Adamas Pharmaceuticals, Inc., a privately held company, announced today results from in vivo animal studies and in vitro tests demonstrating that its triple combination antiviral drug (TCAD) therapy is superior relative to double combinations and monotherapy against multiple strains of pandemic and avian influenza viruses. Results of these studies were presented Sunday evening in an oral session at the XII International Symposium on Respiratory Viral Infections being held in Taipei.
Currently, virtually all influenza A viruses are resistant to at least one approved antiviral and mounting evidence suggests that monotherapy leads to single and multi-drug resistance, creating a pressing need for new influenza therapies.