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Smple, painless test screens for early-stage colorectal cancer

Published on February 22, 2005 at 7:42 AM · No Comments

Colorectal cancer is currently one of the deadliest forms of cancer -- but also one of the most treatable ... if caught early. There are diagnostic tests on the market today but they typically require extensive patient preparation and invasive procedures -- and often deliver inconclusive results.

IMI International Medical Innovations (IMI), a predictive medicine company, may have the answer. A simple, painless test that can be performed in a doctor's office to screen for early-stage colorectal cancer is in development at IMI with what researchers say are high prospects for success.

"Clearly, an affordable, easy-to-use initial screen for early-stage colorectal cancer is urgently needed," says Dr. Michael Evelegh, head of regulatory and clinical affairs at IMI.

Recent data presented at the American Association for Cancer Research (AACR) showed that IMI's novel test, ColorectAlert(TM), detected more than half of all early-stage cancers and had five times fewer false positives than fecal occult blood tests (FOBTs), currently the leading method of screening. IMI is currently planning a major, multi-site prospective trial that is expected to generate definitive data to support ColorectAlert(TM)'s effectiveness as a screening tool.

ColorectAlert(TM) works by identifying a cancer-associated sugar in a sample of mucus collected by the physician during a routine digital rectal exam. No blood or stool sample is needed. And since the test sample is obtained directly by the physician rather than by the patient, ColorectAlert(TM) should contribute to improved patient compliance.

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