Opportunities and risks of direct-to-consumer genetic health risk tests
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  April 19, 2017  
  Genetics  
  The latest Genetics news from News Medical  
 Opportunities and risks of direct-to-consumer genetic health risk testsOpportunities and risks of direct-to-consumer genetic health risk tests
 
Accurate genetic testing stands to transform modern medicine by offering effective, personalized treatment.
 
 
 Researchers correct Duchenne muscular dystrophy using gene-editing alternativeResearchers correct Duchenne muscular dystrophy using gene-editing alternative
 
Using the new gene-editing enzyme CRISPR-Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the lab.
 
   Researchers identify three novel genetic mutations linked to Fuchs dystrophyResearchers identify three novel genetic mutations linked to Fuchs dystrophy
 
Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation.
 
   Human Vaccines Project, VUMC and Illumina team up to decipher genetic underpinnings of immune systemHuman Vaccines Project, VUMC and Illumina team up to decipher genetic underpinnings of immune system
 
The Human Vaccines Project and Vanderbilt University Medical Center (VUMC) today announced that they joined forces with Illumina, Inc., to decipher the human immunome, the genetic underpinnings of the immune system.
 
   'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders'Human knockouts': Genetics in families reveals basic biology and possible therapeutics for disorders
 
More than 1,800 individuals carrying loss-of-function mutations in both copies of their genes, so-called "human knockouts," are described in the first major study to be published in Nature this week by an international collaboration led by the Perelman School of Medicine at the University of Pennsylvania and colleagues.
 
 What is Choroideremia?
 
What is Choroideremia?Choroideremia (CHM) is a rare genetic eye disease that affects the retina, which is the area at the back of the eye that processes all we see into signals that are sent to the brain via the optic nerve.
 
 
 New online genetic study aims to enroll 50,000 individuals and families affected by autism
 
New online genetic study aims to enroll 50,000 individuals and families affected by autismAutism has a strong genetic component. To date, approximately 50 genes have been identified that almost certainly play a role in autism, and researchers estimate that at least an additional 300 are involved.
 
 
 Scientists identify gene responsible for generating key lipid in skin barrier formation
 
Scientists identify gene responsible for generating key lipid in skin barrier formationScientists have identified the gene responsible for generating acylceramide, the key lipid in forming the skin barrier that protects us from pathogens, allergens and other harmful substances. This finding could prove crucial in developing medicines for treating atopic dermatitis and ichthyosis.
 
 
 Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeutics
 
Vanderbilt geneticists find new way to tap plant pharmacopeia to produce improved therapeuticsCocaine, nicotine, capsaicin. These are just three familiar examples of the hundreds of thousands of small molecules (also called specialized or secondary metabolites) that plants use as chemical ammunition to protect themselves from predation.
 
 
 Researchers uncover global regulator that 'switches on' silent biosynthetic gene clusters
 
Researchers uncover global regulator that 'switches on' silent biosynthetic gene clustersBacteria have supplied some of today's most indispensable anti-cancer and anti-bacterial drugs. Yet these compounds comprise only a fraction of their possible offerings. Now, researchers have found a way to unleash their full potential as natural product dispensers.
 
 
 Microparticles show potential to deliver DNA-based vaccines and gene therapies in pill form
 
Microparticles show potential to deliver DNA-based vaccines and gene therapies in pill formA microscopic corn-and-shrimp cocktail could eventually make DNA-based vaccinations and cancer-treating gene therapies an easier pill to swallow, according to new research from the University of Nebraska-Lincoln.
 
 
 New blood test can accurately, quickly identify genetic mutations linked to NSCLC
 
New blood test can accurately, quickly identify genetic mutations linked to NSCLCIdentification of a specific genetic mutation in patients with non-small-cell lung cancer (NSCLC) helps clinicians select the best treatment option. Potential NSCLC patients usually undergo invasive tissue biopsy, which may often be unnecessary and delays treatment.
 
 
 New study shows big differences in tissue gene expression between male and female pigeons
 
New study shows big differences in tissue gene expression between male and female pigeonsIn experimental research, scientists tend to assume that -- unless they are looking specifically at reproduction or sexual behavior -- male and female animals are alike, and mostly use males.
 
 
 New 7-gene test strategy could improve life expectancy for women at risk of hereditary breast cancer
 
New 7-gene test strategy could improve life expectancy for women at risk of hereditary breast cancerValue in Health, the official journal of the International Society for Pharmacoeconomics and Outcomes Research, announced today the publication of new research indicating that testing for variants in 7 cancer-associated genes (versus the usual process of testing in just 2 genes) followed by risk-reduction management could cost-effectively improve life expectancy for women at risk of hereditary breast cancer.
 
 
 Scientists discover potential trigger for MDS in children with rare genetic disorder
 
Scientists discover potential trigger for MDS in children with rare genetic disorderMyelodysplastic syndrome is an umbrella term used to describe disorders characterized by the bone marrow's inability to produce normal blood cells.
 
 
 UVA researcher develops new way to track genes inside living cells
 
UVA researcher develops new way to track genes inside living cellsFor Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.
 
 
 Seeing genes inside living cells
 
Seeing genes inside living cellsFor Mazhar Adli, the little glowing dots dancing about on the computer screen are nothing less than the fulfillment of a dream. Those fluorescent dots, moving in real time, are set to illuminate our understanding of the human genome, cancer and other genetic diseases in a way never before possible.
 
 
 International research effort reveals major insights into spread of West African Ebola epidemic
 
International research effort reveals major insights into spread of West African Ebola epidemicAn international effort to analyze the entire database of Ebola virus genomes from the 2013-2016 West African epidemic reveals insights into factors that sped or slowed the rampage and calls for using real-time sequencing and data-sharing to contain future viral disease outbreaks.
 
 
 Targeted treatment slows progression of two degenerative brain diseases in mice
 
Targeted treatment slows progression of two degenerative brain diseases in miceScientists report a significant step toward combatting two degenerative brain diseases that chip away at an individual's ability to move, and think.
 
 
 LIH scientists discover unknown immune activation mechanism to ward off pathogens
 
LIH scientists discover unknown immune activation mechanism to ward off pathogensScientists of the Luxembourg Institute of Health have discovered a so far unknown molecular mechanism by which the human immune system activates its immune cells: T cells, a particular type of white blood cells, effectively ward off pathogens if a gene known as Gclc is expressed within them.
 
 
 Researchers reveal immune machinery that goes awry to trigger neutrophilic dermatosis
 
Researchers reveal immune machinery that goes awry to trigger neutrophilic dermatosisA research team led by St. Jude Children's Research Hospital immunologists has revealed a previously unknown immune machinery that goes awry to trigger the inflammatory disease neutrophilic dermatosis.
 
 
 Nanoparticle-programmed immune cells can slow progression of leukemia in mouse model
 
Nanoparticle-programmed immune cells can slow progression of leukemia in mouse modelResearchers at Fred Hutchinson Cancer Research Center have developed biodegradable nanoparticles that can be used to genetically program immune cells to recognize and destroy cancer cells -- while the immune cells are still inside the body.
 
 
 Developmental Split-Brain syndrome discovery
 
Developmental Split-Brain syndrome discoveryOur group describes a new entity, which we refer to as “Developmental Split-Brain syndrome” which we discovered affected four individuals from three unrelated families. All affected individuals showed disruption of communicating tracts between the right and left side of the brain which meant that there is lack of coordination and communication between the two sides of the brain.
 
 
 NIH study provides unprecedented detail on host response to Ebola virus disease
 
NIH study provides unprecedented detail on host response to Ebola virus diseaseAnalysis of daily gene activation in a patient with severe Ebola virus disease cared for at the National Institutes of Health (NIH) in 2015 found changes in antiviral and immune response genes that pinpointed key transition points in the response to infection.
 
 
 Researchers use CRISPR technology to create new strain of red-eyed mutant wasps
 
Researchers use CRISPR technology to create new strain of red-eyed mutant waspsResearchers at UC Riverside's Akbari lab have brought a new strain of red-eyed mutant wasps into the world.
 
 
 Scientists discover how insulin-producing cells show differences in age
 
Scientists discover how insulin-producing cells show differences in ageDiabetes researchers have puzzled for decades about why insulin-producing beta cells in one pancreatic islet often look and behave quite differently than their counterparts in the same islet or in nearby islets.