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New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Silibinin: An old molecule with new promise in cancer treatment

A new review paper was published in Oncotarget's Volume 15 on May 23, 2024, entitled, "The importance of integrated therapies on cancer: Silibinin, an old and new molecule."

28 May 2024

Light therapy may affect healing in the brains of people who suffered traumatic brain injury

Low-level light therapy appears to affect healing in the brains of people who suffered significant brain injuries, according to a study published today in Radiology, a journal of the Radiological Society of North America.

28 May 2024

Exonate appoints Dr Rafiq Hasan as Non-Executive Director

Exonate Ltd., a biotechnology company developing novel, non-invasive, small-molecule therapeutics for patients with retinal vascular diseases, today announced the expansion of its Board with the appointment of Dr Rafiq Hasan as Non-Executive Director. Rafiq brings extensive expertise in ophthalmology, specifically within the diabetic eye disease sector, from his years in global pharmaceutical businesses.

28 May 2024

Advanced techniques reveal plectasin's velcro-like action against bacteria

A small antibiotic called plectasin uses an innovative mechanism to kill bacteria. By assembling into large structures, plectasin latches onto its target on the bacterial cell surface comparable to how both sides of Velcro form a bond.

25 May 2024

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

The treatment landscape for multiple myeloma, the second most common blood cancer, is shifting rapidly, with newly diagnosed patients increasingly being treated with a four-part drug combination that includes a new immunotherapy agent.

24 May 2024

New small molecule offers hope in combating antibiotic resistance

Researchers from the University of Oxford have developed a new small molecule that can suppress the evolution of antibiotic resistance in bacteria and make resistant bacteria more susceptible to antibiotics.

24 May 2024

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Non-hormonal sperm-specific approach offers a promising option for reversible male contraception

The world's population has increased by more than 2.6-fold in the last 60 years. The growing trend continues – projections indicate that the number of people living on our planet will grow to 9 billion by 2037 from 8 billion in 2022.

23 May 2024

Insilico Medicine's leadership to address key challenges in AI drug discovery at BIO Convention

Leadership from clinical stage artificial intelligence (AI)-powered drug discovery company Insilico Medicine ("Insilico") will attend the BIO International Convention in San Diego June 3-6 and present on key issues facing AI drug discovery.

23 May 2024

AI algorithm maps protein clumping characteristics in neurodegenerative disorders

The clumping of proteins is at the root of a wide range of neurodegenerative disorders that affect the brain such as Alzheimer's and dementia.

23 May 2024

PhoreMost introduces GlueSEEKER platform for discovery of molecular glue degraders

PhoreMost Ltd., a leading UK biopharmaceutical company unlocking the next generation of drug targets, today announced the introduction of GlueSEEKER™.

From PhoreMost 22 May 2024

New drug-like molecules show promise in preventing influenza by blocking virus entry

Currently available flu medications only target the virus after it has already established an infection, but what if a drug could prevent infection in the first place?

21 May 2024

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy and Johns Hopkins Drug Discovery.

21 May 2024

Researchers decipher how immune cells spot cancer's turbocharged metabolism

When cells become tumor cells, their metabolism changes fundamentally. Researchers at the University of Basel and the University Hospital Basel have now demonstrated that this change leaves traces that could provide targets for cancer immunotherapies.

21 May 2024

Molecule News and Research

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

Silibinin: An old molecule with new promise in cancer treatment

Light therapy may affect healing in the brains of people who suffered traumatic brain injury

Exonate appoints Dr Rafiq Hasan as Non-Executive Director

Advanced techniques reveal plectasin's velcro-like action against bacteria

Evolving treatment paradigms in multiple myeloma could improve patient outcomes

New small molecule offers hope in combating antibiotic resistance

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Non-hormonal sperm-specific approach offers a promising option for reversible male contraception

Insilico Medicine's leadership to address key challenges in AI drug discovery at BIO Convention

AI algorithm maps protein clumping characteristics in neurodegenerative disorders

PhoreMost introduces GlueSEEKER platform for discovery of molecular glue degraders

New drug-like molecules show promise in preventing influenza by blocking virus entry

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

Researchers decipher how immune cells spot cancer's turbocharged metabolism

Study offers new insights into how ketamine works

Scientists uncover protein folding secrets through sound

Groundbreaking study advances human in vitro gametogenesis for infertility treatment

Study uncovers key biological pathways driving psoriasis inflammation

Disabling survival pathways could be a promising strategy for brain tumor treatment

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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