抗氧剂：亲氧化剂活动

由 Ananya Mandal， MD 博士

减少也导致多种易反应的氧气种类和自由基活动的这个亲氧化剂或氧化重点的抗氧剂有暗边。

例如，维生素 C 或作为抗氧剂的抗坏血酸，当它减少也时氧化物质例如过氧化氢减少通过 Fenton 回应生成自由基的金属离子。

抗氧剂的抗氧剂和亲氧化剂活动的相对重要性是重要。当然维生素 C 比亲氧化剂活动有抗氧化活性。

Fenton 回应

Fenton 回应是如下：

2 Fe³⁺ + 抗坏血酸→ 2 Fe²⁺ + Dehydroascorbate

2 Fe²⁺ + 2 HO₂₂ → 2 Fe³⁺ + 2 OH· + 2 OH⁻

当抗氧化酵素从生理抗氧化活性时偏离他们在细胞阻力可能安排严重作用对氧化剂诱发损坏对脱氧核糖核酸和细胞杀害。 Fenton 回应对脱氧核糖核酸故障负责导致在氧化重点下。

一种有利或一种不利的蜂窝电话回应的发展由营养素的取决于营养素的抗氧剂或亲氧化剂特性。这取决于这个产品或蜂窝电话氧气环境。

营养素例如类胡萝卜素、维生素 E 或者抗坏血酸衍生商品将展示抗氧剂或亲氧化剂典型根据单个分子的氧化还原电位和细胞的无机化学。

作为的多数抗氧化营养素 chemopreventives 防止额外的细胞增长。当一个不相应的亲氧化剂活动在正常细胞时开发，被生成的易反应的氧气代谢产物可能损坏脱氧核糖核酸和蜂窝电话膜。因而必须考虑每营养素易变的氧化还原的字符根据细胞外和细胞内 microoxygen 环境。

几个动物和人力研究显示了饮食抗氧剂的有利和负面影响。

复核在 4月 Cashin-Garbutt 前， BA Hons (Cantab)

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