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Cryo-EM study elucidates 3D structure and molecular mechanism of platelet drug transporter

A research team led by Prof. CHEN Yuxing and Prof. ZHOU Cong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) recently utilized single-particle cryogenic electron microscopy (cryo-EM) to decipher the 3D structure and molecular mechanism of the platelet drug transporter ABCC4.

28 Jul 2023

The role of vasomotor reactivity in COVID-19 patients

Researchers searched and collated the most relevant published literature on cerebral hemodynamic changes in COVID-19 patients.

27 Jul 2023

Could Machine Learning models serve to predict depression in early pregnancy in racial/ethnic minority women?

Researchers built and assessed machine learning models to predict depression in pregnant women using electronic medical record data.

20 Jul 2023

COVID-19 severity linked to autoantibodies against blood clotting protein

Study investigates the occurrence of ADAMTS13 antibodies in COVID-19 patients and their association with disease severity and lower ADAMTS13 activity. The findings suggest the need to include ADAMTS13 antibodies in diagnosing and managing SARS-CoV-2 infections.

2 Jul 2023

Do Panax notoginseng saponins (Xuesaitong soft capsules) improve function in patients with ischemic stroke?

Researchers examined the effectiveness and safety of using Panax notoginseng saponins for ischemic stroke in adults.

22 Jun 2023

Study reveals that wine consumption has an inverse relationship to cardiovascular mortality

Researchers aimed to understand the association between wine consumption and cardiovascular health.

20 Jun 2023

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

Humanigen, Inc.today extended previously reported results by presenting additional, statistically significant hematologic improvements and reductions in inflammatory markers from lenzilumab, its investigational drug, in a Phase 2/3 trial of treatment-naïve participants with chronic myelomonocytic leukemia and RAS-pathway mutations.

9 Jun 2023

Two studies seek to understand the drivers of chronic and progressive phase of COVID-19

Early studies of COVID-19 focused on the acute phase of the disease. However, attention has now turned to the long-term consequences of the disease, which are also significant causes of morbidity and mortality.

6 Jun 2023

Shaping the human metabolome: the impact of a ketogenic diet

Researchers explored how the human metabolic fingerprint changes with a ketogenic diet (KD).

6 Jun 2023

Spice up your heart health: Taurine and black pepper combo shows promising cardioprotective effects

Taurine and black pepper, along with key terpene constituents, are investigated for their potential in reducing cardiovascular risk factors and combating related diseases in this comprehensive literature review. Their cardioprotective effects and mechanisms are explored.

31 May 2023

UTHealth Houston receives federal funding for traumatic brain injury research

Nearly $13 million in federal grant funds to study treatments for traumatic brain injury, which kills an average of 190 people and hospitalizes another 600 in the U.S. every day, has been awarded to UTHealth Houston by the Department of Defense's Office of Congressionally Directed Medical Research Programs (CDMRP).

25 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Researchers investigate the effect of sulfur water baths on rheological blood properties

Researchers evaluated the health benefits of sulfur balneotherapy (sulfur baths) on the rheological properties of the blood of osteoarthritis (OA) patients.

19 May 2023

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) have become established as one of the main treatment options, especially for severe cases, thanks to their anti-inflammatory and immunosuppressant action.

18 May 2023

Platelet News and Research

Cryo-EM study elucidates 3D structure and molecular mechanism of platelet drug transporter

The role of vasomotor reactivity in COVID-19 patients

Could Machine Learning models serve to predict depression in early pregnancy in racial/ethnic minority women?

COVID-19 severity linked to autoantibodies against blood clotting protein

Do Panax notoginseng saponins (Xuesaitong soft capsules) improve function in patients with ischemic stroke?

Study reveals that wine consumption has an inverse relationship to cardiovascular mortality

PREACH-M trial: Lenzilumab may improve treatment response in chronic myelomonocytic leukemia

Two studies seek to understand the drivers of chronic and progressive phase of COVID-19

Shaping the human metabolome: the impact of a ketogenic diet

Spice up your heart health: Taurine and black pepper combo shows promising cardioprotective effects

UTHealth Houston receives federal funding for traumatic brain injury research

Genetic insights unveil promising therapeutic targets for critical COVID-19

Researchers investigate the effect of sulfur water baths on rheological blood properties

Researchers discover how corticosteroids influence inflammatory response during COVID-19 infection

Exploiting platelets for antitumor drug delivery and immune modulation of tumor microenvironment

Evaluating the effect of resveratrol-enriched bread in preventing early type 2 diabetes cardiomyopathy in vivo

Urgent call for improved diagnostics, treatments, and vaccines against deadly Hantavirus

Vein-on-a-chip model can help understand the mechanisms of blood clot formation

Researchers draw attention to the traps in clinical studies on osteoarthritis

An exploration of the pathophysiological factors and abnormalities of coagulation of long-COVID

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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