Fatty Liver

Fatty liver, also known as fatty liver disease (FLD), is a reversible condition where large vacuoles of triglyceride fat accumulate in liver cells via the process of steatosis (i.e. abnormal retention of lipids within a cell).

What is Fatty Liver?

Fatty liver is a very common disorder and up to 20 percent of adults and approximately 5 percent of children are affected.

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Liver function discovery could revolutionize treatments for cardiovascular disease

A new discovery about how the liver flushes cholesterol from the body could lead to more effective treatments for cardiovascular disease – the leading cause of death worldwide.

18 Oct 2024

New grant aims to transform treatment for liver cancer

Currently, there are a few available treatment options for liver cancer, including a combination of immunotherapies and a class of drugs known as tyrosine kinase inhibitors (TKIs), but their long-term effects are limited.

17 Oct 2024

Semaglutide improves heart health and reduces weight in obese patients, but with side effects

Semaglutide significantly reduces cardiovascular events and adverse effects in overweight and obese patients. The study highlights semaglutide's superiority over other GLP-1 agonists for cardiovascular health.

14 Oct 2024

New research explores hydrogen sulfide as treatment for obesity

Therapies that deliver hydrogen sulfide to cells could one day become the basis of new treatments for obesity and related diseases, new research has concluded.

10 Oct 2024

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

Research explores how excessive sugar consumption can drive systemic inflammation, disrupt the gut and oral microbiomes, and contribute to periodontal inflammation, with implications for global health.

10 Oct 2024

New research offers hope for treating metabolic dysfunction-associated liver disease

Metabolic dysfunction-associated steatotic liver disease (MASLD) — previously known as "non-alcoholic fatty liver disease" — affects about 25% of the global population.

9 Oct 2024

Study sheds light on a potential new strategy to prevent fatty liver

The accumulation of fats in the liver is driven by high-fat diets and obesity, and is becoming an increasingly prevalent global health concern.

7 Oct 2024

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

Researchers uncovered 1,307 genetic loci linked to metabolic syndrome, revealing brain tissue enrichment and key genetic factors in its development. The study also shows polygenic risk scores predict metabolic syndrome across populations.

1 Oct 2024

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

Research indicates that high flavonoid intake is linked to a lower risk of NAFLD, with apples and tea showing significant protective effects on liver health.

30 Sep 2024

New pipeline of drug candidates offers hope for effective MASLD treatments

Non-alcoholic fatty liver disease (NAFLD), recently reclassified as metabolic dysfunction-associated steatotic liver disease (MASLD), has become the most prevalent chronic liver disease globally.

25 Sep 2024

Targeted obesity programs reduce lipid-related heart disease risk in children

Researchers assess the lipid profiles of obese children and adolescents and their health implications.

24 Sep 2024

Yoyo dieting alters gut health, driving weight regain and inflammation

Researchers from Deakin University reveal how yoyo dieting disrupts gut health, leading to weight regain and obesity-related complications. The study highlights the roles of gut microbiota, hormones, and inflammation in the weight cycling process.

23 Sep 2024

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

Scientists from the University of Copenhagen have detected lipid biomarkers in children and teenagers with obesity that indicate an increased risk of developing type 2 diabetes, liver and heart disease as adults.

20 Sep 2024

New blood test identifies obesity-related health risks in children

A new type of blood test using lipids could make it easier to identify children at risk of complications around obesity including type two diabetes, liver and heart disease, say scientists.

20 Sep 2024

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

A study led by Manuel Vázquez Carrera, group leader at the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM) at the University of Barcelona, reveals advances in the understanding and treatment of liver fibrosis, a serious complication in the context of metabolic fatty liver disease, also known as MASLD (metabolic dysfunction-associated steatotic liver disease).

17 Sep 2024

Higher soft drink consumption linked to increased risk of liver disease

Study found that higher soft drink consumption is associated with an increased risk of nonalcoholic fatty liver disease, especially in males, within a cohort of Mexican adults.

16 Sep 2024

New IndiPHARM initiative aims to revolutionize personalized medication management

A Columbia University-led multicenter research effort called IndiPHARM: individual metabolome and exposome assessment for pharmaceutical optimization will develop a platform and monitoring system to prevent unwanted interactions between medications and other environmental, genetic, and lifestyle factors, in order to optimize therapeutic efficacy.

12 Sep 2024

Brazilian research uncovers how liver nerves regulate glucose production under stress

A study led by Brazilian researchers has produced a detailed description of the morphology of the nerves in the liver and how they control production of glucose when the organism is under stress.

11 Sep 2024

A promising new therapeutic target for MASLD identified

Using a novel stem cell platform, a team of the Medical University of South Carolina researchers has identified a pathway that could be targeted by drugs to reduce fat accumulation in patients with a common form of fatty liver disease known as metabolic dysfunction-associated steatotic liver disease, or MASLD.

11 Sep 2024

Long-term exercise leads to healthier fat storage in obese individuals

People with obesity who are long-time exercisers have healthier belly fat tissue and can store fat there more effectively than nonexercisers with obesity, according to a new study from a team of researchers at the University of Michigan.

10 Sep 2024

Fatty Liver

Overview

Fatty Liver Pathology

Fatty Liver Diagnosis

Acute Fatty Liver of Pregnancy Treatment

Latest Fatty Liver News and Research

Liver function discovery could revolutionize treatments for cardiovascular disease

New grant aims to transform treatment for liver cancer

Semaglutide improves heart health and reduces weight in obese patients, but with side effects

New research explores hydrogen sulfide as treatment for obesity

Excess sugar consumption triggers inflammation and dysbiosis, worsening periodontal disease

New research offers hope for treating metabolic dysfunction-associated liver disease

Study sheds light on a potential new strategy to prevent fatty liver

Genetic study uncovers key drivers of metabolic syndrome with brain tissue links

The consumption of flavonoid-rich foods was associated with a reduced risk of NAFLD among middle-aged adults

New pipeline of drug candidates offers hope for effective MASLD treatments

Targeted obesity programs reduce lipid-related heart disease risk in children

Yoyo dieting alters gut health, driving weight regain and inflammation

Lipid biomarkers in children with obesity linked to future cardiometabolic risks

New blood test identifies obesity-related health risks in children

Activation of PPARβ/δ-AMPK pathway shown to slow liver fibrosis development

Higher soft drink consumption linked to increased risk of liver disease

New IndiPHARM initiative aims to revolutionize personalized medication management

Brazilian research uncovers how liver nerves regulate glucose production under stress

A promising new therapeutic target for MASLD identified

Long-term exercise leads to healthier fat storage in obese individuals

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

Fatty Liver

Overview

Latest Fatty Liver News and Research

Shaping the Future of Neuroscience: A Conversation with Atlas Antibodies on the MolBoolean™ and the Impact of SfN 2024

How the Arts Reshape Brain Function: Susan Magsamen on the Future of Neuroaesthetics

Inside the Alzheimer's Association: Dr. Heather Snyder on Driving Research and Collaboration

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