Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

Life's Essential 8: key to reducing heart disease and mortality through epigenetics

Whether DNA methylation-based epigenetic age biomarkers mediate the associations between LE8 score and risks of CVD, CVD-specific mortality, and all-cause mortality.

31 May 2024

RNA interference agent plozasiran targets APOC3 for effective mixed hyperlipidemia treatment

Researchers evaluate the efficacy of plazosiran treatment on fasting triglyceride levels in adult patients with mixed hyperlipidemia.

31 May 2024

New antibiotic lolamicin shows promise in fighting drug-resistant infections

Researchers have developed a new antibiotic that reduced or eliminated drug-resistant bacterial infections in mouse models of acute pneumonia and sepsis while sparing healthy microbes in the mouse gut.

29 May 2024

RNA-based therapy shows promise in reducing cholesterol and triglycerides

A small interfering RNA (siRNA) investigational therapy that inhibits a gene involved in lipoprotein metabolism has been shown in a clinical trial led by Mount Sinai researchers to significantly reduce levels of different types of cholesterol and triglycerides in individuals with mixed hyperlipidemia, a condition in which fats build up in the blood.

29 May 2024

Oral semaglutide shows promising results for type 2 diabetes in routine clinical settings

Semaglutide and its effects on glycemic control, body weight (BW), and tolerability in routine clinical practice.

28 May 2024

Ketogenic diet improves metabolic and mental health in schizophrenia and bipolar disorder patients, study finds

Researchers found that a ketogenic diet significantly improves both metabolic and psychiatric health in individuals with schizophrenia or bipolar disorder, with notable reductions in weight, waist circumference, and mental illness severity.

27 May 2024

Running therapy matches antidepressants for mental health, surpasses for physical benefits

Researchers found that while both antidepressants and group running therapy effectively improved mental health in patients with anxiety and depression, running therapy had significantly better outcomes for physical health indicators.

26 May 2024

Are ultraprocessed foods putting your child's heart at risk?

Associations between ultra-processed food (UPF) consumption and cardiometabolic risk factors in young children.

22 May 2024

Global study highlights major health risks: air pollution and high blood pressure top the list

A comprehensive study in The Lancet reveals the global health impacts of 88 risk factors, emphasizing the significant burden of air pollution and high blood pressure.

21 May 2024

Taurine supplementation shows promise in reducing metabolic syndrome risk factors, study finds

A study in Nutrition & Diabetes meta-analyzed randomized clinical trials and found that taurine supplementation significantly reduces key risk factors for metabolic syndrome, such as high blood pressure, fasting blood glucose, and triglycerides, with no notable adverse effects.

20 May 2024

Body fat percentage beats BMI in predicting obesity-related health risks, study says

A study in the Journal of Clinical Endocrinology & Metabolism found that body fat percentage (%BF) thresholds are more accurate than BMI for predicting obesity-related health conditions, suggesting new standards for defining overweight and obesity.

19 May 2024

Plant-based diets reduce cancer and heart disease risks, study shows

Study reveals that plant-based diets significantly reduce the risks of cancer and cardiometabolic diseases while improving overall health markers.

16 May 2024

Metabolomic analysis sheds light on gut microbes' role in cardiovascular disease risk

The effect of gut bacteria on non-high-density lipoprotein cholesterol (non-HDL-c) variations.

14 May 2024

Personalized dietary programs outperform general advice for better heart health

Study found that personalized dietary programs (PDP) led to significant improvements in cardiometabolic health compared to standard dietary advice, with notable reductions in weight, triglyceride levels, and waist circumference.

13 May 2024

Underdiagnosed and common: Study highlights neuropathy's hidden toll

Neuropathy, the nerve damage that causes pain and numbness in the feet and hands and can eventually lead to falls, infection and even amputation, is very common and underdiagnosed, according to a study published in the May 8, 2024, online issue of Neurology, the medical journal of the American Academy of Neurology.

8 May 2024

Exploring associations between NMR-measured biomarkers and accelerated aging in cardiac catheterization patients

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Associations among NMR-measured inflammatory and metabolic biomarkers and accelerated aging in cardiac catheterization patients."

7 May 2024

Increase in sedentary time from childhood associated with progressing heart enlargement

An increase in sedentary time from childhood caused progressing heart enlargement, a new study shows. However, light physical activity could reduce the risk.

7 May 2024

Nutritional interventions for type 2 diabetes management with glycemic control

Researchers explore the effects of healthy diet interventions on various body mass and cardiometabolic parameters.

6 May 2024

Can monitoring and encouraging physical activity through phone-based apps improve glycemic control and weight loss in type 2 diabetes patients?

Whether a smartphone application (app) for maintaining personal health records encouraged physical activity, improved step counts, and glycemic control.