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Marcain and Marcain Spinal Heavy

Bupivacaine hydrochloride
Consumer Product Information
 
 

NOTICE: This Consumer Medicine Information (CMI) is intended for persons living in Australia. This page contains answers to some common questions about Marcain and Marcain Spinal Heavy. It does not contain all the information that is known about Marcain and Marcain Spinal Heavy. It does not take the place of talking to your doctor or pharmacist. All medicines have risks and benefits. Your doctor has weighed the risk of you using this medicine against the benefits he/she expects it will have for you. If you have any concerns about using this medicine, ask your doctor or pharmacist. Bookmark or print this page, you may need to read it again.

What MARCAIN 0.5% and MARCAIN SPINAL 0.5% HEAVY are for

Marcain 0.5% and Marcain Spinal 0.5% Heavy are used to prevent or relieve pain, before surgery of the lower abdomen and lower limbs. They will not put you to sleep.
Marcain 0.5% and Marcain Spinal 0.5% Heavy can also be used to make childbirth less painful.
Marcain 0.5% and Marcain Spinal 0.5% Heavy belong to a group of medicines called spinal local anaesthetics. They are injected into the spinal fluid where they make the nerves unable to pass messages to the brain.
Depending on the amount used, Marcain 0.5% and Marcain Spinal 0.5% Heavy will either totally stop pain or will cause a partial loss of feeling.
Your doctor will have explained why you are being treated with Marcain 0.5% or Marcain Spinal 0.5% Heavy and told you what dose you will be given.
Follow all directions given to you by your doctor carefully.
They may differ from the information contained in this leaflet.
Your doctor may prescribe this medicine for another use. Ask your doctor if you want more information.
Marcain 0.5% and Marcain Spinal 0.5% Heavy are not addictive.

Before you are given MARCAIN 0.5% or MARCAIN SPINAL 0.5% HEAVY

When you must not have it

Do not use Marcain 0.5% or Marcain Spinal 0.5% Heavy if you are pregnant or breastfeeding unless your doctor says so. Ask your doctor about the risks and benefits involved.
We do not know if it is safe for you to be given it while you are pregnant. They may affect your baby if you take it early in pregnancy or in the last weeks before your baby is due. However, they can be used during childbirth.
Your baby can take in very small amounts of Marcain 0.5% or Marcain Spinal 0.5% Heavy from breast milk if breastfeeding.
Marcain 0.5% and Marcain Spinal 0.5% Heavy will only be used if the solution is clear, the package is undamaged and the use by (expiry) date marked on the pack has not been passed.
They may have no effect at all, or worse, an entirely unexpected effect if you are given them after the expiry date.

Before you are given it

You must tell your doctor if:

1. you have any allergies to

any ingredients listed at the end of this leaflet
other local anaesthetics eg. lignocaine
any other substances
If you have an allergic reaction, you may get a skin rash, hay fever or difficulty breathing.

2. you have any of these medical conditions

problems with your blood pressure or circulation
blood poisoning
problems with the clotting of your blood
nerve or heart problems
liver or kidney problems
malignant hyperthermia
diseases of the brain or spine
some types of back problems
It may not be safe for you to be given Marcain 0.5% or Marcain Spinal 0.5% Heavy if you have any of these conditions.

Taking other medicines

Tell your doctor if you are taking any other medicines, including medicines that you buy at the chemist, supermarket or health food shop.
These medicines may affect the way Marcain 0.5% or Marcain Spinal 0.5% Heavy work.
Your doctor or pharmacist can tell you what to do if you are taking any of these medicines.
If you have not told your doctor about any of these things, tell them before you are given any Marcain 0.5% or Marcain Spinal 0.5% Heavy.

How MARCAIN 0.5% and MARCAIN SPINAL 0.5% HEAVY are given

Marcain 0.5% or Marcain Spinal 0.5% Heavy will be injected by your doctor into the spinal canal, through a space between the bones in your lower back. This is called a SPINAL injection and it will result in a feeling of numbness in your lower body, in an area that may seem unrelated to the site of injection.
Marcain 0.5% and Marcain Spinal 0.5% Heavy should not be injected directly into the blood.
The dosage you will be given will depend on your body size, age and the type of pain relief required. Your doctor will have had a lot of experience injecting Marcain 0.5% and Marcain Spinal 0.5% Heavy or other local anaesthetics and will choose the best dose for you.
They will be willing to discuss this decision with you.

Overdose

The doctor giving you Marcain 0.5% or Marcain Spinal 0.5% Heavy will be experienced in the use of spinal local anaesthetics, so it is unlikely that you will be given an overdose.
However, if you are particularly sensitive to Marcain 0.5% or Marcain Spinal 0.5% Heavy, or the dose is accidently injected directly into your blood, you may develop problems for a short time with your sight or hearing. You may get a numb feeling in or around the mouth, feel dizzy or stiff, or have twitchy muscles.
Whenever you are given Marcain 0.5% or Marcain Spinal 0.5% Heavy, equipment will be available to care for you if an overdose happens.

While you are being given it

Things to be careful of

Be careful driving or operating machinery after you have been given Marcain 0.5% or Marcain Spinal 0.5% Heavy.
You may be drowsy and your reflexes may be slow.
Do not drink alcohol while you are being given Marcain 0.5% or Marcain Spinal 0.5% Heavy.
If you drink alcohol while you are being given Marcain 0.5% or Marcain Spinal 0.5% Heavy your blood pressure may drop, making you feel dizzy and faint.
Please talk to your doctor or pharmacist about these possibilities if you think they may bother you.

Side effects

Tell your doctor or nurse as soon as possible if you do not feel well while you are being given Marcain 0.5% or Marcain Spinal 0.5% Heavy.
Marcain 0.5% and Marcain Spinal 0.5% Heavy will prevent or relieve pain in most people, but they may have unwanted side-effects. All medicines can have side effects. Sometimes they are serious, most of the time they are not. You may need medical treatment if you get some of the side effects.
Ask your doctor, nurse or pharmacist to answer any questions you may have.
Tell your doctor or nurse if you notice any of the following and they worry you:
nervousness
dizziness
blurred vision
drowsiness
ringing in the ears
numbness
feeling strange (disoriented)
nausea
vomiting
These are all mild side effects of Marcain 0.5% and Marcain Spinal 0.5% Heavy.
After a spinal injection you may develop a headache or backache which is not always related to the medicine used. These can, on rare occasions, last for some months after the injection is given.
If Marcain 0.5% or Marcain Spinal 0.5% Heavy is given wrongly, or you are very sensitive to it, it sometimes causes
fits
unconsciousness
breathing problems
low blood pressure
slow heart beat
collapse
These are all serious side effects. You may need urgent medical attention
Some people may get other side effects while being given Marcain 0.5% or Marcain Spinal 0.5% Heavy.
Tell your doctor if you notice anything else that is making you feel unwell.

After using it

Storage

Marcain 0.5% or Marcain Spinal 0.5% Heavy will be stored by your doctor or pharmacist under the recommended conditions.
It should be kept in a cool dry place where the temperature stays below 25 degrees C.

Disposal

Any Marcain 0.5% or Marcain Spinal 0.5% Heavy which is not used, will be disposed of in a safe manner by your doctor or pharmacist.

Product description

Each Marcain 0.5% Injection contains bupivacaine hydrochloride 0.5% (5mg/mL) as the active ingredient,
plus
Sodium chloride
Hydrochloric acid or sodium hydroxide for pH adjustment
Water for Injections
Each Marcain Spinal 0.5% Heavy Injection contains bupivacaine hydrochloride 0.5% w/v (5mg/ml) as the active ingredient,
plus
Glucose 8% w/v (80mg/mL)
Sodium hydroxide for pH adjustment
Water for Injections
The inclusion of glucose in Marcain Spinal 0.5% Heavy means that it will move along your spinal canal with gravity, depending on which way your body is tilted.
Marcain 0.5% and Marcain Spinal 0.5% Heavy are available as 4mL glass ampoules in Sterile AstraZeneca Theatre Pack™ in packs of 5.

Manufacturer

AstraZeneca Pty Ltd
ABN 54 009 682 311
Alma Road
NORTH RYDE NSW 2113
Australian Registration Number
MARCAIN 0.5% (SPINAL)
glass ampoules 21016
MARCAIN SPINAL 0.5% HEAVY
glass ampoules 11941
This leaflet was prepared in April 2004
Marcain and Sterile AstraZeneca Theatre Pack are trade marks of the AstraZeneca group of companies