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Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

Understanding the link between EBV-infected B cells and multiple sclerosis

The Wistar Institute's Paul M. Lieberman, Ph.D., and lab team led by senior staff scientist and first author, Samantha Soldan, Ph.D., have demonstrated how B cells infected with the Epstein-Barr virus (EBV) can contribute to a pathogenic, inflammatory phenotype that contributes to multiple sclerosis (MS); the group has also shown how these problematic B cells can be selectively targeted in a way that reduces the damaging autoimmune response of multiple sclerosis.

28 May 2024

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

Vaccinia viruses are therapeutic tools with different biomedical applications depending on the susceptibility characteristics.

24 May 2024

New optogenetics approach may offer better muscle control with less fatigue

For people with paralysis or amputation, neuroprosthetic systems that artificially stimulate muscle contraction with electrical current can help them regain limb function.

23 May 2024

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Ferroptosis, an iron-dependent cell death mechanism, is identified as a key factor in severe COVID-19 lung disease, suggesting potential new therapeutic targets.

22 May 2024

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Hepatocellular carcinoma (HCC), a prevalent form of cancer, profoundly influences the progression and prognosis of the disease through immune response mechanisms.

22 May 2024

Study reveals biological repercussions of UV-C radiation exposure from germicidal lamps

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 9, entitled, "Germicidal lamps using UV-C radiation may pose health safety issues: a biomolecular analysis of their effects on apoptosis and senescence."

22 May 2024

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy and Johns Hopkins Drug Discovery.

21 May 2024

New mechanism discovered for Chagas disease-induced heart damage

Jyothi Nagajyothi, Ph.D. and her laboratory at the Hackensack Meridian Center for Discovery and Innovation (CDI) have identified what may be the main mechanism for how chronic Chagas Disease, a parasitic infection affecting millions of people worldwide, can cause irreversible and potentially fatal heart damage.

20 May 2024

Columbia researchers link ferroptosis to COVID-19 lung disease

In some severe cases of COVID-19, the lungs undergo extreme damage, resulting in a range of life-threatening conditions like pneumonia, inflammation, and acute respiratory distress syndrome.

20 May 2024

Intracellular protein delivery with HyNT stamp system: A leap forward in cancer therapy

The intracellular delivery of proteins is an important technique for unveiling the cellular functions, protein complex structure, and therapeutics. However, the conventional delivery methods have several limitations.

20 May 2024

POSTECH and ImmunoBiome make significant breakthrough in the fight against cancer

A team of POSTECH and ImmunoBiome has made a significant breakthrough in the fight against cancer. Their research, published in the May issue of Nature Immunology (Volume 25, pages790–801,2024), explores a dietary-derived bacterial strain, IMB001.

17 May 2024

Metabolomics study finds biomarkers predicting autism in newborns

A study in Communications Biology utilized metabolomics in newborns to identify markers that might predict autism spectrum disorder (ASD), finding distinct metabolic profiles in children with ASD compared to typically developing children.

14 May 2024

COVID-19 virus can breach blood-retinal barrier, study finds

The blood-retinal barrier is designed to protect our vision from infections by preventing microbial pathogens from reaching the retina where they could trigger an inflammatory response with potential vision loss.

14 May 2024

Research unveils the dual subdomain structure of the centromere

Researchers from the Kops group in collaboration with researchers from the University of Edinburgh, made a surprising new discovery in the structure of the centromere, a structure that is involved in ensuring that chromosomes are segregated properly when a cell divides.

14 May 2024

Breakthrough research reveals potential path toward a cure for ALS

In a groundbreaking Canadian discovery powered by philanthropy, a team of Western University researchers led by Dr. Michael Strong has uncovered a potential path toward a cure for amyotrophic lateral sclerosis (ALS).

13 May 2024

New insights into Chaga mushroom's mechanisms for fighting oral cancer

The mechanisms behind the anti-tumor activity of Chaga mushroom extracts in HSC-4 human oral cancer cells.

13 May 2024

Aerobic exercise proves most effective for combating obesity-related inflammation

New research being presented at this year's European Congress on Obesity (ECO) in Venice, Italy (12-15 May), reveals the anti-inflammatory power of moderate-to-vigorous aerobic exercise in adults living with the low-grade inflammation of obesity, shedding light on its potential to help prevent multiple metabolic diseases including type 2 diabetes and atherosclerosis (clogged arteries).

13 May 2024

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Researchers discovered that venom toxins from African spitting cobras cause severe dermonecrosis, highlighting the need for targeted treatments like the repurposed drug varespladib.

9 May 2024

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Alcohol exposure leads to accumulation of oxidatively damaged proteins in neuronal cells. Differentiated cells are more susceptible to alcohol-induced oxidative protein damage despite higher resistance to cytotoxicity.

9 May 2024

Cell Death News and Research

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Understanding the link between EBV-infected B cells and multiple sclerosis

New immunogenic strain of vaccinia virus unveils potent cancer therapy potential

New optogenetics approach may offer better muscle control with less fatigue

Study reveals ferroptosis as a major driver of severe COVID-19 lung damage

Review highlights the rapidly evolving landscape of hepatocellular carcinoma treatment

Study reveals biological repercussions of UV-C radiation exposure from germicidal lamps

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

New mechanism discovered for Chagas disease-induced heart damage

Columbia researchers link ferroptosis to COVID-19 lung disease

Intracellular protein delivery with HyNT stamp system: A leap forward in cancer therapy

POSTECH and ImmunoBiome make significant breakthrough in the fight against cancer

Metabolomics study finds biomarkers predicting autism in newborns

COVID-19 virus can breach blood-retinal barrier, study finds

Research unveils the dual subdomain structure of the centromere

Breakthrough research reveals potential path toward a cure for ALS

New insights into Chaga mushroom's mechanisms for fighting oral cancer

Aerobic exercise proves most effective for combating obesity-related inflammation

Drug repurposing breakthrough: varespladib curbs snakebite-induced necrosis

Study uncovers alcohol's damaging effects on brain cells through oxidative stress

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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