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Search results for 'cleft lip'


Genes more important in cleft lip and palate than previously thought Comparing 500,000 snippets of human DNA put scientists from the University of Bonn on the right track. http://www.news-medical.net/news/2009/03/08/46618.aspx
Why do teeth form in a single row? A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published in the journal Science. http://www.news-medical.net/news/2009/02/26/46314.aspx
Domain duplication, divergence, and loss events in vertebrate Msx paralogs reveal phylogenomically informed disease markers The work of Forsyth scientist Peter Jezewski, DDS, Ph.D., has revealed that duplication and diversification of protein regions ('modules') within ancient master control genes is key to the understanding of certain birth disorders. http://www.news-medical.net/news/2009/01/15/45014.aspx
Smoking during the first trimester of pregnancy linked to oral clefts Smoking during the first trimester of pregnancy is clearly linked with an increased risk of cleft lip in newborns. http://www.news-medical.net/news/2008/12/18/44416.aspx
Discovery of new gene responsible for puberty disorders A new gene responsible for some puberty disorders has been identified by Medical College of Georgia researchers. http://www.news-medical.net/news/2008/10/27/42199.aspx
Discovery of gene variant for cleft lip About 20 percent of isolated cleft lip, one of the world's most common birth defects, may be due to a one-letter difference in the DNA sequence of a gene involved in facial development, researchers supported by the National Institutes of Health report. http://www.news-medical.net/news/2008/10/06/41851.aspx
Binge drinking in pregnancy increases risk of oral clefts in offspring A new study by researchers at the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health, shows that pregnant women who binge drink early in their pregnancy increase the likelihood that their babies will be born with oral clefts. http://www.news-medical.net/news/2008/07/31/40412.aspx
Palatal surgery in less lexically advanced, younger children associated with better speech outcomes A new study published in The Cleft Palate-Craniofacial Journal has found that the timing of palatal surgery and size of lexicon, or vocabulary, in children are important factors to consider in determining the most beneficial management of children with cleft palate. http://www.news-medical.net/news/2008/05/15/38366.aspx
New surgical device earns high marks from combat surgeons Results of an independent clinical study conducted by U.S. Army combat support surgeons in Baghdad show that a new medical device used to close a type of surgical wound more quickly is saving lives and limbs of soldiers and civilians. http://www.news-medical.net/news/2008/05/02/38010.aspx
Discovery of gene behind clefting disorder Branchio-Oculo-Facial syndrome In a collaborative effort, researchers from Boston University School of Medicine (BUSM) have discovered that deletions or mutations within the TFAP2A gene (Activating Enhancer-Binding Protein) result in the distinctive clefting disorder Branchio-Oculo-Facial syndrome (BOFS). http://www.news-medical.net/news/2008/04/23/37698.aspx
Cellcept immunosuppressant further linked to birth defects A new study documents malformations seen in an infant born to a kidney transplant recipient who had taken mycophenolate mofetil (MMF), a widely used immunosuppressant available commercially as Cellcept. http://www.news-medical.net/news/2008/02/07/35013.aspx
Educating local physicians key to care of children with cleft deformities in Zimbabwe A surgical team that traveled to Zimbabwe successfully treated 39 children with cleft lip or palate, and an ongoing relationship with physicians there will help meet the needs of local patients, according to an article that will appear in the November/December 2007 print issue of Archives of Facial Plastic Surgery, one of the JAMA/Archives journals. http://www.news-medical.net/news/2007/10/22/31538.aspx
Folic acid helps prevent facial cleft A new study finds that women who take folic acid supplements early in their pregnancy can substantially reduce their baby's chances of being born with a facial cleft. http://www.news-medical.net/news/2007/09/05/29512.aspx
Folic acid appears to reduce risk of cleft lip and palate A new study finds that women who take folic acid supplements early in their pregnancy can substantially reduce their baby's chances of being born with a facial cleft. http://www.news-medical.net/news/2007/01/28/21503.aspx
SUMO1 gene implicated in cleft lip and palate defects Researchers supported by the National Institutes of Health report in the current issue of the journal Science that a much-studied gene called SUMO1, when under expressed, can cause cleft lip and palate, one of the world's most common birth defects. http://www.news-medical.net/news/2006/09/21/20283.aspx
National estimates for 18 specific major birth defects between 1999 and 2001 Cleft lip is a treatable birth defect, but for the families of the estimated 6,800 U.S. infants born with one, it's a heartbreaking experience – not only because of the associated health problems, but because friends and family may ignore the condition or because of social stigma associated with facial defects. http://www.news-medical.net/news/2006/01/05/15188.aspx
New genetic test can predict cleft lip or palate Researchers have developed a new genetic test that can help predict whether parents who have one child with the "isolated" form of cleft lip or palate are likely to have a second child with the same birth defect. Isolated clefts account for 70 percent of all cleft lip and palate cases. http://www.news-medical.net/news/2004/09/10/4701.aspx
Research sheds shed light on a common cause of miscarriage in humans Top poker players know that the face mirrors the brain. Specialists in embryonic development wouldn’t disagree. In fact, because the same clumps of primordial cells mold the final features of both, a close look at a child’s face can often yield clues about less visible problems within the skull http://www.news-medical.net/news/2004/08/20/4217.aspx
Gene variant that is a major contributor to cleft lip An international team of researchers has identified a gene variant that is a major contributor to oral clefts and triples the risk of recurrence in affected families, it was reported today in The New England Journal of Medicine. http://www.news-medical.net/news/2004/08/18/4179.aspx
Scientists have discovered a genetic cause of cleft lip and palate in mice By watching mice “dance” and comparing the DNA of the dancers to their flat-footed siblings, scientists have discovered a genetic cause of cleft lip and palate in mice, a finding that is already being used to search for a similar genetic defect in humans. http://www.news-medical.net/news/2004/04/29/1061.aspx
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