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New study advocates for de-escalating breast cancer surgery in women aged 55 and older

Surgery involving sentinel lymph node biopsy for middle-aged women with estrogen receptor-positive (ER+) breast cancer may do more harm than good, according to a new study led by University of Pittsburgh and UPMC Hillman Cancer Center researchers.

22 May 2024

100-year-old BCG vaccine protects individuals with type 1 diabetes from infectious diseases

In new research, investigators at Massachusetts General Hospital (MGH) show that the 100-year-old Bacillus Calmette-Guérin (BCG) vaccine, originally developed to prevent tuberculosis, protects individuals with type 1 diabetes from severe COVID-19 disease and other infectious diseases.

22 May 2024

4 ways vaccine skeptics mislead you on measles and more

Measles is on the rise in the United States. So far this year, the number of cases is about 17 times what it was, on average, during the same period in each of the four years before, according to the Centers for Disease Control and Prevention.

22 May 2024

Closed Loop Medicine appoints Paul Johnson as Non-Executive Director

Closed Loop Medicine Ltd., a leading TechBio company developing combination prescription drug plus software therapy products that deliver personalized dose optimization, today announced the appointment of Paul Johnson as an Independent Non-Executive Director.

From Closed Loop Medicine 22 May 2024

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

A novel therapy that reprograms immune cells to promote antitumor activity helped shrink hard-to-treat prostate and bladder cancers in mice, according to research from the Johns Hopkins Kimmel Cancer Center and its Bloomberg~Kimmel Institute for Cancer Immunotherapy and Johns Hopkins Drug Discovery.

21 May 2024

Matcha green tea powder may help keep gum disease bacteria at bay

Periodontitis is an inflammatory gum disease driven by bacterial infection and left untreated it can lead to complications including tooth loss.

21 May 2024

Transformative $8 million donation fuels pancreatic cancer research at WEHI

An exceptional $8 million, 10-year philanthropic investment will spearhead new treatments for pancreatic cancer and create a new dedicated research centre at WEHI.

21 May 2024

Can music therapy improve language development in preterm children by 24 months?

The impact of parent-led, infant-directed singing on language development at 24 months.

21 May 2024

Can a coach-supported mobile health intervention reduce dementia risk?

Whether a coach-supported mHealth intervention can reduce dementia risk factors in high-risk, underserved populations.

21 May 2024

Donepezil fails to enhance cognitive abilities in breast cancer survivors: Phase III trial results

Many breast cancer survivors report cancer-related cognitive impairment following chemotherapy, although prevalence rates and severity vary.

20 May 2024

Dupilumab shows promising results in Phase 3 trial for COPD with type 2 inflammation

Chronic obstructive pulmonary disease patients with type 2 inflammation may soon gain access to a new drug -; dupilumab -; that showed rapid and sustained improvements in patients in a pivotal Phase 3 clinical trial, researchers report in the New England Journal of Medicine.

20 May 2024

Researchers design new regenerative medicine therapy to accelerate diabetic wound repair

Researchers at the Icahn School of Medicine at Mount Sinai have designed a regenerative medicine therapy to speed up diabetic wound repair.

20 May 2024

Breakthrough study shows benefits of diagnosing hidden respiratory diseases

Finding and treating people with undiagnosed asthma or chronic obstructive pulmonary disease (COPD) improved their health and reduced their healthcare visits for respiratory symptoms in the year after diagnosis, according to a world-first clinical trial published in the New England Journal of Medicine.

20 May 2024

Best practices in RF ablation yield excellent outcomes for atrial fibrillation patients

Atrial fibrillation (AF) is the most common form of arrythmia or irregular heartbeat worldwide, impacting millions of people in the U.S. alone.

20 May 2024

Acetaminophen shows potential in preventing acute respiratory distress syndrome, organ injury in sepsis patients

A National Institutes of Health (NIH)-supported clinical trial has found that intravenous acetaminophen reduced sepsis patients' risk of having organ injury or developing acute respiratory distress syndrome, a serious condition that allows fluid to leak into the lungs.

20 May 2024

Insilico and NVIDIA unveil new LLM transformer for solving biological and chemical tasks

In a new paper, researchers from clinical stage artificial intelligence (AI)-driven drug discovery company Insilico Medicine ("Insilico"), in collaboration with NVIDIA, present a new large language model (LLM) transformer for solving biological and chemical tasks called nach0.

20 May 2024

Cancer researchers urged to embrace AI for groundbreaking insights and efficiency

A review in Nature Reviews Cancer emphasizes the necessity for cancer researchers to understand AI's potentials and limitations, detailing its applications and challenges in cancer research to aid non-computational biologists.

20 May 2024

Web-based self-help program proves effective in treating binge eating disorder

Study shows that web-based cognitive behavioral self-help interventions effectively reduce binge eating episodes and improve overall well-being in individuals with binge eating disorder (BED).

19 May 2024

MGH investigators use new drug to save the life of patient with immune thrombotic thrombocytopenic purpura

A team led by investigators from Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, used a new drug to save the life of a patient with immune thrombotic thrombocytopenic purpura (iTTP), a rare disorder characterized by uncontrolled clotting throughout the small blood vessels.

17 May 2024

Vaccine candidate spurs elusive type of broadly neutralizing HIV antibodies

An HIV vaccine candidate developed at the Duke Human Vaccine Institute triggered low levels of an elusive type of broadly neutralizing HIV antibodies among a small group of people enrolled in a 2019 clinical trial.

17 May 2024

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Clinical Trial News and Research

New study advocates for de-escalating breast cancer surgery in women aged 55 and older

100-year-old BCG vaccine protects individuals with type 1 diabetes from infectious diseases

4 ways vaccine skeptics mislead you on measles and more

Closed Loop Medicine appoints Paul Johnson as Non-Executive Director

Novel therapy reprograms immune cells, shrinks prostate and bladder cancers in animal study

Matcha green tea powder may help keep gum disease bacteria at bay

Transformative $8 million donation fuels pancreatic cancer research at WEHI

Can music therapy improve language development in preterm children by 24 months?

Can a coach-supported mobile health intervention reduce dementia risk?

Donepezil fails to enhance cognitive abilities in breast cancer survivors: Phase III trial results

Dupilumab shows promising results in Phase 3 trial for COPD with type 2 inflammation

Researchers design new regenerative medicine therapy to accelerate diabetic wound repair

Breakthrough study shows benefits of diagnosing hidden respiratory diseases

Best practices in RF ablation yield excellent outcomes for atrial fibrillation patients

Acetaminophen shows potential in preventing acute respiratory distress syndrome, organ injury in sepsis patients

Insilico and NVIDIA unveil new LLM transformer for solving biological and chemical tasks

Cancer researchers urged to embrace AI for groundbreaking insights and efficiency

Web-based self-help program proves effective in treating binge eating disorder

MGH investigators use new drug to save the life of patient with immune thrombotic thrombocytopenic purpura

Vaccine candidate spurs elusive type of broadly neutralizing HIV antibodies

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Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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