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Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

Researchers discovered that Plexin-B1 plays a crucial role in regulating peri-plaque glial nets in Alzheimer’s disease, potentially opening new avenues for treatment by targeting this protein.

29 May 2024

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

A recent study in Nature Medicine found that LM11A-31, targeting the p75 neurotrophin receptor, is safe and shows promise in slowing Alzheimer's disease progression. The trial indicated significant biomarker improvements and potential benefits for further clinical investigation.

28 May 2024

Researchers identify novel way to potentially slow down or halt Alzheimer’s progression

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant breakthrough in Alzheimer's disease research by identifying a novel way to potentially slow down or even halt disease progression.

27 May 2024

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Schizophrenia is a complex disease with variable presentations, and the diverse nature of this mental health disorder has made understanding the mechanisms that cause the disease, and subsequently developing effective treatments, especially challenging.

24 May 2024

Biological similarities found between "chemo brain" and brain fog after COVID-19

Brain fog after COVID-19 is biologically similar to cognitive impairment caused by cancer chemotherapy, something doctors often refer to as "chemo brain."

22 May 2024

CONVINCE trial reveals the effect of long-term colchicine on recurrent stroke and cardiovascular events

In the international CONVINCE trial, presented today (15 May 2024) at the European Stroke Organisation Conference (ESOC) 2024, anti-inflammatory treatment with long-term colchicine did not reduce rates of recurrent stroke and cardiovascular events in patients with non-cardioembolic stroke in the primary intention-to-treat analysis.

16 May 2024

COVID-19 survivors show lasting brain function alterations, fMRI study finds

The long-term impact of coronavirus disease 2019 (COVID-19) on brain function.

14 May 2024

USC study unveils iron as key driver of lung inflammation in allergic asthma

New USC research shows that iron serves as a gas pedal driving certain immune cells that cause inflammation in the lungs during an allergic asthma attack – and blocking or limiting iron may reduce the severity of symptoms.

8 May 2024

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

A study published in Nature Medicine delineates how APOE4 homozygosity distinctly accelerates Alzheimer's disease pathology and biomarkers from the age of 55, suggesting a unique form of the disease and a potential focus for targeted therapies.

8 May 2024

Study shows cows harbor both human and avian flu receptors in their mammary glands

Study investigates the expression of influenza A virus (IAV) receptors in bovine respiratory, cerebral, and mammary tissues, revealing significant localization of human and duck receptors in mammary glands and predominant chicken receptors in the respiratory tract, which may influence the transmission and pathogenesis of IAV in cattle.

8 May 2024

Complex Regional Pain Syndrome treatment shows promise for recovery

Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options. Now, groundbreaking research finds that early detection and effective treatment can lead to significant recovery within 18 months, offering hope to millions of people worldwide.

6 May 2024

Study reveals how photobiomodulation improves cognitive alterations from chronic stress

Some neurological disorders can be improved through photobiomodulation, a non-invasive technique based on the application of low-intensity light to stimulate altered functions in specific regions of the body.

2 May 2024

Study links agricultural pesticide exposure to increased genetic variants in Parkinson’s disease

Genetic characteristics that influence the risk of Parkinson's disease (PD) due to pesticide exposure.

1 May 2024

Research offers hope to millions of people with complex regional pain syndrome

Complex Regional Pain Syndrome (CRPS) is a chronic and debilitating pain disorder, typically considered lifelong with limited treatment options.

30 Apr 2024

Study investigates the potential effects of neonatal vitamin D on eczema up to adulthood

Australian researchers find that higher neonatal vitamin D levels are associated with lower odds of early-onset persistent eczema but an increased risk of early-onset resolving eczema in children up to age 25.

30 Apr 2024

Antioxidant-rich diets linked to better life quality in young women with acne

A study published in the Nutrients journal finds that a high dietary antioxidant quality index (DAQI) can significantly enhance the quality of life for young women with acne vulgaris by reducing acne severity and associated depression risks.

28 Apr 2024

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

A review in Nature Reviews Nephrology presents the association between immune cells and the development of hypertension, suggesting potential new therapeutic targets to mitigate the disease by managing inflammation.

26 Apr 2024

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

A team of researchers at Johannes Gutenberg University Mainz (JGU) has identified a mechanism that causes mitochondrial dysfunction in Alzheimer's patients resulting in a reduction of the supply of energy to the brain.

25 Apr 2024

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

A study examining 1031 hospitalized COVID-19 patients found that aging significantly impacts immune responses, viral dynamics, and the nasal microbiome, with older adults experiencing more severe disease symptoms and delayed viral clearance.

18 Apr 2024

Are we eating what's really good for us? New insights into macronutrients and chronic disease

Review explores the impact of macronutrients like carbohydrates, proteins, and fats on health, emphasizing the need for precision in dietary guidance to manage and prevent chronic diseases effectively.

11 Apr 2024

Pathophysiology News and Research

Study finds Plexin-B1 could be key to Alzheimer’s treatment, enhancing glial cell response

New Alzheimer's drug LM11A-31 shows promise in slowing disease progression in clinical trial

Researchers identify novel way to potentially slow down or halt Alzheimer’s progression

Study sheds new light on the intricate molecular mechanisms underlying schizophrenia

Biological similarities found between "chemo brain" and brain fog after COVID-19

CONVINCE trial reveals the effect of long-term colchicine on recurrent stroke and cardiovascular events

COVID-19 survivors show lasting brain function alterations, fMRI study finds

USC study unveils iron as key driver of lung inflammation in allergic asthma

APOE4 gene linked to early onset Alzheimer's, target for therapeutic intervention

Study shows cows harbor both human and avian flu receptors in their mammary glands

Complex Regional Pain Syndrome treatment shows promise for recovery

Study reveals how photobiomodulation improves cognitive alterations from chronic stress

Study links agricultural pesticide exposure to increased genetic variants in Parkinson’s disease

Research offers hope to millions of people with complex regional pain syndrome

Study investigates the potential effects of neonatal vitamin D on eczema up to adulthood

Antioxidant-rich diets linked to better life quality in young women with acne

Immune cells play a bigger role in high blood pressure than previously thought, opening doors for new treatments

Researchers uncover mechanism behind mitochondrial dysfunction in Alzheimer's

Aging affects immune response and virus dynamics in COVID-19 patients, study finds

Are we eating what's really good for us? New insights into macronutrients and chronic disease

Changing the landscape of R&D to build clinical success from the ground up

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

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