Mayo Clinic researchers report in the September edition of Mayo Clinic Proceedings that bariatric surgery is a safe option for treating obese patients who have coronary artery disease.
The findings are important because coronary artery disease patients can see a significant benefit with a successful procedure. The resulting weight loss is also followed by an improvement in blood pressure, cholesterol, blood sugar and sleep apnea, all factors linked to coronary artery disease.
"In essence, obese patients with coronary artery disease might be those who need this surgery the most, but get it the least," says Francisco Lopez-Jimenez, M.D., Mayo Clinic cardiologist and lead author of the study.
The study is the first report about the safety and efficacy of bariatric surgery in patients with a history of coronary artery disease, the authors say.
"Roux-en-Y bariatric surgery appears to be an important alternative in treating patients with coronary artery disease and obesity who cannot lose weight with standard approaches," says Dr. Lopez-Jimenez. "The surgery appears to be safe in properly evaluated patients with cardiovascular disease."
But Dr. Lopez-Jimenez says additional research is needed to determine the effect of bariatric surgery on cardiovascular events among these patients. The analysis by the Mayo researchers included 52 patients who were identified with coronary artery disease, who underwent bariatric surgery at Mayo Clinic Rochester between March 1995 and January 2002. The effects on body weight and other cardiovascular risk factors were analyzed after surgery. After an average follow-up of 2.5 years with patients, the researchers found significant decreases in weight loss, body mass index and blood pressure. Blood analysis showed decreases in key indicators, as well.