Carcinoma News and Research

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Carcinoma is cancer that begins in the skin or in tissues that line or cover internal organs.

Rare variants in the YKT6 gene cause new neurological disorder, study finds

A recent collaborative study has discovered rare variants in the YKT6 gene as the cause of a new neurological disorder characterized by developmental delays along with severe progressive liver disease and a potential risk for liver cancer.

1 Apr 2024

Study provides a hopeful direction for the management of penile squamous cell carcinoma

In a recent multi-center study published in the Journal of the National Cancer Institute, researchers examined the effects of neoadjuvant chemotherapy (NAC) on patients suffering from locally advanced penile squamous cell carcinoma (PSCC).

28 Mar 2024

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

A study assessed the effect of tobacco smoking and electronic cigarette (e-cigarettes) use on DNA methylation changes associated with carcinogenesis.

25 Mar 2024

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

New data from the KEYNOTE-756 phase 3 clinical trial show that adding the immunotherapy drug, pembrolizumab, to chemotherapy before and after surgery for breast cancer leads to better outcomes for patients regardless of their age or menopausal status.

20 Mar 2024

Immune cell protein identified as potential target for rare liver cancer treatment

Fibrolamellar carcinoma (FLC) is a rare liver cancer with a poor prognosis if not addressed early with surgery. The disease is caused by a single genetic mutation that creates a fusion protein.

20 Mar 2024

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

A study aiming to develop a Lipid nanoparticles (LNP) platform for treating oral squamous cell carcinoma (OSCC) utilizing p53 mRNA was presented at the 102nd General Session of the IADR, which was held in conjunction with the 53rd Annual Meeting of the American Association for Dental, Oral, and Craniofacial Research and the 48th Annual Meeting of the Canadian Association for Dental Research, on March 13-16, 2024, in New Orleans, LA, USA.

19 Mar 2024

New insights into upper tract urothelial carcinoma evolution and treatment

Researchers at Weill Cornell Medicine have performed the most comprehensive analysis to date of cancer of the ureters or the urine-collection cavities in the kidney, known as upper tract urothelial carcinoma (UTUC).

18 Mar 2024

Researchers develop an algorithm to identify high-risk precancerous lesions on the fallopian tubes

Researchers at the Johns Hopkins Kimmel Cancer Center and the Department of Gynecology and Obstetrics at the Johns Hopkins University School of Medicine have developed an algorithm to identify high-risk precancerous lesions on the fallopian tubes.

14 Mar 2024

Study identifies CDK9's involvement in DNA repair during cell division

Researchers describe a newly-observed role for the protein Cyclin Dependent Kinase 9 (CDK9) in regulating DNA repair during cellular division, where errors can become the origin of cancerous tumor growth.

14 Mar 2024

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

Common inherited genetic factors that predict cancer risk in the general population may also predict elevated risk of new cancers among childhood cancer survivors, according to a study led by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

7 Mar 2024

Research project receives 25 million U.S. dollars to develop drugs against childhood cancers

Cancer is one of the most common causes of death in children worldwide. A research team in which the University of Würzburg is involved wants to change this – and has now received substantial funding for its work.

6 Mar 2024

Researchers develop new algorithm to identify high-risk precancerous lesions on the fallopian tubes

6 Mar 2024

Comparing CEUS imaging features in patients with hepatic lymphoepithelioma-like carcinoma and HCC

Announcing a new article publication for BIO Integration journal. Primary hepatic lymphoepithelioma-like carcinoma (LELC) is a malignant tumor with a low incidence, but the number of case reports has increased in recent years.

5 Mar 2024

Nomogram could be a game-changer for predicting alcohol-related liver cancer risk

Liver cancer, unfortunately, is the sixth most common cancer and the third most frequent cause of cancer-related death globally.

5 Mar 2024

Sacituzumab govitecan plus platinum-based chemotherapy effective in multiple carcinomas

A new research paper was published in Oncotarget's Volume 15 on February 22, 2024, entitled, "Sacituzumab govitecan plus platinum-based chemotherapy mediates significant antitumor effects in triple-negative breast, urinary bladder, and small-cell lung carcinomas."

5 Mar 2024

New approach detects T cells in "cold" tumors, paves way for broader immunotherapy

Most cancers are thought to evade the immune system. These cancers don't carry very many mutations, and they aren't infiltrated by cancer-fighting immune cells. Scientists call these cancers immunologically "cold."

29 Feb 2024

Study reveals high prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from the Salento peninsula

A new research paper was published in Oncotarget's Volume 15 on February 22, 2024, entitled, "Prevalence and spectrum of germline BRCA1 and BRCA2 in a cohort of ovarian cancer patients from the Salento peninsula (Southern Italy): a matter of preventive health."

28 Feb 2024

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

People who have had a kidney transplant are at high risk for developing skin cancers. New research directed by investigators from the Johns Hopkins Kimmel Cancer Center is exploring the best combination of treatments to target skin cancers while preserving the transplanted organs.

28 Feb 2024

Green tea does not lower the risk of lung cancer

Whether green tea consumption was associated with a lower risk of lung cancer.

22 Feb 2024

Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

UT Health Science Center researchers Gabor Tigyi, MD, PhD, Harriet Van Vleet Endowment Professor in Basic Oncology Research, Junming Yue, PhD, associate professor in the Department of Pathology, Sue Chin Lee, PhD, in the Department of Physiology, and David Schwartz, MD, chair of the Department of Radiation Oncology, are part of a scientific leadership group awarded $20 million from the University of Tennessee-Oak Ridge Innovation Institute in partnership with Oak Ridge National Laboratory and the University of Tennessee, Knoxville, to develop new radiopharmaceutical therapies to treat cancer.

21 Feb 2024

Carcinoma News and Research

Further Reading

Rare variants in the YKT6 gene cause new neurological disorder, study finds

Study provides a hopeful direction for the management of penile squamous cell carcinoma

Study reveals e-cigarette users with limited smoking history show similar DNA alterations as smokers

Pembrolizumab enhances breast cancer treatment regardless of age or menopausal status

Immune cell protein identified as potential target for rare liver cancer treatment

Developing mRNA lipid nanoparticles for treating oral squamous cell carcinoma

New insights into upper tract urothelial carcinoma evolution and treatment

Researchers develop an algorithm to identify high-risk precancerous lesions on the fallopian tubes

Study identifies CDK9's involvement in DNA repair during cell division

Inherited genetic factors may predict elevated risk of new cancers among childhood cancer survivors

Research project receives 25 million U.S. dollars to develop drugs against childhood cancers

Researchers develop new algorithm to identify high-risk precancerous lesions on the fallopian tubes

Comparing CEUS imaging features in patients with hepatic lymphoepithelioma-like carcinoma and HCC

Nomogram could be a game-changer for predicting alcohol-related liver cancer risk

Sacituzumab govitecan plus platinum-based chemotherapy effective in multiple carcinomas

New approach detects T cells in "cold" tumors, paves way for broader immunotherapy

Study reveals high prevalence of BRCA1 and BRCA2 mutations in ovarian cancer patients from the Salento peninsula

Novel drug combination shows promise for treating advanced skin cancers in kidney transplant recipients

Green tea does not lower the risk of lung cancer

Collaborative project gets $20 million to develop new radiopharmaceutical cancer therapies

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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