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New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Genetic screening and counseling slash young adults' excessive drinking, new study reveals

A recent randomized controlled trial found that short-term interventions combining enzyme substances and behavioral changes significantly reduced excessive alcohol intake among young adults.

28 May 2024

Hybrid technique identifies anti-nephrin autoantibodies as biomarker for kidney disorders with nephrotic syndrome

A groundbreaking study, presented today at the 61st ERA Congress, has uncovered a significant breakthrough in the diagnosis and monitoring of kidney diseases associated with nephrotic syndrome.

25 May 2024

Targeting metabolic pathways to combat Epstein-Barr virus infections

The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers.

24 May 2024

Mouse study finds PFAS exposure in fathers disrupts offspring's gene expression

Research reveals that preconception exposure to PFAS in male mice alters sperm methylation and affects gene expression in the liver and fat of their offspring.

23 May 2024

Cherries and berries: Nature’s sweet remedy for a healthy heart

Research paper reviews the cardiovascular benefits of phenolic compounds in cherries and berries, highlighting their potential to reduce inflammation, oxidative stress, and improve lipid profiles. Regular consumption of these fruits can significantly lower the risk of cardiovascular diseases.

23 May 2024

LMU study identifies dual genetic pathways increasing cardiovascular disease risk

LMU researchers have discovered two independent ways by which genetic variants increase the risk of cardiovascular diseases.

22 May 2024

New MOBE technology revolutionizes multiplexed genome editing

The human genome consists of around 3 billion base pairs and humans are all 99.6% identical in their genetic makeup.

21 May 2024

Scientists uncover protein folding secrets through sound

By converting their data into sounds, scientists discovered how hydrogen bonds contribute to the lightning-fast gyrations that transform a string of amino acids into a functional, folded protein.

21 May 2024

Ketogenic diets linked to cellular aging in vital organs, new study finds

Study reveals that ketogenic diets induce cellular senescence in mice, affecting organs like the kidneys and heart through AMPK and p53 pathways. These findings highlight potential long-term risks associated with ketogenic diets.

20 May 2024

Disabling survival pathways could be a promising strategy for brain tumor treatment

When you disable the brakes on a race car, it quickly crashes. Dr. Barak Rotblat wants to do something similar to brain cancer cells.

20 May 2024

Intracellular protein delivery with HyNT stamp system: A leap forward in cancer therapy

The intracellular delivery of proteins is an important technique for unveiling the cellular functions, protein complex structure, and therapeutics. However, the conventional delivery methods have several limitations.

20 May 2024

Breakthrough ATP sensor sheds light on cellular energy dynamics

A molecule called adenosine triphosphate (ATP) is the basic unit of biochemical energy that fuels the activities of all cells.

17 May 2024

MGH investigators use new drug to save the life of patient with immune thrombotic thrombocytopenic purpura

A team led by investigators from Massachusetts General Hospital, a founding member of the Mass General Brigham healthcare system, used a new drug to save the life of a patient with immune thrombotic thrombocytopenic purpura (iTTP), a rare disorder characterized by uncontrolled clotting throughout the small blood vessels.

17 May 2024