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Antiviral hope emerges as viruses linked to multiple myeloma

A few years ago, a patient was cured of multiple myeloma after being treated for hepatitis C, astounding researchers from the group led by Joaquín Martínez, from the H12O-CNIO Haematological Tumours Clinical Research Unit, a collaboration between the Hospital 12 de Octubre (H12O) and the National Cancer Research Centre (CNIO).

19 Jan 2024

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Researchers use a mathematical model to assess the efficacy of a new combinational therapy of AZD9496 and palbociclib for breast cancer treatment.

18 Jan 2024

Revolutionary brain scan lights up glioma's Achilles heel

Recently, a team of South Korean researchers led by nuclear medicine physician and Professor Yun Mijin from Severance Hospital in collaboration with Director C. Justin LEE of the Center for Cognition and Sociality within the Institute for Basic Science (IBS) made a new discovery that can revolutionize both the diagnosis and treatment of glioblastoma.

16 Jan 2024

Scientists identify critical protein complex for targeted cancer treatment

The repair of damage to genetic material (DNA) in the human body is carried out by highly efficient mechanisms that have not yet been fully researched.

11 Jan 2024

Collaborative effort to develop AI-powered tools for glioma detection

Each year, about 22,000 individuals in the EU are diagnosed with a glioma, a malignant type of brain tumor. Median survival time after diagnosis can be as short as 15 months.

5 Jan 2024

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

A new study in Nature described Nav1.7 as a key regulatory molecule in cartilage cells and reported the effectiveness of Nav1.7 blockade in reducing pain and slowing progression in OA.

5 Jan 2024

COVID-19's unseen impact: study reveals surge in home deaths across 32 countries

Trends in places of death across 32 countries during and before the COVID-19.

5 Jan 2024

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

A detailed 'atlas' of neuroblastoma tumors points to a new target for immunotherapy. Scientists from the Princess Máxima Center for Pediatric Oncology in the Netherlands mapped this childhood tumor at the level of individual cancer and immune cells.

4 Jan 2024

HPV infection linked to doubled risk of thyroid cancer

A study in Taiwan involving 3,062 thyroid cancer patients and 9,186 controls finds that HPV infection more than doubles the risk of developing thyroid cancer, providing the first evidence of a carcinogen for this common endocrine cancer.

4 Jan 2024

Researchers establish the first international criteria for standardized imaging of gliomas

Diffuse gliomas are malignant brain tumors and cannot be optimally examined by conventional imaging using MRI. Amino acid PET can better visualize the activity and spread of gliomas.

3 Jan 2024

New standardized criteria for diagnosing brain tumors with amino acid PET

Diffuse gliomas are malignant brain tumors that cannot be optimally examined by means of conventional MRI imaging. So-called amino acid PET scans are better able to image the activity and spread of gliomas.

3 Jan 2024

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

A new research paper was published in Oncotarget's Volume 14 on December 20, 2023, entitled, "The pharmacodynamic and mechanistic foundation for the antineoplastic effects of GFH009, a potent and highly selective CDK9 inhibitor for the treatment of hematologic malignancies."

28 Dec 2023

New drug screening system helps uncover promising target for pancreatic cancer treatments

A drug screening system that models cancers using lab-grown tissues called organoids has helped uncover a promising target for future pancreatic cancer treatments, according to a new study from researchers at Weill Cornell Medicine.

26 Dec 2023

Study highlights underutilization of end-of-life care for patients with malignant urinary obstruction

Less than half of patients with malignant ureteral obstruction (MUO) – a serious complication of advanced cancer, with a poor prognosis – receive palliative care (PC) for their condition, reports a paper in the January issue of Urology Practice, an Official Journal of the American Urological Association (AUA).

21 Dec 2023

Rapid identification of disease-causing bacteria using Raman spectroscopy

Study in BioRisk explores the use of Raman spectroscopy for rapid identification of Pseudomonas aeruginosa, a bacteria causing serious human diseases, demonstrating its potential as a quick and efficient diagnostic tool.

14 Dec 2023

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

In recent years, cancer immunotherapies have established themselves as a further pillar of medical oncology alongside traditional treatment options (surgery, radiotherapy and chemotherapy).

13 Dec 2023

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Researchers performed a molecular analysis of neuroendocrine neoplasm (NEN) patient-derived tumor organoids (PDTOs) and their parental neoplasms.

13 Dec 2023

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Lymphatic fluid from surgical drains, which is usually tossed in the trash, is a treasure in the hands of University of Pittsburgh and Washington University School of Medicine in St. Louis researchers who found that this liquid could inform more precise treatments for patients with head and neck cancer caused by human papillomavirus (HPV).

11 Dec 2023

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

The targeted therapy bezuclastinib was safe and rapidly reduced markers of disease burden while also improving symptoms for patients with a rare blood disorder called nonadvanced system mastocytosis, according to results of the Phase II SUMMIT trial reported by researchers at The University of Texas MD Anderson Cancer Center.

11 Dec 2023

The association between viral infections and glioma risk

The causal relationship between viral infection and glioma.

7 Dec 2023

Malignant News and Research

Antiviral hope emerges as viruses linked to multiple myeloma

Mathematical modeling demonstrates efficacy of combinational drug therapy for breast cancer treatment

Revolutionary brain scan lights up glioma's Achilles heel

Scientists identify critical protein complex for targeted cancer treatment

Collaborative effort to develop AI-powered tools for glioma detection

Epilepsy drug may alleviate joint degeneration associated with osteoarthritis

COVID-19's unseen impact: study reveals surge in home deaths across 32 countries

High-resolution map of the neuroblastoma immune landscape points to new target for immunotherapy

HPV infection linked to doubled risk of thyroid cancer

Researchers establish the first international criteria for standardized imaging of gliomas

New standardized criteria for diagnosing brain tumors with amino acid PET

GFH009 disrupts growth signals and triggers apoptosis in hematologic malignancies

New drug screening system helps uncover promising target for pancreatic cancer treatments

Study highlights underutilization of end-of-life care for patients with malignant urinary obstruction

Rapid identification of disease-causing bacteria using Raman spectroscopy

Developing a virtual twin for personalized cancer treatment with CAR-T cell therapy

Organoid study opens new avenues in pulmonary neuroendocrine cancer therapy

Lymphatic fluid from surgical drains could inform more precise treatments for head and neck cancer

Targeted therapy reduces markers of disease burden, improves symptoms for patients with nonadvanced system mastocytosis

The association between viral infections and glioma risk

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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