Psoriasis fotokemoterapi

Psoralen dan sinar ultraviolet A fototerapi (PUVA) menggabungkan administrasi oral atau topikal psoralen dengan paparan sinar ultraviolet A (UVA). Tepatnya bagaimana bekerja PUVA tidak diketahui. Mekanisme aksi mungkin melibatkan aktivasi dari psoralen oleh sinar UVA yang menghambat produksi abnormal cepat dari sel-sel di kulit psoriasis. Ada beberapa mekanisme aksi yang terkait dengan PUVA, termasuk efek pada sistem kekebalan kulit.

PUVA dikaitkan dengan mual, kelelahan sakit kepala,, terbakar, dan gatal. Pengobatan jangka panjang dikaitkan dengan karsinoma sel skuamosa (tidak dengan melanoma).

Bacaan lebih lanjut

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