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Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Recombinant adeno-associated virus (rAAV)-based genetic applications to treat human diseases.

5 Apr 2024

Dietary choices are linked to higher rates of preeclampsia among Latinas

For pregnant Latinas, food choices could reduce the risk of preeclampsia, a dangerous type of high blood pressure, and a diet based on cultural food preferences, rather than on U.S. government benchmarks, is more likely to help ward off the illness, a new study shows.

5 Apr 2024

New study finds interferon-γ release assays more effective than skin tests in predicting tuberculosis

The performance of tuberculin skin test (TST) and interferon-γ release assays (IGRAs) in predicting tuberculosis (TB).

5 Apr 2024

Lancet Commission predicts sharp increase in global prostate cancer cases

Cases of prostate cancer are projected to double from 1.4 million per year in 2020 to 2.9 million per year by 2040, with low- and middle-income countries (LMICs) predicted to see the highest increases in cases, according to The Lancet Commission on prostate cancer which will be launched by a presentation at the European Association of Urology Congress.

4 Apr 2024

Gene therapy and glycoside drugs offer new hope for polycystic kidney disease treatment

Researchers have shown that dangerous cysts, which form over time in polycystic kidney disease (PKD), can be prevented by a single normal copy of a defective gene.

4 Apr 2024

Increased coronary vessel wall thickness linked to heart dysfunction in asymptomatic HIV patients

A new study found increased coronary vessel wall thickness that was significantly associated with impaired diastolic function in asymptomatic, middle-aged individuals living with HIV.

4 Apr 2024

Infertile men more likely to have impaired kidney function, study says

Study reveals that childless men are more likely to have decreased renal function and proteinuria than fathers, suggesting an association between male infertility and higher risks of kidney disease.

4 Apr 2024

Global life expectancy rises by 6.2 years since 1990 despite COVID-19 setbacks

Global life expectancy increased by 6.2 years since 1990 according to a new study published in The Lancet.

3 Apr 2024

Does IBD affect cancer risk?

Research suggests no strong genetic link between inflammatory bowel disease and increased cancer risk, with specific exceptions in European populations for Crohn's disease and ulcerative colitis.

3 Apr 2024

Genetic analysis reveals hidden causes of chronic kidney disease in adults

Chronic kidney disease (CKD) is extremely prevalent among adults, affecting over 800 million individuals worldwide.

3 Apr 2024

Heat protections for California workers are in limbo after Newsom abandons rules

California Gov. Gavin Newsom's administration has abandoned proposed protections for millions of California workers toiling in sweltering warehouses, steamy kitchens, and other dangerously hot workplaces — upending a regulatory process that had been years in the making.

3 Apr 2024

New model predicts kidney injury risk in cancer patients on cisplatin

Researchers have developed a new model predicting severe acute kidney injury in patients treated with cisplatin, incorporating factors like hypomagnesemia to improve patient care and outcomes.

3 Apr 2024

To ban or not to ban, the case for reformulating ultra-processed foods

Despite concerns about ultra-processed foods (UPFs) and non-communicable diseases (NCDs), evidence of causality remains unclear; reformulating UPFs may offer significant health advantages.

1 Apr 2024

Ultra-processed foods raise chronic kidney disease risk, study shows

Consuming ultra-processed foods is linked to an 18% increased risk of chronic kidney disease, with every 10% rise in UPF intake energy contributing to a 7% greater CKD risk.

1 Apr 2024

Childhood BMI tied to higher blood pressure in middle age

Children and teenagers living with overweight or obesity are more likely to have high blood pressure as adults (aged 50-64 years), suggesting the processes behind the condition could begin as early as childhood, suggests new research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May).

1 Apr 2024

Heavy drinkers who cut back see major heart health benefits, study finds

Study shows that heavy drinkers who reduced their alcohol intake experienced a significantly lower risk of major adverse cardiovascular events, underscoring the potential benefits of alcohol reduction on heart health.

31 Mar 2024

Research identifies optimal body weight to reduce cardiovascular risk in diabetes patients

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May), identifies the optimum body weight range for adults with type 2 diabetes to minimize their risk of dying from any cardiovascular disease, including heart failure, heart disease, stroke, and chronic kidney disease.

30 Mar 2024

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Researchers from Lund University in Sweden have identified distinct molecular signatures associated with the clinical signs of sepsis that could provide more accurate diagnosis and prognosis of sepsis, as well as help to target specific therapies at patients who would benefit most, according to new research being presented at this year's European Congress of Clinical Microbiology and Infectious Diseases (ECCMID 2024) in Barcelona, Spain (27-30 April).

30 Mar 2024

Innovative tool could safeguard cancer patients from chemotherapy-induced kidney damage

Using patient data from six major U.S. cancer centers, Brigham researchers and collaborators developed a risk prediction model for moderate-to-severe kidney injury after receiving the chemotherapy drug cisplatin in the largest, first generalizable study of its kind.

30 Mar 2024

Vegan diet benefits individuals with type 1 diabetes, study shows

A low-fat vegan diet rich in fruits, vegetables, grains, and beans reduces insulin needs and improves insulin sensitivity and glycemic control in people with type 1 diabetes, according to a first-of-its-kind study by the Physicians Committee for Responsible Medicine published in Clinical Diabetes.

29 Mar 2024

Kidney News and Research

Adeno-associated virus: The gene therapy revolution faces manufacturing and safety hurdles

Dietary choices are linked to higher rates of preeclampsia among Latinas

New study finds interferon-γ release assays more effective than skin tests in predicting tuberculosis

Lancet Commission predicts sharp increase in global prostate cancer cases

Gene therapy and glycoside drugs offer new hope for polycystic kidney disease treatment

Increased coronary vessel wall thickness linked to heart dysfunction in asymptomatic HIV patients

Infertile men more likely to have impaired kidney function, study says

Global life expectancy rises by 6.2 years since 1990 despite COVID-19 setbacks

Does IBD affect cancer risk?

Genetic analysis reveals hidden causes of chronic kidney disease in adults

Heat protections for California workers are in limbo after Newsom abandons rules

New model predicts kidney injury risk in cancer patients on cisplatin

To ban or not to ban, the case for reformulating ultra-processed foods

Ultra-processed foods raise chronic kidney disease risk, study shows

Childhood BMI tied to higher blood pressure in middle age

Heavy drinkers who cut back see major heart health benefits, study finds

Research identifies optimal body weight to reduce cardiovascular risk in diabetes patients

Scientists identify distinct molecular signatures for sepsis diagnosis and prognosis

Innovative tool could safeguard cancer patients from chemotherapy-induced kidney damage

Vegan diet benefits individuals with type 1 diabetes, study shows

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Why use light scattering to analyze proteins and viral vectors?

Changing the landscape of R&D to build clinical success from the ground up

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