Drawing upon over 20 years’ experience - AMSBIO has developed a custom phospho-specific antibody production service** that is both reliable and produces high quality product.
This service** includes synthesis of phosphorylated and non-phosphorylated peptides, conjugation to a carrier protein, immunization, serum production and a 2-step affinity purification of the antibodies. To ensure absolute specificity for each phosphorylated amino acid a stringent dot blot testing regime is carried out guaranteeing that for all projects the phospho peptide is preferentially recognized.
A complete package of non-phosphorylated and phosphorylated peptides, pre-immune sera and antisera as well as affinity purified phospho-specific and non phospho antibodies are supplied with each customer order. The AMSBIO custom phospho-specific antibody production service is cited in the recent research undertaken by F Christian et al*.
For further information on this service please visit www.amsbio.com/Custom-Phospho-Specific-Polyclonal-Antibody-Service.aspx or contact AMSBIO on +44-1235-828200 (Europe / ROW) / +1-800-987-0985 (North America) or email [email protected]. The phospho-specific polyclonal antibody preparation service is part of a suite of custom services from AMSBIO - visit www.amsbio.com/customservices.aspx for further information.
Founded in 1987, AMS Biotechnology (AMSBIO) is recognized today as a leading company contributing to the acceleration of discovery through the provision of cutting-edge life science technology products and services for research and development in the medical, nutrition, cosmetics and energy industries. The AMSBIO range includes specialist antibodies, peptides and recombinant proteins. In addition the company is able to draw upon in-depth expertise in extracellular matrices to provide elegant solutions for studying cell motility, migration, invasion and proliferation. Widely acknowledged as experts in cell culture, AMSBIO partners with clients in tailoring cell systems to enhance screening outcomes and eventual prognosis. With a range of molecular detection reagents, and a significant Biorepository the company can also provide tissue DNA, RNA, protein and microarray products. Key research areas for these products include: Oncology, Regenerative Medicine, Environmental Analysis, Cytotoxicity Screening, Glycomics and Stem Cell Biology.
F. Christian, et al., PKA phosphorylation of p62/SQSTM1 regulates PB1 domain interaction partner binding, Biochim. Biophys. Acta (2014), http://dx.doi.org/10.1016/j.bbamcr.2014.07.021