Researchers develop new way of visualizing distribution of cholesterol in cells, tissues
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  March 22, 2017  
  Cholesterol  
  The latest cholesterol news from News Medical  
 Researchers develop new way of visualizing distribution of cholesterol in cells, tissuesResearchers develop new way of visualizing distribution of cholesterol in cells, tissues
 
Researchers from UCLA and the University of Western Australia have developed a new way of visualizing the distribution of cholesterol in cells and tissues.
 
 
 New class of cholesterol-lowering drug alongside statins can reduce risk of cardiovascular diseasesNew class of cholesterol-lowering drug alongside statins can reduce risk of cardiovascular diseases
 
A new class of cholesterol-lowering drug has been found to help patients cut their risk of cardiovascular disease, stroke and heart attack.
 
   Study: Patients with elevated cholesterol levels face greater risk for rotator cuff surgery failureStudy: Patients with elevated cholesterol levels face greater risk for rotator cuff surgery failure
 
Patients with higher cholesterol levels face a significantly greater risk for failure of minimally invasive (arthroscopic) rotator cuff surgery, according to a new study to be presented on Friday, March 17, at the 2017 Annual Meeting of the American Academy of Orthopaedic Surgeons.
 
   New approach shows promise to prevent, treat cholesterol gallstone diseaseNew approach shows promise to prevent, treat cholesterol gallstone disease
 
According to current estimates, 20 to 25 million Americans have or will develop gallstones, representing almost 15% of adults. Although only a small percentage of individuals with gallstones develop symptoms, more than 700,000 individuals annually undergo surgical gallbladder removal and many more take medications to manage the condition or undergo stone-dissolving procedures.
 
   Cholesterol-lowering statins linked to increased risk of diabetes in older womenCholesterol-lowering statins linked to increased risk of diabetes in older women
 
Older Australian women taking cholesterol-lowering statins face a significantly increased risk of developing diabetes, according to a University of Queensland study.
 
 New gene-silencing drugs cut cholesterol levels by half in early research
 
New gene-silencing drugs cut cholesterol levels by half in early researchThe first in a new class of gene-silencing drugs, known as inclisiran, has been shown to halve cholesterol levels in patients at risk of cardiovascular disease.
 
 
 Novel synthetic HDL-C injection shows no benefit on arterial plaques
 
Novel synthetic HDL-C injection shows no benefit on arterial plaquesInjection of a novel form of synthetic high-density lipoprotein cholesterol (HDL-C), or good cholesterol, into the arteries of patients who had recently had a heart attack did not reduce the volume of fatty deposits, or plaque, in the arteries, compared with placebo injections, according to research presented at the American College of Cardiology's 66th Annual Scientific Session.
 
 
 Tsimane indigenous South Americans have lowest prevalence of coronary atherosclerosis of any population yet studied
 
Tsimane indigenous South Americans have lowest prevalence of coronary atherosclerosis of any population yet studiedThe Tsimane people – a forager-horticulturalist population of the Bolivian Amazon – have the lowest reported levels of vascular ageing for any population, with coronary atherosclerosis (hardening of the arteries) being five times less common than in the US, according to a study published in The Lancet and being presented at the American College of Cardiology conference.
 
 
 Continuation of statins may improve survival following heart surgery, research shows
 
Continuation of statins may improve survival following heart surgery, research showsPatients on statins should not stop taking the cholesterol-lowering medication before heart surgery—even on the day of surgery, according to an article posted online today in The Annals of Thoracic Surgery.
 
 
 New test measures blood concentrations of plasma ceramides to predict risk for heart attacks, strokes
 
New test measures blood concentrations of plasma ceramides to predict risk for heart attacks, strokesA new type of blood test may help physicians identify which patients with and without evidence of coronary blockages are at risk for heart attacks and strokes.
 
 
 High levels of two biomarkers can predict risk for adverse cardiac events, research suggests
 
High levels of two biomarkers can predict risk for adverse cardiac events, research suggestsNew research suggests that GlycA, a newly identified blood marker, and C-reactive protein both independently predict major adverse cardiac events, including heart failure and death. Patients who have high levels of both biomarkers are at especially high risk.
 
 
 Drosophila models help illuminate molecular mechanisms underlying nephrotic syndrome
 
Drosophila models help illuminate molecular mechanisms underlying nephrotic syndromeThe majority of genes associated with nephrotic syndrome (NS) in humans also play pivotal roles in Drosophila renal function, a conservation of function across species that validates transgenic flies as ideal pre-clinical models to improve understanding of human disease, a Children's National Health System research team reports in a recent issue of Human Molecular Genetics.
 
 
 Online behavioral intervention reduces systolic blood pressure by 10 mmHg, study finds
 
Online behavioral intervention reduces systolic blood pressure by 10 mmHg, study findsIn the first randomized, double-blinded trial of an online behavioral intervention for high blood pressure, participants in web-based lifestyle counseling reduced their systolic blood pressure (the higher number in a blood-pressure reading) by 10 mmHg, compared with a 6 mmHg reduction for those taking part in a web-based control intervention, a statistically significant difference.
 
 
 Severe hypoglycemic episode in people with diabetes may increase risk for heart disease, death
 
Severe hypoglycemic episode in people with diabetes may increase risk for heart disease, deathA single instance of blood sugar falling so low as to require an emergency department visit was associated with nearly double the risk of cardiovascular disease or death, finds a new Johns Hopkins Bloomberg School of Public Health study of older adults with type 2 diabetes.
 
 
 Hormone replacement therapy linked to lower risk of atherosclerosis and death in women
 
Hormone replacement therapy linked to lower risk of atherosclerosis and death in womenHormone replacement therapy has long been controversial as studies have associated it with health benefits and risks. While some studies suggest that it lowers the risk of osteoporosis and improves some aspects of heart health, others link it to higher risk of cancer and stroke.
 
 
 Research shows pNaKtide can attenuate development of NAFLD and atherosclerosis
 
Research shows pNaKtide can attenuate development of NAFLD and atherosclerosisBuilding on their recent research focusing on a peptide, pNaKtide, designed to block the oxidant amplifying function of the cellular sodium-potassium pump, researchers at Marshall University Joan C. Edwards School of Medicine have successfully demonstrated that pNaKtide, can attenuate the development of experimental nonalcoholic fatty liver disease (NAFLD) and atherosclerosis.