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Promising gene editing therapy shows hope in sickle cell disease cure

Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.

14 Jun 2024

New therapeutic approach for Duchenne muscular dystrophy combines LED therapy with idebenone

In an animal model of Duchenne muscular dystrophy, Brazilian researchers tested a therapy that combines photobiomodulation using laser light or light-emitting diodes (LEDs) with idebenone, an antioxidant compound investigated for application in neurodegenerative diseases.

14 Jun 2024

The hidden genetic switches influencing human height and bone health

In mammals, only 3% of the genome consists of coding genes which, when transcribed into proteins, ensure the biological functions of the organism and the in-utero development of future individuals. But genes do not function alone.

14 Jun 2024

MEK inhibitor trametinib shows potential in pediatric JMML treatment

The MEK inhibitor trametinib (Mekinist) was an effective treatment for pediatric patients with relapsed or refractory juvenile myelomonocytic leukemia (JMML) enrolled in a phase II clinical trial, with seven of 10 patients alive after a median of two years.

13 Jun 2024

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

A large study by researchers at Stanford Medicine has found that the risk of secondary blood cancers after CAR-T cell therapy -; a cell-based cancer treatment that exploded on the scene in 2017 as a treatment for intractable blood cancers -; is low, despite a Food and Drug Administration warning.

12 Jun 2024

Germ cells drive sex-dependent lifespan differences in vertebrate animals

Women live longer than men. This isn't unique to humans, either; we see this trend in a wide range of other animals.

12 Jun 2024

Chronic kidney disease may be linked with tooth loss in postmenopausal women

Kidneys play a critical role in overall health by removing waste products from the blood. When they fail to sufficiently filter out foreign elements, several serious, lifethreatening, medical conditions can result.

12 Jun 2024

Natural antioxidants could delay age-related decline in male testosterone production

Natural polyphenolic compounds to enhance testosterone production and prevent age-related hypogonadism in aging males.

12 Jun 2024

Microgravity and galactic radiation: Dual threats to astronaut kidney health

The structure and function of the kidneys is altered by space flight, with galactic radiation causing permanent damage that would jeopardize any mission to Mars, according to a new study led by researchers from UCL.

11 Jun 2024

Teprotumumab shows long-lasting benefits for thyroid eye disease patients

Most patients with thyroid eye disease treated with teprotumumab didn't require additional treatments nearly 2 years later, according to industry-supported research being presented Sunday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass., and published in the journal Thyroid.

10 Jun 2024

Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

In a world-first, Australian researchers and clinicians have shown that precision medicine – where treatment is tailored to an individual child's cancer – leads to significantly improved outcomes in children with high risk cancer.

6 Jun 2024

Proteomic fitness scores revolutionize disease prediction and personalized exercise plans

Research establishes a proteomic CRF score, linking it to improved prediction of mortality and multisystem disease risks, showing dynamic response to exercise training.

5 Jun 2024

$Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery$

Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery

Antibiotic treatment prior to surgical repair of a pediatric elbow fracture does not reduce the risk for post-operative infection, according to new findings from a team of researchers and surgeons from the University of Missouri School of Medicine.

5 Jun 2024

Unveiling the heterogeneity of skeletal stem cells across skeletal regions and developmental stages

SSCs are essential for bone development, homeostasis, and repair. Recent studies have identified distinct SSC populations in long bones, craniofacial bones, and spine.

5 Jun 2024

End of pandemic internet subsidies threatens a health care lifeline for rural America

Myrna Broncho realized just how necessary an internet connection can be after she broke her leg.

5 Jun 2024

Applied Cells releases game-changing reagent kits to empower cell therapy development

Applied Cells is excited to announce the launch of its MARS® Ingenuity™ Reagent kits for fast and easy cell isolation. This innovative product line features both RUO and GMP-grade reagents, and has been specifically optimized for use on Applied Cells’ proprietary MARS® Bar platform.

From Applied Cells 4 Jun 2024

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Researchers found that young bone marrow transplants rejuvenate aging immune cells, reducing Alzheimer's symptoms in mice models, suggesting a potential therapeutic approach for the disease.

4 Jun 2024

Endocrine Society issues new clinical practice guideline on vitamin D use and testing

Healthy adults under the age of 75 are unlikely to benefit from taking more than the daily intake of vitamin D recommended by the Institutes of Medicine (IOM) and do not require testing for vitamin D levels, according to a new Clinical Practice Guideline issued today by the Endocrine Society.

3 Jun 2024

Pre-pregnancy weight loss surgery type may affect child's early weight gain

The type of weight loss surgery women undergo before becoming pregnant may affect how much weight their children gain in the first three years of life, suggests a study being presented Monday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Telemedicine boosts equitable access to endocrinology care for patients with diabetes and heart disease

Widespread availability of telemedicine during the pandemic led to more equitable access to endocrinology care for patients with type 2 diabetes and heart disease, according to a study being presented Monday at ENDO 2024, the Endocrine Society's annual meeting in Boston, Mass.

3 Jun 2024

Bone News and Research

Promising gene editing therapy shows hope in sickle cell disease cure

New therapeutic approach for Duchenne muscular dystrophy combines LED therapy with idebenone

The hidden genetic switches influencing human height and bone health

MEK inhibitor trametinib shows potential in pediatric JMML treatment

Stanford study finds low risk of secondary blood cancers after CAR-T cell therapy

Germ cells drive sex-dependent lifespan differences in vertebrate animals

Chronic kidney disease may be linked with tooth loss in postmenopausal women

Natural antioxidants could delay age-related decline in male testosterone production

Microgravity and galactic radiation: Dual threats to astronaut kidney health

Teprotumumab shows long-lasting benefits for thyroid eye disease patients

Precision medicine revolutionizes outcomes for high-risk pediatric cancer patients

Proteomic fitness scores revolutionize disease prediction and personalized exercise plans

Preoperative antibiotic treatment does not reduce infection risk after pediatric elbow fracture surgery

Unveiling the heterogeneity of skeletal stem cells across skeletal regions and developmental stages

End of pandemic internet subsidies threatens a health care lifeline for rural America

Applied Cells releases game-changing reagent kits to empower cell therapy development

Young bone marrow transplants show promise in reversing Alzheimer's symptoms in mice

Endocrine Society issues new clinical practice guideline on vitamin D use and testing

Pre-pregnancy weight loss surgery type may affect child's early weight gain

Telemedicine boosts equitable access to endocrinology care for patients with diabetes and heart disease

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From Discovery Biology to ELRIG Chair

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