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Exploring immunogenicity, boosting efficacy and safety of modified vaccinia Ankara-Bavarian Nordic vaccine

Researchers evaluated the immunogenicity, boosting efficacy, and safety of single-dose and two-dose MVA-BN (modified vaccinia Ankara-Bavarian Nordic) vaccinations in comparison to replicating smallpox vaccines.

7 Dec 2022

Innovative precision oncology enabled by micro-organospheres derived from patients

The development of an automatic microfluidics droplet platform to rapidly generate patient-derived models of cancer.

6 Dec 2022

UCSC engineers develop new method to automate the growth of cerebral organoids

A team of engineers at UC Santa Cruz has developed a new method for remote automation of the growth of cerebral organoids – miniature, three-dimensional models of brain tissue grown from stem cells.

28 Nov 2022

Can SARS-CoV-2 be inactivated by resonance caused by sound waves at the ultrasound frequency?

Researchers performed in vitro experiments to test the ability of different frequencies of ultrasound to inactivate SARS-CoV-2.

23 Nov 2022

The stability of SARS-CoV-2 variants in aerosols and on high density polyethylene

Researchers showed that some SARS-CoV-2 variants of concern exhibit greater surface and aerosol stability than the ancestral strain.

23 Nov 2022

WHO‒recommended alcohol-based hand rub formulations show efficacy against Monkeypox virus

Researchers demonstrated the efficacy of two World Health Organization (WHO)‒recommended alcohol-based hand rub solutions to inactivate the monkeypox virus (MPXV).

21 Nov 2022

Frozen and viable: successful culture of replicating SARS-CoV-2 from hospital aerosol samples after freezing

Researchers demonstrated the presence of infectious SARS-CoV-2 in samples from the hospital rooms of SARS-CoV-2-infected patients.

21 Nov 2022

Research could lead to better postoperative care for patients who need shoulder arthroplasty revisions

The most common bacterial infection to occur after revision shoulder arthroplasty surgery can be diagnosed more accurately by considering how quickly samples of the microbe grow in hospital labs and the level of bacteria that grows, a study partly performed at UT Southwestern shows.

31 Oct 2022

Vaccination- and/or natural infection-induced immune responses against SARS-CoV-2 Omicron subvariants

Researchers comparatively evaluated the neutralization antibody titers for SARS-CoV-2 Omicron VOC subvariants BA.1, BA.2, BA.4/5 among individuals with ancestral B.1 strain infections, vaccinated individuals, or with hybrid immunity from breakthrough infections and vaccinations with Delta or Gamma VOCs.

27 Oct 2022

Scientists develop human salivary gland organoids to test SARS-CoV-2 infectivity

In a recent study published in the journal Nature Cell Biology, researchers demonstrated the susceptibility of salivary glands to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in vitro using an organoid culture model.

20 Oct 2022

Are pediatric COVID-19 samples less infectious?

Researchers determine whether children are less hospitable to SARS-CoV-2 and, as a result, pose a lower risk of a viral spread than adults.

20 Oct 2022

Study presents rare cases of COVID-19-associated pulmonary aspergillosis

Researchers presented a case series of patients with coronavirus disease 2019 (COVID-19)-associated pulmonary aspergillosis (CAPA). The goal of the study was to inform clinicians and healthcare workers of this serious COVID-19-related complication.

14 Oct 2022

The impact of humidity levels on viral transmission and viability

A recent PLoS ONE study reviewed the impact of humidity on virus transmission and its viability.

13 Oct 2022

The ability of antiviral formulation ViruSAL to inhibit SARS-CoV-2 infectivity

Researchers from Ireland used human bronchial epithelium models to evaluate the ability of a novel proprietary formulation called ViruSAL to inhibit SARS-CoV-2 infections.

12 Oct 2022

The efficacy of UR GUV devices against aerosolized SARS-CoV-2

Researchers assessed the real-time inactivation of SARS-CoV-2 using ultraviolet-C.

12 Oct 2022

How do clinical outcomes in patients infected with different Omicron subvariants differ?

Researchers compare the clinical outcomes, upper respiratory viral loads, and viral recovery of different SARS-CoV-2 Omicron subvariants on cell cultures.

27 Sep 2022

Study reveals pan-antiviral properties of PDC-109 bovine seminal plasma protein

In a new study, researchers explored the antiviral activity of the bovine seminal plasma protein PDC-109 against various mammalian viruses, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

15 Sep 2022

What is the impact of COVID-19 treatments targeting intracellular Neu1?

In a new study, researchers assessed the impact of targeting intracellular Neu1 on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

14 Sep 2022

Parenteral-prime mucosal boost an effective strategy to protect against SARS-CoV-2

In a recent study published in the journal eBioMedicine, researchers in Denmark and Sweden administered a cationic liposome-adjuvanted severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein subunit vaccine as a subcutaneous (s.c.) prime-intranasal (i.n.) boost strategy to elicit mucosal immune responses among SARS-CoV-2-infected Syrian hamsters.