medicine is available only with a doctor's prescription.
How it works
Metoprolol belongs to a group of medicines called beta-blockers.
It works by affecting the body's response to some nerve impulses, especially in the heart. As a result, it decreases the heart's
need for blood and oxygen and therefore reduces the amount of work the heart has to do. It also widens the blood vessels in
the body, causing blood pressure to fall.
There is no evidence that this medicine is addictive.
Use in children
This medicine should not be used in children.
Before you take this medicine
When you must not take it
Do not take this medicine if:
You have or have had any of the following:
sudden loss of consciousness
asthma, wheezing, difficulty breathing or other severe lung problems
allergic problems, including hay fever
a very slow heart beat, less than 45 to 50 beats per minute
low blood pressure
a severe blood vessel disorder causing poor circulation in the arms and legs
severe drop in blood pressure, dizziness, fast heart beat, rapid and shallow breathing, cold clammy skin
phaeochromocytoma (a rare tumour of the adrenal gland) which is not already being treated with other medicines
sudden and oppressive chest pain, sign of heart attack
irregular heart beat
swollen ankles and/or tiredness due to heart disease or certain other heart conditions
poor blood circulation in your limbs (for example, very cold, pale hands or feet, or pain in your leg muscles when you walk).
undergo an operation where an anesthetic is used during treatment with respiratory diseases such as asthma
oculomucocutaneous syndrome (signs include severe conjunctivitis and skin rash and ear infection)
sensitivity to any other beta blocker medicine.
You are intolerant or allergic to lactose.
You are hypersensitive to, or have had an allergic reaction to, metoprolol or any of the ingredients listed at the end of
Symptoms of an allergic reaction may include: cough, shortness of breath, wheezing or difficulty breathing; swelling of the
face, lips, tongue, throat or other parts of the body; rash, itching or hives on the skin; fainting; or hay fever-like symptoms.
If you think you are having an allergic reaction, do not take any more of the medicine and contact your doctor immediately
or go to the Accident and Emergency department at the nearest hospital.
The expiry date (EXP) printed on the pack has passed.
The packaging is torn, shows signs of tampering or it does not look quite right.
Before you start to take it
Before you start taking this medicine, tell your doctor if:
You have allergies to:
any other medicines
any other substances, such as foods, preservatives or dyes.
bee or wasp stings.
You have or have had any medical conditions, especially the following:
chest pain when you are at rest or certain types of angina, such as Prinzmetal angina or variant angina
kidney or liver problems
an overactive thyroid gland.
You are currently pregnant or you plan to become pregnant. Do not take this medicine whilst pregnant until you and your doctor
have discussed the risks and benefits involved.
You are currently breastfeeding or you plan to breast-feed. Do not take this medicine whilst breastfeeding until you and your
doctor have discussed the risks and benefits involved.
You have recently been vaccinated or plan to get a vaccination.
You are planning to have surgery or an anaesthetic.
You are currently receiving or are planning to receive dental treatment.
You are taking or are planning to take any other medicines. This includes vitamins and supplements that are available from
your pharmacy, supermarket or health food shop.
Some medicines may interact with metoprolol. These include:
other beta-blocker medicines
other medicines used to treat high blood pressure such as calcium channel blockers and clonidine
some medicines used to treat angina
adrenaline or similar substances, which are often found in eye or nose drops, or in some cough and cold medicines
other medicines used to treat irregular heart beat (arrhythmias)
medicines for diabetes
quanethidine, a medicine used to treat certain heart conditions
some local and general anaesthetics used during surgery
monoamine-oxidase inhibitor (MAOI) medicines
warfarin, a medicine used to prevent blood clots
non-steroidal anti-inflammatory drugs such as COX-2 inhibitors to relieve pain or inflammation
cimetidine, a medicine for stomach ulcers
some antibiotics (e.g. rifampicin)
some antivirals (e.g. ritonavir)
some antihistamines (e.g. diphenhydramine)
some antidepressant medications (e.g. fluoxetine, paroxetine or bupropion)
some antifungals (e.g. terbinafine)
ergot alkaloids, a class of medicines used in the prevention and treatment of migraine headaches
dipyridamole, a medicine use to reduce the risk of blood clots.
If you are taking any of these you may need a different dose or you may need to take different medicines.
Other medicines not listed above may also interact with metoprolol.
How to take this medicine
Follow carefully all directions given to you by your doctor. Their instructions may be different to the information in this
How much to take
Your doctor will tell you how much of this medicine you should take. This will depend on your condition and whether you are
taking any other medicines.
Do not stop taking your medicine or change your dosage without first checking with your doctor.
High blood pressure (hypertension):
The usual dose is from 50 mg to 200 mg each day, either as a single dose or divided into two doses.
The usual dose is from 100 mg to 300 mg each day, divided into two or three doses.
Heart attack (myocardial infarction):
The usual dose is 200 mg each day, divided into two doses.
To prevent migraine:
The usual dose is from 100 mg to 150 mg each day, divided into two doses (morning and evening).
How to take it
Swallow the tablet(s) with a full glass of water.
If you need to break the tablet, hold it with both hands and snap it along break line.
When to take it
Take this medicine at the same time each day. Taking it at the same time each day will have the best effect and will also
help you remember when to take it.
It does not matter if you take it before, with or after food.
How long to take it for
Continue taking your medicine for as long as your doctor tells you.
Make sure you have enough to last over weekends and holidays.
If you forget to take it
If it is almost time to take your next dose, skip the missed dose and take your next dose at the usual time. Otherwise, take
it as soon as you remember and then go back to taking your medicine as you would normally.
Do not take a double dose to make up for missed doses.
This may increase the chance of you experiencing side effects.
If you have trouble remembering to take your medicine, ask your pharmacist for some hints to help you remember.
If you take too much (overdose)
If you think that you or anyone else may have taken too much of this medicine, immediately telephone your doctor or the Poisons
Information Centre (Tel: 13 11 26 in Australia) for advice. Alternatively, go to the Accident and Emergency department at
your nearest hospital.
Do this even if there are no signs of discomfort or poisoning. You may need urgent medical attention.
Symptoms of an overdose may include feeling sick and vomiting, bluish skin and nails, very low blood pressure, slow heart
beat, difficulty breathing, fainting, convulsions (fits) or coma.
While you are taking this medicine
Things you must do
Tell your doctor that you are taking this medicine if:
you are about to be started on any new medicine
you plan to have any vaccinations or immunisations
you are pregnant or are planning to become pregnant
you are breastfeeding or are planning to breast-feed
you are about to have any blood tests
you are going to have surgery or an anaesthetic or are going into hospital
you have an allergic reaction to a food, another medicine or an insect sting while you are taking this medicine.
If you are being treated for diabetes, make sure you check your blood sugar level regularly and report any changes to your
Metoprolol may change how well your diabetes is controlled. It may also cover up some of the symptoms of low blood sugar,
called hypoglycaemia, such as fast heart beat. It may make low blood sugar last longer. Your doses of diabetic medicines may
need to change.
Your doctor may occasionally do tests to make sure the medicine is working and to prevent side effects. Go to your doctor
regularly for a check-up.
Tell any other doctors, dentists and pharmacists who are treating you that you take this medicine.
Things you must not do
Give this medicine to anyone else, even if their symptoms seem similar to yours.
Take your medicine to treat any other condition unless your doctor tells you to.
Stop taking your medicine, or change the dosage, without first checking with your doctor.
Things to be careful of
Be careful when driving or operating machinery until you know how this medicine affects you.
As with other beta-blocker medicines, this medicine may cause dizziness, light-headedness or decreased alertness in some people.
If you have any of these symptoms, do not drive or do anything else that could be dangerous. If these symptoms do not go away,
talk to your doctor.
Be careful to dress warmly during cold weather, especially if you will be outside for a long time.
Like other beta-blocker medicines, this medicine may make you more sensitive to cold temperatures, especially if you have
problems with your blood circulation. These medicines tend to decrease blood circulation in the skin, fingers and toes.
Possible side effects
Tell your doctor as soon as possible if you do not feel well while you are taking metoprolol or if you have any questions
Do not be alarmed by the following lists of side effects. You may not experience any of them. All medicines can have side
effects. Sometimes they are serious but most of the time they are not.
Tell your doctor if you notice any of the following. Mostly, these are mild:
tiredness, drowsiness, decreased alertness
dizziness, spinning sensation (vertigo), light-headedness or fainting
headache or other aches and pains
difficulty sleeping, nightmares
depression or other changes in mood
confusion or loss of memory
stomach ache or upset, nausea (feeling sick) or vomiting
diarrhoea or constipation
dry or irritated eyes, blurred
buzzing or ringing in the ears, or
other difficulty hearing
runny or blocked nose
problems with sexual function
numbness, tingling in the extremities
worsening of psoriasis
muscle cramps or painful joints
a tingling sensation
abnormal triglycerides or cholesterol values, or liver function tests
sleepiness during the day or troubled sleep
diarrhoea or constipation.
If you experience any of the following, stop taking your medicine and contact your doctor immediately or go to the Accident
and Emergency department at your nearest hospital.
These side effects could be serious and you may need urgent medical attention or hospitalisation:
chest tightness, wheezing, rattly breathing
shortness of breath, sometimes with tiredness, weakness or reduced ability to exercise
swelling of the feet or legs due to fluid build-up
coldness, burning, numbness or pain in arms and legs
pain behind the breastbone (different from angina)
changes in heart rate (fast, slow, irregular)
yellowing of the skin or eyes (jaundice), sometimes with pain in the abdomen
constant "flu-like" symptoms (chills, fever, sore throat, aching joints, swollen glands, tiredness or lack of energy)
unusual bleeding or bruising
skin reactions (rash, itching, worsening of psoriasis)
symptoms of sunburn (redness, itching, swelling, blistering) that happen much more quickly than normal
abnormal thinking or hallucinations (seeing or hearing things that are not there)
breathlessness, difficulty breathing when lying down, swelling of the feet or legs, signs of heart disorders.
Other side effects not listed above may occur in some patients.
If you think you are having an allergic reaction to metoprolol, do not take any more of this medicine and tell your doctor
immediately or go to the Accident and Emergency department at your nearest hospital.
Symptoms of an allergic reaction may include some or all of the following:
cough, shortness of breath, wheezing or difficulty breathing
swelling of the face, lips, tongue, throat or other parts of the body
rash, itching or hives on the skin
hay fever-like symptoms.
Storage and disposal
Keep your medicine in its original packaging until it is time to take it.
If you take your medicine out of its original packaging it may not keep well.
Keep your medicine in a cool dry place where the temperature will stay below 25°C. Protect from light.
Do not store your medicine, or any other medicine, in the bathroom or near a sink. Do not leave it on a window sill or in
the car. Heat and dampness can destroy some medicines.
Keep this medicine where children cannot reach it.
A locked cupboard at least one-and-a-half metres above the ground is a good place to store medicines.
If your doctor tells you to stop taking this medicine or it has passed its expiry date, your pharmacist can dispose of the
remaining medicine safely.
What Chemmart Metoprolol looks like
White, round tablets, scored on one side.
Available in blister packs of 100 tablets.
White, round tablets, scored on one side.
Available in blister packs of 60 tablets.
* Not all strengths, pack types and/or pack sizes may be available.
Each tablet contains 50 or 100 mg of metoprolol as the active ingredient.
It also contains the following inactive ingredients:
colloidal anhydrous silica
calcium hydrogen phosphate
This medicine is gluten-free, sucrose-free, tartrazine-free and free of other azo dyes.
Australian Registration Numbers
Chemmart Metoprolol 50 mg tablets (blisters): AUST R 78853.
Chemmart Metoprolol 100 mg tablets (blisters): AUST R 78854.
Apotex Pty Ltd
16 Giffnock Avenue
Macquarie Park NSW 2113
Chemmart is a registered trademark of Symbion Pty Ltd.
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