Liquid Chromatography News and Research

RSS

Wide variability in rheumatoid arthritis drug Methotrexate suggests alternative dosing should be considered

Methotrexate (MTX) is commonly used to treat rheumatoid arthritis (RA) and is suggested as the "anchor" drug in treating the disease.

5 Nov 2008

Near-infrared nanoparticles shine a bright light on cancer

A new nanoparticle-enabled imaging method for breast cancer has been developed by a team of scientists from Penn State. Their research, utilizing encapsulated fluorescent molecules in calcium phosphate nanoparticles and nontoxic near infrared (NIR) imaging, appears in the journal ACS Nano.

27 Oct 2008

Discovery of earliest known cases of human tuberculosis in Neolithic village

The discovery of the earliest known cases of human tuberculosis (TB) in bones found submerged off the coast of Israel shows that the disease is 3000 years older than previously thought. Direct examination of this ancient DNA confirms the latest theory that bovine TB evolved later than human TB.

14 Oct 2008

Existing anti-obesity drugs may be effective against flu, hepatitis and HIV

Viruses dramatically increase cellular metabolism, and existing anti-obesity drugs may represent a new way to block these metabolic changes and inhibit viral infection, according to a study published today in the journal Nature Biotechnology.

29 Sep 2008

New method to detect fake Tamiflu

Chemists in Georgia are reporting development of a fast new method to detect fake Tamiflu, the mainstay medication for preventing and treating bird flu.

8 Apr 2008

Scorpion venom may hold key to controlling cystic fibrosis

Researchers have discovered a peptide in scorpion venom that may hold the key to understanding and controlling cystic fibrosis and other secretory diseases.

17 Feb 2008

New method to identify genetic determinants of Alzheimer's

A rapid and accurate DHPLC assay for determination of apolipoprotein E genotypes has been developed by researchers from the Department of Medical Genetics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, China.

14 Jan 2008

How can some people live at high altitudes and thrive while others struggle?

The answer for Tibetans who live at altitudes around 14,000 feet is increased nitric oxide (NO) levels. High levels of NO circulate in various forms in the blood and produce the physiological mechanisms that cause the increased blood flow that maintains oxygen delivery despite hypoxia - low levels of oxygen in the ambient air and the bloodstream.

31 Oct 2007

Purer medicines

Dutch researcher Roelof Mol has investigated possibilities for more accurately determining the composition of medicines.

24 Oct 2007

Alternative methods proposed to detect pesticides and antibiotics in water and natural food

Water or food of natural origins (from plants or animals) that we consume on a daily basis can contain unwanted ‘supplies' for our organism, such as pesticides or antibiotics.

18 Sep 2007

New findings on vitamin D

Surprising findings by Queen's University researchers have shed new light on how the 'sunshine vitamin' - D - increasingly used to treat and prevent cancer and other diseases is broken down by our bodies.

25 Jul 2007

New human medications found in fish in Texas

Baylor University researchers have found the residue of three new human medications in fish living in the Pecan Creek in North Texas.

2 May 2007

Resveratrol and red wine

Red wine is being widely touted for its health benefits, but not all red wines may act the same according to researchers at the University of Hertfordshire.

24 Apr 2007

New microfluidic device suitable for large-scale screening of disease-related biomarkers

Researchers at the Virginia Bioinformatics Institute (VBI) at Virginia Tech have developed a disposable microchip that replaces space-consuming instrumentation with fast, cost-effective, lab-on-a-chip technology.

5 Sep 2006

Structural alterations in breast stromal and epithelial DNA

Researchers have uncovered a pattern of DNA damage in connective tissues in the human breast that could shed light on the early stages of breast cancer.

3 Aug 2006

Mushrooms are a great source of antioxidants

Using a new, more sensitive-testing approach they developed for fungi, Penn State food scientists have found that mushrooms are a better natural source of the antioxidant ergothioneine than either of the two dietary sources previously believed to be best

31 Aug 2005

Excessive alcohol consumption increases risk of certain cancers

Researchers at the National Institute of Standards and Technology (NIST) have developed a new chemical analysis method that has assisted researchers at the National Institute of Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health, in demonstrating a potentially important chemical link between alcohol consumption and cancer.

11 Aug 2005