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Blood proteins predict cancer risk seven years in advance, studies find

Two Cancer Research UK-funded studies from Oxford Population Health have discovered proteins in the blood that could warn people of cancer more than seven years before it is diagnosed.

15 May 2024

3D printing technique enables the fabrication of customized pharmaceutical tablets

A new technique for 3D printing medication has enabled the printing of multiple drugs in a single tablet, paving the way for personalized pills that can deliver timed doses.

15 May 2024

Study uncovers unique platelet population linked to aging and blood clotting diseases

As people age, they become more prone to blood clotting diseases, when blood cells called platelets clump together when they don't need to and can cause major issues such as strokes and cardiovascular disease.

15 May 2024

Investigating age-associated gene expression changes in mouse sweat glands

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 8, entitled, "Characterization of age-associated gene expression changes in mouse sweat glands."

15 May 2024

Lactate is essential to buffering the effects of a carbohydrate meal, study shows

As a student competing in track and field at his Parlier high school, Robert Leija was obsessed with how to improve his performance and, in particular, prevent the buildup of lactic acid in his muscles during training.

15 May 2024

Tribal nations invest opioid settlement funds in traditional healing to treat addiction

Outside the Mi'kmaq Nation's health department sits a dome-shaped tent, built by hand from saplings and covered in black canvas.

15 May 2024

Genetic link identified between inflammatory bowel disease and Parkinson's disease

The researchers found, as expected from prior studies that LRRK2 is associated with IBD-PD and discovered new associations as well.

15 May 2024

More than 20,000 volunteers join effort to accelerate dementia drug development

More than 20,000 volunteers have been recruited to a resource aimed at speeding up the development of much-needed dementia drugs. The cohort will enable scientists in universities and industry to involve healthy individuals in clinical trials to test whether new drugs can slow the decline in various brain functions including memory and delay the onset of dementia.

15 May 2024

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Deaths from cancer or infections can occur when available treatments are ineffective. Once turned on, pregnane X receptor (PXR) activates the expression of genes encoding enzymes that metabolize external chemicals, including drugs.

14 May 2024

Innovative 'mini-brains' could revolutionize Alzheimer's diagnosis and treatment

Using an innovative new method, a University of Saskatchewan (USask) researcher is building tiny pseudo-organs from stem cells to help diagnose and treat Alzheimer's.

14 May 2024

Pharmacological treatment reduces specific crimes in adolescents with ADHD

A study in the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP), published by Elsevier, found that pharmacological treatment of attention-deficit/hyperactivity disorder (ADHD) reduced violence- and public-order related crimes.

14 May 2024

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Using human cells in laboratory rats, Michigan Medicine researchers have developed a functional model of thoracic aortic aneurysm, creating opportunities for more effective understanding of disease development and treatments for the potentially fatal condition, a study suggests.

14 May 2024

Racial and ethnic disparities in Alzheimer's diagnosis and CNS drug prescription

Compared to Black and Asian people, white and Hispanic people with Alzheimer's disease and related dementias were most likely to be diagnosed with symptoms like depression and agitation, according to a new study from the USC Schaeffer Center for Health Policy & Economics.

14 May 2024

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

People with a common heart condition were able to use significantly more oxygen while exercising after taking an investigational drug in an international clinical trial, according to a study published today in the New England Journal of Medicine.

14 May 2024

Study reveals unintended consequences of antibiotic choice in sepsis treatment

In emergency rooms and intensive care units across the country, clinicians make split-second decisions about which antibiotics to give a patient when a life-threatening infection is suspected.

14 May 2024

Clinical trial in Seattle aims to transform treatment approaches for pediatric IBD

With pediatric inflammatory bowel disease (IBD) diagnoses on the rise globally, a clinical trial in Seattle aims to transform treatment approaches through deep molecular profiling.

14 May 2024

Unraveling the genetic connection between IBD and Parkinson's disease

Researchers at the Icahn School of Medicine at Mount Sinai have made a significant discovery, identifying genetic connections between inflammatory bowel disease (IBD) and Parkinson's disease (PD).

14 May 2024

Exploring how intense ultrasound can release biological indicators of disease

Ultrasound imaging offers a valuable and noninvasive way to find and monitor cancerous tumors. However, much of the most crucial information about a cancer, such as specific cell types and mutations, cannot be learned from imaging and requires invasive and damaging biopsies.

14 May 2024

PlaqueTec and the Babraham Institute collaborate on early phase target discovery and development

Campus Innovation Award (CIA)-funded project evaluated lead compounds predicted to bind a pro-inflammatory protein discovered by PlaqueTec

From PlaqueTec 14 May 2024

Metabolomic analysis sheds light on gut microbes' role in cardiovascular disease risk

The effect of gut bacteria on non-high-density lipoprotein cholesterol (non-HDL-c) variations.

14 May 2024

Drugs News and Research

Blood proteins predict cancer risk seven years in advance, studies find

3D printing technique enables the fabrication of customized pharmaceutical tablets

Study uncovers unique platelet population linked to aging and blood clotting diseases

Investigating age-associated gene expression changes in mouse sweat glands

Lactate is essential to buffering the effects of a carbohydrate meal, study shows

Tribal nations invest opioid settlement funds in traditional healing to treat addiction

Genetic link identified between inflammatory bowel disease and Parkinson's disease

More than 20,000 volunteers join effort to accelerate dementia drug development

St. Jude researchers unveil mechanisms to block PXR and enhance drug potency

Innovative 'mini-brains' could revolutionize Alzheimer's diagnosis and treatment

Pharmacological treatment reduces specific crimes in adolescents with ADHD

Human cell-based model of thoracic aortic aneurysm offers new opportunities for drug development

Racial and ethnic disparities in Alzheimer's diagnosis and CNS drug prescription

Investigational drug shows promise in increasing oxygen uptake for patients with heart condition

Study reveals unintended consequences of antibiotic choice in sepsis treatment

Clinical trial in Seattle aims to transform treatment approaches for pediatric IBD

Unraveling the genetic connection between IBD and Parkinson's disease

Exploring how intense ultrasound can release biological indicators of disease

PlaqueTec and the Babraham Institute collaborate on early phase target discovery and development

Metabolomic analysis sheds light on gut microbes' role in cardiovascular disease risk

Drug Discovery - Second Edition eBook

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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