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Existing drug alleviates symptoms of a rare genetic syndrome

A drug approved to treat certain autoimmune diseases and cancers successfully alleviated symptoms of a rare genetic syndrome called autoimmune polyendocrine syndrome type 1 (APS-1).

30 May 2024

Researchers overturn the prevailing theory for colorectal tumor initiation

Research led by Weill Cornell Medicine provides new evidence that most colorectal cancers begin with the loss of intestinal stem cells, even before cancer-causing genetic alterations appear.

29 May 2024

Evaluating the efficacy of harmol in treating herpes simplex virus-induced keratitis

The antiviral efficacy and therapeutic potential of harmol in treating herpes simplex virus type 1 (HSV-1) induced keratitis

29 May 2024

Phytochemicals show promise in treating neurological disorders by influencing the gut-brain axis

Researchers reviewed the potential therapeutic effects of phytochemicals on the gut-brain axis, finding they could influence brain function and reduce neurological symptoms by modulating gut microbiota.

26 May 2024

Study sheds light on intricate differences in the brains of people with PTSD and depression

Stress-related disorders like post-traumatic stress disorder and clinical depression are complex conditions influenced by both genetics and our environment.

23 May 2024

Breakthrough study reveals molecular drivers of Alzheimer's progression

According to the US Centers for Disease Control and Prevention, at least 5.8 million Americans are currently living with Alzheimer's disease, which is the most common form of dementia.

23 May 2024

New study identifies key protein biomarkers for early detection of pancreatic cancer

Study used a Mendelian randomization approach to identify REG1A and REG1B as potential biomarkers for early detection of pancreatic cancer, showing their causal effects and significance in cancer screening.

19 May 2024

SMART researchers identify key mechanism behind artemisinin resistance in malaria

Researchers from the Antimicrobial Resistance (AMR) Interdisciplinary Research Group (IRG) at Singapore-MIT Alliance for Research and Technology (SMART), MIT's research enterprise in Singapore, in collaboration with Massachusetts Institute of Technology (MIT), Columbia University Irving Medical Center (CUIMC), and Nanyang Technological University, Singapore (NTU Singapore), have discovered a link between malaria parasites' ability to develop resistance to antimalarial drugs – specifically artemisinin (ART) – through a cellular process called transfer Ribonucleic acid (tRNA) modification.

16 May 2024

Novel bispecific antibodies show promise against evolving SARS-CoV-2 variants

Researchers developed bispecific antibodies targeting both the N-terminal and receptor binding domains of SARS-CoV-2, demonstrating significant neutralization across various Omicron variants, suggesting potential for new COVID-19 treatments.

9 May 2024

Clinical trial shows CRISPR gene editing has exciting potential to treat a rare form of blindness

A recent study published in The New England Journal of Medicine investigated the potential use of gene editing to correct a congenital retinal degeneration called CEP290 that causes early-onset vision loss.

8 May 2024

Nuclera eProtein Discovery system installed at leading academic institutes

Novel platform automates and accelerates protein production, enabling scale-up to mg amount in less than 48 hours.

From Nuclera 2 May 2024

Study investigates senescent phenotypes of human corneal endothelial cells upon UV-A exposure

A new research paper was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Senescent characteristics of human corneal endothelial cells upon ultraviolet-A exposure."

30 Apr 2024

DELiVR's virtual reality training speeds up cell detection in complex brain datasets

Efficient neuronal activity detection in brain imaging.

25 Apr 2024

Study highlights how age affects nasal cell response to SARS-CoV-2

Researchers reveal age-related differences in nasal epithelial cell responses to SARS-CoV-2, showing variations in cell types and viral dynamics across pediatric, adult, and older adult groups.

16 Apr 2024

Combining blood pressure drug with dietary-resistant starch may help stave off diabetic kidney disease

Combining a low dose of blood pressure medication with a higher intake of dietary-resistant starch might help stave off diabetic kidney disease, according to results from a new animal study.

7 Apr 2024

Study highlights anti-inflammatory properties of herbal medicine, Erigeron breviscapus to treat osteoarthritis

Researchers explored using Erigeron breviscapus (EB) as a treatment for osteoarthritis (OA).

4 Apr 2024

Lurie Children's Hospital administers first gene therapy for Duchenne muscular dystrophy in Illinois

On March 27, 2024, Ann & Robert H. Lurie Children's Hospital of Chicago treated its first patient with ELEVIDYS (delandistrogene moxeparvovec-rokl), the first gene therapy for Duchenne muscular dystrophy – a rare, genetic disease characterized by progressive muscle damage and weakness.

3 Apr 2024

Newly discovered molecule may be a potential therapeutic target for triple-negative breast cancer

A team of researchers from Hiroshima University has discovered a molecule that promotes the production of cancer cells. This molecule may prove to be a potential therapeutic target in the treatment of triple-negative breast cancer, an aggressive form of breast cancer.

27 Mar 2024

Researchers identify new potential target for the treatment of Alzheimer's disease

Researchers at the University of Leeds and Lancaster University in the UK have identified a new potential target for the treatment of Alzheimer's disease – PDE4B.

26 Mar 2024

Nuclera joins Tech Nation’s Future Fifty program

Nuclera recognized as one of UK’s most exciting growth stage companies.

From Nuclera 20 Mar 2024