Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients
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  March 17, 2017  
  Arthritis  
  The latest arthritis news from News Medical  
 Researchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patientsResearchers uncover mechanism that contributes to joint inflammation in rheumatoid arthritis patients
 
New research findings published in the Journal of Leukocyte Biology, suggest that synovial CD4+ T cells that produce IL-21 contribute to joint inflammation by activating synovial fibroblasts in rheumatoid arthritis patients.
 
 
 Study finds higher prevalence of arthritis in recent generationsStudy finds higher prevalence of arthritis in recent generations
 
In an analysis of the Canadian population born between the 1930s and 1960s, each succeeding generation had a higher prevalence of arthritis.
 
   Rheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in miceRheumatoid arthritis drug blocks metabolic pathway, reduces breast cancer tumors in mice
 
Mount Sinai researchers have discovered that a rheumatoid arthritis drug can block a metabolic pathway that occurs in tumors with a common cancer-causing gene mutation, offering a new possible therapy for aggressive cancers with few therapeutic options, according to a study to be published in Cancer Discovery.
 
   High leisure-time physical activity improves cartilage health in postmenopausal women with knee OAHigh leisure-time physical activity improves cartilage health in postmenopausal women with knee OA
 
Higher leisure-time physical activity (LTPA) level promotes cartilage health in postmenopausal women with mild knee osteoarthritis (OA).
 
   Scientists uncover Achilles' heel in unique kind of immune memory cellsScientists uncover Achilles' heel in unique kind of immune memory cells
 
The capacity for memory isn't exclusive to the brain. The immune system, with its sprawling network of diverse cell types, can recall the pathogens it meets, helping it to swiftly neutralize those intruders upon future encounters.
 
 Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse models
 
Scientists use cargo-carrying red blood cells to alleviate autoimmune diseases in mouse modelsUsing red blood cells modified to carry disease-specific antigens, scientists in the laboratories of Hidde Ploegh and Harvey Lodish have prevented and alleviated two autoimmune diseases—multiple sclerosis (MS) and type 1 diabetes—in early stage mouse models.
 
 
 Newly-identified autoimmune endocrine disease is caused by thymomas, study finds
 
Newly-identified autoimmune endocrine disease is caused by thymomas, study findsA Japanese research group has discovered that a newly-identified autoimmune endocrine disease that leads to hypopituitarism is caused by thymomas (a type of tumor originating from the thymic gland).
 
 
 New micro-pump technology may offer promising alternative to eye drops for glaucoma patients
 
New micro-pump technology may offer promising alternative to eye drops for glaucoma patientsIt is no secret that the issues associated with current glaucoma medications can be problematic. Systemic medications carry the risk of side effects, while the current medical treatment of choice, eye drops, has its own drawbacks.
 
 
 Review identifies treatment methods to reduce complications in TKR patients with obesity
 
Review identifies treatment methods to reduce complications in TKR patients with obesityObesity affects 35 percent of the adult population in the U.S. A new literature review published in the Journal of the American Academy of Orthopaedic Surgeons identifies strategies to improve total knee replacement outcomes in patients with obesity.
 
 
 Mayo Clinic researchers discover three new senolytic drugs
 
Mayo Clinic researchers discover three new senolytic drugsMayo Clinic researchers have uncovered three new agents to add to the emerging repertoire of drugs that aim to delay the onset of aging by targeting senescent cells - cells that contribute to frailty and other age-related conditions.
 
 
 Sex differences in microglia activity affect pain treatment, study finds
 
Sex differences in microglia activity affect pain treatment, study findsA female brain's resident immune cells are more active in regions involved in pain processing relative to males, according to a recent study by Georgia State University researchers.
 
 
 Researchers discover new way to develop painkillers without harmful side effects
 
Researchers discover new way to develop painkillers without harmful side effectsResearchers from Charité - Universitätsmedizin Berlin have discovered a new way of developing painkillers.
 
 
 Researchers discover new way to curb chronic pain
 
Researchers discover new way to curb chronic painFor millions of sufferers, there is nothing more debilitating than chronic back or joint pain. It can feel like a lifetime of misery.
 
 
 Shared decision making leads to better patient outcomes, higher satisfaction rates
 
Shared decision making leads to better patient outcomes, higher satisfaction ratesWell-informed patients who decide with their orthopaedic surgeon what treatment is best for them have better outcomes and higher patient satisfaction rates, according to new study presented today at the 2017 Annual Meeting of the American Academy of Orthopaedic Surgeons.
 
 
 Age may not be discernible factor on outcomes of shoulder replacement surgery, study suggests
 
Age may not be discernible factor on outcomes of shoulder replacement surgery, study suggestsWhether you're younger than 65 or older than 75, age may not be a discernible factor in the success of shoulder replacement surgery, according to a Henry Ford Hospital study.
 
 
 Increased uric acid levels in early life may lead to high blood pressure later on
 
Increased uric acid levels in early life may lead to high blood pressure later onA new article published in the American Journal of Hypertension finds that very young children with increased uric acid levels had higher blood pressure at 3 years of age.