Alzheimer's Disease News and Research

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Alzheimer's disease (AD) is an irreversible, progressive brain disease that slowly destroys memory and thinking skills and, eventually, the ability to carry out the simplest tasks of daily living. In most people with AD, symptoms first appear after age 60. AD is the most common cause of dementia among older people, but it is not a normal part of aging. Dementia refers to a decline in cognitive function that interferes with daily life and activities. AD starts in a region of the brain that affects recent memory, then gradually spreads to other parts of the brain. Although treatment can slow the progression of AD and help manage its symptoms in some people, currently there is no cure for this devastating disease.

$9 billion cost of depression in senior citizens

A new study reveals that depression among senior citizens carries a huge unrecognized cost: many extra hours of unpaid help with everyday activities, delivered by the depressed seniors’ spouses, adult children and friends.

1 May 2004

Counseling eases the depression of people caring for a loved one with the devastating brain disease

The spouses of Alzheimer's patients often experience extraordinary psychological stress, but a new study by NYU School of Medicine researchers shows that a six-session counseling and long-term support program substantially eases the depression of people caring for a loved one with the devastating brain disease, and that the mental health benefits apparently are long lasting.

1 May 2004

First imaging-based diagnostic test for living Alzheimer’s

Mayo Clinic researchers have devised a way to produce enhanced MRI (magnetic resonance imaging) pictures of the destructive brain lesions that cause Alzheimer’s disease. This advance using laboratory mice lays the foundation for the first imaging-based diagnostic test for living Alzheimer’s disease patients.

30 Apr 2004

Gene therapy may delay Alzheimer progression

Results from a preliminary eight-patient study of gene therapy for Alzheimer’s disease are positive enough to justify a larger clinical trial, Mark H. Tuszynski, M.D., Ph.D., reported April 27 at the 56th Annual Meeting of the American Academy of Neurology. Dr. Tuszynski says that a larger trial is being planned at a major medical center in Chicago.

30 Apr 2004

Stroke survivors have twice the risk of dementia compared to stroke-free men and women of the same age

The risk of dementia increases dramatically with advancing age. Our results show that sustaining a stroke increases this risk even further,” said lead author Cristina S. Ivan, M.D. a fellow in stroke and cerebrovascular disorders at the Boston Medical Center. “Dementia is a growing problem because of the aging of the population, particularly the ‘baby boomers’.

29 Apr 2004

A burst of brain energy depends more on a unique molecular cycle than on blood flow variation

A century old mystery is taking place in your head as you read these words. Blood vessels in regions of your brain are widening, bathing cells in an increased blood flow.

28 Apr 2004

Greater severity of depressive symptoms correlates with increased risk of stroke among whites

Greater severity of depressive symptoms correlates with increased risk of stroke among whites, according to research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

28 Apr 2004

PET imaging has recently been shown to aid in the diagnosis of particular neurological syndromes associated with cancer

PET imaging has been shown to improve detection of a variety of cancers, and earlier tests have suggested this technique may be useful in identifying small tumors in patients with paraneoplastic neurological disorders. But PET imaging is not yet widely available, and clear indicators of clinically meaningful outcomes using PET are essential to warrant use with this patient population.

28 Apr 2004

A popular supplement, coenzyme Q10 (CoQ10), may help prevent migraine

Migraine patients who took 100 mg three times a day of CoQ10—which acts as the body’s energy producer—had fewer attacks in three months than those who took a placebo. The participants taking CoQ10 also had fewer days with a headache and fewer days with nausea.

28 Apr 2004

McMaster’s is helping raise awareness of the importance of regular blood pressure monitoring.

A recently launched "Community Hypertension Awareness Program" (CHAP) is 'closing the loop' between health promotion activities in the community, and clinical care by family doctors.

28 Apr 2004

Results look promising in Alzheimer’s gene therapy trial

Surgical placement of genetically modified tissue directly into the brains of patients with Alzheimer’s disease, an experimental approach to delaying brain cell loss associated with the disease, leads to increased metabolic activity in the brain, with cells apparently responding to the insertion of growth factor-producing grafts

28 Apr 2004

Prana Biotechnology gets US$20 million funding for Alzheimer’s treatment research

Prana Biotechnology Limited has announced that it entered into definitive agreements with new institutional investors for the purchase of US$20 million of securities through the sale of 4 million ADR's at US$5.00 per ADR.

28 Apr 2004

Blood pressure drug helps delay ischemic brain damage in stroke patients

A drug used to lower blood pressure can help stop or delay the progress of further ischemic brain lesions in stroke patients according to research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease

One variant of the apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease, according to an analysis of research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Improvement of Parkinson’s disease symptoms when neurorestorative molecule pumped to the center of the brain

A recent study has shown clinical improvement of Parkinson’s disease symptoms after long-term infusion of a neurorestorative molecule, pumped directly to the center of the brain. The study will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Researchers show that language “center” of brain shifts with age

Along with left- or right-handedness, the hemisphere of the brain where language capacity resides is likely predetermined. Researchers have now shown that with age, language capacity in the brain becomes more evenly distributed between hemispheres.

27 Apr 2004

The muscle supplement creatine is safe, but not effective, in pediatric neuromuscular disease

The muscle supplement creatine can be safely taken by children with neuromuscular diseases, but does not improve strength or muscle mass, according to research that will be presented at the American Academy of Neurology 56th Annual Meeting in San Francisco, Calif., April 24 – May 1, 2004.

27 Apr 2004

Women who have migraines with aura have a more than 50 percent increased risk of total stroke and 70 percent increase of ischemic stroke

Women who have migraines with aura have a more than 50 percent increased risk of total stroke and 70 percent increase of ischemic stroke compared to those without migraines, according to research that will be presented at the American Academy of Neurology 56th Annual Meeting

27 Apr 2004

Landscape architects brighten life of elderly patients with schizophrenia and Alzheimer’s disease

Landscape architects at Manchester Metropolitan University have designed a special garden for elderly patients with schizophrenia and Alzheimer’s disease.

27 Apr 2004

Parkinson’s disease drug Pergolide effective in treating restless legs syndrome

Pergolide, a drug commonly used to treat Parkinson’s disease symptoms, has recently been shown to be effective in treating restless legs syndrome. Researchers from seven countries collaborated on the study, published in the April 27 issue of Neurology, the scientific journal of the American Academy of Neurology.

26 Apr 2004

Alzheimer's Disease News and Research

Further Reading

$9 billion cost of depression in senior citizens

Counseling eases the depression of people caring for a loved one with the devastating brain disease

First imaging-based diagnostic test for living Alzheimer’s

Gene therapy may delay Alzheimer progression

Stroke survivors have twice the risk of dementia compared to stroke-free men and women of the same age

A burst of brain energy depends more on a unique molecular cycle than on blood flow variation

Greater severity of depressive symptoms correlates with increased risk of stroke among whites

PET imaging has recently been shown to aid in the diagnosis of particular neurological syndromes associated with cancer

A popular supplement, coenzyme Q10 (CoQ10), may help prevent migraine

McMaster’s is helping raise awareness of the importance of regular blood pressure monitoring.

Results look promising in Alzheimer’s gene therapy trial

Prana Biotechnology gets US$20 million funding for Alzheimer’s treatment research

Blood pressure drug helps delay ischemic brain damage in stroke patients

Apolipoprotein E (APOE) gene may increase the risk of Parkinson’s disease

Improvement of Parkinson’s disease symptoms when neurorestorative molecule pumped to the center of the brain

Researchers show that language “center” of brain shifts with age

The muscle supplement creatine is safe, but not effective, in pediatric neuromuscular disease

Women who have migraines with aura have a more than 50 percent increased risk of total stroke and 70 percent increase of ischemic stroke

Landscape architects brighten life of elderly patients with schizophrenia and Alzheimer’s disease

Parkinson’s disease drug Pergolide effective in treating restless legs syndrome

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